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The map label for this gene is nadA [H]

Identifier: 187736627

GI number: 187736627

Start: 2618412

End: 2619347

Strand: Direct

Name: nadA [H]

Synonym: Amuc_2150

Alternate gene names: 187736627

Gene position: 2618412-2619347 (Clockwise)

Preceding gene: 187736623

Following gene: 187736628

Centisome position: 98.28

GC content: 57.59

Gene sequence:

>936_bases
ATGGCACCCTTTGACCTGAAAGAGGAAATCTTACGCCTGAAAGAAAAACGCAACGCCATCATTCTGGCGCACAGCTACCA
GACCGGGGATATCCAGGACATGGCCGACTACGTGGGCGATTCCCTGGGGCTGGCCTACAAGGCGCAGAATACGGATTGCG
ACGTGATCGCCTTCTGCGGCGTCCATTTCATGGCGGAAACCGCCAAAATTCTTAATCCGGACAAAACCGTCATCCTTCCG
GATGCTGATGCCGGCTGTTCCCTGGAAGCCTCCTGCGATGCCGGGGAACTGGAAGCCTTCTTAAAGGAAAACGCCCATAA
GAATTACTATGTAGTGGCGTATGTGAACTGCTCCATCGGCGTCAAGGCTCTGGCGGACGTAATCGTCACCTCCGGGAATG
CCGTAAAAATCGTCTCCCAGGCTCCGGAGGACCGCCCCATCCTGTTCGTCCCGGACCAGAATCTGGGTGCATGGGTAAGC
CGCCAGCTTGGCCGCCCCCTGGAACTGTGGAACGGGGCCTGCCACGTGCACATGGAGTTCACGCGGGACCAGATTCTTGC
CCTGAAAGAAAAACACCCCGGTGTGCCGGTAGTGGCCCATCCGGAATGCACGGAAGCCGTGCGCCTGCTGGCGGACCATA
TCTGCTCCACGGAAAAAATGATCCCCTATTGCACGGAAAACCCCGCCAAATCTTTCATCATTGTGACGGAATCCGGCATT
CTGCACCGTCTCCGCAAGCTGGTGCCGGGAAAAGAATTCATTCCCGCGCCCACGGAGCAATGCTCCTGCAGCACCTGCCC
GTACATGAAAATGAACACGCTGGAAAAACTGTACCTGGCCCTTCGGGACCTTTCTCCCGCCGTGGAACTGCCGAAAGACC
TGCGCAGAAGGGCGGAAGCCCCGCTGCTGCGCATGCTGGAGCAATCCCAATCCTGA

Upstream 100 bases:

>100_bases
GCGCCAGACTGTGCCACATTTCCCCCTTCCCGTCAACAAGCTCGCCCTGCATGGGACATGATGCTTGACTTGCCGGGGGC
TTCGCCCCATCTTTTCCCGC

Downstream 100 bases:

>100_bases
CCTCTGCCTTCCCCGCATGATACGCCTTTCAGACCACATCGCGGCCGCTGGCGGCTGGCTCTCCCTGGAAGCTTTCATGC
AGCTGGCCCTGCACCACCCG

Product: quinolinate synthetase complex, A subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAPFDLKEEILRLKEKRNAIILAHSYQTGDIQDMADYVGDSLGLAYKAQNTDCDVIAFCGVHFMAETAKILNPDKTVILP
DADAGCSLEASCDAGELEAFLKENAHKNYYVVAYVNCSIGVKALADVIVTSGNAVKIVSQAPEDRPILFVPDQNLGAWVS
RQLGRPLELWNGACHVHMEFTRDQILALKEKHPGVPVVAHPECTEAVRLLADHICSTEKMIPYCTENPAKSFIIVTESGI
LHRLRKLVPGKEFIPAPTEQCSCSTCPYMKMNTLEKLYLALRDLSPAVELPKDLRRRAEAPLLRMLEQSQS

Sequences:

>Translated_311_residues
MAPFDLKEEILRLKEKRNAIILAHSYQTGDIQDMADYVGDSLGLAYKAQNTDCDVIAFCGVHFMAETAKILNPDKTVILP
DADAGCSLEASCDAGELEAFLKENAHKNYYVVAYVNCSIGVKALADVIVTSGNAVKIVSQAPEDRPILFVPDQNLGAWVS
RQLGRPLELWNGACHVHMEFTRDQILALKEKHPGVPVVAHPECTEAVRLLADHICSTEKMIPYCTENPAKSFIIVTESGI
LHRLRKLVPGKEFIPAPTEQCSCSTCPYMKMNTLEKLYLALRDLSPAVELPKDLRRRAEAPLLRMLEQSQS
>Mature_310_residues
APFDLKEEILRLKEKRNAIILAHSYQTGDIQDMADYVGDSLGLAYKAQNTDCDVIAFCGVHFMAETAKILNPDKTVILPD
ADAGCSLEASCDAGELEAFLKENAHKNYYVVAYVNCSIGVKALADVIVTSGNAVKIVSQAPEDRPILFVPDQNLGAWVSR
QLGRPLELWNGACHVHMEFTRDQILALKEKHPGVPVVAHPECTEAVRLLADHICSTEKMIPYCTENPAKSFIIVTESGIL
HRLRKLVPGKEFIPAPTEQCSCSTCPYMKMNTLEKLYLALRDLSPAVELPKDLRRRAEAPLLRMLEQSQS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=313, Percent_Identity=38.0191693290735, Blast_Score=203, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34449; Mature: 34318

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPFDLKEEILRLKEKRNAIILAHSYQTGDIQDMADYVGDSLGLAYKAQNTDCDVIAFCG
CCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCHHCEEEEECCCCCCCHHHHH
VHFMAETAKILNPDKTVILPDADAGCSLEASCDAGELEAFLKENAHKNYYVVAYVNCSIG
HHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCC
VKALADVIVTSGNAVKIVSQAPEDRPILFVPDQNLGAWVSRQLGRPLELWNGACHVHMEF
HHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCHHHCCCEEEEEEEE
TRDQILALKEKHPGVPVVAHPECTEAVRLLADHICSTEKMIPYCTENPAKSFIIVTESGI
CCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHH
LHRLRKLVPGKEFIPAPTEQCSCSTCPYMKMNTLEKLYLALRDLSPAVELPKDLRRRAEA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCC
PLLRMLEQSQS
HHHHHHHHCCC
>Mature Secondary Structure 
APFDLKEEILRLKEKRNAIILAHSYQTGDIQDMADYVGDSLGLAYKAQNTDCDVIAFCG
CCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCHHCEEEEECCCCCCCHHHHH
VHFMAETAKILNPDKTVILPDADAGCSLEASCDAGELEAFLKENAHKNYYVVAYVNCSIG
HHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCC
VKALADVIVTSGNAVKIVSQAPEDRPILFVPDQNLGAWVSRQLGRPLELWNGACHVHMEF
HHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCHHHCCCEEEEEEEE
TRDQILALKEKHPGVPVVAHPECTEAVRLLADHICSTEKMIPYCTENPAKSFIIVTESGI
CCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHH
LHRLRKLVPGKEFIPAPTEQCSCSTCPYMKMNTLEKLYLALRDLSPAVELPKDLRRRAEA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCC
PLLRMLEQSQS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA