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The map label for this gene is folE2

Identifier: 187734607

GI number: 187734607

Start: 120747

End: 121541

Strand: Reverse

Name: folE2

Synonym: Amuc_0093

Alternate gene names: 187734607

Gene position: 121541-120747 (Counterclockwise)

Preceding gene: 187734608

Following gene: 187734606

Centisome position: 4.56

GC content: 55.47

Gene sequence:

>795_bases
ATGCAGGAACTGAAAGATACCCAGTCCGAGGCGGATACGCGCAATATTTCCATTGACCGGGTGGGCGTAAAAGGGTTGCG
CTTCCCCATCCAGATACAGGACAAGCTCAACCGCATCCAGTCCACTGTGGCGACGGTTTCTCTGGCGGTGGATCTGCCGG
AAGAATTCAAGGGCACCCATATGAGCCGTTTTGTGGAGGCGTTGCACCAGCATGGCCCTTTGCTGGATGTGCATACGGCC
CTGGCCATTCCGCGGGAACTGCTCCGCCGTCTGTCCGCCCGCCGTTCCCATGTGGAAATGGAATTCCCGTTTTTCCGCTC
CAAAAACGCTCCTGTGACCGGAATTGAAGGGCTCATGGATTACGTTGTCCGGTTTGAGATGGAGGCGGAAGCGAACAACA
AACTGGCTGATTTCAAGCTGACAGTTATCGTTCCCGTGACGACGCTCTGCCCCTGCTCCAAGGCCATGAGTGCCTACGGA
GCCCACAACCAGCGCGGGCTGGTTACTTATTCCGTGCGTTTTGCCTCCAGGCCCGTCTGGATTGAAGACCTGATTGACCT
GGTGGAATCCTGCGCGAGCTGCTCCCTGTTCAGCGTGCTGAAAAGGCCGGATGAAAAATGGGTGACGGAAAAGGCTTATG
AAAACCCTGTCTTTGTGGAAGATCTGGTGCGCAACGTGGCGTTGAAAACGCAGAGTCATTCCGCCTTCAGCTGGTACCGG
GTGGAAGCGGAAAATTTTGAATCCATCCATAACCACCAGGCATACGCCGTCATTGAGCGCGATTTGCGTTCCTGA

Upstream 100 bases:

>100_bases
CAAGGAAAATCTCTTTCGGTAGAATTGTCTTTGCAGGCGGGAGTTTGTCCGGTAACAGGGCAGACTCCCGCTTTATTTCC
ACCCATCATCCTTTTTCCCC

Downstream 100 bases:

>100_bases
ACCATTTCCGGGCCGGATTTATGAACGATAACTGGTGGGCCATTGCCTCTCTCATCCTCTCCCTGGCTTTCACAGGGCTG
GGATGGCGCCTGCTGGCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQELKDTQSEADTRNISIDRVGVKGLRFPIQIQDKLNRIQSTVATVSLAVDLPEEFKGTHMSRFVEALHQHGPLLDVHTA
LAIPRELLRRLSARRSHVEMEFPFFRSKNAPVTGIEGLMDYVVRFEMEAEANNKLADFKLTVIVPVTTLCPCSKAMSAYG
AHNQRGLVTYSVRFASRPVWIEDLIDLVESCASCSLFSVLKRPDEKWVTEKAYENPVFVEDLVRNVALKTQSHSAFSWYR
VEAENFESIHNHQAYAVIERDLRS

Sequences:

>Translated_264_residues
MQELKDTQSEADTRNISIDRVGVKGLRFPIQIQDKLNRIQSTVATVSLAVDLPEEFKGTHMSRFVEALHQHGPLLDVHTA
LAIPRELLRRLSARRSHVEMEFPFFRSKNAPVTGIEGLMDYVVRFEMEAEANNKLADFKLTVIVPVTTLCPCSKAMSAYG
AHNQRGLVTYSVRFASRPVWIEDLIDLVESCASCSLFSVLKRPDEKWVTEKAYENPVFVEDLVRNVALKTQSHSAFSWYR
VEAENFESIHNHQAYAVIERDLRS
>Mature_264_residues
MQELKDTQSEADTRNISIDRVGVKGLRFPIQIQDKLNRIQSTVATVSLAVDLPEEFKGTHMSRFVEALHQHGPLLDVHTA
LAIPRELLRRLSARRSHVEMEFPFFRSKNAPVTGIEGLMDYVVRFEMEAEANNKLADFKLTVIVPVTTLCPCSKAMSAYG
AHNQRGLVTYSVRFASRPVWIEDLIDLVESCASCSLFSVLKRPDEKWVTEKAYENPVFVEDLVRNVALKTQSHSAFSWYR
VEAENFESIHNHQAYAVIERDLRS

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_AKKM8 (B2ULP4)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001876719.1
- ProteinModelPortal:   B2ULP4
- SMR:   B2ULP4
- GeneID:   6274987
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0093
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- ProtClustDB:   CLSK2337785
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 30079; Mature: 30079

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELKDTQSEADTRNISIDRVGVKGLRFPIQIQDKLNRIQSTVATVSLAVDLPEEFKGTH
CCCHHHHHHHCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEECCCHHHCCCH
MSRFVEALHQHGPLLDVHTALAIPRELLRRLSARRSHVEMEFPFFRSKNAPVTGIEGLMD
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHH
YVVRFEMEAEANNKLADFKLTVIVPVTTLCPCSKAMSAYGAHNQRGLVTYSVRFASRPVW
HHHHHHCCCCCCCCEEEEEEEEEEECHHHCCHHHHHHHHCCCCCCCEEEEEEEECCCCCC
IEDLIDLVESCASCSLFSVLKRPDEKWVTEKAYENPVFVEDLVRNVALKTQSHSAFSWYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEE
VEAENFESIHNHQAYAVIERDLRS
ECHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MQELKDTQSEADTRNISIDRVGVKGLRFPIQIQDKLNRIQSTVATVSLAVDLPEEFKGTH
CCCHHHHHHHCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEECCCHHHCCCH
MSRFVEALHQHGPLLDVHTALAIPRELLRRLSARRSHVEMEFPFFRSKNAPVTGIEGLMD
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHH
YVVRFEMEAEANNKLADFKLTVIVPVTTLCPCSKAMSAYGAHNQRGLVTYSVRFASRPVW
HHHHHHCCCCCCCCEEEEEEEEEEECHHHCCHHHHHHHHCCCCCCCEEEEEEEECCCCCC
IEDLIDLVESCASCSLFSVLKRPDEKWVTEKAYENPVFVEDLVRNVALKTQSHSAFSWYR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEE
VEAENFESIHNHQAYAVIERDLRS
ECHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA