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The map label for this gene is murA

Identifier: 186477509

GI number: 186477509

Start: 3111982

End: 3113244

Strand: Reverse

Name: murA

Synonym: Bphy_2761

Alternate gene names: 186477509

Gene position: 3113244-3111982 (Counterclockwise)

Preceding gene: 186477510

Following gene: 186477508

Centisome position: 89.48

GC content: 63.9

Gene sequence:

>1263_bases
ATGGACAAACTCGTGATTGAAGGCGGGCAGAAGCTCGCTGGTGAGATCGTTGTTTCGGGTGCGAAGAACGCGGCGCTGCC
GATCCTTTGCGCAGGCTTGTTGAGCGCGGAGCCCGTGCATCTCGACAACGTGCCCGATCTGCAGGACGTGCGCACCACGC
TCAAACTGCTTGGTCAGATGGGCGTGCGCACGGAAAGCGCAGACGGCAAGGTGTCGCTCGACGCGTCGAAGGTCGACAAT
CTCGTCGCGCCGTACGAACTCGTAAAGACAATGCGCGCGTCGATTCTCGTGCTCGGTCCGCTCGTCGCGCGTTTCGGCGA
GGCGAAGGTTTCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGCCCGGTGGATCAGCACATCAAGGGCCTGCAGGCGATGG
GCGCCGAGATCAATATCGAGCACGGCTTCATCGAAGCGCGCGCGAAGCGTCTGAAAGGCGCGCGCATCATCACCGACATG
ATCACCGTCACGGGCACGGAAAACCTGCTGATGGCAGCGGTGCTGGCGGACGGCGAAACGATCATCGAGAACGCCGCGCG
CGAGCCGGAAGTCGGCGATCTGGCGAGTCTGCTCGTTTCGATGGGCGCGAAGATCGAGGGCATCGGCACCGATCGTCTCG
TCATCCAGGGCGTCGACAAGCTGCACGGCGCGAAGCACACGGTCGTGCCTGATCGCATCGAAGCGGGCACCTTCCTGTGC
GCGGTCGCGGCGGCAGGCGGCGACGTGACGCTGCGTCACGTGCGCCCGCAGATTCTCGAAGCCGTGACGGACAAGCTGCG
CGACGCCGGCGTGACAATTGAAGAAGGCGACGACTGGATGCGCGTGCGCATGAACCAGCGTCCGAAGGCCGTGTCGTTCC
GCACATCGGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAATTCATGGCGCTCAACACGCTCGCGGAAGGCACGTCG
CAAGTCGTCGAAACGATCTTCGAAAACCGCTTCATGCACGTGCAGGAACTGAACCGTCTCGGCGCGAACATCACGATCGA
CGGCAAGACGGCGCTCGTCAACGGCGTCGAAAAGCTGTCGGGTGCGAAGGTGATGGCGACCGACCTGCGCGCGTCGGCGA
GCCTCGTGATCGCGGGTCTGTGCGCGGACGGCGAAACGCTGATCGACCGCATCTATCATCTCGATCGCGGCTACGACCGG
ATGGAATCGAAACTCACCGCAGTCGGCGCGAAGGTGCGCCGCATCAAGGGTAATCAGGCATGA

Upstream 100 bases:

>100_bases
CACACAAGACACACAAGAGAGCCGCGACGCCGCGCATGGCGCCGCAGCAACCGCCCACAAGACGCCCGTTGGCGGACGGG
CAGACCAGGAACAAACAGGC

Downstream 100 bases:

>100_bases
GCGAATTGCCGCAAACGTCGTCGTCGCCCGCAGCCGGCAAGCCGCTGACGCTCGCGCTGTCGAAGGGCCGCATTTTCGAG
GAAACGGTGCCGCTGCTCGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKLVIEGGQKLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPDLQDVRTTLKLLGQMGVRTESADGKVSLDASKVDN
LVAPYELVKTMRASILVLGPLVARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEINIEHGFIEARAKRLKGARIITDM
ITVTGTENLLMAAVLADGETIIENAAREPEVGDLASLLVSMGAKIEGIGTDRLVIQGVDKLHGAKHTVVPDRIEAGTFLC
AVAAAGGDVTLRHVRPQILEAVTDKLRDAGVTIEEGDDWMRVRMNQRPKAVSFRTSEYPAFPTDMQAQFMALNTLAEGTS
QVVETIFENRFMHVQELNRLGANITIDGKTALVNGVEKLSGAKVMATDLRASASLVIAGLCADGETLIDRIYHLDRGYDR
MESKLTAVGAKVRRIKGNQA

Sequences:

>Translated_420_residues
MDKLVIEGGQKLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPDLQDVRTTLKLLGQMGVRTESADGKVSLDASKVDN
LVAPYELVKTMRASILVLGPLVARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEINIEHGFIEARAKRLKGARIITDM
ITVTGTENLLMAAVLADGETIIENAAREPEVGDLASLLVSMGAKIEGIGTDRLVIQGVDKLHGAKHTVVPDRIEAGTFLC
AVAAAGGDVTLRHVRPQILEAVTDKLRDAGVTIEEGDDWMRVRMNQRPKAVSFRTSEYPAFPTDMQAQFMALNTLAEGTS
QVVETIFENRFMHVQELNRLGANITIDGKTALVNGVEKLSGAKVMATDLRASASLVIAGLCADGETLIDRIYHLDRGYDR
MESKLTAVGAKVRRIKGNQA
>Mature_420_residues
MDKLVIEGGQKLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPDLQDVRTTLKLLGQMGVRTESADGKVSLDASKVDN
LVAPYELVKTMRASILVLGPLVARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEINIEHGFIEARAKRLKGARIITDM
ITVTGTENLLMAAVLADGETIIENAAREPEVGDLASLLVSMGAKIEGIGTDRLVIQGVDKLHGAKHTVVPDRIEAGTFLC
AVAAAGGDVTLRHVRPQILEAVTDKLRDAGVTIEEGDDWMRVRMNQRPKAVSFRTSEYPAFPTDMQAQFMALNTLAEGTS
QVVETIFENRFMHVQELNRLGANITIDGKTALVNGVEKLSGAKVMATDLRASASLVIAGLCADGETLIDRIYHLDRGYDR
MESKLTAVGAKVRRIKGNQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=58.9498806682578, Blast_Score=502, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BURP8 (B2JHY7)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858979.1
- ProteinModelPortal:   B2JHY7
- SMR:   B2JHY7
- GeneID:   6244244
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2761
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44809; Mature: 44809

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLVIEGGQKLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPDLQDVRTTLKLLGQM
CCCEEECCCCHHCCHHEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
GVRTESADGKVSLDASKVDNLVAPYELVKTMRASILVLGPLVARFGEAKVSLPGGCAIGA
CCCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEINIEHGFIEARAKRLKGARIITDMITVTGTENLLMAAVLADGET
CCHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCEEEHHHEECCCCHHHHHHHHCCCHH
IIENAAREPEVGDLASLLVSMGAKIEGIGTDRLVIQGVDKLHGAKHTVVPDRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHCCCCEECCCCCHHEEECHHHHCCCCCCCCCCCCCCCCEEE
AVAAAGGDVTLRHVRPQILEAVTDKLRDAGVTIEEGDDWMRVRMNQRPKAVSFRTSEYPA
EEEECCCCEEEHHHCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEEECCCCCC
FPTDMQAQFMALNTLAEGTSQVVETIFENRFMHVQELNRLGANITIDGKTALVNGVEKLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAKVMATDLRASASLVIAGLCADGETLIDRIYHLDRGYDRMESKLTAVGAKVRRIKGNQA
CCEEEEHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDKLVIEGGQKLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPDLQDVRTTLKLLGQM
CCCEEECCCCHHCCHHEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
GVRTESADGKVSLDASKVDNLVAPYELVKTMRASILVLGPLVARFGEAKVSLPGGCAIGA
CCCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEINIEHGFIEARAKRLKGARIITDMITVTGTENLLMAAVLADGET
CCHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCEEEHHHEECCCCHHHHHHHHCCCHH
IIENAAREPEVGDLASLLVSMGAKIEGIGTDRLVIQGVDKLHGAKHTVVPDRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHCCCCEECCCCCHHEEECHHHHCCCCCCCCCCCCCCCCEEE
AVAAAGGDVTLRHVRPQILEAVTDKLRDAGVTIEEGDDWMRVRMNQRPKAVSFRTSEYPA
EEEECCCCEEEHHHCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCEEEEECCCCCC
FPTDMQAQFMALNTLAEGTSQVVETIFENRFMHVQELNRLGANITIDGKTALVNGVEKLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAKVMATDLRASASLVIAGLCADGETLIDRIYHLDRGYDRMESKLTAVGAKVRRIKGNQA
CCEEEEHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA