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The map label for this gene is spoVD [H]

Identifier: 187918015

GI number: 187918015

Start: 134714

End: 136591

Strand: Direct

Name: spoVD [H]

Synonym: BH0136

Alternate gene names: 187918015

Gene position: 134714-136591 (Clockwise)

Preceding gene: 187918013

Following gene: 187918021

Centisome position: 14.61

GC content: 28.81

Gene sequence:

>1878_bases
ATGCATAAAAATTTTGCTAGCAGCTTAAGACTAAATATTGTTCTCATAATTTTCCTCACAATAACACTACTAACCATTTA
TAAATATTTTATGCTAATGTCCTCAAAAGACATACAATATTTTTCTCAAAATATAAATCACATTTCAAAAAGAGGCAACA
TTTATGATAGAAATGGTAAAATAATAGCCTTCTCATCAAAATCACATTCTATAGGAACGGATCCAAATAAAATAAAAAAT
ATTGTAAATACATCAGAAACTCTTGGTGCAATACTGAAAATTGAGCCTCAAATACTTAAAAAAAAACTGTCTTCAAAAAA
AGGATTCATATATATAAAAAGAAAAGTAACAAGAGAAGAATCTGAACTAATTAAAAGAATTCAATCAGAAGGAAGATTAA
AAGACATCATACTTTATCCAGACTACACAAGGATCTATCCATTTAAAGAACTGACAAGCAATATTACGGGATTTGTAGGA
ACTGACAACATTGGGCTTGCAGGGATTGAACTTTCGCTAAACACCATATTAAATGAAGATCTTACAAAACAAAAATCTAT
AAATGAAAAATTAAGTACAAACAACATATACTTAACAATAGACATAGATCTTCAAAAAAGCATAAATCAAATAGCTAAAA
AATACTTTAACGAAAATAAGCCTGAAAACATGCTAGCTATAGTAATGGATGCTAAGAATGGAGAAATTTTATCAATGCTT
CAACTCCCACAATATGATGCCAATTACTATTCAAAATATCCTAAAGAAATATGGAACAATTTTGCAACTTCCCTAACATA
TGAACCTGGAAGTATTAATAAAATTTTTACAGTAGCTATTCTATTAGACAGTGGATTATTAAAATTAAATGAAAAATTTT
TAGATAATGGTATATACCAAAAAAAATTCAAATCGGGTGAAGTAGTTACAATTAAAACCTTAAATCCTCCTTATGACTAT
ATCGATCCTAGTGGGATTCTAATCTATTCATCAAATGTAGGAATAGCTCACATTACAGACAAAGTAAGTAATGAATATTT
CTACAATAAACTAATAGCCTTTGGGTTTGGAAAAAGAGTCGGATTTCCTTTCCCCGGAGAGACAAAAGGGATACTAACCC
ACCATTCAAAATGGTCGGGACGGAGTAAAGCCACAATCGGATTTGGACAAGAAATAGGAGTATCTGCCATTCAAATATTA
CAGGCTGCTAGCGTCTTAAGTAATGATGGGGTTATGTTAAAACCCAAAATCATAAAAAGAATAAGCAATGAAATGGAAAA
TACAATTCAAGAATTTCAAAAAGAAGAAATTAAAAAAGTAATATCTAAGCATACAGCAAAAGAGGTTTTAAAAATGATGC
GAGAAGTTGTAAATAAAGGAGGAATACCAAAACTTAAAATGAAAAATTTAAACATTTCAGCAAAAAGTGGAACTTCCCAA
GTGATTGATAAAAACACAGGCAAATATTCAGACGAAGATTACACGTCCTCAATACTAGTAATATATCCCACAGAAAATCC
AAAATACATTATATATGTTATATACAGATATCCTAAAAAGATAATATATGGAACAAGAATTGCTGCACCAATGGCAAAAG
AAATAATAGAATTGATTGAAAGTCAAAATAACAAAGATGAATACAATGAAATTAAAATTTCCTCAAAAATTAGCATACCA
AAACCCACAATAAAATACGACACAACAGAAACTCTACCAAACCTTACAGGGCTTTCAAAAAGGGATTTAATGAAAATTTT
AAACAAATATACAAACACAAAAATAAAGATAAAAGGAAATGGTTTTGTATATAAACAATCCCAACCACCCAATACAAAAT
TAAAAGATATAAACGAACTTGAAATAACCTTAAAATAA

Upstream 100 bases:

>100_bases
TATAATATTATAAATATGAGAAAAAATTAATCAAACATTAATACTAAAATCCTTAACTGTTAAATACTAATTATAATATA
AGGAGCATCTAAAATACTTA

Downstream 100 bases:

