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The map label for this gene is ywtG [H]

Identifier: 186477230

GI number: 186477230

Start: 2789759

End: 2791249

Strand: Direct

Name: ywtG [H]

Synonym: Bphy_2481

Alternate gene names: 186477230

Gene position: 2789759-2791249 (Clockwise)

Preceding gene: 186477229

Following gene: 186477231

Centisome position: 80.18

GC content: 66.93

Gene sequence:

>1491_bases
ATGTCCACTCTTCTCGCGCCCGAAGCAGGCGTCGCGCAGGCATCGTCCCGCGCCGATAACAAGCCCGTCATCCGCTCCGC
CGCCGACGTCTCGGCACTCGTCAACCAGGGCGCCGCCGTCGGCAGCGACGCGCGCATCGTCGTCGCGATCGCACTGGGCG
GCGTCTTCCTCGATGCCTACGATCTCGGCGCGCTCGCGTTCGGCCTCAAGGACGTGGCGCGCGAATTCTCGCTGACGCCC
GCCGGCACGGGCTTCGTCGCTTCGGCGATCACGTTCGGCGCGATCGTCGGCGCGTGTCTCGGCGGTTTTCTGACCGATCG
CCTCGGCCGCTATCGCGTGTTCATGGCCGACATGTTCTTCTTCGTGATCGCCGCGCTCGCCTGCGCGTTCGCGCCGAACG
CCTGGGTGCTCGGCGGCGCACGCTTCGTGATGGGACTGGGCGTCGGCATCGACCTGCCTGTCGCGATGGCGTTTCTCGCC
GAGTTCTCGCGCCTGCAGGGCAAGGGCAACAAGGCCGCTCGCGTGGCGATGTGGTGTCCCGTCTGGTACGCGGCCATCAG
CGTGTCGTATCTGCTGGTGCTCGCGTTCTACGCGACGCTGCCGGAAACCCACCAGCCTCTGCTATGGCGTCTGATTCTCG
GCTTTGGCGCCGTGCCCGCCATCGTCATCATCGCGATCCGCAGCCGCTATATCAGCGAATCGCCTGTCTGGGCCGCGAAT
CAGGGCGATCTTACGGGCGCTGCGCAGATCCTGAGGCGCTCATATGGTATCGACGCCGACGTCGCGCCGGATGCCGCCGC
TGCCGCACAACGCAGCCACGTGCGTACGGCATCGTGGAAAAACTACGGCACGCTGCTCAAGGGCGTCTATCTGAAGCGCA
CGGTGCTCGCGACGGTGATCGCAATCGCTTCGTCGTTCGCCTATAACGCGGTCGCGTTCGGTCTGCCCGTCATCATTTCC
AGCTTCCTCGCGCAGTCGATGCTCACGACGATCCTCGCATCGCTCGTGCTCAATCTCGCGTTCGCATTCGTGGGCGGCAT
TATCGCGGTGCGCACGGTGCCGAAGGTCGGCGCCTGGAAGCTGACGGTGCTCGGCTACGCTTGCCAGCTCGTCGCGCTGG
TGGGCCTTGCCGTCGTCGGCAAACCGGCGGGCGGCGCGCAGGTCGCCGTCGCGATCGCAATGCTCGCGCTGTTCCTGTTC
GGCCAGGGTTTCGGGCCGGGCTCGCATAGCATGACGTTCGCGTCGCTGAGCTATCCGACTTCGCTGCGCGGCGTCGGTGT
CGGCTTCAACCAGACGCTGATGCGCGCCAGTTCCACGGTTTCGCTGTTCCTCTTCCCCGTGCTCGCGGCCGCGCTGCATA
CGCGCGTGTTCTGGATCATCGCGGCCGCGCCGCTGTGCGGCCTCGTCGCGCTGCTGGCAATCCGCTGGGAGCCGTCGGGT
TACGACGTCGACGCCGAAGACTTCGCACCCGCCGCGGCAGCTAGACCGTAA

Upstream 100 bases:

>100_bases
ATGACGGCGAGCATGAGCTAATAACAAAAATAACGTTGATTGCGGCAACTGGGCGCCAGTACGATCCGCCCTTTTGCGCG
TTTTTGCGCGCACACGCCGC

Downstream 100 bases:

>100_bases
AGGCCTCGCTCCGGCGAGACGTCCGCTGACGTCGTTGTGACATCGGGGGTCTCCGGGCAACGGGAGACCCTCTTTTGCAT
TTTGGCGCGCCGCGCGGCGT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSTLLAPEAGVAQASSRADNKPVIRSAADVSALVNQGAAVGSDARIVVAIALGGVFLDAYDLGALAFGLKDVAREFSLTP
AGTGFVASAITFGAIVGACLGGFLTDRLGRYRVFMADMFFFVIAALACAFAPNAWVLGGARFVMGLGVGIDLPVAMAFLA
EFSRLQGKGNKAARVAMWCPVWYAAISVSYLLVLAFYATLPETHQPLLWRLILGFGAVPAIVIIAIRSRYISESPVWAAN
QGDLTGAAQILRRSYGIDADVAPDAAAAAQRSHVRTASWKNYGTLLKGVYLKRTVLATVIAIASSFAYNAVAFGLPVIIS
SFLAQSMLTTILASLVLNLAFAFVGGIIAVRTVPKVGAWKLTVLGYACQLVALVGLAVVGKPAGGAQVAVAIAMLALFLF
GQGFGPGSHSMTFASLSYPTSLRGVGVGFNQTLMRASSTVSLFLFPVLAAALHTRVFWIIAAAPLCGLVALLAIRWEPSG
YDVDAEDFAPAAAARP

Sequences:

>Translated_496_residues
MSTLLAPEAGVAQASSRADNKPVIRSAADVSALVNQGAAVGSDARIVVAIALGGVFLDAYDLGALAFGLKDVAREFSLTP
AGTGFVASAITFGAIVGACLGGFLTDRLGRYRVFMADMFFFVIAALACAFAPNAWVLGGARFVMGLGVGIDLPVAMAFLA
EFSRLQGKGNKAARVAMWCPVWYAAISVSYLLVLAFYATLPETHQPLLWRLILGFGAVPAIVIIAIRSRYISESPVWAAN
QGDLTGAAQILRRSYGIDADVAPDAAAAAQRSHVRTASWKNYGTLLKGVYLKRTVLATVIAIASSFAYNAVAFGLPVIIS
SFLAQSMLTTILASLVLNLAFAFVGGIIAVRTVPKVGAWKLTVLGYACQLVALVGLAVVGKPAGGAQVAVAIAMLALFLF
GQGFGPGSHSMTFASLSYPTSLRGVGVGFNQTLMRASSTVSLFLFPVLAAALHTRVFWIIAAAPLCGLVALLAIRWEPSG
YDVDAEDFAPAAAARP
>Mature_495_residues
STLLAPEAGVAQASSRADNKPVIRSAADVSALVNQGAAVGSDARIVVAIALGGVFLDAYDLGALAFGLKDVAREFSLTPA
GTGFVASAITFGAIVGACLGGFLTDRLGRYRVFMADMFFFVIAALACAFAPNAWVLGGARFVMGLGVGIDLPVAMAFLAE
FSRLQGKGNKAARVAMWCPVWYAAISVSYLLVLAFYATLPETHQPLLWRLILGFGAVPAIVIIAIRSRYISESPVWAANQ
GDLTGAAQILRRSYGIDADVAPDAAAAAQRSHVRTASWKNYGTLLKGVYLKRTVLATVIAIASSFAYNAVAFGLPVIISS
FLAQSMLTTILASLVLNLAFAFVGGIIAVRTVPKVGAWKLTVLGYACQLVALVGLAVVGKPAGGAQVAVAIAMLALFLFG
QGFGPGSHSMTFASLSYPTSLRGVGVGFNQTLMRASSTVSLFLFPVLAAALHTRVFWIIAAAPLCGLVALLAIRWEPSGY
DVDAEDFAPAAAARP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788068, Length=239, Percent_Identity=29.7071129707113, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082159, Length=402, Percent_Identity=26.3681592039801, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789207, Length=314, Percent_Identity=27.7070063694268, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786229, Length=395, Percent_Identity=22.7848101265823, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788074, Length=348, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789312, Length=442, Percent_Identity=25.7918552036199, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=341, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320705, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324469, Length=454, Percent_Identity=21.8061674008811, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR003663
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51635; Mature: 51504

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLAPEAGVAQASSRADNKPVIRSAADVSALVNQGAAVGSDARIVVAIALGGVFLDAY
CCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHH
DLGALAFGLKDVAREFSLTPAGTGFVASAITFGAIVGACLGGFLTDRLGRYRVFMADMFF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVIAALACAFAPNAWVLGGARFVMGLGVGIDLPVAMAFLAEFSRLQGKGNKAARVAMWCP
HHHHHHHHHCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHH
VWYAAISVSYLLVLAFYATLPETHQPLLWRLILGFGAVPAIVIIAIRSRYISESPVWAAN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCC
QGDLTGAAQILRRSYGIDADVAPDAAAAAQRSHVRTASWKNYGTLLKGVYLKRTVLATVI
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIASSFAYNAVAFGLPVIISSFLAQSMLTTILASLVLNLAFAFVGGIIAVRTVPKVGAWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LTVLGYACQLVALVGLAVVGKPAGGAQVAVAIAMLALFLFGQGFGPGSHSMTFASLSYPT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
SLRGVGVGFNQTLMRASSTVSLFLFPVLAAALHTRVFWIIAAAPLCGLVALLAIRWEPSG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
YDVDAEDFAPAAAARP
CCCCHHHCCCCCCCCC
>Mature Secondary Structure 
STLLAPEAGVAQASSRADNKPVIRSAADVSALVNQGAAVGSDARIVVAIALGGVFLDAY
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHH
DLGALAFGLKDVAREFSLTPAGTGFVASAITFGAIVGACLGGFLTDRLGRYRVFMADMFF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVIAALACAFAPNAWVLGGARFVMGLGVGIDLPVAMAFLAEFSRLQGKGNKAARVAMWCP
HHHHHHHHHCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHH
VWYAAISVSYLLVLAFYATLPETHQPLLWRLILGFGAVPAIVIIAIRSRYISESPVWAAN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCC
QGDLTGAAQILRRSYGIDADVAPDAAAAAQRSHVRTASWKNYGTLLKGVYLKRTVLATVI
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIASSFAYNAVAFGLPVIISSFLAQSMLTTILASLVLNLAFAFVGGIIAVRTVPKVGAWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LTVLGYACQLVALVGLAVVGKPAGGAQVAVAIAMLALFLFGQGFGPGSHSMTFASLSYPT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
SLRGVGVGFNQTLMRASSTVSLFLFPVLAAALHTRVFWIIAAAPLCGLVALLAIRWEPSG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
YDVDAEDFAPAAAARP
CCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]