Click here to switch to the map view.

The map label for this gene is mrdA [H]

Identifier: 187735021

GI number: 187735021

Start: 604239

End: 606707

Strand: Reverse

Name: mrdA [H]

Synonym: Amuc_0514

Alternate gene names: 187735021

Gene position: 606707-604239 (Counterclockwise)

Preceding gene: 187735022

Following gene: 187735020

Centisome position: 22.77

GC content: 60.43

Gene sequence:

>2469_bases
ATGAAAATAAAGGTTCTGATACGTTCCCTGGTATTGTTGGCCGGTTTGGCCGCGTGGACGGCGGATACAGCCTGGGGCCA
GGCTTCCACGCGCCGCCCGTCTTCCCGGGGGGGAGCGGTCGCTGGCCGGGCTGCGGTGGAACAGCGCGGAGAGGATGACG
CCGTGGAAACGGTTGACCTGGGGGACAAAAAGAAGGATTCCGACACGGCTTCCGGCGAACAGGAAGGCGTGGCCGCCGCT
CCGGAGATGCCCAGGGAAACGGAAAAGGAGCAGAATGGCTTGGATTCCCTGTCCCTGATTCCTTCCCTTGGCGGAGGTCG
GCTGGACGCTGCGCGGGAAGCGCACACCAGCACGCGGCCTTCCGCCAGGACCATGGCTCTGCTGATTCCCGCTCCGCGCG
GCCCCATCCTGGACCGCAACGGGGAACCGCTGGCCGTGACTTCCGTAGCCTACCAGCTGGCTTTGCGGTTTGAAATTTTT
GAAAACCCCGACCGTTCCCGCGTGGTGGAATTCGGGCGCAACTGTTTGGAACAGGCCAAAAAAATTGCCGGAAAGGCGTG
GTCTTTTTCCGACGAACAGCTCTGGAAACATTATGAGCACCGCCGCTGGCTGCCTCTTCCGCTCACGAACGTCATTCGTG
CGGAGGAAGCGGAAAAGCTGAAGGATAAGGTGAAAAGTGTGCGCGGCCTCCAGCTGCTGCCCATTTACATCCGTTCCTAT
CCGGAGAAGGAAATCGCCGGCCATATCATCGGCTATGTGGGGTCCAAGGGAAAACTGCCAACCGGCCCCATCAACCACAT
GGATCCGCTTTGGGAGCAGGTGGAAGGCCGTGCGGGGCTGGAAAAGGAATTCAACAAAAATCTGACCGGAACGCCCGGCG
TATGGCGCTTGATGTTTGACGAAGACGGCAATAAAATTCTGGATGAACTGCAAATACGCCCCAAGCCCGGCGGGGCTGTC
GTCACCACCCTCAACCTGAAATGGCAGAAGGATGCGGAACGCATCCTTTCCCGCGGCAAGAGGCGCGGCGCCATGGTGGT
GCTGGACTGCGTGACGGGTGAAGTTCTGGTGATGGCGTCCACGCCGTCCTATGACCCGAACATGTTCATTCCAAACATAT
CCCAGAAAGATTACGATGCTTTGCGCAATGATCCTGCCGGTCCTCTGGGCGCCCGTGCTTTCCAGGGCCGTTATCCCCCC
GCTTCCACATTTAAAGTCCTGACGGTAGCCAGTGCCTTGAGGAACAACAAAATCACGGAAAATACGCTCGTTTACTGCCC
GGCTTCCGTGACGATCGGCAACCACGTGTTCAAAAACTGGAGCAAGACTCCCCTGGGGGATATCAACTGTGTCCGCGCCC
TGGCGATGTCCAATAATCCGTTCATGTACCAGATGGGCCTGAAGCTGGGTGCGGAAGCCCTGATGGATACGGCCCGCGCC
TTCGGCCTGGGGGAACGGACCGGCCTGCCCATTCCGGACGATCCCGGCCTGGTGCCGACCAGTGATTATATGATCCGCAA
TTACAAGCGCGATTTCATGTCCGGGGATGCCGCCAATTTGTCCATCGGCCAGGGGACGTTGCTGGTTACGCCCCTCCAGG
TGGCGCACATGATGTCCGGCGTGGCAAACGGGTATCTGCCCAGGCTCCAGCTCATCAAGCAGATTCAGGACGGCAACGCC
AATGTCGTTTACGCGCCCAAGCCCCAGGAAGTTCAACGTCCTCTGCCTGCCTATGAGCGTGCTCTGTCCAGCGTGCGCAA
GGGGATGAGGGAAGTGGTTGAAGCCGGTACGGGGGGGCGTGCACGCCTGTCTTATGCCAGTATCGCCGGCAAATCCGGAA
CGGCCCAATGGGGGCCGGAACGGGAAGACAAGCGTCTGGCGTGGTTCGCCGGTTTCATGCCCTGCGACAATCCGCGCTTT
GCCTATGTGGTGCTGTATGAAGGCCGCGCCCACGAACGGCTGGGCGGGGGGGCTGCCGCCGCTCCCATCGTAAAGGAATT
TTTCGAAACGGAGAAAAAAGACATCAAGGCTATTATTGACCCGCCCAAAGATGACATCCCGGTGGCGGAACCGGTGGAGG
AGACCCCGGAAACGGCCGCGGCCGCTCTTCGGGAACGGAGCGGAGCGCCTGCCGTCGTGCCGGACAACCTGCCGCCCGGC
TTGTATGATCCGGAAGGGATGGAGCCGATCAAGGCTGATGAAATCCCTGCCGATCTGGATGACTCTTCCGATGCTGAAAT
CAAGGCAACTCCGGTGGGCGGCTCCTCAAGGCCTGCCGGGCCGTCGGCGCCTCCGTTGTCGGAGGAGCCTTCTGCGGCCC
CCCTCACGCCGCGCCGGGGTGATTCCGATTACATCCCCGGACTGCCCCAGCAGATTCCCCGCCATCTTAACCGTTCCACC
TCCGTAAACACTCCTGCGCCGCAGTCTCCCCTGCCGGAGGATGATATTCCCATGGCGGAACCTCTTTAA

Upstream 100 bases:

>100_bases
ACAAATGCGGCCTGGGAACAACCGTCATCGTTCAGGAATAAGCGTGAGCGTGAATAATCGTTGATTCCTTGCGGTATATT
TGCCACAATCCTGCAAGCTG

Downstream 100 bases:

>100_bases
TCCGGTTCTTAGAGAAAGCCGGAGAGTTTTTGCGGTTTCCGGAACGGCTTTTTCCCGGACAATATTGGCGGGGGAAAAAG
GAAAATCTGGCGGATACGGG

Product: Peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MKIKVLIRSLVLLAGLAAWTADTAWGQASTRRPSSRGGAVAGRAAVEQRGEDDAVETVDLGDKKKDSDTASGEQEGVAAA
PEMPRETEKEQNGLDSLSLIPSLGGGRLDAAREAHTSTRPSARTMALLIPAPRGPILDRNGEPLAVTSVAYQLALRFEIF
ENPDRSRVVEFGRNCLEQAKKIAGKAWSFSDEQLWKHYEHRRWLPLPLTNVIRAEEAEKLKDKVKSVRGLQLLPIYIRSY
PEKEIAGHIIGYVGSKGKLPTGPINHMDPLWEQVEGRAGLEKEFNKNLTGTPGVWRLMFDEDGNKILDELQIRPKPGGAV
VTTLNLKWQKDAERILSRGKRRGAMVVLDCVTGEVLVMASTPSYDPNMFIPNISQKDYDALRNDPAGPLGARAFQGRYPP
ASTFKVLTVASALRNNKITENTLVYCPASVTIGNHVFKNWSKTPLGDINCVRALAMSNNPFMYQMGLKLGAEALMDTARA
FGLGERTGLPIPDDPGLVPTSDYMIRNYKRDFMSGDAANLSIGQGTLLVTPLQVAHMMSGVANGYLPRLQLIKQIQDGNA
NVVYAPKPQEVQRPLPAYERALSSVRKGMREVVEAGTGGRARLSYASIAGKSGTAQWGPEREDKRLAWFAGFMPCDNPRF
AYVVLYEGRAHERLGGGAAAAPIVKEFFETEKKDIKAIIDPPKDDIPVAEPVEETPETAAAALRERSGAPAVVPDNLPPG
LYDPEGMEPIKADEIPADLDDSSDAEIKATPVGGSSRPAGPSAPPLSEEPSAAPLTPRRGDSDYIPGLPQQIPRHLNRST
SVNTPAPQSPLPEDDIPMAEPL

Sequences:

>Translated_822_residues
MKIKVLIRSLVLLAGLAAWTADTAWGQASTRRPSSRGGAVAGRAAVEQRGEDDAVETVDLGDKKKDSDTASGEQEGVAAA
PEMPRETEKEQNGLDSLSLIPSLGGGRLDAAREAHTSTRPSARTMALLIPAPRGPILDRNGEPLAVTSVAYQLALRFEIF
ENPDRSRVVEFGRNCLEQAKKIAGKAWSFSDEQLWKHYEHRRWLPLPLTNVIRAEEAEKLKDKVKSVRGLQLLPIYIRSY
PEKEIAGHIIGYVGSKGKLPTGPINHMDPLWEQVEGRAGLEKEFNKNLTGTPGVWRLMFDEDGNKILDELQIRPKPGGAV
VTTLNLKWQKDAERILSRGKRRGAMVVLDCVTGEVLVMASTPSYDPNMFIPNISQKDYDALRNDPAGPLGARAFQGRYPP
ASTFKVLTVASALRNNKITENTLVYCPASVTIGNHVFKNWSKTPLGDINCVRALAMSNNPFMYQMGLKLGAEALMDTARA
FGLGERTGLPIPDDPGLVPTSDYMIRNYKRDFMSGDAANLSIGQGTLLVTPLQVAHMMSGVANGYLPRLQLIKQIQDGNA
NVVYAPKPQEVQRPLPAYERALSSVRKGMREVVEAGTGGRARLSYASIAGKSGTAQWGPEREDKRLAWFAGFMPCDNPRF
AYVVLYEGRAHERLGGGAAAAPIVKEFFETEKKDIKAIIDPPKDDIPVAEPVEETPETAAAALRERSGAPAVVPDNLPPG
LYDPEGMEPIKADEIPADLDDSSDAEIKATPVGGSSRPAGPSAPPLSEEPSAAPLTPRRGDSDYIPGLPQQIPRHLNRST
SVNTPAPQSPLPEDDIPMAEPL
>Mature_822_residues
MKIKVLIRSLVLLAGLAAWTADTAWGQASTRRPSSRGGAVAGRAAVEQRGEDDAVETVDLGDKKKDSDTASGEQEGVAAA
PEMPRETEKEQNGLDSLSLIPSLGGGRLDAAREAHTSTRPSARTMALLIPAPRGPILDRNGEPLAVTSVAYQLALRFEIF
ENPDRSRVVEFGRNCLEQAKKIAGKAWSFSDEQLWKHYEHRRWLPLPLTNVIRAEEAEKLKDKVKSVRGLQLLPIYIRSY
PEKEIAGHIIGYVGSKGKLPTGPINHMDPLWEQVEGRAGLEKEFNKNLTGTPGVWRLMFDEDGNKILDELQIRPKPGGAV
VTTLNLKWQKDAERILSRGKRRGAMVVLDCVTGEVLVMASTPSYDPNMFIPNISQKDYDALRNDPAGPLGARAFQGRYPP
ASTFKVLTVASALRNNKITENTLVYCPASVTIGNHVFKNWSKTPLGDINCVRALAMSNNPFMYQMGLKLGAEALMDTARA
FGLGERTGLPIPDDPGLVPTSDYMIRNYKRDFMSGDAANLSIGQGTLLVTPLQVAHMMSGVANGYLPRLQLIKQIQDGNA
NVVYAPKPQEVQRPLPAYERALSSVRKGMREVVEAGTGGRARLSYASIAGKSGTAQWGPEREDKRLAWFAGFMPCDNPRF
AYVVLYEGRAHERLGGGAAAAPIVKEFFETEKKDIKAIIDPPKDDIPVAEPVEETPETAAAALRERSGAPAVVPDNLPPG
LYDPEGMEPIKADEIPADLDDSSDAEIKATPVGGSSRPAGPSAPPLSEEPSAAPLTPRRGDSDYIPGLPQQIPRHLNRST
SVNTPAPQSPLPEDDIPMAEPL

Specific function: Cell wall formation; PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=589, Percent_Identity=28.5229202037351, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1786272, Length=456, Percent_Identity=28.9473684210526, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR017790 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 89282; Mature: 89282

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKVLIRSLVLLAGLAAWTADTAWGQASTRRPSSRGGAVAGRAAVEQRGEDDAVETVDL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECC
GDKKKDSDTASGEQEGVAAAPEMPRETEKEQNGLDSLSLIPSLGGGRLDAAREAHTSTRP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHCCCCC
SARTMALLIPAPRGPILDRNGEPLAVTSVAYQLALRFEIFENPDRSRVVEFGRNCLEQAK
CCCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KIAGKAWSFSDEQLWKHYEHRRWLPLPLTNVIRAEEAEKLKDKVKSVRGLQLLPIYIRSY
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCC
PEKEIAGHIIGYVGSKGKLPTGPINHMDPLWEQVEGRAGLEKEFNKNLTGTPGVWRLMFD
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEE
EDGNKILDELQIRPKPGGAVVTTLNLKWQKDAERILSRGKRRGAMVVLDCVTGEVLVMAS
CCCHHHHHHCEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEC
TPSYDPNMFIPNISQKDYDALRNDPAGPLGARAFQGRYPPASTFKVLTVASALRNNKITE
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
NTLVYCPASVTIGNHVFKNWSKTPLGDINCVRALAMSNNPFMYQMGLKLGAEALMDTARA
CEEEEECCCEECCHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FGLGERTGLPIPDDPGLVPTSDYMIRNYKRDFMSGDAANLSIGQGTLLVTPLQVAHMMSG
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHH
VANGYLPRLQLIKQIQDGNANVVYAPKPQEVQRPLPAYERALSSVRKGMREVVEAGTGGR
HHCCCHHHHHHHHHHHCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
ARLSYASIAGKSGTAQWGPEREDKRLAWFAGFMPCDNPRFAYVVLYEGRAHERLGGGAAA
EEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHCCCCHHH
APIVKEFFETEKKDIKAIIDPPKDDIPVAEPVEETPETAAAALRERSGAPAVVPDNLPPG
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LYDPEGMEPIKADEIPADLDDSSDAEIKATPVGGSSRPAGPSAPPLSEEPSAAPLTPRRG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DSDYIPGLPQQIPRHLNRSTSVNTPAPQSPLPEDDIPMAEPL
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIKVLIRSLVLLAGLAAWTADTAWGQASTRRPSSRGGAVAGRAAVEQRGEDDAVETVDL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECC
GDKKKDSDTASGEQEGVAAAPEMPRETEKEQNGLDSLSLIPSLGGGRLDAAREAHTSTRP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHCCCCC
SARTMALLIPAPRGPILDRNGEPLAVTSVAYQLALRFEIFENPDRSRVVEFGRNCLEQAK
CCCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KIAGKAWSFSDEQLWKHYEHRRWLPLPLTNVIRAEEAEKLKDKVKSVRGLQLLPIYIRSY
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCC
PEKEIAGHIIGYVGSKGKLPTGPINHMDPLWEQVEGRAGLEKEFNKNLTGTPGVWRLMFD
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEEEEEE
EDGNKILDELQIRPKPGGAVVTTLNLKWQKDAERILSRGKRRGAMVVLDCVTGEVLVMAS
CCCHHHHHHCEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEC
TPSYDPNMFIPNISQKDYDALRNDPAGPLGARAFQGRYPPASTFKVLTVASALRNNKITE
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
NTLVYCPASVTIGNHVFKNWSKTPLGDINCVRALAMSNNPFMYQMGLKLGAEALMDTARA
CEEEEECCCEECCHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FGLGERTGLPIPDDPGLVPTSDYMIRNYKRDFMSGDAANLSIGQGTLLVTPLQVAHMMSG
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHH
VANGYLPRLQLIKQIQDGNANVVYAPKPQEVQRPLPAYERALSSVRKGMREVVEAGTGGR
HHCCCHHHHHHHHHHHCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
ARLSYASIAGKSGTAQWGPEREDKRLAWFAGFMPCDNPRFAYVVLYEGRAHERLGGGAAA
EEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHCCCCHHH
APIVKEFFETEKKDIKAIIDPPKDDIPVAEPVEETPETAAAALRERSGAPAVVPDNLPPG
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LYDPEGMEPIKADEIPADLDDSSDAEIKATPVGGSSRPAGPSAPPLSEEPSAAPLTPRRG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DSDYIPGLPQQIPRHLNRSTSVNTPAPQSPLPEDDIPMAEPL
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]