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The map label for this gene is exuR [H]

Identifier: 187927126

GI number: 187927126

Start: 28338

End: 29102

Strand: Direct

Name: exuR [H]

Synonym: Rpic_0016

Alternate gene names: 187927126

Gene position: 28338-29102 (Clockwise)

Preceding gene: 187927124

Following gene: 187927127

Centisome position: 0.72

GC content: 69.15

Gene sequence:

>765_bases
ATGCACAGCATTCCATCCTCCGTCGCGCAAGCACTCCAGCAACGCATCCTGAGTGGCGAGTACCCCAGTGGCAGCCGCCT
GCCGCCGCAGCGTGAGTTGGCGGAAAGCCTGGGCGTGAGCCGCGCGTCGTTGCGCGAGGCGCTCACCGTGCTCGAAACGC
TGGGCCTGGTGGACATCCTCCCCAGCCGGGGCGTGGTGGTGCGCGGCCAGAAGTTCGGCGCAGAAGGGGCGAGTGCAGAG
CGCATGCACCGGCCGTTTGCCACGCCCGCGCTGGGCACGCTGTCGCCGCGTCAGTTGATCGAGCTGCGCCTGGTGCTGGA
GCCCGGCTGGACGGCACTGGCCGCCGCGCGCATGCATGCCGCCGGCCTGCGCCACCTGCAGTGGTTGCAGCAGCAGTTGG
CCCATGCGTTGGAGCGCAATGATTTGCTAAGCGCGGCAGAGGCGGATTTGCACTTCCACCTGCTGCTCGCGCAGTTGTCC
GGCAACCCGGGCTTGATGGCAATGGCCGGCCAGTTGGAACACGCCATCGGCCACAGCCTGCGCCTGCCCTTTGCCCGCAA
CGGCGCAGACGACCACCCCGCGCACGAGCACGACGCCATCGTGCAGGCCATTGCCGCGGGCGATGTCGCCGCCAGCGCAG
AGGCGATGCGTGCGCATCTGCTGTCGGCCGCGCGCCGCAGCGGCATTGATCTGACTGCGCCGCCCGCCACGCCCGAACCC
ATGCAGCACGAACCGGCTTCCTTTCGCCTCGCCTCGATTTCCTGA

Upstream 100 bases:

>100_bases
ATACCGCGCAACACGCAGCTTAATGCTGCATGGCACAAAACTCGCATAAGCCGTGGGCGACCGGTCAGACCACGACCGTG
TCTTTCTCCAATCTCGGCGC

Downstream 100 bases:

>100_bases
TCCTGAATTTCCTGAAGGAGTTTTTGAATGACCCGCATCACTGCCCGCCACGCTTCGCGCCCCACCTCGCGTCGCTTCTT
CCTCCATGCCGTCATGGCGG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MHSIPSSVAQALQQRILSGEYPSGSRLPPQRELAESLGVSRASLREALTVLETLGLVDILPSRGVVVRGQKFGAEGASAE
RMHRPFATPALGTLSPRQLIELRLVLEPGWTALAAARMHAAGLRHLQWLQQQLAHALERNDLLSAAEADLHFHLLLAQLS
GNPGLMAMAGQLEHAIGHSLRLPFARNGADDHPAHEHDAIVQAIAAGDVAASAEAMRAHLLSAARRSGIDLTAPPATPEP
MQHEPASFRLASIS

Sequences:

>Translated_254_residues
MHSIPSSVAQALQQRILSGEYPSGSRLPPQRELAESLGVSRASLREALTVLETLGLVDILPSRGVVVRGQKFGAEGASAE
RMHRPFATPALGTLSPRQLIELRLVLEPGWTALAAARMHAAGLRHLQWLQQQLAHALERNDLLSAAEADLHFHLLLAQLS
GNPGLMAMAGQLEHAIGHSLRLPFARNGADDHPAHEHDAIVQAIAAGDVAASAEAMRAHLLSAARRSGIDLTAPPATPEP
MQHEPASFRLASIS
>Mature_254_residues
MHSIPSSVAQALQQRILSGEYPSGSRLPPQRELAESLGVSRASLREALTVLETLGLVDILPSRGVVVRGQKFGAEGASAE
RMHRPFATPALGTLSPRQLIELRLVLEPGWTALAAARMHAAGLRHLQWLQQQLAHALERNDLLSAAEADLHFHLLLAQLS
GNPGLMAMAGQLEHAIGHSLRLPFARNGADDHPAHEHDAIVQAIAAGDVAASAEAMRAHLLSAARRSGIDLTAPPATPEP
MQHEPASFRLASIS

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994961, Length=220, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87082208, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790780, Length=232, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27083; Mature: 27083

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSIPSSVAQALQQRILSGEYPSGSRLPPQRELAESLGVSRASLREALTVLETLGLVDIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
PSRGVVVRGQKFGAEGASAERMHRPFATPALGTLSPRQLIELRLVLEPGWTALAAARMHA
CCCCEEEECHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHH
AGLRHLQWLQQQLAHALERNDLLSAAEADLHFHLLLAQLSGNPGLMAMAGQLEHAIGHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
RLPFARNGADDHPAHEHDAIVQAIAAGDVAASAEAMRAHLLSAARRSGIDLTAPPATPEP
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
MQHEPASFRLASIS
CCCCCCCEEEECCC
>Mature Secondary Structure
MHSIPSSVAQALQQRILSGEYPSGSRLPPQRELAESLGVSRASLREALTVLETLGLVDIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
PSRGVVVRGQKFGAEGASAERMHRPFATPALGTLSPRQLIELRLVLEPGWTALAAARMHA
CCCCEEEECHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHH
AGLRHLQWLQQQLAHALERNDLLSAAEADLHFHLLLAQLSGNPGLMAMAGQLEHAIGHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCE
RLPFARNGADDHPAHEHDAIVQAIAAGDVAASAEAMRAHLLSAARRSGIDLTAPPATPEP
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
MQHEPASFRLASIS
CCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA