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The map label for this gene is mlaC [H]

Identifier: 186477514

GI number: 186477514

Start: 3116003

End: 3116632

Strand: Reverse

Name: mlaC [H]

Synonym: Bphy_2766

Alternate gene names: 186477514

Gene position: 3116632-3116003 (Counterclockwise)

Preceding gene: 186477515

Following gene: 186477513

Centisome position: 89.58

GC content: 60.16

Gene sequence:

>630_bases
ATGAAAAAATTCTTCTTCATCCCGTTTATGGCAGCGCTGTTTGCGTTCGGTAGCGCGGCGTCCGCGCAAACCGTGGATAC
CAGCAATCCCGACGTGATGGTCAAGACGGTCACGCAGCAGGTGATCGACGCCGTGCGTGCCGACAAGACCATCCAGACAG
GCAACATCGGCGCCGTCACGAAACTCGTGAACGAGAAGATTCTCCCGTACACGGACTTCCGCCGTACGACGCAACTCGCG
ATGGGCCGCAACTGGCGTAGCGCGACGCCCGAGCAGCAGAACGCCGTCGTCGAGCAGTTCAAGACGCTGCTGATCCGCAC
GTATTCGGGCGCGCTGGCGCAGGTCAAGGATCAGCAGATCGAATACAAGCCGTTCCGTGCAAATCCGGAAGATACCGACG
TGGTGGTGCGTTCGGTGGTGATGAACAACGGCTCGCCCGTCGAACTCGATTACCGTCTGTACAAGACCCCGCAAGGCTGG
CGCGTGTATGACCTGAACGTGCTCGGCGCATGGCTGATCCAGGCGTACCAGCAGCAGTTCAACGAGCAGATCCAGAAGAG
CGGCGTCGACGGTCTGATCCAGTTCCTGACGGCACGCAACCAGCAACTCGCGGGCGGCAAGCAGTCGTGA

Upstream 100 bases:

>100_bases
CACTCGGATACGAATCTCGCAGTTTCGGCGTGGATTGCGTCTGAACTCGCGTGATATTGTCGCCTCCAACGCTAAGCTTA
TTTTTTTTGCAGGACTGGAA

Downstream 100 bases:

>100_bases
ATAACATTGCAAGCGCGCCGGTGACGCCGCCCACCCATTCATTCGAAACGGGCGCCACGCTGACCCACGCGAGCGCGAAA
GCCGCGCTCGCGGCAGGGCT

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKKFFFIPFMAALFAFGSAASAQTVDTSNPDVMVKTVTQQVIDAVRADKTIQTGNIGAVTKLVNEKILPYTDFRRTTQLA
MGRNWRSATPEQQNAVVEQFKTLLIRTYSGALAQVKDQQIEYKPFRANPEDTDVVVRSVVMNNGSPVELDYRLYKTPQGW
RVYDLNVLGAWLIQAYQQQFNEQIQKSGVDGLIQFLTARNQQLAGGKQS

Sequences:

>Translated_209_residues
MKKFFFIPFMAALFAFGSAASAQTVDTSNPDVMVKTVTQQVIDAVRADKTIQTGNIGAVTKLVNEKILPYTDFRRTTQLA
MGRNWRSATPEQQNAVVEQFKTLLIRTYSGALAQVKDQQIEYKPFRANPEDTDVVVRSVVMNNGSPVELDYRLYKTPQGW
RVYDLNVLGAWLIQAYQQQFNEQIQKSGVDGLIQFLTARNQQLAGGKQS
>Mature_209_residues
MKKFFFIPFMAALFAFGSAASAQTVDTSNPDVMVKTVTQQVIDAVRADKTIQTGNIGAVTKLVNEKILPYTDFRRTTQLA
MGRNWRSATPEQQNAVVEQFKTLLIRTYSGALAQVKDQQIEYKPFRANPEDTDVVVRSVVMNNGSPVELDYRLYKTPQGW
RVYDLNVLGAWLIQAYQQQFNEQIQKSGVDGLIQFLTARNQQLAGGKQS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=198, Percent_Identity=26.7676767676768, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23519; Mature: 23519

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFFFIPFMAALFAFGSAASAQTVDTSNPDVMVKTVTQQVIDAVRADKTIQTGNIGAVT
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHH
KLVNEKILPYTDFRRTTQLAMGRNWRSATPEQQNAVVEQFKTLLIRTYSGALAQVKDQQI
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
EYKPFRANPEDTDVVVRSVVMNNGSPVELDYRLYKTPQGWRVYDLNVLGAWLIQAYQQQF
CCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
NEQIQKSGVDGLIQFLTARNQQLAGGKQS
HHHHHHCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKFFFIPFMAALFAFGSAASAQTVDTSNPDVMVKTVTQQVIDAVRADKTIQTGNIGAVT
CCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHH
KLVNEKILPYTDFRRTTQLAMGRNWRSATPEQQNAVVEQFKTLLIRTYSGALAQVKDQQI
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
EYKPFRANPEDTDVVVRSVVMNNGSPVELDYRLYKTPQGWRVYDLNVLGAWLIQAYQQQF
CCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
NEQIQKSGVDGLIQFLTARNQQLAGGKQS
HHHHHHCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]