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The map label for this gene is glsA

Identifier: 187734554

GI number: 187734554

Start: 53441

End: 54382

Strand: Direct

Name: glsA

Synonym: Amuc_0038

Alternate gene names: 187734554

Gene position: 53441-54382 (Clockwise)

Preceding gene: 187734553

Following gene: 187734556

Centisome position: 2.01

GC content: 57.43

Gene sequence:

>942_bases
ATGAGTGACATTCCTTCCAATGAACAGATCCGGACGGCCCTGGATAACGCATACGCCTACGCCAAAACCGTCCAGGGAGG
CAAAAACGCCTCGTACATTCCCGCCCTGGCCCAGGTGCCTTCCGACCTGCTGGCGATTGCCGTGGTCACCGTCAACGGAG
ACCTGCTGACCGCAGGCTCCGCGGACGCGCCCTTCGCCATTGAATCCATTTCCAAGGCATTCAACCTGGCTTATGTCATG
GATCTGATCGGCATGAAGCAGCTGCGCGCGAAAATCGGAGCGGACCCCACCGGGGAACCCTTCAATTCCGTAATGGCCAT
TGAGCTGCACGGCGGCAAGCCCCTCAATCCCCTGGTCAACGCAGGGGCCATGGCGACGGTCAGCCTGGTCAACGGTTCGG
ATTCCGATGAAATATGGGGAAACATGATCCATAATTTCAATAACTTCGCCAACACGGCCCTGACTGTGAACCAGGAGATT
TACAAGTCGGAAAGCGCTACCAACCAGCACAACCGCGGCATTGCCTGGCTGCTGGACAGCTACGGCTATTTTTACAATAC
GCCGCCCATGATTGTGGATTTGTACACACGCATGTGTTCCCTGAATATCACCGCTTCCCAGCTGGCCCTGATGGGCGCCT
GCTACGCCAACGGCGGAGTCAATCCCGTCAGCAAGAAGCGTGTGGTGAAAGAGGAGAACGTTCCCCCCATTTTGGCGGAA
ATGTGCATGTCAGGCCTTTATGATTCCACAGGGGACTGGATGTACAAAGCCGGCCTTCCGGCCAAGTCCGGCGTGGGAGG
CGGCCTGGTAGCCGTAGCTCCCGGCAAGCTGGCCATGGCGGCTTTTTCGCCTCCCCTGGATCCCGCAGGGAATACCGTCA
AGGGGCAGGCGGCACTTCAATCCATCATCAGGGAACTGAATCTAAACCTTTTCCGGAGTTGA

Upstream 100 bases:

>100_bases
TGGAAACGGCCGGTGGATCCCGAAGACGCCTTTGAACCCTTCGGATGGGAGAAAAACAATGATTCCCATTCCGCAGCAAC
CCCTAGCCATTCCATATCCC

Downstream 100 bases:

>100_bases
TCCGGGATGAGAAGGTAAACCCGCGGAGCCAAAATCCGAAAGGATTCCCGCGGGTTTACTGTATCCTGTCCAGCCCCCCG
AGGCAGACCGCAGTTTCTCG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSDIPSNEQIRTALDNAYAYAKTVQGGKNASYIPALAQVPSDLLAIAVVTVNGDLLTAGSADAPFAIESISKAFNLAYVM
DLIGMKQLRAKIGADPTGEPFNSVMAIELHGGKPLNPLVNAGAMATVSLVNGSDSDEIWGNMIHNFNNFANTALTVNQEI
YKSESATNQHNRGIAWLLDSYGYFYNTPPMIVDLYTRMCSLNITASQLALMGACYANGGVNPVSKKRVVKEENVPPILAE
MCMSGLYDSTGDWMYKAGLPAKSGVGGGLVAVAPGKLAMAAFSPPLDPAGNTVKGQAALQSIIRELNLNLFRS

Sequences:

>Translated_313_residues
MSDIPSNEQIRTALDNAYAYAKTVQGGKNASYIPALAQVPSDLLAIAVVTVNGDLLTAGSADAPFAIESISKAFNLAYVM
DLIGMKQLRAKIGADPTGEPFNSVMAIELHGGKPLNPLVNAGAMATVSLVNGSDSDEIWGNMIHNFNNFANTALTVNQEI
YKSESATNQHNRGIAWLLDSYGYFYNTPPMIVDLYTRMCSLNITASQLALMGACYANGGVNPVSKKRVVKEENVPPILAE
MCMSGLYDSTGDWMYKAGLPAKSGVGGGLVAVAPGKLAMAAFSPPLDPAGNTVKGQAALQSIIRELNLNLFRS
>Mature_312_residues
SDIPSNEQIRTALDNAYAYAKTVQGGKNASYIPALAQVPSDLLAIAVVTVNGDLLTAGSADAPFAIESISKAFNLAYVMD
LIGMKQLRAKIGADPTGEPFNSVMAIELHGGKPLNPLVNAGAMATVSLVNGSDSDEIWGNMIHNFNNFANTALTVNQEIY
KSESATNQHNRGIAWLLDSYGYFYNTPPMIVDLYTRMCSLNITASQLALMGACYANGGVNPVSKKRVVKEENVPPILAEM
CMSGLYDSTGDWMYKAGLPAKSGVGGGLVAVAPGKLAMAAFSPPLDPAGNTVKGQAALQSIIRELNLNLFRS

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=310, Percent_Identity=33.5483870967742, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI20336214, Length=310, Percent_Identity=31.2903225806452, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786693, Length=304, Percent_Identity=50.6578947368421, Blast_Score=322, Evalue=1e-89,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=35, Blast_Score=187, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17507019, Length=314, Percent_Identity=33.1210191082803, Blast_Score=182, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=307, Percent_Identity=31.2703583061889, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193204073, Length=319, Percent_Identity=29.7805642633229, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193204075, Length=321, Percent_Identity=29.595015576324, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281363241, Length=316, Percent_Identity=30.0632911392405, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24653162, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653164, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI116008307, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281363239, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653158, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653166, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653156, Length=316, Percent_Identity=30.0632911392405, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_AKKM8 (B2UL96)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001876666.1
- ProteinModelPortal:   B2UL96
- GeneID:   6275164
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0038
- HOGENOM:   HBG512335
- OMA:   LLENDHP
- ProtClustDB:   PRK12356
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33127; Mature: 32996

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIPSNEQIRTALDNAYAYAKTVQGGKNASYIPALAQVPSDLLAIAVVTVNGDLLTAGS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHEEEEEEEEECCCEEECCC
ADAPFAIESISKAFNLAYVMDLIGMKQLRAKIGADPTGEPFNSVMAIELHGGKPLNPLVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHC
AGAMATVSLVNGSDSDEIWGNMIHNFNNFANTALTVNQEIYKSESATNQHNRGIAWLLDS
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHCCCCCCCCCCCEEEEECC
YGYFYNTPPMIVDLYTRMCSLNITASQLALMGACYANGGVNPVSKKRVVKEENVPPILAE
CCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
MCMSGLYDSTGDWMYKAGLPAKSGVGGGLVAVAPGKLAMAAFSPPLDPAGNTVKGQAALQ
HHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEHHHHHH
SIIRELNLNLFRS
HHHHHHCHHHCCC
>Mature Secondary Structure 
SDIPSNEQIRTALDNAYAYAKTVQGGKNASYIPALAQVPSDLLAIAVVTVNGDLLTAGS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHEEEEEEEEECCCEEECCC
ADAPFAIESISKAFNLAYVMDLIGMKQLRAKIGADPTGEPFNSVMAIELHGGKPLNPLVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHC
AGAMATVSLVNGSDSDEIWGNMIHNFNNFANTALTVNQEIYKSESATNQHNRGIAWLLDS
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECHHHHHCCCCCCCCCCCEEEEECC
YGYFYNTPPMIVDLYTRMCSLNITASQLALMGACYANGGVNPVSKKRVVKEENVPPILAE
CCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
MCMSGLYDSTGDWMYKAGLPAKSGVGGGLVAVAPGKLAMAAFSPPLDPAGNTVKGQAALQ
HHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEHHHHHH
SIIRELNLNLFRS
HHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA