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The map label for this gene is yjbC [C]

Identifier: 187734754

GI number: 187734754

Start: 299641

End: 301044

Strand: Reverse

Name: yjbC [C]

Synonym: Amuc_0242

Alternate gene names: 187734754

Gene position: 301044-299641 (Counterclockwise)

Preceding gene: 187734755

Following gene: 187734753

Centisome position: 11.3

GC content: 57.12

Gene sequence:

>1404_bases
ATGAGTGAAGAACAACATGGCTCCGAAGAAAACGGAGGTATCCGCATTAATAAATTCCTGGCTTCCTGCGGCATTGACTC
CCGCCGGGTGGCCGACAGGCTGATTGGGGAAGGACGTGTGGAAGTGAACGGGAAGGTTATCGATACGCCTGGGATGAGGG
TGACGGAGAAGGATTTCGTGAAGGTGGACGGCCGCCATATGACCCCTATGGAAGAGGTTGTGGTGCTGTTGAACAAGCCC
CGCGGGTATGTGTGCAGCCGCGAAGCGCAGGGAGCCATAGGTACTGTTTACGACCTGCTGCCGCCGCGCCTGCGCCATCT
GAATTATGTGGGACGGCTGGATGCCGATTCCGAAGGTCTTCTGATTATGACGAATAAGGGGGAATTGACCCAGGTTCTTT
CCCATCCTACCGGCGGCATAGAAAAGGAGTACTGGGTGACGGTAGATCAGAATTTTGATAATTCCGTACTGATGCAGTTT
TTGCGCGGAGTACGCATTCCGGAGGGAAATGCCAAGGCCAAATATGTTTGCCGCGCTTCCGCGCGCCGTGCCTGCATTGT
TTTGGAACAGGGGTTGAAGCGTCAGGTGCGTCAAATGTTCCAGTGCCTGGGCCTTCGTGTCCGCAAGTTGGTGCGCGTGC
GCATCGGCTCCCTGTGGGGAGGGGACTTGGAACCCGGGGGCTGGAAATTCCTGGATGATGCGGACGTGGCTCTGTCACTG
AAAAATCCTCCCCGCCAGCGTAAATACCTGGGTGCTTCCCAGCTTGTCGCCGGGGGGGGCGCCAAGGGTGAGCAGGGCGG
AAGAGGCGTTGATTCCGATGAGGATTATGTGTTTAATCCGGAAGATTTTGAAGCTGGCGATTCTTATGAACCTACTCCGG
AAATGAAGACTCGTTTTGTGGAGACGGAGGATGAACGTGAAGTCAAGGAAGATGGATATTTCCGGGGAGATTCCGGCTTC
CGTTCCCGTGACCGCCGCGGAGATTTTCATCGTCGTGGAGATGGCTTCCGCGGCCGCCGCGGGGATGGGGCCCTGCGCCG
CGAGGCCGGTTTCAAAGAAGAGCGACGTAAAGGAGGGTTCCAACGCCGTGAAGGCGGCTTTGGAAGAGACCGCCGCGAAG
GAGGTTTTCAGCATCAGGAGGGAGGTTTCAGGGAAAACCGTCGTGAAGGAGGATTCCAACGCCGTGAAGGCGGTTTTGGG
AGAGACCGCCGCGAAGGAGGTTTCCAGCATCAGGAGAGAGGTTTCAGGGAAAACCGTCGTGAAGGAGGGTTCCAACGCCG
TGAAGGCGGTTTTGGGAGAGACCGCCGCGGAGGAGGTTTTCAGAGGCGTGAAGGCGGGTTTCGTAAGCCGGGCTTTGGAG
GCAGGTCCTCCAGCAGTTTTTCCCGCGGAAACAGGGGCCATTAA

Upstream 100 bases:

>100_bases
TTTCTTCCGGCAAAAGAAAGCCTCCTCTTTTTGAGGATGTGAATTGCCGTAATATAAACAATACAAAATCATCCGCTGAG
ATAGCGGACATTATACCAAT

Downstream 100 bases:

>100_bases
TGAATGACTTGTTCCGGTATGAAGAAACATTGCAGATGGTGGCTTTTTGCCGGATTGTGGGGACTGTCCCTCGTTCAGCA
TCCACTTCTTGCTTCTCAGA

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSEEQHGSEENGGIRINKFLASCGIDSRRVADRLIGEGRVEVNGKVIDTPGMRVTEKDFVKVDGRHMTPMEEVVVLLNKP
RGYVCSREAQGAIGTVYDLLPPRLRHLNYVGRLDADSEGLLIMTNKGELTQVLSHPTGGIEKEYWVTVDQNFDNSVLMQF
LRGVRIPEGNAKAKYVCRASARRACIVLEQGLKRQVRQMFQCLGLRVRKLVRVRIGSLWGGDLEPGGWKFLDDADVALSL
KNPPRQRKYLGASQLVAGGGAKGEQGGRGVDSDEDYVFNPEDFEAGDSYEPTPEMKTRFVETEDEREVKEDGYFRGDSGF
RSRDRRGDFHRRGDGFRGRRGDGALRREAGFKEERRKGGFQRREGGFGRDRREGGFQHQEGGFRENRREGGFQRREGGFG
RDRREGGFQHQERGFRENRREGGFQRREGGFGRDRRGGGFQRREGGFRKPGFGGRSSSSFSRGNRGH

Sequences:

>Translated_467_residues
MSEEQHGSEENGGIRINKFLASCGIDSRRVADRLIGEGRVEVNGKVIDTPGMRVTEKDFVKVDGRHMTPMEEVVVLLNKP
RGYVCSREAQGAIGTVYDLLPPRLRHLNYVGRLDADSEGLLIMTNKGELTQVLSHPTGGIEKEYWVTVDQNFDNSVLMQF
LRGVRIPEGNAKAKYVCRASARRACIVLEQGLKRQVRQMFQCLGLRVRKLVRVRIGSLWGGDLEPGGWKFLDDADVALSL
KNPPRQRKYLGASQLVAGGGAKGEQGGRGVDSDEDYVFNPEDFEAGDSYEPTPEMKTRFVETEDEREVKEDGYFRGDSGF
RSRDRRGDFHRRGDGFRGRRGDGALRREAGFKEERRKGGFQRREGGFGRDRREGGFQHQEGGFRENRREGGFQRREGGFG
RDRREGGFQHQERGFRENRREGGFQRREGGFGRDRRGGGFQRREGGFRKPGFGGRSSSSFSRGNRGH
>Mature_466_residues
SEEQHGSEENGGIRINKFLASCGIDSRRVADRLIGEGRVEVNGKVIDTPGMRVTEKDFVKVDGRHMTPMEEVVVLLNKPR
GYVCSREAQGAIGTVYDLLPPRLRHLNYVGRLDADSEGLLIMTNKGELTQVLSHPTGGIEKEYWVTVDQNFDNSVLMQFL
RGVRIPEGNAKAKYVCRASARRACIVLEQGLKRQVRQMFQCLGLRVRKLVRVRIGSLWGGDLEPGGWKFLDDADVALSLK
NPPRQRKYLGASQLVAGGGAKGEQGGRGVDSDEDYVFNPEDFEAGDSYEPTPEMKTRFVETEDEREVKEDGYFRGDSGFR
SRDRRGDFHRRGDGFRGRRGDGALRREAGFKEERRKGGFQRREGGFGRDRREGGFQHQEGGFRENRREGGFQRREGGFGR
DRREGGFQHQERGFRENRREGGFQRREGGFGRDRRGGGFQRREGGFRKPGFGGRSSSSFSRGNRGH

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=240, Percent_Identity=35.4166666666667, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787524, Length=239, Percent_Identity=33.4728033472803, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788510, Length=231, Percent_Identity=29.8701298701299, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 52736; Mature: 52605

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEQHGSEENGGIRINKFLASCGIDSRRVADRLIGEGRVEVNGKVIDTPGMRVTEKDFV
CCCCCCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHCCCEEEECCEEECCCCCEECCCHHE
KVDGRHMTPMEEVVVLLNKPRGYVCSREAQGAIGTVYDLLPPRLRHLNYVGRLDADSEGL
EECCCCCCCHHHHHHHHCCCCCCEECCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCE
LIMTNKGELTQVLSHPTGGIEKEYWVTVDQNFDNSVLMQFLRGVRIPEGNAKAKYVCRAS
EEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHC
ARRACIVLEQGLKRQVRQMFQCLGLRVRKLVRVRIGSLWGGDLEPGGWKFLDDADVALSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEE
KNPPRQRKYLGASQLVAGGGAKGEQGGRGVDSDEDYVFNPEDFEAGDSYEPTPEMKTRFV
CCCCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHCC
ETEDEREVKEDGYFRGDSGFRSRDRRGDFHRRGDGFRGRRGDGALRREAGFKEERRKGGF
CCCHHHHHHHCCCEECCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHHHCCC
QRREGGFGRDRREGGFQHQEGGFRENRREGGFQRREGGFGRDRREGGFQHQERGFRENRR
CHHCCCCCCCHHHCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHHCCCCHHHHHHHHHHH
EGGFQRREGGFGRDRRGGGFQRREGGFRKPGFGGRSSSSFSRGNRGH
HCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEEQHGSEENGGIRINKFLASCGIDSRRVADRLIGEGRVEVNGKVIDTPGMRVTEKDFV
CCCCCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHCCCEEEECCEEECCCCCEECCCHHE
KVDGRHMTPMEEVVVLLNKPRGYVCSREAQGAIGTVYDLLPPRLRHLNYVGRLDADSEGL
EECCCCCCCHHHHHHHHCCCCCCEECCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCE
LIMTNKGELTQVLSHPTGGIEKEYWVTVDQNFDNSVLMQFLRGVRIPEGNAKAKYVCRAS
EEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHC
ARRACIVLEQGLKRQVRQMFQCLGLRVRKLVRVRIGSLWGGDLEPGGWKFLDDADVALSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEE
KNPPRQRKYLGASQLVAGGGAKGEQGGRGVDSDEDYVFNPEDFEAGDSYEPTPEMKTRFV
CCCCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHCC
ETEDEREVKEDGYFRGDSGFRSRDRRGDFHRRGDGFRGRRGDGALRREAGFKEERRKGGF
CCCHHHHHHHCCCEECCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCHHHHHHCCC
QRREGGFGRDRREGGFQHQEGGFRENRREGGFQRREGGFGRDRREGGFQHQERGFRENRR
CHHCCCCCCCHHHCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHHCCCCHHHHHHHHHHH
EGGFQRREGGFGRDRRGGGFQRREGGFRKPGFGGRSSSSFSRGNRGH
HCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]