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The map label for this gene is nahA [H]

Identifier: 187734905

GI number: 187734905

Start: 479336

End: 481504

Strand: Reverse

Name: nahA [H]

Synonym: Amuc_0397

Alternate gene names: 187734905

Gene position: 481504-479336 (Counterclockwise)

Preceding gene: 187734906

Following gene: 187734903

Centisome position: 18.07

GC content: 55.74

Gene sequence:

>2169_bases
ATGCTTTTGTTCAGAGTGTTCAGCATTCCCGTACGGTTTTTTATTGCCTTGCTGATTTATTTTTCATGGGGGCCGCTGGC
CGGAGGGGTGGTTACCGCGCCTGTGCCGGAGTTTTCTTCCCCCGCGCTTATTCCATATCCTTCCAAAGTCGTCAGGGGCG
CGGGCGAGGCAGGTTTCAGGAGCGTTCATGTGAAGGTTGGTTCGGATGTTCCTGGCAGGGATGATTTGATGAAGGAGATC
AAGGACATATTCAGGACTTCCGGCATTCAGGGTTCCCTGAATAGTGGGGGGGCTGCTGAAGGTGCCATGACATGGGAATT
GTTTCCGGACGCCAGGATGAAAGGAGAGGGGTATGACCTGTCCGTCGGATTGGGAAAAGCAACCGTCAGGGCAGGAAGTT
TTGGCGGTTTTTTTAACGCTCTTCAAACGCTGCGGCAACTGGTTTTCAATAGAGAAGGGGAATTTGCCATGCCTGTTGTG
CGTATTAGTGACAAACCCGCTTTCGTCCTGCGGGGAATTATGCTGGATGTGGGGCGTTATTACATGTCTCCTGCCTTGAT
CAAGGAGGTGATGCGCCGTCTTTCCCGCTATAAGATTAATACGCTGCATCTTCATTTGACGGATGATCCCGCATGGAGGC
TGGAAGTGAAGAAGTATCCGGCCCTGACGGATGGGGCTTTTCATTGGAAGTCCCGGCTCCCGGGGCGGTTTTATACACAG
GCTCAATTGAAGGATCTGACGGATTATTGCGCCCGGTTGAATATCCAGGTGATTCCGGAGATTGACATGCCGGGACACAG
CCAGCCTTTTGCCAGGGCCATGAAGACCGGCATGCAGACGGAGAAGGGTGTTTCCATATTGAAGGATGTCGTGGACGAGG
CCGTTTCCCTGTTTCCCGGGAGGTTTTTCCACATGGGATCCGACGAGGCGCACATTTCCATGAAGGATTTTATCCCACGT
ATGGCGGAGCATATCCGCGGGAAGGGCAAGGAGGTGGTCGTGTGGTCTCCGGGCGGCCCGCACGATAAGGATTCCGTATT
GATGTGCTGGGGAGAGAACGAGGCCGGCGCCAGGATGGATAAGAATATGAAGCGCATCGACAGCAATGGTTTTTACATTG
ACTGGGCGGATTCCCAGTCCGGCGTGTACCAGGTGTTTTTCCAGCAGCCCTGCGAGGTGCCTCAAGGGGATGATAAGGCG
TTGGGGGCCATCATGCCCGTGTGGTGCGACGGAAACCTGAGCAGTGAGAGGCGGGTGCTGGAACAGTATCCGTTTTATCC
TTGTGCATTGACGTTTGCAGAGCGTGTCTGGCGCGGAAGCGCTACCAAGAGGAGGGATTATATGGCCCAGCTTCCCCCCA
GGGGAACGGACGGCTGGAAGGAATTCCGGGAGTTTGAACAGCGTTTGGCTTTCCATCGTGATCATTTTTTCCAAGGCGTT
CCTTTTGCCTATGTGAAACAGGCGGACGTTGCCTGGAGCCTGGTGGGGCCATTCGACCACCGGGGGAAGAATGATACCTC
TTTTGAACCGGAAAGAAGAATAGCCCCTTCCTACAGGGACGGGGACAGGATACTGGCCTGGAAGAAGACTCCTGTTTACG
GCGCCGCCGTACATGTCAGGCATCTTTTTGCGATGTTCAACATGCACCGGAACCAGTACCGGACGGACCACTGGCCCACG
CTGATGTCAAGGGAGGTTGGAAAGGAGGATGGAACCTGCTATGCTCTGACTTTCATCCGCAGCCCCAGGGAGCAGGAGGT
GTGGCTGATGTTTGGCCTGAACGGCATGTGGGGGCATTCAGGCGGGTACCGCAGCGCACGCGCCCCTGAACAGGGAAGCT
GGGATTTTTCCGGCGGGGACGTATGGTTGAACGGAAGGCGCGTGAACCCTCCCAGGTGGCCTTTCAAGAGCCTGCCCTGG
ACGGGGTGGGGAAAGGGGCGCATTGAAGAAGCTCCTCTGACCTGGGAAGGGTATTTTTTCCGCCCTCCTGTAAAGATCAA
GCTCCGCAAGGGGTTGAACCGTGTATTGATCCGCAGCGTGTTCGGGCACTGGAAGGGAGACGACGGCCAGAGAAGCTGGT
TTTTCTGCTGCATTCCCGTCCTGTGGGACGGCATTCATTACCGGGAGGTTCCCGGCCTGGAATATGACCCCCGTCCGGAT
GCCCGCTGA

Upstream 100 bases:

>100_bases
TAAGCATGTCGGTGTTGGAGAGGATGGGAAAAGCATTTGGTTTCCCAGTTGAGAAAGCCCTGTTTTGACAGGAGCGGAGA
TGGAATGCCGTAGTTAAGGA

Downstream 100 bases:

>100_bases
GGGGAACCGCTATTATTCTTTTTCAAAGACGGAGAGGATGGCTTGATGGACATCCTCAGCAGCATGGATTTCCGGCAGGA
AGGCCGGGCCGATGAATACG

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MLLFRVFSIPVRFFIALLIYFSWGPLAGGVVTAPVPEFSSPALIPYPSKVVRGAGEAGFRSVHVKVGSDVPGRDDLMKEI
KDIFRTSGIQGSLNSGGAAEGAMTWELFPDARMKGEGYDLSVGLGKATVRAGSFGGFFNALQTLRQLVFNREGEFAMPVV
RISDKPAFVLRGIMLDVGRYYMSPALIKEVMRRLSRYKINTLHLHLTDDPAWRLEVKKYPALTDGAFHWKSRLPGRFYTQ
AQLKDLTDYCARLNIQVIPEIDMPGHSQPFARAMKTGMQTEKGVSILKDVVDEAVSLFPGRFFHMGSDEAHISMKDFIPR
MAEHIRGKGKEVVVWSPGGPHDKDSVLMCWGENEAGARMDKNMKRIDSNGFYIDWADSQSGVYQVFFQQPCEVPQGDDKA
LGAIMPVWCDGNLSSERRVLEQYPFYPCALTFAERVWRGSATKRRDYMAQLPPRGTDGWKEFREFEQRLAFHRDHFFQGV
PFAYVKQADVAWSLVGPFDHRGKNDTSFEPERRIAPSYRDGDRILAWKKTPVYGAAVHVRHLFAMFNMHRNQYRTDHWPT
LMSREVGKEDGTCYALTFIRSPREQEVWLMFGLNGMWGHSGGYRSARAPEQGSWDFSGGDVWLNGRRVNPPRWPFKSLPW
TGWGKGRIEEAPLTWEGYFFRPPVKIKLRKGLNRVLIRSVFGHWKGDDGQRSWFFCCIPVLWDGIHYREVPGLEYDPRPD
AR

Sequences:

>Translated_722_residues
MLLFRVFSIPVRFFIALLIYFSWGPLAGGVVTAPVPEFSSPALIPYPSKVVRGAGEAGFRSVHVKVGSDVPGRDDLMKEI
KDIFRTSGIQGSLNSGGAAEGAMTWELFPDARMKGEGYDLSVGLGKATVRAGSFGGFFNALQTLRQLVFNREGEFAMPVV
RISDKPAFVLRGIMLDVGRYYMSPALIKEVMRRLSRYKINTLHLHLTDDPAWRLEVKKYPALTDGAFHWKSRLPGRFYTQ
AQLKDLTDYCARLNIQVIPEIDMPGHSQPFARAMKTGMQTEKGVSILKDVVDEAVSLFPGRFFHMGSDEAHISMKDFIPR
MAEHIRGKGKEVVVWSPGGPHDKDSVLMCWGENEAGARMDKNMKRIDSNGFYIDWADSQSGVYQVFFQQPCEVPQGDDKA
LGAIMPVWCDGNLSSERRVLEQYPFYPCALTFAERVWRGSATKRRDYMAQLPPRGTDGWKEFREFEQRLAFHRDHFFQGV
PFAYVKQADVAWSLVGPFDHRGKNDTSFEPERRIAPSYRDGDRILAWKKTPVYGAAVHVRHLFAMFNMHRNQYRTDHWPT
LMSREVGKEDGTCYALTFIRSPREQEVWLMFGLNGMWGHSGGYRSARAPEQGSWDFSGGDVWLNGRRVNPPRWPFKSLPW
TGWGKGRIEEAPLTWEGYFFRPPVKIKLRKGLNRVLIRSVFGHWKGDDGQRSWFFCCIPVLWDGIHYREVPGLEYDPRPD
AR
>Mature_722_residues
MLLFRVFSIPVRFFIALLIYFSWGPLAGGVVTAPVPEFSSPALIPYPSKVVRGAGEAGFRSVHVKVGSDVPGRDDLMKEI
KDIFRTSGIQGSLNSGGAAEGAMTWELFPDARMKGEGYDLSVGLGKATVRAGSFGGFFNALQTLRQLVFNREGEFAMPVV
RISDKPAFVLRGIMLDVGRYYMSPALIKEVMRRLSRYKINTLHLHLTDDPAWRLEVKKYPALTDGAFHWKSRLPGRFYTQ
AQLKDLTDYCARLNIQVIPEIDMPGHSQPFARAMKTGMQTEKGVSILKDVVDEAVSLFPGRFFHMGSDEAHISMKDFIPR
MAEHIRGKGKEVVVWSPGGPHDKDSVLMCWGENEAGARMDKNMKRIDSNGFYIDWADSQSGVYQVFFQQPCEVPQGDDKA
LGAIMPVWCDGNLSSERRVLEQYPFYPCALTFAERVWRGSATKRRDYMAQLPPRGTDGWKEFREFEQRLAFHRDHFFQGV
PFAYVKQADVAWSLVGPFDHRGKNDTSFEPERRIAPSYRDGDRILAWKKTPVYGAAVHVRHLFAMFNMHRNQYRTDHWPT
LMSREVGKEDGTCYALTFIRSPREQEVWLMFGLNGMWGHSGGYRSARAPEQGSWDFSGGDVWLNGRRVNPPRWPFKSLPW
TGWGKGRIEEAPLTWEGYFFRPPVKIKLRKGLNRVLIRSVFGHWKGDDGQRSWFFCCIPVLWDGIHYREVPGLEYDPRPD
AR

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=241, Percent_Identity=26.1410788381743, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI189181666, Length=234, Percent_Identity=25.6410256410256, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17569815, Length=298, Percent_Identity=28.1879194630872, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24657468, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647501, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281365639, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24657474, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653074, Length=158, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45551090, Length=158, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 82360; Mature: 82360

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFRVFSIPVRFFIALLIYFSWGPLAGGVVTAPVPEFSSPALIPYPSKVVRGAGEAGFR
CEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCCCCE
SVHVKVGSDVPGRDDLMKEIKDIFRTSGIQGSLNSGGAAEGAMTWELFPDARMKGEGYDL
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEE
SVGLGKATVRAGSFGGFFNALQTLRQLVFNREGEFAMPVVRISDKPAFVLRGIMLDVGRY
EEECCCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
YMSPALIKEVMRRLSRYKINTLHLHLTDDPAWRLEVKKYPALTDGAFHWKSRLPGRFYTQ
HCCHHHHHHHHHHHHHCEEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEHH
AQLKDLTDYCARLNIQVIPEIDMPGHSQPFARAMKTGMQTEKGVSILKDVVDEAVSLFPG
HHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RFFHMGSDEAHISMKDFIPRMAEHIRGKGKEVVVWSPGGPHDKDSVLMCWGENEAGARMD
CEEECCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHH
KNMKRIDSNGFYIDWADSQSGVYQVFFQQPCEVPQGDDKALGAIMPVWCDGNLSSERRVL
HHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
EQYPFYPCALTFAERVWRGSATKRRDYMAQLPPRGTDGWKEFREFEQRLAFHRDHFFQGV
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFAYVKQADVAWSLVGPFDHRGKNDTSFEPERRIAPSYRDGDRILAWKKTPVYGAAVHVR
CHHHEECCCCEEEEECCHHCCCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCHHHHHHH
HLFAMFNMHRNQYRTDHWPTLMSREVGKEDGTCYALTFIRSPREQEVWLMFGLNGMWGHS
HHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC
GGYRSARAPEQGSWDFSGGDVWLNGRRVNPPRWPFKSLPWTGWGKGRIEEAPLTWEGYFF
CCCCCCCCCCCCCCCCCCCCEEECCEECCCCCCCCCCCCCCCCCCCCEECCCEEECCEEE
RPPVKIKLRKGLNRVLIRSVFGHWKGDDGQRSWFFCCIPVLWDGIHYREVPGLEYDPRPD
CCCCEEHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCEECCCCCCCCCCCC
AR
CC
>Mature Secondary Structure
MLLFRVFSIPVRFFIALLIYFSWGPLAGGVVTAPVPEFSSPALIPYPSKVVRGAGEAGFR
CEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCCCCE
SVHVKVGSDVPGRDDLMKEIKDIFRTSGIQGSLNSGGAAEGAMTWELFPDARMKGEGYDL
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEE
SVGLGKATVRAGSFGGFFNALQTLRQLVFNREGEFAMPVVRISDKPAFVLRGIMLDVGRY
EEECCCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
YMSPALIKEVMRRLSRYKINTLHLHLTDDPAWRLEVKKYPALTDGAFHWKSRLPGRFYTQ
HCCHHHHHHHHHHHHHCEEEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEHH
AQLKDLTDYCARLNIQVIPEIDMPGHSQPFARAMKTGMQTEKGVSILKDVVDEAVSLFPG
HHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RFFHMGSDEAHISMKDFIPRMAEHIRGKGKEVVVWSPGGPHDKDSVLMCWGENEAGARMD
CEEECCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHH
KNMKRIDSNGFYIDWADSQSGVYQVFFQQPCEVPQGDDKALGAIMPVWCDGNLSSERRVL
HHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
EQYPFYPCALTFAERVWRGSATKRRDYMAQLPPRGTDGWKEFREFEQRLAFHRDHFFQGV
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFAYVKQADVAWSLVGPFDHRGKNDTSFEPERRIAPSYRDGDRILAWKKTPVYGAAVHVR
CHHHEECCCCEEEEECCHHCCCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCHHHHHHH
HLFAMFNMHRNQYRTDHWPTLMSREVGKEDGTCYALTFIRSPREQEVWLMFGLNGMWGHS
HHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC
GGYRSARAPEQGSWDFSGGDVWLNGRRVNPPRWPFKSLPWTGWGKGRIEEAPLTWEGYFF
CCCCCCCCCCCCCCCCCCCCEEECCEECCCCCCCCCCCCCCCCCCCCEECCCEEECCEEE
RPPVKIKLRKGLNRVLIRSVFGHWKGDDGQRSWFFCCIPVLWDGIHYREVPGLEYDPRPD
CCCCEEHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCEECCCCCCCCCCCC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]