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The map label for this gene is atpA1 [H]

Identifier: 186477775

GI number: 186477775

Start: 3403773

End: 3405314

Strand: Reverse

Name: atpA1 [H]

Synonym: Bphy_3029

Alternate gene names: 186477775

Gene position: 3405314-3403773 (Counterclockwise)

Preceding gene: 186477776

Following gene: 186477774

Centisome position: 97.88

GC content: 60.7

Gene sequence:

>1542_bases
ATGCAACTCAATCCCTCTGAGATCAGCGAGCTGATCAAGAGCCGGATCCAGGGCCTTGAAGCGAGCGCAGACGTTCGCAA
CCAGGGTACCGTGATCTCCGTGACCGACGGTATCGTGCGTATCCACGGCCTGTCGGAAGTGATGCAGGGCGAAATGCTCG
AATTCCCGGGCAACGTGTACGGTCTCGCGCTGAACCTCGAGCGCGACTCGGTCGGCGCCGTGATTCTGGGTGAATACGAA
AACATCTCGGAAGGCGACATCGTCAAGACGACGGGCCGCATTCTCGAAGTGCCGGTGGGTCCGGAACTAATTGGCCGCGT
GGTCGACGCGCTGGGCAACCCGATCGACGGCAAGGGTCCGATCAACGCAAAGCTGACGGATGCAATCGAAAAGATCGCCC
CGGGCGTGATCTGGCGTAAGTCGGTGTCGCAGCCGGTGCAAACGGGCCTAAAGTCGATCGACTCGATGGTGCCGATCGGC
CGTGGCCAGCGCGAGCTGATCATCGGCGACCGCCAGTGCGGCAAGACGGCCGTGGCAGTCGACGCGATCATCAACCAGAA
GGGCAAGGACCTGATCTGTATCTACGTCGCGATCGGCCAGAAGGCTTCGTCGATCATGAACGTGGTTCGCAAGCTCGAAG
AAACGGGCGCGATGGCATACACGATCGTCGTCGCAGCTTCGGCTTCCGAGTCGGCTGCGATGCAGTACCTCGCGCCGTAC
GCCGGTTGCACGATGGGCGAATACTTCCGCGATCGCGGCCAGGACGCGCTGATCGTTTATGACGACTTGACCAAGCAGGC
TTGGGCATACCGTCAGATCTCGCTGCTGCTGCGCCGTCCGCCGGGCCGTGAAGCATATCCGGGCGACGTGTTTTATCTGC
ACTCGCGTCTGCTGGAACGTGCTGCTCGCGTCTCGGAAGAGTACGTCGAGAAGTTCACGAACGGCGAAGTGAAGGGCAAG
AGCGGCTCGCTGACGGCGCTGCCCGTCATCGAAACGCAGGCAGGCGACGTGACGGCGTTCGTTCCGACGAATGTGATCTC
GATTACCGACGGCCAGATCTTCCTGGAAACCGACCTCTTCAACGCAGGTATCCGCCCGGCTATTAACGCTGGCGTGTCGG
TGTCGCGCGTTGGCGGTGCGGCTCAGACGAAGGTTGTGAAGAAGCTGTCGGGCGGTATCCGTACCGACCTCGCACAGTAC
CGTGAACTGGCAGCATTCGCGCAGTTCGCATCGGACCTCGATGAAGCGACCCGCAAGCAGCTCGAGCGCGGCCGCCGCGT
GACGGAACTGCTGAAGCAGCCGCAGTATCAGCCGCTGCAAGTGTGGGAATTGTCGGTGTCGCTGTTCGCAGCGAACAACG
GCTACCTCGATGATCTGGAAGTGTCGCAAGTTCCGGCCTTCGAAAAGGGCATGCGCGAATTCCTGAAGTCGAAGCATGCT
GACCTGGTCAAGCGCATCGAAGACAATAAAGACTTGTCGAAGGACGACGAGGGCGCGCTGCACGCCGCACTCAAGGACTT
CAAGAAGTCGGGCGCTTATTGA

Upstream 100 bases:

>100_bases
CGCGCGCGGCTCGCCAGCATGCAGACGGCTCTGACCGCCTGAAGCCCTCACGTGGTTGTGGCGGCTGGCACGCAACAGAA
TTGACTATCAGGAGCGAATA

Downstream 100 bases:

>100_bases
TCCGCGAGTGATCCGCAAGGCATAAACGGACCTTGAAGCAGCGTGGGCGCGTGAAAGCGCGGTAACGCTGCTTCGATCAA
GGAGCAAGCAATGGCTGGAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNVYGLALNLERDSVGAVILGEYE
NISEGDIVKTTGRILEVPVGPELIGRVVDALGNPIDGKGPINAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAVDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELSVSLFAANNGYLDDLEVSQVPAFEKGMREFLKSKHA
DLVKRIEDNKDLSKDDEGALHAALKDFKKSGAY

Sequences:

>Translated_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNVYGLALNLERDSVGAVILGEYE
NISEGDIVKTTGRILEVPVGPELIGRVVDALGNPIDGKGPINAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAVDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELSVSLFAANNGYLDDLEVSQVPAFEKGMREFLKSKHA
DLVKRIEDNKDLSKDDEGALHAALKDFKKSGAY
>Mature_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNVYGLALNLERDSVGAVILGEYE
NISEGDIVKTTGRILEVPVGPELIGRVVDALGNPIDGKGPINAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAVDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELSVSLFAANNGYLDDLEVSQVPAFEKGMREFLKSKHA
DLVKRIEDNKDLSKDDEGALHAALKDFKKSGAY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=57.4509803921569, Blast_Score=590, Evalue=1e-168,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=57.4509803921569, Blast_Score=590, Evalue=1e-168,
Organism=Homo sapiens, GI32189394, Length=478, Percent_Identity=24.6861924686192, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913428, Length=324, Percent_Identity=27.1604938271605, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI19913426, Length=333, Percent_Identity=26.4264264264264, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI19913424, Length=319, Percent_Identity=26.9592476489028, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.5906432748538, Blast_Score=740, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=358, Percent_Identity=26.8156424581006, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790170, Length=377, Percent_Identity=24.6684350132626, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.4705882352941, Blast_Score=575, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.4705882352941, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.156862745098, Blast_Score=520, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI25144756, Length=410, Percent_Identity=24.8780487804878, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=378, Percent_Identity=25.6613756613757, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=320, Percent_Identity=26.5625, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=249, Percent_Identity=28.5140562248996, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=39.7260273972603, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=56.5557729941292, Blast_Score=582, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6322581, Length=426, Percent_Identity=26.056338028169, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=382, Percent_Identity=26.7015706806283, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=56.2745098039216, Blast_Score=579, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24638766, Length=420, Percent_Identity=25.2380952380952, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281361666, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646341, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136796, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28574560, Length=433, Percent_Identity=23.094688221709, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=29.4354838709677, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=29.4354838709677, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=29.4354838709677, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=28, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55789; Mature: 55789

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNVY
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCHHHHHCCCHHCCCCCEE
GLALNLERDSVGAVILGEYENISEGDIVKTTGRILEVPVGPELIGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAV
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASESAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELSVSLFAANNGYLDDLEVSQVPAFEKGMREFLKSKHA
HHHCHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
DLVKRIEDNKDLSKDDEGALHAALKDFKKSGAY
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNVY
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEECCHHHHHCCCHHCCCCCEE
GLALNLERDSVGAVILGEYENISEGDIVKTTGRILEVPVGPELIGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAV
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMAYTIVVAASASESAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELSVSLFAANNGYLDDLEVSQVPAFEKGMREFLKSKHA
HHHCHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
DLVKRIEDNKDLSKDDEGALHAALKDFKKSGAY
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA