Click here to switch to the map view.

The map label for this gene is yeaJ [H]

Identifier: 187732881

GI number: 187732881

Start: 1857815

End: 1858411

Strand: Direct

Name: yeaJ [H]

Synonym: SbBS512_E2038

Alternate gene names: 187732881

Gene position: 1857815-1858411 (Clockwise)

Preceding gene: 187731228

Following gene: 187733365

Centisome position: 40.25

GC content: 43.55

Gene sequence:

>597_bases
ATGCCATTCTATTTCAGGAAGGAGTGTCCGTTAAACTCAGGCTACCTCAGCATTCGTGTCTCGTTATCCATTGATATTCT
TTACTTTATCACGTCTTCGTGGAAAAGCGTTCTGTTCTGGATTTTGACGGCGTTAATTTTGCTGAATATGGTCCGGATGC
ACTTCCGTTTATACCAAAATGTGTCGCGAGAAAATATTAGTGATGCGATGACTGGACTGTATAATCACAAAATTTTAACC
CCTGAACTGGAGCAGCGGTTGCAGAAACTGGTGCAATCCGGTTCTTCGGTGATGTTTATTGCAATTGACATGGACAAGTT
AAAGCAAATAAATGACACCCTCGGTCATCAGGAGGGGGATTTAGCGATTACGTTATTAGCTCAGGCGATTAAACAATCGA
TTCGTAAAAGTGATTATGCCATCCGACTCGGTGGCGATGAATTCTGCATCATTCTTGTCGATTCGACGCCGCAAATTGCA
GCACAACTGCCTGAACGTATCGAAAAACGTCTGCAACATATCGCGCCGCAGAAAGAAATCGGCTTCTCTTCCGGTATTTA
CGCGATGAAAGAAAACGATACGTTTGAGGTAGCCTGA

Upstream 100 bases:

>100_bases
CACTGATCGAAAGTTGATTTTCAGGAACCGTTCTGACAGCTTCGGCTTTGAACTCTTTAGAGTAACGTTGGTTTTTTCTG
CTCATTATTAGCTCCTTCTG

Downstream 100 bases:

>100_bases
GTTTAACGGACACTCCTTCCTGAAATAGAATGGCATCAGAAGGAGCTAATAATGAGCAGAAAAAACCAACGTTACTCTAA
AGAGTTCAAAGCCGAAGCTG

Product: ggdef domain-containing protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MPFYFRKECPLNSGYLSIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNHKILT
PELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIA
AQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTFEVA

Sequences:

>Translated_198_residues
MPFYFRKECPLNSGYLSIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNHKILT
PELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIA
AQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTFEVA
>Mature_197_residues
PFYFRKECPLNSGYLSIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNHKILTP
ELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAA
QLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTFEVA

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081974, Length=181, Percent_Identity=97.7900552486188, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI145693134, Length=117, Percent_Identity=35.042735042735, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082007, Length=144, Percent_Identity=35.4166666666667, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=29.8913043478261, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788381, Length=143, Percent_Identity=29.3706293706294, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87081881, Length=112, Percent_Identity=32.1428571428571, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 22647; Mature: 22516

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFYFRKECPLNSGYLSIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQN
CCCCCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRENISDAMTGLYNHKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGD
HCHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCC
LAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEI
HHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHC
GFSSGIYAMKENDTFEVA
CCCCCEEEEECCCEEECC
>Mature Secondary Structure 
PFYFRKECPLNSGYLSIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQN
CCCCCCCCCCCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRENISDAMTGLYNHKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGD
HCHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCC
LAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEI
HHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHC
GFSSGIYAMKENDTFEVA
CCCCCEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]