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The map label for this gene is nahR [H]

Identifier: 186477170

GI number: 186477170

Start: 2720232

End: 2721260

Strand: Direct

Name: nahR [H]

Synonym: Bphy_2419

Alternate gene names: 186477170

Gene position: 2720232-2721260 (Clockwise)

Preceding gene: 186477169

Following gene: 186477174

Centisome position: 78.19

GC content: 66.28

Gene sequence:

>1029_bases
ATGGACGAAGACACCGCCGCTTCACTCGATATCTGGCTCGTGCGCGTGCTGCGCACGCTGCTCGTCGAGCGCAGCGTCAC
GCAGACAGCACTTCGCCTGAACCAGACACAGCCCGCCATCAGCACTGCGCTGCGCAAGCTGCGCGAAACGCTGAACGATC
CGATTCTCGTGCGCGGCAAGTCGGGCATGGTGCCGACGGAATATGGCGAATCACTGCTCGCCGCCGCGCAGAAGGTGCTG
CGCGACGTCGACTTCGTCGCGACGCCGCACGGCGACTTCGACCCGGCACGCTCGCGGCGCACGTTCCGCATTGCCGCGCC
CGATTACCTGAACGACTTCTTCATGCCGACCGTGATCGCCCAGTTCCGCGAGACGGCGCCGCATGCGCGGCTCGAGATCG
AGTCGCTCGGTCCGCTTTTCGATCACACCTGTGCACTCGATGCGGGCGAACTCGATCTCGTCATCGGCAACTGGCCGAAG
CCCGACTTGCGCTTCGAGCGCAGCGATCTCTTCTCGGATACCGTCGTGTGCATGATGCGCGCCGATCATCCGCTGGCGAA
GGCGCCGCTCACGCGCGATGCGTATCTCGCCGCGCCGCATCTCGCGCCCGCGCATTACAGCGGCGCGCGCGGCGGCGCGA
TCGACACGGGCTTCGCGCGCGCGCGCGCGTCGCGCCGCATCGTCGCGACGTTGCCGTACTTCGGTCTCGTGCCGCAGGTG
CTGCTGCAATCGGATCTGATCTTTACGACGACGCGCCGCTTTGCACTTCACTATGCGGCGATGTTGCCGCTGGCCGTGGT
CGACGTACCGATTCCGTTTCCGCGCATCAAGTGTTATCAGATGTGGCATCCGCAACCGGACCGGCCAAGCGATATTGCAT
GGCTGCGCGGCCTGATGGCGCAGGTGTCGGACATGCTCGTGGCGAAGAAGCCGCGGCGCGCAAGGGCGGCGGCGAAGCAA
GCGACGGCGGAAAAAAAAGCGGGCGCAGCCAGTGTGCCCGCCGCGCCCGCTGGAGGAAGCGGTCAGTGA

Upstream 100 bases:

>100_bases
TGGCGCGGCGTCGAGCGCATGACGCCGCGCCACGCGCGATGCACCGCCTCACACAAGCATTCGAAATGCCTAGCATGGGC
CTCCCCCGCCCCGCCGATTC

Downstream 100 bases:

>100_bases
ATCACGCGCCGATCTGGTCCGCTTCCTGAGCGGATGCGAGATCGGCAAGCGAAATCTGCTGCGAACGCAGCTGCAGCAGT
TCCGCGCAGACGGCGATGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDEDTAASLDIWLVRVLRTLLVERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGESLLAAAQKVL
RDVDFVATPHGDFDPARSRRTFRIAAPDYLNDFFMPTVIAQFRETAPHARLEIESLGPLFDHTCALDAGELDLVIGNWPK
PDLRFERSDLFSDTVVCMMRADHPLAKAPLTRDAYLAAPHLAPAHYSGARGGAIDTGFARARASRRIVATLPYFGLVPQV
LLQSDLIFTTTRRFALHYAAMLPLAVVDVPIPFPRIKCYQMWHPQPDRPSDIAWLRGLMAQVSDMLVAKKPRRARAAAKQ
ATAEKKAGAASVPAAPAGGSGQ

Sequences:

>Translated_342_residues
MDEDTAASLDIWLVRVLRTLLVERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGESLLAAAQKVL
RDVDFVATPHGDFDPARSRRTFRIAAPDYLNDFFMPTVIAQFRETAPHARLEIESLGPLFDHTCALDAGELDLVIGNWPK
PDLRFERSDLFSDTVVCMMRADHPLAKAPLTRDAYLAAPHLAPAHYSGARGGAIDTGFARARASRRIVATLPYFGLVPQV
LLQSDLIFTTTRRFALHYAAMLPLAVVDVPIPFPRIKCYQMWHPQPDRPSDIAWLRGLMAQVSDMLVAKKPRRARAAAKQ
ATAEKKAGAASVPAAPAGGSGQ
>Mature_342_residues
MDEDTAASLDIWLVRVLRTLLVERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGESLLAAAQKVL
RDVDFVATPHGDFDPARSRRTFRIAAPDYLNDFFMPTVIAQFRETAPHARLEIESLGPLFDHTCALDAGELDLVIGNWPK
PDLRFERSDLFSDTVVCMMRADHPLAKAPLTRDAYLAAPHLAPAHYSGARGGAIDTGFARARASRRIVATLPYFGLVPQV
LLQSDLIFTTTRRFALHYAAMLPLAVVDVPIPFPRIKCYQMWHPQPDRPSDIAWLRGLMAQVSDMLVAKKPRRARAAAKQ
ATAEKKAGAASVPAAPAGGSGQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=23.5690235690236, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=26.1744966442953, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081766, Length=281, Percent_Identity=22.7758007117438, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37596; Mature: 37596

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEDTAASLDIWLVRVLRTLLVERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECC
SGMVPTEYGESLLAAAQKVLRDVDFVATPHGDFDPARSRRTFRIAAPDYLNDFFMPTVIA
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHH
QFRETAPHARLEIESLGPLFDHTCALDAGELDLVIGNWPKPDLRFERSDLFSDTVVCMMR
HHHHCCCCCEEEHHHCCCHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
ADHPLAKAPLTRDAYLAAPHLAPAHYSGARGGAIDTGFARARASRRIVATLPYFGLVPQV
CCCCHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHH
LLQSDLIFTTTRRFALHYAAMLPLAVVDVPIPFPRIKCYQMWHPQPDRPSDIAWLRGLMA
HHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
QVSDMLVAKKPRRARAAAKQATAEKKAGAASVPAAPAGGSGQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEDTAASLDIWLVRVLRTLLVERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECC
SGMVPTEYGESLLAAAQKVLRDVDFVATPHGDFDPARSRRTFRIAAPDYLNDFFMPTVIA
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHH
QFRETAPHARLEIESLGPLFDHTCALDAGELDLVIGNWPKPDLRFERSDLFSDTVVCMMR
HHHHCCCCCEEEHHHCCCHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
ADHPLAKAPLTRDAYLAAPHLAPAHYSGARGGAIDTGFARARASRRIVATLPYFGLVPQV
CCCCHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHH
LLQSDLIFTTTRRFALHYAAMLPLAVVDVPIPFPRIKCYQMWHPQPDRPSDIAWLRGLMA
HHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
QVSDMLVAKKPRRARAAAKQATAEKKAGAASVPAAPAGGSGQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]