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The map label for this gene is potC [H]

Identifier: 186477131

GI number: 186477131

Start: 2673665

End: 2674504

Strand: Reverse

Name: potC [H]

Synonym: Bphy_2380

Alternate gene names: 186477131

Gene position: 2674504-2673665 (Counterclockwise)

Preceding gene: 186477132

Following gene: 186477130

Centisome position: 76.87

GC content: 57.26

Gene sequence:

>840_bases
ATGAAAACCAACGTTCCACGTTTCGCACCCTACATGTCGACGCCGGAAATTGTGTGGCACTACGTTCTGCGATCAGGCAA
TGTCATGGTTCTCCTGTTTCTGATCTTGCCGATACTGGCGATCATGCCACTTTCGTTTAACGAGAACTCATTCCTCGTTT
ATCCGATACACCAGTTTTCATTAAGGTGGTATCACAACCTCTTCACGGCTGTGGAATGGACGCGCGCCGGCGCCAATAGC
TTGATTGTGACGCCGATCGCGACGGTGCTCGCGACCGTCCTGGGCACGCTGGCGGCATTGGGACTGAACAAGGCGTCGTT
CAAGGGCAAGGGCGTGCTGGTCGCCGTTCTGATCTCGCCGATGATCGTGCCGGTGATCGTTACCGGCGTCGGAATGTATC
TGCAGTTTGCGCGATGGGGATTGTCTGGCACCTATGCCGGGCTGATTTTCGGGCACACGGTGATCGCCGCGCCGTTTGTC
GTGGTCACGGTCAACGCCACGCTTGCCGGCTTCAACCACAACTATGTACGGGCTAGCCTGAGCCTGGGCGCGTCGCCCGT
GCGGACGTTCTTCTCGGTCACATTGCCAATCATCGCCCCTGGCGTGATTTACGGAGCGTTGTTCGCGTTCGCGACCTCGC
TGGACGACGTCGTGATCACCATGTTCATTGCCGGCCCGACTCAGGGAACACTCCCGCTTCAGATGTTCATCGGGATTCGC
GAAAGCATCACGCCGACGATCGCCGCGCTTGCCTCAATTTTGATCGTCTTTTCGAGTCTGCTGCTCATTACGATGGAATG
GCTGCGTTCCAGATCAGTCGCGAGGCAGACGGCGAGTTGA

Upstream 100 bases:

>100_bases
ATGGCGTGTGCGCTTGGCGCGGTTCTCCTACTAGTGACGCTGATCCTGTTCAGCGTCTATCGAAGGGTCGTCGGTAAAGA
ACTGAAGGTGGCCTAGCATC

Downstream 100 bases:

>100_bases
CGATGTCGGGGATTGCGATCGTCGAACCGGCTTTCGAGGCCGCAGGCGTTGCGCAACAGAGTGAAATCGATATGCACAAC
AAGCAGGAGGCGTGATGTCA

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKTNVPRFAPYMSTPEIVWHYVLRSGNVMVLLFLILPILAIMPLSFNENSFLVYPIHQFSLRWYHNLFTAVEWTRAGANS
LIVTPIATVLATVLGTLAALGLNKASFKGKGVLVAVLISPMIVPVIVTGVGMYLQFARWGLSGTYAGLIFGHTVIAAPFV
VVTVNATLAGFNHNYVRASLSLGASPVRTFFSVTLPIIAPGVIYGALFAFATSLDDVVITMFIAGPTQGTLPLQMFIGIR
ESITPTIAALASILIVFSSLLLITMEWLRSRSVARQTAS

Sequences:

>Translated_279_residues
MKTNVPRFAPYMSTPEIVWHYVLRSGNVMVLLFLILPILAIMPLSFNENSFLVYPIHQFSLRWYHNLFTAVEWTRAGANS
LIVTPIATVLATVLGTLAALGLNKASFKGKGVLVAVLISPMIVPVIVTGVGMYLQFARWGLSGTYAGLIFGHTVIAAPFV
VVTVNATLAGFNHNYVRASLSLGASPVRTFFSVTLPIIAPGVIYGALFAFATSLDDVVITMFIAGPTQGTLPLQMFIGIR
ESITPTIAALASILIVFSSLLLITMEWLRSRSVARQTAS
>Mature_279_residues
MKTNVPRFAPYMSTPEIVWHYVLRSGNVMVLLFLILPILAIMPLSFNENSFLVYPIHQFSLRWYHNLFTAVEWTRAGANS
LIVTPIATVLATVLGTLAALGLNKASFKGKGVLVAVLISPMIVPVIVTGVGMYLQFARWGLSGTYAGLIFGHTVIAAPFV
VVTVNATLAGFNHNYVRASLSLGASPVRTFFSVTLPIIAPGVIYGALFAFATSLDDVVITMFIAGPTQGTLPLQMFIGIR
ESITPTIAALASILIVFSSLLLITMEWLRSRSVARQTAS

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=232, Percent_Identity=31.8965517241379, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787081, Length=230, Percent_Identity=32.6086956521739, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788764, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30162; Mature: 30162

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNVPRFAPYMSTPEIVWHYVLRSGNVMVLLFLILPILAIMPLSFNENSFLVYPIHQFS
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHH
LRWYHNLFTAVEWTRAGANSLIVTPIATVLATVLGTLAALGLNKASFKGKGVLVAVLISP
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
MIVPVIVTGVGMYLQFARWGLSGTYAGLIFGHTVIAAPFVVVTVNATLAGFNHNYVRASL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEHEEECCCCCCEEEEH
SLGASPVRTFFSVTLPIIAPGVIYGALFAFATSLDDVVITMFIAGPTQGTLPLQMFIGIR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHH
ESITPTIAALASILIVFSSLLLITMEWLRSRSVARQTAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTNVPRFAPYMSTPEIVWHYVLRSGNVMVLLFLILPILAIMPLSFNENSFLVYPIHQFS
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHH
LRWYHNLFTAVEWTRAGANSLIVTPIATVLATVLGTLAALGLNKASFKGKGVLVAVLISP
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
MIVPVIVTGVGMYLQFARWGLSGTYAGLIFGHTVIAAPFVVVTVNATLAGFNHNYVRASL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEHEEECCCCCCEEEEH
SLGASPVRTFFSVTLPIIAPGVIYGALFAFATSLDDVVITMFIAGPTQGTLPLQMFIGIR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHH
ESITPTIAALASILIVFSSLLLITMEWLRSRSVARQTAS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]