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The map label for this gene is argC [H]

Identifier: 187927153

GI number: 187927153

Start: 54691

End: 55704

Strand: Direct

Name: argC [H]

Synonym: Rpic_0043

Alternate gene names: 187927153

Gene position: 54691-55704 (Clockwise)

Preceding gene: 187927152

Following gene: 187927157

Centisome position: 1.39

GC content: 66.96

Gene sequence:

>1014_bases
ATGGCATTCAAGGTTTTCGTCGACGGTCAGGAAGGCACCACCGGCCTTCGCCTGCTCGATTATCTGTCGCAGCGCGACGA
TATCGAGCTGCTGCGCATCGCCGAAGACAAGCGCAAGGATTCTGCCGAGCGCGCCAAATTCCTGAATGCCGCCGATGTCG
CATTCCTGTGCCTGCCGGACGTCGCCTCGCGCGAGGCCGTCTCGCTGGTCAACAACCCGAACACCTGCATCATCGACGCC
AGCACCGCGTTCCGCACGTCGGACGACTGGGTCTACGGCCTGCCCGAACTGGCCCAGGGCCAGCGCGAGCGCCTGCGTAA
CACCAAGCGCATCGCCGTGCCGGGCTGCCACGCCAGTGCGTTCGTGCTGCTGATGCGTCCGCTGGTGGACGCGGGCATCG
TCCCGGCCGACTACCCGGTCACCGCGTTCTCGCTGACCGGCTACAGCGGCGGCGGCAAGCAGATGATTGCCGACTACCTC
GCCGCCAATAACCCGAAGCTCGACAGCCCGCGTCCGTACGCGCTGGCGCTGGCGCACAAGCACCTGCCGGAGATGCGCGT
GCAGAGCAAGCTGTCGCTCGCACCGATCTTCACGCCGGTCGTCGGCAATTTCCTCAAGGGCCTGGCCGTGACGATCGGCC
TGCACCCGCAACACCTGGCGCGCAAGGCGAGCCCGGCGGACATCGCCCGCGTGCTGGCCGATTACTACCAGGGCGAGCAG
TTCATCCGCGTGGCGCCGGCCGACAACGTTGCGACGCTCGACAACGGCTTCTTCGATGTGCAGGGCGCCAACGACACCAA
CCGTGCCGACCTGTTCGTGTTCGGTTCGGACGAGCGCATGGTCGTCACCGCGCGTCTGGACAACCTGGGCAAGGGCGCGG
CGGGCGCAGCGGTGCAATGCATGAACGTGCATCTCGGTGTGGATGAGGCGACGAGCCTGCATGTGGAAGCGCCGGTTCCC
GCAGCAGGCGCCGAGCACACCGTGCGCGAAGCCGCGCCGGGTTTCGCGAGCTGA

Upstream 100 bases:

>100_bases
GCCGCGGAAATGTCTTCGTCAGCCGCTACAATGCAAACCTCACGCGCCGGCATCGCTTGCCGGCGTTGTCTTTGGCCCCC
AGTTTTTTAGCGAGATCACC

Downstream 100 bases:

>100_bases
TCGCCGCCTGAGCGGAAACGAAAAACGCGCCTTCGGGCGCGTTTTTCTTTGGCCGTTTTGACGACCCGCGGCTTACTTGC
TCTGCGCCCCCGCCGGGATG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDKRKDSAERAKFLNAADVAFLCLPDVASREAVSLVNNPNTCIIDA
STAFRTSDDWVYGLPELAQGQRERLRNTKRIAVPGCHASAFVLLMRPLVDAGIVPADYPVTAFSLTGYSGGGKQMIADYL
AANNPKLDSPRPYALALAHKHLPEMRVQSKLSLAPIFTPVVGNFLKGLAVTIGLHPQHLARKASPADIARVLADYYQGEQ
FIRVAPADNVATLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVP
AAGAEHTVREAAPGFAS

Sequences:

>Translated_337_residues
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDKRKDSAERAKFLNAADVAFLCLPDVASREAVSLVNNPNTCIIDA
STAFRTSDDWVYGLPELAQGQRERLRNTKRIAVPGCHASAFVLLMRPLVDAGIVPADYPVTAFSLTGYSGGGKQMIADYL
AANNPKLDSPRPYALALAHKHLPEMRVQSKLSLAPIFTPVVGNFLKGLAVTIGLHPQHLARKASPADIARVLADYYQGEQ
FIRVAPADNVATLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVP
AAGAEHTVREAAPGFAS
>Mature_336_residues
AFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDKRKDSAERAKFLNAADVAFLCLPDVASREAVSLVNNPNTCIIDAS
TAFRTSDDWVYGLPELAQGQRERLRNTKRIAVPGCHASAFVLLMRPLVDAGIVPADYPVTAFSLTGYSGGGKQMIADYLA
ANNPKLDSPRPYALALAHKHLPEMRVQSKLSLAPIFTPVVGNFLKGLAVTIGLHPQHLARKASPADIARVLADYYQGEQF
IRVAPADNVATLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQCMNVHLGVDEATSLHVEAPVPA
AGAEHTVREAAPGFAS

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=303, Percent_Identity=28.7128712871287, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=304, Percent_Identity=28.6184210526316, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 36212; Mature: 36080

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDKRKDSAERAKFLNAADVAFLCLPD
CEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVNNPNTCIIDASTAFRTSDDWVYGLPELAQGQRERLRNTKRIAVPGCHASA
CCCCHHHHHCCCCCEEEEECCCCEECCCCCEECCHHHHHHHHHHHCCCCEEEECCCCHHH
FVLLMRPLVDAGIVPADYPVTAFSLTGYSGGGKQMIADYLAANNPKLDSPRPYALALAHK
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHH
HLPEMRVQSKLSLAPIFTPVVGNFLKGLAVTIGLHPQHLARKASPADIARVLADYYQGEQ
CCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCE
FIRVAPADNVATLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQC
EEEEECCCCEEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEE
MNVHLGVDEATSLHVEAPVPAAGAEHTVREAAPGFAS
EEEEECCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
AFKVFVDGQEGTTGLRLLDYLSQRDDIELLRIAEDKRKDSAERAKFLNAADVAFLCLPD
EEEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVNNPNTCIIDASTAFRTSDDWVYGLPELAQGQRERLRNTKRIAVPGCHASA
CCCCHHHHHCCCCCEEEEECCCCEECCCCCEECCHHHHHHHHHHHCCCCEEEECCCCHHH
FVLLMRPLVDAGIVPADYPVTAFSLTGYSGGGKQMIADYLAANNPKLDSPRPYALALAHK
HHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHH
HLPEMRVQSKLSLAPIFTPVVGNFLKGLAVTIGLHPQHLARKASPADIARVLADYYQGEQ
CCHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCE
FIRVAPADNVATLDNGFFDVQGANDTNRADLFVFGSDERMVVTARLDNLGKGAAGAAVQC
EEEEECCCCEEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEE
MNVHLGVDEATSLHVEAPVPAAGAEHTVREAAPGFAS
EEEEECCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]