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The map label for this gene is ywaD [H]

Identifier: 187734647

GI number: 187734647

Start: 164276

End: 165220

Strand: Direct

Name: ywaD [H]

Synonym: Amuc_0134

Alternate gene names: 187734647

Gene position: 164276-165220 (Clockwise)

Preceding gene: 187734646

Following gene: 187734648

Centisome position: 6.17

GC content: 59.37

Gene sequence:

>945_bases
ATGACGCCCCGCATCGGACTTCTCCTGTTCACGGCCCTGCTGATGCAGTGCGAAAACCCCGTGGAAACGCCCGTGCCCGG
TAAGGAAACCGTTCCCGCGCAAATCCGGCAAACGAATTGTTTCAACGGAGGAAACGCTCTGTTCCACGCCGCGCGGATAA
CGGAAATGGGGAATCGTGCTTCAGGCACTCCCGGCTACCGCAGGCAGATGGACTACCTGAAGGAGGAACTGGCCAAATGC
GGCTGGACCTGCCGGGAACAGGCTTTTGAAAAGGAAACGCCCCAGGGCCCCGTCCGGTTCGTCAACCTGAGGGCCCGTTT
TGGCAAGGCTCCAAACTTCCTGGATCCGGTTCGGGGCCTGCTGACCTGCCACATTGACACCAAGCGGGGCATCGACGGAT
TCACCGGCGCCAATGACGGGGCATCGGGAGCTGCGGCCATTCTGGAGACAGCCCGCATTCTGTCCGGAGACCCCGCACGC
GCCGGAAATTTGGAGCTTGTGTTTTTTGACGGGGAAGAAAGTTTTGCGGAACATATGGACAGCGACGACGGCCTGTACGG
CTCCAGGCATTACGCATCCTCCATGCGGCAGCCGCTTCCCGAATGGATGATCAATTTGGACATGGTGGGGCGGCAGGGTA
AAAAGATACGCATCCCGGCCATGACGCCCCAATCCATGTACCGGGTTTATTCCCGCGCCATCCGTGAACTGGGTTATTCC
CCGGAGGAATGGGGAGTATCCGGCTATGCCATCCTGGATGACCACGTTCCTTTCATGGAGCGCGGCGTGGACACGTTGAA
CCTGATTGACGACTTCCAGGACGGCAACTGGTGGCACACCTCCAAGGATAACATCGGCATTCTGGGCGAAAAATCCTTCC
AGCAAACCGGGGAAATGACCCTTCACATCCTCCGGCAACTGCTTCCCGGCCCGCCCTCCGCCTGA

Upstream 100 bases:

>100_bases
GAAATCACCTTCTCCAGCAAAGCGGAATTCATCCGCATCCTTGAGCTTCTGGGCCAGGATGAATGGCCTGATTCCAAGTA
AACTTCCCCCCCCTTTTTCC

Downstream 100 bases:

>100_bases
CCAGGCAGCTCTGACCCTCCAATTATCCCTGTCCCGCCATGTCCTTCAACTCTCCCTGGCTGCTGTGGGCTCTCTTTGCA
GCCTCCGTTCCCATCATCAT

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTPRIGLLLFTALLMQCENPVETPVPGKETVPAQIRQTNCFNGGNALFHAARITEMGNRASGTPGYRRQMDYLKEELAKC
GWTCREQAFEKETPQGPVRFVNLRARFGKAPNFLDPVRGLLTCHIDTKRGIDGFTGANDGASGAAAILETARILSGDPAR
AGNLELVFFDGEESFAEHMDSDDGLYGSRHYASSMRQPLPEWMINLDMVGRQGKKIRIPAMTPQSMYRVYSRAIRELGYS
PEEWGVSGYAILDDHVPFMERGVDTLNLIDDFQDGNWWHTSKDNIGILGEKSFQQTGEMTLHILRQLLPGPPSA

Sequences:

>Translated_314_residues
MTPRIGLLLFTALLMQCENPVETPVPGKETVPAQIRQTNCFNGGNALFHAARITEMGNRASGTPGYRRQMDYLKEELAKC
GWTCREQAFEKETPQGPVRFVNLRARFGKAPNFLDPVRGLLTCHIDTKRGIDGFTGANDGASGAAAILETARILSGDPAR
AGNLELVFFDGEESFAEHMDSDDGLYGSRHYASSMRQPLPEWMINLDMVGRQGKKIRIPAMTPQSMYRVYSRAIRELGYS
PEEWGVSGYAILDDHVPFMERGVDTLNLIDDFQDGNWWHTSKDNIGILGEKSFQQTGEMTLHILRQLLPGPPSA
>Mature_313_residues
TPRIGLLLFTALLMQCENPVETPVPGKETVPAQIRQTNCFNGGNALFHAARITEMGNRASGTPGYRRQMDYLKEELAKCG
WTCREQAFEKETPQGPVRFVNLRARFGKAPNFLDPVRGLLTCHIDTKRGIDGFTGANDGASGAAAILETARILSGDPARA
GNLELVFFDGEESFAEHMDSDDGLYGSRHYASSMRQPLPEWMINLDMVGRQGKKIRIPAMTPQSMYRVYSRAIRELGYSP
EEWGVSGYAILDDHVPFMERGVDTLNLIDDFQDGNWWHTSKDNIGILGEKSFQQTGEMTLHILRQLLPGPPSA

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912618, Length=287, Percent_Identity=29.616724738676, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI92110027, Length=265, Percent_Identity=31.6981132075472, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533242, Length=270, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115533244, Length=270, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24658808, Length=284, Percent_Identity=28.8732394366197, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 34940; Mature: 34809

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRIGLLLFTALLMQCENPVETPVPGKETVPAQIRQTNCFNGGNALFHAARITEMGNRA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCC
SGTPGYRRQMDYLKEELAKCGWTCREQAFEKETPQGPVRFVNLRARFGKAPNFLDPVRGL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCHHHHHHHH
LTCHIDTKRGIDGFTGANDGASGAAAILETARILSGDPARAGNLELVFFDGEESFAEHMD
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCC
SDDGLYGSRHYASSMRQPLPEWMINLDMVGRQGKKIRIPAMTPQSMYRVYSRAIRELGYS
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCC
PEEWGVSGYAILDDHVPFMERGVDTLNLIDDFQDGNWWHTSKDNIGILGEKSFQQTGEMT
CHHHCCCCEEEECCCCCHHHHCCCHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHHHH
LHILRQLLPGPPSA
HHHHHHHCCCCCCC
>Mature Secondary Structure 
TPRIGLLLFTALLMQCENPVETPVPGKETVPAQIRQTNCFNGGNALFHAARITEMGNRA
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCC
SGTPGYRRQMDYLKEELAKCGWTCREQAFEKETPQGPVRFVNLRARFGKAPNFLDPVRGL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCHHHHHHHH
LTCHIDTKRGIDGFTGANDGASGAAAILETARILSGDPARAGNLELVFFDGEESFAEHMD
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHCC
SDDGLYGSRHYASSMRQPLPEWMINLDMVGRQGKKIRIPAMTPQSMYRVYSRAIRELGYS
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCC
PEEWGVSGYAILDDHVPFMERGVDTLNLIDDFQDGNWWHTSKDNIGILGEKSFQQTGEMT
CHHHCCCCEEEECCCCCHHHHCCCHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHHHH
LHILRQLLPGPPSA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]