>100_bases
TTTAGGAAAATAAATTCTTTATCTCATTTTTATAAAGATTTAAAATATAATTACGCTTAACATCCATCTTAATAGACATC
TCCTTGCCTACTTCAAATGG

Product: cell division protein FtsI

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MHKNFASSLRLNIVLIIFLTITLLTIYKYFMLMSSKDIQYFSQNINHISKRGNIYDRNGKIIAFSSKSHSIGTDPNKIKN
IVNTSETLGAILKIEPQILKKKLSSKKGFIYIKRKVTREESELIKRIQSEGRLKDIILYPDYTRIYPFKELTSNITGFVG
TDNIGLAGIELSLNTILNEDLTKQKSINEKLSTNNIYLTIDIDLQKSINQIAKKYFNENKPENMLAIVMDAKNGEILSML
QLPQYDANYYSKYPKEIWNNFATSLTYEPGSINKIFTVAILLDSGLLKLNEKFLDNGIYQKKFKSGEVVTIKTLNPPYDY
IDPSGILIYSSNVGIAHITDKVSNEYFYNKLIAFGFGKRVGFPFPGETKGILTHHSKWSGRSKATIGFGQEIGVSAIQIL
QAASVLSNDGVMLKPKIIKRISNEMENTIQEFQKEEIKKVISKHTAKEVLKMMREVVNKGGIPKLKMKNLNISAKSGTSQ
VIDKNTGKYSDEDYTSSILVIYPTENPKYIIYVIYRYPKKIIYGTRIAAPMAKEIIELIESQNNKDEYNEIKISSKISIP
KPTIKYDTTETLPNLTGLSKRDLMKILNKYTNTKIKIKGNGFVYKQSQPPNTKLKDINELEITLK

Sequences:

>Translated_625_residues
MHKNFASSLRLNIVLIIFLTITLLTIYKYFMLMSSKDIQYFSQNINHISKRGNIYDRNGKIIAFSSKSHSIGTDPNKIKN
IVNTSETLGAILKIEPQILKKKLSSKKGFIYIKRKVTREESELIKRIQSEGRLKDIILYPDYTRIYPFKELTSNITGFVG
TDNIGLAGIELSLNTILNEDLTKQKSINEKLSTNNIYLTIDIDLQKSINQIAKKYFNENKPENMLAIVMDAKNGEILSML
QLPQYDANYYSKYPKEIWNNFATSLTYEPGSINKIFTVAILLDSGLLKLNEKFLDNGIYQKKFKSGEVVTIKTLNPPYDY
IDPSGILIYSSNVGIAHITDKVSNEYFYNKLIAFGFGKRVGFPFPGETKGILTHHSKWSGRSKATIGFGQEIGVSAIQIL
QAASVLSNDGVMLKPKIIKRISNEMENTIQEFQKEEIKKVISKHTAKEVLKMMREVVNKGGIPKLKMKNLNISAKSGTSQ
VIDKNTGKYSDEDYTSSILVIYPTENPKYIIYVIYRYPKKIIYGTRIAAPMAKEIIELIESQNNKDEYNEIKISSKISIP
KPTIKYDTTETLPNLTGLSKRDLMKILNKYTNTKIKIKGNGFVYKQSQPPNTKLKDINELEITLK
>Mature_625_residues
MHKNFASSLRLNIVLIIFLTITLLTIYKYFMLMSSKDIQYFSQNINHISKRGNIYDRNGKIIAFSSKSHSIGTDPNKIKN
IVNTSETLGAILKIEPQILKKKLSSKKGFIYIKRKVTREESELIKRIQSEGRLKDIILYPDYTRIYPFKELTSNITGFVG
TDNIGLAGIELSLNTILNEDLTKQKSINEKLSTNNIYLTIDIDLQKSINQIAKKYFNENKPENMLAIVMDAKNGEILSML
QLPQYDANYYSKYPKEIWNNFATSLTYEPGSINKIFTVAILLDSGLLKLNEKFLDNGIYQKKFKSGEVVTIKTLNPPYDY
IDPSGILIYSSNVGIAHITDKVSNEYFYNKLIAFGFGKRVGFPFPGETKGILTHHSKWSGRSKATIGFGQEIGVSAIQIL
QAASVLSNDGVMLKPKIIKRISNEMENTIQEFQKEEIKKVISKHTAKEVLKMMREVVNKGGIPKLKMKNLNISAKSGTSQ
VIDKNTGKYSDEDYTSSILVIYPTENPKYIIYVIYRYPKKIIYGTRIAAPMAKEIIELIESQNNKDEYNEIKISSKISIP
KPTIKYDTTETLPNLTGLSKRDLMKILNKYTNTKIKIKGNGFVYKQSQPPNTKLKDINELEITLK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=565, Percent_Identity=25.1327433628319, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1786854, Length=564, Percent_Identity=22.1631205673759, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71098; Mature: 71098

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKNFASSLRLNIVLIIFLTITLLTIYKYFMLMSSKDIQYFSQNINHISKRGNIYDRNGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCC
IIAFSSKSHSIGTDPNKIKNIVNTSETLGAILKIEPQILKKKLSSKKGFIYIKRKVTREE
EEEECCCCCCCCCCHHHHHHHHCCHHHHHHEEEECHHHHHHHHCCCCCEEEEEEECCCCH
SELIKRIQSEGRLKDIILYPDYTRIYPFKELTSNITGFVGTDNIGLAGIELSLNTILNED
HHHHHHHHHCCCEEEEEECCCCHHCCCHHHHHCCCCEEECCCCCCEEEEEEEHHHHHHHH
LTKQKSINEKLSTNNIYLTIDIDLQKSINQIAKKYFNENKPENMLAIVMDAKNGEILSML
HHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEE
QLPQYDANYYSKYPKEIWNNFATSLTYEPGSINKIFTVAILLDSGLLKLNEKFLDNGIYQ
CCCCCCCHHHHCCHHHHHHHHHHEEEECCCCCCHHEEEEEHHCCCHHHHHHHHHHCCHHH
KKFKSGEVVTIKTLNPPYDYIDPSGILIYSSNVGIAHITDKVSNEYFYNKLIAFGFGKRV
HHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCC
GFPFPGETKGILTHHSKWSGRSKATIGFGQEIGVSAIQILQAASVLSNDGVMLKPKIIKR
CCCCCCCCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHH
ISNEMENTIQEFQKEEIKKVISKHTAKEVLKMMREVVNKGGIPKLKMKNLNISAKSGTSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCHH
VIDKNTGKYSDEDYTSSILVIYPTENPKYIIYVIYRYPKKIIYGTRIAAPMAKEIIELIE
HHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHHHHH
SQNNKDEYNEIKISSKISIPKPTIKYDTTETLPNLTGLSKRDLMKILNKYTNTKIKIKGN
CCCCCCCHHEEEEECEECCCCCCEECCCHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECC
GFVYKQSQPPNTKLKDINELEITLK
EEEEECCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MHKNFASSLRLNIVLIIFLTITLLTIYKYFMLMSSKDIQYFSQNINHISKRGNIYDRNGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCC
IIAFSSKSHSIGTDPNKIKNIVNTSETLGAILKIEPQILKKKLSSKKGFIYIKRKVTREE
EEEECCCCCCCCCCHHHHHHHHCCHHHHHHEEEECHHHHHHHHCCCCCEEEEEEECCCCH
SELIKRIQSEGRLKDIILYPDYTRIYPFKELTSNITGFVGTDNIGLAGIELSLNTILNED
HHHHHHHHHCCCEEEEEECCCCHHCCCHHHHHCCCCEEECCCCCCEEEEEEEHHHHHHHH
LTKQKSINEKLSTNNIYLTIDIDLQKSINQIAKKYFNENKPENMLAIVMDAKNGEILSML
HHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEE
QLPQYDANYYSKYPKEIWNNFATSLTYEPGSINKIFTVAILLDSGLLKLNEKFLDNGIYQ
CCCCCCCHHHHCCHHHHHHHHHHEEEECCCCCCHHEEEEEHHCCCHHHHHHHHHHCCHHH
KKFKSGEVVTIKTLNPPYDYIDPSGILIYSSNVGIAHITDKVSNEYFYNKLIAFGFGKRV
HHCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCC
GFPFPGETKGILTHHSKWSGRSKATIGFGQEIGVSAIQILQAASVLSNDGVMLKPKIIKR
CCCCCCCCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHH
ISNEMENTIQEFQKEEIKKVISKHTAKEVLKMMREVVNKGGIPKLKMKNLNISAKSGTSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCHH
VIDKNTGKYSDEDYTSSILVIYPTENPKYIIYVIYRYPKKIIYGTRIAAPMAKEIIELIE
HHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHHHHH
SQNNKDEYNEIKISSKISIPKPTIKYDTTETLPNLTGLSKRDLMKILNKYTNTKIKIKGN
CCCCCCCHHEEEEECEECCCCCCEECCCHHHCCCCCCCCHHHHHHHHHHHCCCEEEEECC
GFVYKQSQPPNTKLKDINELEITLK
EEEEECCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]