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The map label for this gene is exo I [H]

Identifier: 187736614

GI number: 187736614

Start: 2602446

End: 2604716

Strand: Reverse

Name: exo I [H]

Synonym: Amuc_2136

Alternate gene names: 187736614

Gene position: 2604716-2602446 (Counterclockwise)

Preceding gene: 187736615

Following gene: 187736612

Centisome position: 97.77

GC content: 56.85

Gene sequence:

>2271_bases
ATGAAGAAAAACCTATTCCTGATGATCGCCGTTCTTGCCGCGTCTCCCGTGATGGGGCAGGACGCCAAGCAGATTGCGGA
TTCCCTTTCCATCCCTCCGGTGAAAGCCGGAGCGAAGCAACTGCCCATGCCGAGCGTTTCCGGAGCCCAGATTAAATTGC
TGGGGGCCGACTATGAGCAGCTCGTCAACAGCAAAGGCAAGATAGCCCCTGTTATTTCAGATACCCCCGTCAACGTCAGC
TTCAAGGTGACCAAGGACGGCAAGGAAGCCGTCAGCAAAGATTATGAAATCATGCTGCAGGCTCCTCAGGCCGCCCAGGG
CAACCCCAAGCCGCGGATTATCCCGGAAATCCTGCAATGGAAGGGGGGACAGGGAGAATATAAGCTGGGGAATACGGTCA
CCATAGCATGCCCGGACAAGGAGCTGGGCAAATTGTTTGCGGCGGATATGGAAGACGTGCTGGGGAAGAAGGTCAAGCTT
GTCGCCCCCGGGGCGAAGGCGGATATTTCCCTTTCCCTGTTGAAGGGCGGCAATCTGGGCAGGGAAGGATACCGGCTCCA
GATTGCCAGGGACGGCGTCCGCCTTGGCGCGGCGGCTCCCACCGGCCTGTTCTGGGGCACGCGCACCCTGCTGCAGATGC
TCCGCCAGACGCCCGGCAGCGTGCCCTGCGGCACGGCCGTGGATTTTCCGCGCTACCAGCTCCGCGGGTTCATGCTTGAT
GTCGCGCGCACGCCTTACCCCCTCAGTTACCTGAAGGACGTGATCCGCACCATGGCCTGGTACAAGATGAATGACCTGCA
CCTGGTCATCAACAACAACTATATTTTCCACGAACACTATGTGGACAACGGCCATGATCCGTTCAAGGAAAGCTATGCGG
CTTTCCGCCTGGAATCCAAAATGAAGGGAAAGGACGGAACGCCCCTGACAGCCAGGGATCTTTTTTATACCAAGAAGGAA
TTTGCCGACCTGGTCAGCTATGCCAGAAAGTACGGCGTCAATATTGTTCCGGAGTTCGACACGCCGGGGCATGCCCTTTC
CTTTACGCGCCTGCGGCCTGATCTCATTTATAAAGGGCCCATGAATCATGAGAAGCGCCGCTGCGAGATGCTGGACGCCG
CCAACCCGGAAACGATCGACCTGGTGAGCAAGGTTTTTGACGAATACATGCTGAAGGATCCCAAACTGGGTCGTCCCGTG
TTCGCGGACTGCGGCGTGGTGCATGTGGGGGCGGATGAATTTTATGGGGACAAGGAAGATTACCGCCACTTTGCAAACGC
CGTGCTCACCCATGCCCTCAAGCGCGGTTATACGCCCCGCATCTGGGGAAGCCTCAGCGCCAAGCCGGGCAAGACCCCGG
TGGTCAGCAAAGGGGTCCAGATGAACCTTTGGAGCACCGGCTGGATGAAAGCATGGGAAGCCGTCAACCAGGGCTATGAT
GTGATCAATACGAACGATGGAGCCCTTTATATCGTTCCCTTTGCCGGCTACTACCGGATGGACAGAAACCATAAGGGGCT
GTACAATAACTGGATTCCCAACCGCATCGGCAATGAAACGCTGCCTTCCGGGCATCCCCAGCTCCTCGGAGGCACCTTCG
CCGTCTGGAATGATGAAACGGACATTATGCATACGGGGTACGCGCCTTATGACATTTGGGGGATCATTTCCGGTTCCATG
GACGTGCTCAGCCAGAAACTGTGGGGAACCGCCAAAGCTCCGGATACGTTTGAACAGCATCGCGAGCTGGTTTCCTCCAT
CGGCAACGCTCCGCGCACCAATCCCCTGCACAAATGGAAAGACAGCCAGCCCTTGACGGTGAAGCCTTCCTCCCTCCCCC
AGAAGCTGGACAAACCTGCCCTGGGGCCGAATTACCGCCTGACCATGGAACTGGAATTGACTGCCGCTCCGGAAGGGAAG
GAGCAGGTGCTGCTTGCTGCGCCTGAGGGCGAATTGCTTGCGGTCATGAAGGACGGCACCGTCGGATTCCGCCGTGACGA
TTCTCTGGAATTTTCCTTCGGCGCCAAGCTTCCCGTAGGCAAGAAGGTCAAGGTGGAAATTGTGGGAGAACCGGAGAAAA
CCAGCCTGTTGCTTGACGGGGAACCTGCCGGAACTGCCGTGCTGAAGAATTTTTCCGACAAGTCCAAGGATTTTTCGGAC
AAATTCAAGCATCGTCCCAAAGTTCACCGTTCCACGTTCATTCTGCCTCTGAAGGAACTTGGCTCCTCCTTCCAGGGGAA
GGTGTTCCATATGAACGTACAGCCGTTGTAA

Upstream 100 bases:

>100_bases
AATTCTTCCGCTTTTCTCCCTTTCTCTGCAAGAAAGGGGCGGCGGGCGCGTAGTTTTTGGAGCAAATCAGACATTTCCTT
TTCCTAAACAAGACTAAAAC

Downstream 100 bases:

>100_bases
TTCCCGGCATTTGGCCAGGCCGCCGCCTTTGACGGGGCGGCCTGCAGCCCGGCATCCCTGCCGCATGGGATGCCGGGTTT
CTTTTTATGGAAGGGGGGAG

Product: Glycoside hydrolase, family 20, catalytic core

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MKKNLFLMIAVLAASPVMGQDAKQIADSLSIPPVKAGAKQLPMPSVSGAQIKLLGADYEQLVNSKGKIAPVISDTPVNVS
FKVTKDGKEAVSKDYEIMLQAPQAAQGNPKPRIIPEILQWKGGQGEYKLGNTVTIACPDKELGKLFAADMEDVLGKKVKL
VAPGAKADISLSLLKGGNLGREGYRLQIARDGVRLGAAAPTGLFWGTRTLLQMLRQTPGSVPCGTAVDFPRYQLRGFMLD
VARTPYPLSYLKDVIRTMAWYKMNDLHLVINNNYIFHEHYVDNGHDPFKESYAAFRLESKMKGKDGTPLTARDLFYTKKE
FADLVSYARKYGVNIVPEFDTPGHALSFTRLRPDLIYKGPMNHEKRRCEMLDAANPETIDLVSKVFDEYMLKDPKLGRPV
FADCGVVHVGADEFYGDKEDYRHFANAVLTHALKRGYTPRIWGSLSAKPGKTPVVSKGVQMNLWSTGWMKAWEAVNQGYD
VINTNDGALYIVPFAGYYRMDRNHKGLYNNWIPNRIGNETLPSGHPQLLGGTFAVWNDETDIMHTGYAPYDIWGIISGSM
DVLSQKLWGTAKAPDTFEQHRELVSSIGNAPRTNPLHKWKDSQPLTVKPSSLPQKLDKPALGPNYRLTMELELTAAPEGK
EQVLLAAPEGELLAVMKDGTVGFRRDDSLEFSFGAKLPVGKKVKVEIVGEPEKTSLLLDGEPAGTAVLKNFSDKSKDFSD
KFKHRPKVHRSTFILPLKELGSSFQGKVFHMNVQPL

Sequences:

>Translated_756_residues
MKKNLFLMIAVLAASPVMGQDAKQIADSLSIPPVKAGAKQLPMPSVSGAQIKLLGADYEQLVNSKGKIAPVISDTPVNVS
FKVTKDGKEAVSKDYEIMLQAPQAAQGNPKPRIIPEILQWKGGQGEYKLGNTVTIACPDKELGKLFAADMEDVLGKKVKL
VAPGAKADISLSLLKGGNLGREGYRLQIARDGVRLGAAAPTGLFWGTRTLLQMLRQTPGSVPCGTAVDFPRYQLRGFMLD
VARTPYPLSYLKDVIRTMAWYKMNDLHLVINNNYIFHEHYVDNGHDPFKESYAAFRLESKMKGKDGTPLTARDLFYTKKE
FADLVSYARKYGVNIVPEFDTPGHALSFTRLRPDLIYKGPMNHEKRRCEMLDAANPETIDLVSKVFDEYMLKDPKLGRPV
FADCGVVHVGADEFYGDKEDYRHFANAVLTHALKRGYTPRIWGSLSAKPGKTPVVSKGVQMNLWSTGWMKAWEAVNQGYD
VINTNDGALYIVPFAGYYRMDRNHKGLYNNWIPNRIGNETLPSGHPQLLGGTFAVWNDETDIMHTGYAPYDIWGIISGSM
DVLSQKLWGTAKAPDTFEQHRELVSSIGNAPRTNPLHKWKDSQPLTVKPSSLPQKLDKPALGPNYRLTMELELTAAPEGK
EQVLLAAPEGELLAVMKDGTVGFRRDDSLEFSFGAKLPVGKKVKVEIVGEPEKTSLLLDGEPAGTAVLKNFSDKSKDFSD
KFKHRPKVHRSTFILPLKELGSSFQGKVFHMNVQPL
>Mature_756_residues
MKKNLFLMIAVLAASPVMGQDAKQIADSLSIPPVKAGAKQLPMPSVSGAQIKLLGADYEQLVNSKGKIAPVISDTPVNVS
FKVTKDGKEAVSKDYEIMLQAPQAAQGNPKPRIIPEILQWKGGQGEYKLGNTVTIACPDKELGKLFAADMEDVLGKKVKL
VAPGAKADISLSLLKGGNLGREGYRLQIARDGVRLGAAAPTGLFWGTRTLLQMLRQTPGSVPCGTAVDFPRYQLRGFMLD
VARTPYPLSYLKDVIRTMAWYKMNDLHLVINNNYIFHEHYVDNGHDPFKESYAAFRLESKMKGKDGTPLTARDLFYTKKE
FADLVSYARKYGVNIVPEFDTPGHALSFTRLRPDLIYKGPMNHEKRRCEMLDAANPETIDLVSKVFDEYMLKDPKLGRPV
FADCGVVHVGADEFYGDKEDYRHFANAVLTHALKRGYTPRIWGSLSAKPGKTPVVSKGVQMNLWSTGWMKAWEAVNQGYD
VINTNDGALYIVPFAGYYRMDRNHKGLYNNWIPNRIGNETLPSGHPQLLGGTFAVWNDETDIMHTGYAPYDIWGIISGSM
DVLSQKLWGTAKAPDTFEQHRELVSSIGNAPRTNPLHKWKDSQPLTVKPSSLPQKLDKPALGPNYRLTMELELTAAPEGK
EQVLLAAPEGELLAVMKDGTVGFRRDDSLEFSFGAKLPVGKKVKVEIVGEPEKTSLLLDGEPAGTAVLKNFSDKSKDFSD
KFKHRPKVHRSTFILPLKELGSSFQGKVFHMNVQPL

Specific function: Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D- glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta- GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc), aryl-beta-GalNAc a

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=262, Percent_Identity=28.6259541984733, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI4504373, Length=238, Percent_Identity=26.0504201680672, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45551090, Length=434, Percent_Identity=22.8110599078341, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653074, Length=434, Percent_Identity=22.8110599078341, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 83780; Mature: 83780

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNLFLMIAVLAASPVMGQDAKQIADSLSIPPVKAGAKQLPMPSVSGAQIKLLGADYEQ
CCCCCEEEEEHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHH
LVNSKGKIAPVISDTPVNVSFKVTKDGKEAVSKDYEIMLQAPQAAQGNPKPRIIPEILQW
HHCCCCCEEEEECCCCCEEEEEECCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCC
KGGQGEYKLGNTVTIACPDKELGKLFAADMEDVLGKKVKLVAPGAKADISLSLLKGGNLG
CCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCC
REGYRLQIARDGVRLGAAAPTGLFWGTRTLLQMLRQTPGSVPCGTAVDFPRYQLRGFMLD
CCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEE
VARTPYPLSYLKDVIRTMAWYKMNDLHLVINNNYIFHEHYVDNGHDPFKESYAAFRLESK
CCCCCCCHHHHHHHHHHHHHEEECCEEEEEECCEEEEECCCCCCCCHHHHHHHHHEEHHH
MKGKDGTPLTARDLFYTKKEFADLVSYARKYGVNIVPEFDTPGHALSFTRLRPDLIYKGP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCEEEECC
MNHEKRRCEMLDAANPETIDLVSKVFDEYMLKDPKLGRPVFADCGVVHVGADEFYGDKED
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHCCCHHH
YRHFANAVLTHALKRGYTPRIWGSLSAKPGKTPVVSKGVQMNLWSTGWMKAWEAVNQGYD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
VINTNDGALYIVPFAGYYRMDRNHKGLYNNWIPNRIGNETLPSGHPQLLGGTFAVWNDET
EEECCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEECCCC
DIMHTGYAPYDIWGIISGSMDVLSQKLWGTAKAPDTFEQHRELVSSIGNAPRTNPLHKWK
CEEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DSQPLTVKPSSLPQKLDKPALGPNYRLTMELELTAAPEGKEQVLLAAPEGELLAVMKDGT
CCCCCEECCCHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCEEEEEECCC
VGFRRDDSLEFSFGAKLPVGKKVKVEIVGEPEKTSLLLDGEPAGTAVLKNFSDKSKDFSD
CCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHCCCCCCCCHHH
KFKHRPKVHRSTFILPLKELGSSFQGKVFHMNVQPL
HHHCCCCCCCCEEEEEHHHCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKKNLFLMIAVLAASPVMGQDAKQIADSLSIPPVKAGAKQLPMPSVSGAQIKLLGADYEQ
CCCCCEEEEEHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHH
LVNSKGKIAPVISDTPVNVSFKVTKDGKEAVSKDYEIMLQAPQAAQGNPKPRIIPEILQW
HHCCCCCEEEEECCCCCEEEEEECCCCHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCC
KGGQGEYKLGNTVTIACPDKELGKLFAADMEDVLGKKVKLVAPGAKADISLSLLKGGNLG
CCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCC
REGYRLQIARDGVRLGAAAPTGLFWGTRTLLQMLRQTPGSVPCGTAVDFPRYQLRGFMLD
CCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEE
VARTPYPLSYLKDVIRTMAWYKMNDLHLVINNNYIFHEHYVDNGHDPFKESYAAFRLESK
CCCCCCCHHHHHHHHHHHHHEEECCEEEEEECCEEEEECCCCCCCCHHHHHHHHHEEHHH
MKGKDGTPLTARDLFYTKKEFADLVSYARKYGVNIVPEFDTPGHALSFTRLRPDLIYKGP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCEEEECC
MNHEKRRCEMLDAANPETIDLVSKVFDEYMLKDPKLGRPVFADCGVVHVGADEFYGDKED
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHCCCHHH
YRHFANAVLTHALKRGYTPRIWGSLSAKPGKTPVVSKGVQMNLWSTGWMKAWEAVNQGYD
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
VINTNDGALYIVPFAGYYRMDRNHKGLYNNWIPNRIGNETLPSGHPQLLGGTFAVWNDET
EEECCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEECCCC
DIMHTGYAPYDIWGIISGSMDVLSQKLWGTAKAPDTFEQHRELVSSIGNAPRTNPLHKWK
CEEECCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DSQPLTVKPSSLPQKLDKPALGPNYRLTMELELTAAPEGKEQVLLAAPEGELLAVMKDGT
CCCCCEECCCHHHHHHCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCEEEEEECCC
VGFRRDDSLEFSFGAKLPVGKKVKVEIVGEPEKTSLLLDGEPAGTAVLKNFSDKSKDFSD
CCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHCCCCCCCCHHH
KFKHRPKVHRSTFILPLKELGSSFQGKVFHMNVQPL
HHHCCCCCCCCEEEEEHHHCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969205 [H]