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The map label for this gene is queD [H]

Identifier: 187736623

GI number: 187736623

Start: 2613654

End: 2614106

Strand: Direct

Name: queD [H]

Synonym: Amuc_2146

Alternate gene names: 187736623

Gene position: 2613654-2614106 (Clockwise)

Preceding gene: 187736621

Following gene: 187736627

Centisome position: 98.11

GC content: 56.95

Gene sequence:

>453_bases
ATGGTCTACCGAATTTGCAAATCCATCGAACTGGAAAACGGGCATCTCCTGTCCAAACATCCCGGCAATTGCAAATTCCC
GCATGGCCATACGCGCTCCGTGGAAATGGTGTTCCGGGCGGAAACGCTGGATGCCAATGACATGGTGTTGGATTTCAAGG
CCGTCAAGCAAATGATGGGGGATTTCCTCCAGCAGTTTGACCACTCCCTGTGCGTGAATACGGAGGACCCCAATTACGCT
GCCTTCGTGGCCGCATACGGGGAGCGCATCATTCCCTTCGACCGGGAAGACCCCACCAGCGAGGTGATGGCACGCGTCAT
TTTCAATGTTGCCCGGCACGCGCTGGAAAAAGCCAGGGAGAACCCCGGCGAATATCCCGTGCGGGCCTGTGTTGAGCTGG
AACGCGTGCGCGTGTGGGAAACCAGCAGCTCCTGGGCGGAATATGGGGAATAA

Upstream 100 bases:

>100_bases
CGGAGCAGCGAAGCCCCGTCCCTCCGCACGCGGCAGGATAGGAACCAGACAGACTCTGATTGGGATTGCCCCGCACCCGC
GCCCACGTTATCCTGTCCTC

Downstream 100 bases:

>100_bases
CTGAAACAGCGCGCTTCCCGCCGGGAGGAACGCTCTGCAAAGATTCCCGGCCCCGCGGAAGGCACGGCCGCAATGCAGCC
ACCCCGGTGTTCATCCCTTA

Product: 6-pyruvoyl-tetrahydropterin synthase-like protein

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MVYRICKSIELENGHLLSKHPGNCKFPHGHTRSVEMVFRAETLDANDMVLDFKAVKQMMGDFLQQFDHSLCVNTEDPNYA
AFVAAYGERIIPFDREDPTSEVMARVIFNVARHALEKARENPGEYPVRACVELERVRVWETSSSWAEYGE

Sequences:

>Translated_150_residues
MVYRICKSIELENGHLLSKHPGNCKFPHGHTRSVEMVFRAETLDANDMVLDFKAVKQMMGDFLQQFDHSLCVNTEDPNYA
AFVAAYGERIIPFDREDPTSEVMARVIFNVARHALEKARENPGEYPVRACVELERVRVWETSSSWAEYGE
>Mature_150_residues
MVYRICKSIELENGHLLSKHPGNCKFPHGHTRSVEMVFRAETLDANDMVLDFKAVKQMMGDFLQQFDHSLCVNTEDPNYA
AFVAAYGERIIPFDREDPTSEVMARVIFNVARHALEKARENPGEYPVRACVELERVRVWETSSSWAEYGE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 17241; Mature: 17241

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYRICKSIELENGHLLSKHPGNCKFPHGHTRSVEMVFRAETLDANDMVLDFKAVKQMMG
CHHHHHHHEECCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHH
DFLQQFDHSLCVNTEDPNYAAFVAAYGERIIPFDREDPTSEVMARVIFNVARHALEKARE
HHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
NPGEYPVRACVELERVRVWETSSSWAEYGE
CCCCCHHHHHHHHHHHHEECCCCCHHHCCC
>Mature Secondary Structure
MVYRICKSIELENGHLLSKHPGNCKFPHGHTRSVEMVFRAETLDANDMVLDFKAVKQMMG
CHHHHHHHEECCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHH
DFLQQFDHSLCVNTEDPNYAAFVAAYGERIIPFDREDPTSEVMARVIFNVARHALEKARE
HHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
NPGEYPVRACVELERVRVWETSSSWAEYGE
CCCCCHHHHHHHHHHHHEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]