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The map label for this gene is ygfA [C]

Identifier: 186477649

GI number: 186477649

Start: 3256437

End: 3257048

Strand: Direct

Name: ygfA [C]

Synonym: Bphy_2901

Alternate gene names: 186477649

Gene position: 3256437-3257048 (Clockwise)

Preceding gene: 186477644

Following gene: 186477651

Centisome position: 93.6

GC content: 61.44

Gene sequence:

>612_bases
TTGAACTCAAGCATAGCATGCAACCCCGCGGCGAAATCGAAAAAGGACCTGCGCGCAACACTGCTGGAAGCGCGGCTGCA
TGCGGCTCGCGAGGCAGCGAACAACGACGCGCTGGGCCGTCGAGTGCTTGATGCGTTAACGGTCTACGCGCCGACAAGTG
TAGGGTTGTACTGGCCTTTATCGGGCGAGTTCGATATGCGCGACGCGCTTGCCGTGTGGCTTTCGGGCGATGGCGCGAGG
CGCGCCGCCTTGCCCGTCATCACGGGGCGCGACAAGCCGCTCGAATTTCATGTGTGGACACCGGATATGCCGATGCAAGT
TGGGGCTCATCGGATTCATGAGCCGACTTCCGGTGAGGTCATCGTGCCTGATGTGCTGTTTGTGCCGTGCGTCGGGTTTG
ATGCCGATCGATATCGGCTTGGATACGGTGGCGGCTACTACGACCGCACGCTCGCTGCGTTTCGTCGTGCCGGAGGCCCC
GTCCCCGTGACCGTGGGCATCGCGTATGAAGCGTGTCGTACAGATGCTCTCGCACGCGAGGCGCATGATATTCCGCTTGA
TGCTGTGATCACCGATGCCCGGTGGTATTCCGAGCCGGCAGCTTCGGTGTAA

Upstream 100 bases:

>100_bases
CGCGACGAGTGCCGCCGCGGCGAGCGCCAGACTGGCCGCGCGATATACTCGGAAAAGGCGTTTGGACATCGTTATTTCTA
GAGCGTTTCTGGAGCGCGAA

Downstream 100 bases:

>100_bases
CTGTGCTGTGGAGTTTCTTCGCTGGCACCCGCATCGTTTCTCCCGTTAGCTGGCGTTGCCTTGCGCGGGGCAACGCGTGA
AGCACGAGCGCAAAACGCGG

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MNSSIACNPAAKSKKDLRATLLEARLHAAREAANNDALGRRVLDALTVYAPTSVGLYWPLSGEFDMRDALAVWLSGDGAR
RAALPVITGRDKPLEFHVWTPDMPMQVGAHRIHEPTSGEVIVPDVLFVPCVGFDADRYRLGYGGGYYDRTLAAFRRAGGP
VPVTVGIAYEACRTDALAREAHDIPLDAVITDARWYSEPAASV

Sequences:

>Translated_203_residues
MNSSIACNPAAKSKKDLRATLLEARLHAAREAANNDALGRRVLDALTVYAPTSVGLYWPLSGEFDMRDALAVWLSGDGAR
RAALPVITGRDKPLEFHVWTPDMPMQVGAHRIHEPTSGEVIVPDVLFVPCVGFDADRYRLGYGGGYYDRTLAAFRRAGGP
VPVTVGIAYEACRTDALAREAHDIPLDAVITDARWYSEPAASV
>Mature_203_residues
MNSSIACNPAAKSKKDLRATLLEARLHAAREAANNDALGRRVLDALTVYAPTSVGLYWPLSGEFDMRDALAVWLSGDGAR
RAALPVITGRDKPLEFHVWTPDMPMQVGAHRIHEPTSGEVIVPDVLFVPCVGFDADRYRLGYGGGYYDRTLAAFRRAGGP
VPVTVGIAYEACRTDALAREAHDIPLDAVITDARWYSEPAASV

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=175, Percent_Identity=29.7142857142857, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22021; Mature: 22021

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSIACNPAAKSKKDLRATLLEARLHAAREAANNDALGRRVLDALTVYAPTSVGLYWPL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECC
SGEFDMRDALAVWLSGDGARRAALPVITGRDKPLEFHVWTPDMPMQVGAHRIHEPTSGEV
CCCCCCCCEEEEEECCCCCCCEECEEEECCCCCEEEEEECCCCCHHHHHHHCCCCCCCCE
IVPDVLFVPCVGFDADRYRLGYGGGYYDRTLAAFRRAGGPVPVTVGIAYEACRTDALARE
EECCHHEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
AHDIPLDAVITDARWYSEPAASV
HCCCCHHHEEECCHHCCCCCCCC
>Mature Secondary Structure
MNSSIACNPAAKSKKDLRATLLEARLHAAREAANNDALGRRVLDALTVYAPTSVGLYWPL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECC
SGEFDMRDALAVWLSGDGARRAALPVITGRDKPLEFHVWTPDMPMQVGAHRIHEPTSGEV
CCCCCCCCEEEEEECCCCCCCEECEEEECCCCCEEEEEECCCCCHHHHHHHCCCCCCCCE
IVPDVLFVPCVGFDADRYRLGYGGGYYDRTLAAFRRAGGPVPVTVGIAYEACRTDALARE
EECCHHEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHH
AHDIPLDAVITDARWYSEPAASV
HCCCCHHHEEECCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]