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The map label for this gene is ftsK [H]

Identifier: 187736554

GI number: 187736554

Start: 2523252

End: 2525708

Strand: Reverse

Name: ftsK [H]

Synonym: Amuc_2076

Alternate gene names: 187736554

Gene position: 2525708-2523252 (Counterclockwise)

Preceding gene: 187736584

Following gene: 187736553

Centisome position: 94.81

GC content: 57.55

Gene sequence:

>2457_bases
ATGGTATGGGGCGTCGTGTCTTTGTTGGGGGGGGCGGCTCTTCTGGCTGCTATGCTGACATTTGATGTGCGGGAAATAGG
CTGGAGTTATTTAAATGGTTCCGGGCAGGTAATTCCGGGTACCTCCAATGTGCTGGGAACGGTAGGATTGTATGGTGCGG
GGATTTTTTATTGGACGCTGGGAGGCATGGCTTGGATGCTGGTTGTTCTGTTGGAGTGGTGGGGGCTTTACCGTCTGCTC
CACTATGGAAGACTGCCCCGCAGCGTGGTTTACGGCGGTTTGTTCCTGCTGTTGTTCGGATGCCTGTTTCTGGCAGCCGG
GCATGTGCCGGGAAATGAGTGGGTGGCTCGCCACCAGGTCCAGGGGGCCGGGGGGCTGGTGGGTCATTTGCTGGGAACTG
GTTTGTTTTTTCCGTTGGCCGGCAGATCCGCTGTGCTGGCGTTTTCCGGGCTGGGCTATTTGCTGGCCTTGGTTTATGCC
GCCGGGATGCGTCCCCGGCCGTTTTGCCGGGCCATGCTGCGGGAATGGCGTGCCTGGCGTATGAACAGGAAGGAAAAAAG
ACTGGCGCGACAGACCGCTCTGCTTGCCAGGGAAGCTGCCCGCGTGAGGGCCAGCATGGAAGATGCCGCTTTGTCCGCTC
CCAGACCGGTTAGAAAGGGCCGGGCTTCCGTTCCCCGTCTGCAGCGCACCGGGGACGATCTGGAAAGTTTGTATCATGAA
GCAGCGGCGGTTGCTCCGTCCAAGCCGGAGGATTCTGTTCCGCCTCCCAGCGCCCCGCGAACCCAGGGCCGCCTTCCCCT
GGCTCCGCGCCCCAGGATTACCGTTGCGGAACCGGCGGAAATGAAGCCCGCGCCCAAAGAACAGCCTTTTTCCAAATTGT
CCACTCCGCCCACGGAGGAATTCCGCGAGTATGAGCTGCCTCCATTTGAACTGCTGCATTATGAAGAAAAGCCGGAAGGC
CCTACGGCAGAGGACAAGGAAGAAATGCTGGAAATACAGCAGAAGATTATTGATACTCTGACGACATTCCGCGTGGACGT
GACGCCTGGGGATATTACCCGAGGCCCGACCATCACCCGTTATGAAGTGTATCCCGCGCGCGGCGTGCGCGTAAATACTT
TTGACCAGTATGCGAAGGATATTGCGCTGGCGACCAAGGCGGAAAGCGTGAACATCGTGGCCCCCATTCCGGGCAAGGAT
ACGGTAGGTATTGAAATCGTCAACCGGAAGAAGGTGGCCGTTCCCCTGCGGGAACTTTTGCAGGATCCCGCTTTTTGTTC
CCCCAAGAAAAAGATTCCGCTGGCGCTGGGGAAGGACGTGTATGGACGTACCGTGATCGGGGACTTGGCGTCCATGCCGC
ACCTGTTGGTGGCCGGCGCCACCGGATCCGGAAAATCCGTGTGCATTAACAGCATTATTTCCTCCATGCTCCTGAAATTC
CGCCCGGATGAACTGAGGCTTATTCTGGTGGATCCGAAAGTGGTGGAAATGCAGCCTTATTCCAAGCTGCCGCATCTGAT
TGTTCCGGTGGTGACGGATCCCAAGAAAGTTCCCAATGCCCTGCGTTGGTGCGTGAATGAAATGGAGCACCGCTATCATT
GCTTTGCCAAGGTGGGTGTGCGAAACTTTGAAGCTTTCAACAAGCGCCCGCCGGATGTTCCTGCGCAAGAGACGGAGGAA
CCGGAAGACGGGCAGGTGGATGAAGCTTTGGCGGAATCCATTGCCAGAGACCTGGAATCCCAGGGGGAATGGCCTGTGGA
AGAAGATGATGAACTGGATCTGGAGGACGACGGAGTTATTCCTGAACGCTTCCCCTACATCGTCATTATTATTGACGAAC
TTGCGGACCTGATGCAGACAGTAGGAGCGGACATAGAAACGAATATTGGACGTCTTACCCAAAAGGCCCGTGCCGCAGGC
ATCCACCTTATTGTGGCGACGCAGACGCCAAGAAGGCAGGTGGTGACGGGGACGATCAAGGCCAATATCCCGACGCGCAT
CGCTTTCCAGGTGGCGAGCGGTACGGATAGCCGTGTGATTTTGGACAGGCAGGGGGCGGAAAAACTGGTGGGCAAGGGAG
ACCTTCTGTATTTGCCGCCGGGTTCCGCCCAGGTGGAGCGGGCGCAGGGAGCCTTTATCTCTGACGATGAAGTGGAAGCC
CTGGTGGCCCACTGTGCTTCCCAGGCCAAGCAGAAATTCCATGAAGAGGTTCAGAAGTCTCTGGACGAGCCTTCCCGCGG
AGGTGCGGACAGTCCGCTGGATGACGCGGAAGAGGAATGCTATGCCAAGTGCCTGGAAGTGGCTGTTGTGGAACGTAAGG
TAAGCACCTCTCTGCTGCAGCGGCGTTTGAGCATTGGATACGGCCGTGCAGCGCGCATGATGGATTTGCTGGAATCCCGC
GGCATTATTGCCCCGGCGGATAATACCAACCGTCCACGCAAGGTGCTGGTGGAATGA

Upstream 100 bases:

>100_bases
GGGGCGGAGAGTTGCTAGGATAGGAACAGGTATGGCATTGGATATGCAGGAGCATCATGCATTTGAGCATGAAGAGGGGC
GTTCCCCTGTTTGGATTGGA

Downstream 100 bases:

>100_bases
AACGATGAAAAAACTCCCCATGAGACGAATTGTTTCCCTGCCTGTTCTGGCGGCGTTTGTGGTGCTGGGGGCCTCCTGTT
CCCAGCAGGTGCAGCAGCCC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTLGGMAWMLVVLLEWWGLYRLL
HYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQVQGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYA
AGMRPRPFCRAMLREWRAWRMNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHE
AAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEEFREYELPPFELLHYEEKPEG
PTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITRYEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKD
TVGIEIVNRKKVAVPLRELLQDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKF
RPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGVRNFEAFNKRPPDVPAQETEE
PEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVIPERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAG
IHLIVATQTPRRQVVTGTIKANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEA
LVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQRRLSIGYGRAARMMDLLESR
GIIAPADNTNRPRKVLVE

Sequences:

>Translated_818_residues
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTLGGMAWMLVVLLEWWGLYRLL
HYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQVQGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYA
AGMRPRPFCRAMLREWRAWRMNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHE
AAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEEFREYELPPFELLHYEEKPEG
PTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITRYEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKD
TVGIEIVNRKKVAVPLRELLQDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKF
RPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGVRNFEAFNKRPPDVPAQETEE
PEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVIPERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAG
IHLIVATQTPRRQVVTGTIKANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEA
LVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQRRLSIGYGRAARMMDLLESR
GIIAPADNTNRPRKVLVE
>Mature_818_residues
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTLGGMAWMLVVLLEWWGLYRLL
HYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQVQGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYA
AGMRPRPFCRAMLREWRAWRMNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHE
AAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEEFREYELPPFELLHYEEKPEG
PTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITRYEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKD
TVGIEIVNRKKVAVPLRELLQDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKF
RPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGVRNFEAFNKRPPDVPAQETEE
PEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVIPERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAG
IHLIVATQTPRRQVVTGTIKANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEA
LVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQRRLSIGYGRAARMMDLLESR
GIIAPADNTNRPRKVLVE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=41.9753086419753, Blast_Score=358, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89983; Mature: 89983

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTL
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GGMAWMLVVLLEWWGLYRLLHYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYAAGMRPRPFCRAMLREWRAWR
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHCCHHHHHHHHH
AAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCHHH
FREYELPPFELLHYEEKPEGPTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITR
HHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEE
YEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKDTVGIEIVNRKKVAVPLRELL
EEECCCCCCEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHH
QDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKF
CCCCCCCCCCCCCHHHCCCHHCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHC
RPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGV
CCCCEEEEEECCEEEECCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RNFEAFNKRPPDVPAQETEEPEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVI
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAGIHLIVATQTPRRQVVTGTIK
CCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
ANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEA
ECCCCEEEEEEECCCCCEEEEECCCHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHH
LVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSIGYGRAARMMDLLESRGIIAPADNTNRPRKVLVE
HHHHCCCCHHHHHHHHHHHCCCEECCCCCCCCCEECCC
>Mature Secondary Structure
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTL
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GGMAWMLVVLLEWWGLYRLLHYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYAAGMRPRPFCRAMLREWRAWR
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHCCHHHHHHHHH
AAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEE
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCHHH
FREYELPPFELLHYEEKPEGPTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITR
HHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEE
YEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKDTVGIEIVNRKKVAVPLRELL
EEECCCCCCEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHH
QDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKF
CCCCCCCCCCCCCHHHCCCHHCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHC
RPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGV
CCCCEEEEEECCEEEECCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RNFEAFNKRPPDVPAQETEEPEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVI
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAGIHLIVATQTPRRQVVTGTIK
CCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
ANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEA
ECCCCEEEEEEECCCCCEEEEECCCHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHHHHH
LVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSIGYGRAARMMDLLESRGIIAPADNTNRPRKVLVE
HHHHCCCCHHHHHHHHHHHCCCEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]