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The map label for this gene is nlpI [C]

Identifier: 186477656

GI number: 186477656

Start: 3262614

End: 3263225

Strand: Direct

Name: nlpI [C]

Synonym: Bphy_2908

Alternate gene names: 186477656

Gene position: 3262614-3263225 (Clockwise)

Preceding gene: 186477655

Following gene: 186477670

Centisome position: 93.78

GC content: 63.89

Gene sequence:

>612_bases
ATGCACGCGCAGTCCACCGTCCCCGCTGTCCCCTCACCGTCCTGCACCGTTCACATTGTTCCCGTCACGCTCGCGTTCGC
GCTCGAAGCGCACCGCGCCTCGCGCTTTCACGAAGCCGAATCGTTGTACCGCGAAGCACTCGACGTCTGCCCCAGCCATC
CGCTCGCGCTGCATGGCTATGGCGTGCTGCTGCATCAACGCGGCCAGCATGCGCAAGCGCTCGACTACATCGACCGTTCG
CTCGAACTCGAGCCTGACAATGCGGAGTGCTGGAACGACCGCGGCTTCGTGGCCGACGCGCTCGGCGACACGGCGCTGGC
GCTGCGTTGCTACCGCGTGTCGCTGGCGCTCGATCCGCGTTCGCCCGATGCGCACAACAACATCGCCGTCGCACTCGAAG
CACAAGGCAAGCTTGACGAAGCGGTGCATCACTATCGCGAGGCGTTGAAGATCGATCCGACGCTCGCAGACGTGCATCTG
AATCTTGGCTCGGCGCTCGATCGCCTGATGAAGTTCGACGATGCCGACGAGCACTATCGCGCGCTGCTGTCGCTGAATGC
GCGCACCGCCAACGTCCGTCTGAAAACGAACGGTTCGCCAGCCCGTCAATAA

Upstream 100 bases:

>100_bases
GAAGCCCCGGACCTAACCTGTGGATGTCCCGTCGTTCACAGTCAACGTCCGGCGCATCAACGTGTGCGCCGGCTCTTTCG
AGAGTCTGGAGAGCACCGTC

Downstream 100 bases:

>100_bases
GCCTCGACGACAAACCCTCGCTGCCGCAACAGCTGCAGCACGCCCTTCTGTCCGCCCAGATGCAACGCGCCGATCGCAAC
GAACACAGGCTTGTTAGGTG

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: TPR Domain-Containing Protein; Tetratricopeptide TPR_2 Repeat Protein; Tetratricopeptide Repeat-Containing Protein; Tetratricopeptide Repeat Domain Protein; Tetratricopeptide Repeat Family; Peptidase; Tetratricopeptide TPR_1 Repeat-Containing Protein; O-Linked N-Acetylglucosamine Transferase; Methyltransferase Type; Tetratricopeptide Repeat Domain-Containing Protein; Tetratricopeptide Repeat Protein; O-Linked GlcNAc Transferase; TPR Repeat Protein; O-GlcNAc Transferase; Methyltransferase; TPR Domain Protein; Flp Pilus Assembly Protein TadD; TPR Repeat; Protein Kinase; Glycosyl Transferase Family Protein; Tetratricopeptide Tpr_1 Repeat-Containing Protein; TPR Repeat-Containing ; TPR Domain Family Protein; Polypeptide N-Acetylglucosaminyltransferase; Sulfotransferase; Peptidase S1 And S6 Chymotrypsin/Hap; Serine/Threonine Kinase; TPR/Sulfotransferase Domain-Containing Protein; SPY Protein; TPR Domain/Sulfotransferase Domain Protein; TPR Repeat-Containing Methyltransferase; Exostosin Family Protein; Two Domain Fusion Protein; Peptidase S

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MHAQSTVPAVPSPSCTVHIVPVTLAFALEAHRASRFHEAESLYREALDVCPSHPLALHGYGVLLHQRGQHAQALDYIDRS
LELEPDNAECWNDRGFVADALGDTALALRCYRVSLALDPRSPDAHNNIAVALEAQGKLDEAVHHYREALKIDPTLADVHL
NLGSALDRLMKFDDADEHYRALLSLNARTANVRLKTNGSPARQ

Sequences:

>Translated_203_residues
MHAQSTVPAVPSPSCTVHIVPVTLAFALEAHRASRFHEAESLYREALDVCPSHPLALHGYGVLLHQRGQHAQALDYIDRS
LELEPDNAECWNDRGFVADALGDTALALRCYRVSLALDPRSPDAHNNIAVALEAQGKLDEAVHHYREALKIDPTLADVHL
NLGSALDRLMKFDDADEHYRALLSLNARTANVRLKTNGSPARQ
>Mature_203_residues
MHAQSTVPAVPSPSCTVHIVPVTLAFALEAHRASRFHEAESLYREALDVCPSHPLALHGYGVLLHQRGQHAQALDYIDRS
LELEPDNAECWNDRGFVADALGDTALALRCYRVSLALDPRSPDAHNNIAVALEAQGKLDEAVHHYREALKIDPTLADVHL
NLGSALDRLMKFDDADEHYRALLSLNARTANVRLKTNGSPARQ

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307148, Length=144, Percent_Identity=34.0277777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32307150, Length=144, Percent_Identity=34.0277777777778, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI301336134, Length=170, Percent_Identity=27.6470588235294, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI83415184, Length=170, Percent_Identity=27.6470588235294, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=144, Percent_Identity=31.9444444444444, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=144, Percent_Identity=31.9444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17647755, Length=150, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585827, Length=150, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585829, Length=150, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24647123, Length=158, Percent_Identity=27.2151898734177, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22348; Mature: 22348

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAQSTVPAVPSPSCTVHIVPVTLAFALEAHRASRFHEAESLYREALDVCPSHPLALHGY
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECE
GVLLHQRGQHAQALDYIDRSLELEPDNAECWNDRGFVADALGDTALALRCYRVSLALDPR
EEEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCEEEHHCCCHHHHEEEEEEEEEECCC
SPDAHNNIAVALEAQGKLDEAVHHYREALKIDPTLADVHLNLGSALDRLMKFDDADEHYR
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCHHHHH
ALLSLNARTANVRLKTNGSPARQ
HHHHCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MHAQSTVPAVPSPSCTVHIVPVTLAFALEAHRASRFHEAESLYREALDVCPSHPLALHGY
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECE
GVLLHQRGQHAQALDYIDRSLELEPDNAECWNDRGFVADALGDTALALRCYRVSLALDPR
EEEEECCCCCHHHHHHHHHHEEECCCCCCCCCCCCEEEHHCCCHHHHEEEEEEEEEECCC
SPDAHNNIAVALEAQGKLDEAVHHYREALKIDPTLADVHLNLGSALDRLMKFDDADEHYR
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCHHHHH
ALLSLNARTANVRLKTNGSPARQ
HHHHCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA