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The map label for this gene is ribH [H]

Identifier: 187734930

GI number: 187734930

Start: 507054

End: 507542

Strand: Direct

Name: ribH [H]

Synonym: Amuc_0423

Alternate gene names: 187734930

Gene position: 507054-507542 (Clockwise)

Preceding gene: 187734929

Following gene: 187734931

Centisome position: 19.03

GC content: 60.53

Gene sequence:

>489_bases
ATGTCCACGGAACTTCCCCGCCGCCAGCGCGCCACGGGCACGCGCGCCAAAATCTGCATCGTCGCCTCGGAATACAACGA
ACAATACACCCAGGCCCTGGTAGAAAACTGCTCGGAAGAACTGAAAACCGTGCTTCCCTCGGTCCGCCTGGAAATCATCC
GCGTGCCGGGAGCCTTTGAAATTCCGGTGGCCATTAAATCCGTTCTCTCCCGCTCTCCGGAAAAACGTCCTGATGCCGTG
GTGGCTCTGGGGGTCATCCTGCGCGGCAGCACAGACCACGCGGACCTTATCGGCTCCACCATTACCCAGGCCCTGATGCA
GCTCGCCCTGGAATTCACCACCCCCGTCATTCATGAAGTTCTGCTGCTGAATGATGAAAAGCAGGCCTTCGCCCGCTGTA
TCGCCTCTCAGCTCAACCGCGGCCGTGAAGCGGCCCGCACCGCTGCCCGCATGGCGGAACTCTTCCTCAACTCCCTGCTC
CGGCAATAA

Upstream 100 bases:

>100_bases
GTTCCTCTCATCATCCCACCCAACGAACAAAACAGCAAATACCTGGCTACCAAAAAATGCAAGCTGGGCCACATCCTGTA
ACATTCCACTCCATCCCTTC

Downstream 100 bases:

>100_bases
TACCTATTACTCTCTCCTCTCTATCGCCATGCTCTCACGCAACCAAATCAGACAAGCCGCCCTCCAATACCTTTACGCCG
CCTCTCAGACGCCGGAAACG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSTELPRRQRATGTRAKICIVASEYNEQYTQALVENCSEELKTVLPSVRLEIIRVPGAFEIPVAIKSVLSRSPEKRPDAV
VALGVILRGSTDHADLIGSTITQALMQLALEFTTPVIHEVLLLNDEKQAFARCIASQLNRGREAARTAARMAELFLNSLL
RQ

Sequences:

>Translated_162_residues
MSTELPRRQRATGTRAKICIVASEYNEQYTQALVENCSEELKTVLPSVRLEIIRVPGAFEIPVAIKSVLSRSPEKRPDAV
VALGVILRGSTDHADLIGSTITQALMQLALEFTTPVIHEVLLLNDEKQAFARCIASQLNRGREAARTAARMAELFLNSLL
RQ
>Mature_161_residues
STELPRRQRATGTRAKICIVASEYNEQYTQALVENCSEELKTVLPSVRLEIIRVPGAFEIPVAIKSVLSRSPEKRPDAVV
ALGVILRGSTDHADLIGSTITQALMQLALEFTTPVIHEVLLLNDEKQAFARCIASQLNRGREAARTAARMAELFLNSLLR
Q

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=138, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324429, Length=154, Percent_Identity=30.5194805194805, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17898; Mature: 17767

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTELPRRQRATGTRAKICIVASEYNEQYTQALVENCSEELKTVLPSVRLEIIRVPGAFE
CCCCCCCHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
IPVAIKSVLSRSPEKRPDAVVALGVILRGSTDHADLIGSTITQALMQLALEFTTPVIHEV
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLNDEKQAFARCIASQLNRGREAARTAARMAELFLNSLLRQ
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STELPRRQRATGTRAKICIVASEYNEQYTQALVENCSEELKTVLPSVRLEIIRVPGAFE
CCCCCCHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
IPVAIKSVLSRSPEKRPDAVVALGVILRGSTDHADLIGSTITQALMQLALEFTTPVIHEV
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLNDEKQAFARCIASQLNRGREAARTAARMAELFLNSLLRQ
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA