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The map label for this gene is ruvA [H]

Identifier: 186477304

GI number: 186477304

Start: 2877902

End: 2878483

Strand: Direct

Name: ruvA [H]

Synonym: Bphy_2556

Alternate gene names: 186477304

Gene position: 2877902-2878483 (Clockwise)

Preceding gene: 186477302

Following gene: 186477305

Centisome position: 82.72

GC content: 61.0

Gene sequence:

>582_bases
ATGATCGGTCGCATCGCCGGCGTCCTGCTGGAAAAGAACCCGCCTCACCTGCTGATCGACTGCAACGGCGTCGGCTACGA
AGTCGACGTACCGATGAGCACGTTCTACAACCTGCCTGGAACGGGCGAAAAGGTCGTGCTGCTCACGCAGATGATCGTGC
GCGAAGACGCGCATCTGCTGTATGGCTTTCTCACGCCGCAAGAGCGTTCGACGTTTCGCGAGTTGTTAAAGATCACGGGT
ATCGGCGCGCGCATGGCGCTGGCCGTACTGTCTGGTATGAGCGTTCAGGAGCTGTCGCAGACGGTCACGATGCAGGATGC
CGCGCGTCTCACGCGTGTTCCGGGCATCGGCAAAAAGACGGCGGAACGGCTCCTGCTCGAACTGAAGGGCAAGCTCGGTG
CCGACCTCGGTGCAATGGCGGGTGCCGCGTCGCAGTCCGATCATGCTTCCGACATCCTGAATGCATTGCTGGCATTGGGT
TACTCCGAAAAAGAAGGGCTGGCGGCCATCAAGAACGTGCCGGCGGGCACAGGCGTTTCCGAGGGCATCAAGCTCGCGTT
GAAGGCGCTGTCGAAGGCCTGA

Upstream 100 bases:

>100_bases
GGCCGAGTCAATCAGCCGCTCTCCCACTTTGTCAGAAGCGACGTACGAAAGCACTCTGCCCTGCGCTACACTCGCGCTTT
CCCTATCGATAGAACCCGCC

Downstream 100 bases:

>100_bases
ATTGGCCCTCGGCAAACGGCTTGCATGAAGCTTCGCATGCCGTTTCCTGCGCGACACCCTGGCCGTTCGGCCAGGTCTTC
GAATGGGCCACGCGCGGTAC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPGTGEKVVLLTQMIVREDAHLLYGFLTPQERSTFRELLKITG
IGARMALAVLSGMSVQELSQTVTMQDAARLTRVPGIGKKTAERLLLELKGKLGADLGAMAGAASQSDHASDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA

Sequences:

>Translated_193_residues
MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPGTGEKVVLLTQMIVREDAHLLYGFLTPQERSTFRELLKITG
IGARMALAVLSGMSVQELSQTVTMQDAARLTRVPGIGKKTAERLLLELKGKLGADLGAMAGAASQSDHASDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA
>Mature_193_residues
MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPGTGEKVVLLTQMIVREDAHLLYGFLTPQERSTFRELLKITG
IGARMALAVLSGMSVQELSQTVTMQDAARLTRVPGIGKKTAERLLLELKGKLGADLGAMAGAASQSDHASDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=43.2835820895522, Blast_Score=168, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20354; Mature: 20354

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPGTGEKVVLLTQMIVREDAHLL
CCCHHHHHEECCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCHHE
YGFLTPQERSTFRELLKITGIGARMALAVLSGMSVQELSQTVTMQDAARLTRVPGIGKKT
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGAMAGAASQSDHASDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKA
HHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIAGVLLEKNPPHLLIDCNGVGYEVDVPMSTFYNLPGTGEKVVLLTQMIVREDAHLL
CCCHHHHHEECCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHCCCHHE
YGFLTPQERSTFRELLKITGIGARMALAVLSGMSVQELSQTVTMQDAARLTRVPGIGKKT
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGAMAGAASQSDHASDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA