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The map label for this gene is hrcA

Identifier: 186477252

GI number: 186477252

Start: 2813957

End: 2814976

Strand: Reverse

Name: hrcA

Synonym: Bphy_2503

Alternate gene names: 186477252

Gene position: 2814976-2813957 (Counterclockwise)

Preceding gene: 186477255

Following gene: 186477251

Centisome position: 80.91

GC content: 62.25

Gene sequence:

>1020_bases
ATGCTAGATCCTCGCGCACAAACCCTCCTCAAAACGCTGATCGAGCGGTATATCGCCGAAGGTCAGCCGGTCGGCTCGCG
CACGTTGTCGCGGTACTCCGGGCTCGAACTCAGCCCGGCGACGATCCGCAACGTGATGTCCGATCTGGAGGAACTGGGGC
TCGTCATCAGTCCGCATACGTCGGCGGGGCGCATTCCCACGCCGCGAGGCTACCGGCTCTTTGTCGACACCATGCTGACC
GTCGAGCCTTCCGCCGACGAGGACGCCGTGATGCGCGCGGTCAAAACCACACTGCAGCCGGGCGAGCCGCAGAAGGTGGT
GGCGGCGGCGGCCAGCGTGCTGTCCAACCTGTCGCAGTTCGCGGGCGTGATATTGACGCCGCGCCGCAGCCACGTGTTCA
AGCAGATCGAATTCCTGCGCCTGTCCGACAAACGCATCCTGCTGATCATCGTGACGCCGGAAGGCGATGTGCAGAACCGG
ATCATGGCGACGCAGCGCGACTTCACGCCGTCGCAACTGGTCGAAGCATCCAATTACATCAACGCACACTTCGCGGGGCT
GTCGTTCGACGAAGTGCGCCGGCGCCTGCGCGAGGAAATCGACGAACTTCGCGGCGACATGACCACGTTGATGCACGCGG
CCGTCACGGCGAGCACGGACGTCACGGACACGGGCGAAACCGTGCTGATTTCCGGCGAGCGCAAGCTGCTCGAAGTGGCC
GATCTTTCGTCGGACATGGCGCGGCTGCGCAAGCTTTTCGATGTATTCGATCAAAAGACAAGCCTCCTTCAGTTGCTCGA
CGTGTCGAGTCACGCGCAAGGCGTGCAGATTTTCATTGGCGGCGAGTCGAACCTCGTTCCCATTGAAGAAATGAGCGTGG
TGACTGCGCCGTACGAAGTGAACGGCAAGATTGTCGGCACGCTCGGGGTGATCGGACCGACGCGCATGGCGTACAACCGC
GTGATTCCCATTGTCGACATCACCGCGCGCCTGCTTTCGATGACCCTCAGCCAGCAGTAG

Upstream 100 bases:

>100_bases
GGCGGGGTGCCGCGCAGGGCGCGCCGGGCGACGAAGCCGCCTGCCAGCGCTCCGCCGCGTGCTCGTCGCCCTGTGGTGGT
TACGCTAAAATTTTTTCGCC

Downstream 100 bases:

>100_bases
CCCGGAAGCAGCGCAACGCCGCGACGAGTTCATCATGCGCGGCGTTTTTCGCCGTGCCAATTGGCCGAACGGCCAGGTAT
CGCCGGCAGACCGCGCCGCT

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVISPHTSAGRIPTPRGYRLFVDTMLT
VEPSADEDAVMRAVKTTLQPGEPQKVVAAAASVLSNLSQFAGVILTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNR
IMATQRDFTPSQLVEASNYINAHFAGLSFDEVRRRLREEIDELRGDMTTLMHAAVTASTDVTDTGETVLISGERKLLEVA
DLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESNLVPIEEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNR
VIPIVDITARLLSMTLSQQ

Sequences:

>Translated_339_residues
MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVISPHTSAGRIPTPRGYRLFVDTMLT
VEPSADEDAVMRAVKTTLQPGEPQKVVAAAASVLSNLSQFAGVILTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNR
IMATQRDFTPSQLVEASNYINAHFAGLSFDEVRRRLREEIDELRGDMTTLMHAAVTASTDVTDTGETVLISGERKLLEVA
DLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESNLVPIEEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNR
VIPIVDITARLLSMTLSQQ
>Mature_339_residues
MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVISPHTSAGRIPTPRGYRLFVDTMLT
VEPSADEDAVMRAVKTTLQPGEPQKVVAAAASVLSNLSQFAGVILTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNR
IMATQRDFTPSQLVEASNYINAHFAGLSFDEVRRRLREEIDELRGDMTTLMHAAVTASTDVTDTGETVLISGERKLLEVA
DLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESNLVPIEEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNR
VIPIVDITARLLSMTLSQQ

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BURP8 (B2JGE8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858722.1
- ProteinModelPortal:   B2JGE8
- SMR:   B2JGE8
- GeneID:   6243987
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2503
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37317; Mature: 37317

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVISPHT
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRIPTPRGYRLFVDTMLTVEPSADEDAVMRAVKTTLQPGEPQKVVAAAASVLSNLSQF
CCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AGVILTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRIMATQRDFTPSQLVEASNYI
CCEEECCCHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCC
NAHFAGLSFDEVRRRLREEIDELRGDMTTLMHAAVTASTDVTDTGETVLISGERKLLEVA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHH
DLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESNLVPIEEMSVVTAPYEV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCEEEECCEEE
NGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSMTLSQQ
CCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDPRAQTLLKTLIERYIAEGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVISPHT
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRIPTPRGYRLFVDTMLTVEPSADEDAVMRAVKTTLQPGEPQKVVAAAASVLSNLSQF
CCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AGVILTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRIMATQRDFTPSQLVEASNYI
CCEEECCCHHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCC
NAHFAGLSFDEVRRRLREEIDELRGDMTTLMHAAVTASTDVTDTGETVLISGERKLLEVA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHH
DLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESNLVPIEEMSVVTAPYEV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCEEEECCEEE
NGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSMTLSQQ
CCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA