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The map label for this gene is acsAB [H]

Identifier: 186477128

GI number: 186477128

Start: 2668091

End: 2670241

Strand: Reverse

Name: acsAB [H]

Synonym: Bphy_2377

Alternate gene names: 186477128

Gene position: 2670241-2668091 (Counterclockwise)

Preceding gene: 186477130

Following gene: 186477127

Centisome position: 76.75

GC content: 57.14

Gene sequence:

>2151_bases
ATGAAAACACCGCTCATCGAGAAGCCGCCATTCTACGTGTCGGTCCTTGTCGTTGCGTACGTGCTCGCCGGCTTCCTGTA
TTTCGGCTGGCGTTTCACGACGATTAACTGGCAGTTGCCGCTGTTCTCGATTGCCTTGTATGTAGCGGAACTGTTTGGCT
TCGTTACGGGACTCCTGTATGCGCTGATGACCTACCGGCTCGCGGTGCGTGTGCCAGAGCAGCCGCTTTCCAATGCGAGC
GTGGACGTATTCGTTCCGACCTACAACGAATCGGTGGAACTCGTGCGCCGCACGTTGCTTGCCGCACGCAACATTGAATA
CCCGCATAAGACGTGGCTACTTGATGATGGAAATCGGATCGAAATGCGTGAACTCGCGGCGGAACTGGGCTGCGATTATC
TTGCCCGGGGCGAGAACGCACACGCCAAGGCAGGCAACCTGAACCATGCGTTGAAGCATAGCTCGGGCGAGTTTATTGCG
ATCTTCGATGCCGATCATGCGGCTCGTAAGGACTTTCTCACCAAGGTGATCGGCTTCTTCGCTGACCCACGTGTCGGATT
TGTACAAACGCCGCAGGATTTCTACAACGTCGACTCCTTTAGTCACAGGCAGATCGGACGACGCGTGTGGCACGAGCAAT
CGTTGTTCTTCAAGGTAATCCAGCGAGGCAAGGATAGCTGGAATGCCGCGTTTTTTTGCGGCAGTTGTGCGGTGTTGCGG
CGTTCGGCTCTTGAGCGCATCGGCGGCTTCGCCACCGAAACGGTCACCGAGGATATCCACACGTCAATCCTTCTGCATAA
GGCTGGGTACAAATCGGTCTATTACCCTGAATCGCTTGCATTCGGGCTCGCGCCGCACAGCCTGGACACATATCTTCAGC
AGCGTATCCGGTGGGGTGTCGGCGGTATGCAGGTGCTGCGACGGGAGCGCGTGCTGTGGAGCTCCGGCCTCACACTGGCA
CAGCGCCTCAATTACATGGCGTCGATGTTGATCTACTTCGAGGGATGGCAGAAGTTCGTCTTTTTCGTCACGCCTCCCAT
CGTGTTCTTCTTCGGGCTGCTGCCCATAGTTGCACCAATGGGGCAGTTCCTGGGGTGGTTCTTCCTGTACTACCTGCTTT
CAATGGCGATGTACCTCGAACTGGCACGCGGCTATGGAGCATTGCTTCTGAGCGAGCAGTACGGCATGTCTCGCTTTTTC
GCGTTCATGTCGACGACGACGGGCCTGTTCCGCAAGAGAACAAAATTTTCGGTTACGAGCAAGGAGTTGTCACTGGCTGG
CAAGGCATGGCTGTGGCTGTCCCCTTCGTTAATGGTCGCGGCGGTTACCTTGTTGAGCATTCCCGTCGGGATATACCGGA
TATGGGATGGCAGCCTGCCCGTTGGCGCCGGAATCGCCAACGCAGTATGGGCGCTGACGACAATAGCCACAGCAACCGTC
GTTGCATGGTTCAGCCATCGACGCGCACGCAATCGTCGCGCCGAATATCGCTTCCCGGTACATGTACCGATCACTCTGAA
ACTCGGACACTCAGAATGCCTCGGATTCACGGAGGATCTCTCGGCCGCGGGTGCCTTGTACAAAGGTGCCGTGCTGCACG
ACATATCGCAGCAGAGTTCAGTCGACGTGGTCGTCCATTTGCCCAACCTCGTCGTACCGGTGCCAGCAACAGTAACGTTC
ATCTGGCGAGAGGGCATGAAGCCGGGCGACCAGCCAGCACTCGGACTCCGTTTCAACTGGCCGAATGCGCAGGCGAGCGC
CCCGCTCGAACGCTTCCTGTTCGGCAGCAGCCTGCAATTCGATCTCGGACAAATGACGGACCAGCGTCCAACTTTCCTGG
CGCGTCTTTCTGGGCAGGCTGCGTATGCAGATAACACGCGCGGAGGCGATCCGCGTTGGAGTGCAGCACGAATCGACGCA
GGAAATCCGGGACAAGCGGTCCCGGTAGTGATCGCCGACGATGCGCACAACGGCGGCATTTTAATTATCAGTAACTGTTC
GCTGATGGAATCCACCGAAAGCGTCGAACTGCAAACTTTGGACGGAGCCGGAATCGATCGAAGACAAGTTCACCTGTCAC
CGGACGGTACTCTGGAAACACCCACCGGGCCCATGTATCTCTATAACGCAACGGCAGCCGCCAACGCATGA

Upstream 100 bases:

>100_bases
CCGATTTTCTATCGGTTACTTCAGCGTCTTGAAAGGGTGCCGTTAACAGATTACAGACGCTCCTCGTTCCCTCCGCTGTC
CATTTACGCATCGATTGACC

Downstream 100 bases:

>100_bases
ACGAAGCACGCACTAGAATGATTCAGATCAACGCTGTTCCCTCACGCCTCACGAGACCTTTCATCGCCGTCGCCAGTATT
CTCGCCGCTGCTCTCTTCAG

Product: cellulose synthase

Products: NA

Alternate protein names: Cellulose synthase catalytic domain [UDP-forming]; Cyclic di-GMP-binding domain; Cellulose synthase 1 regulatory domain [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MKTPLIEKPPFYVSVLVVAYVLAGFLYFGWRFTTINWQLPLFSIALYVAELFGFVTGLLYALMTYRLAVRVPEQPLSNAS
VDVFVPTYNESVELVRRTLLAARNIEYPHKTWLLDDGNRIEMRELAAELGCDYLARGENAHAKAGNLNHALKHSSGEFIA
IFDADHAARKDFLTKVIGFFADPRVGFVQTPQDFYNVDSFSHRQIGRRVWHEQSLFFKVIQRGKDSWNAAFFCGSCAVLR
RSALERIGGFATETVTEDIHTSILLHKAGYKSVYYPESLAFGLAPHSLDTYLQQRIRWGVGGMQVLRRERVLWSSGLTLA
QRLNYMASMLIYFEGWQKFVFFVTPPIVFFFGLLPIVAPMGQFLGWFFLYYLLSMAMYLELARGYGALLLSEQYGMSRFF
AFMSTTTGLFRKRTKFSVTSKELSLAGKAWLWLSPSLMVAAVTLLSIPVGIYRIWDGSLPVGAGIANAVWALTTIATATV
VAWFSHRRARNRRAEYRFPVHVPITLKLGHSECLGFTEDLSAAGALYKGAVLHDISQQSSVDVVVHLPNLVVPVPATVTF
IWREGMKPGDQPALGLRFNWPNAQASAPLERFLFGSSLQFDLGQMTDQRPTFLARLSGQAAYADNTRGGDPRWSAARIDA
GNPGQAVPVVIADDAHNGGILIISNCSLMESTESVELQTLDGAGIDRRQVHLSPDGTLETPTGPMYLYNATAAANA

Sequences:

>Translated_716_residues
MKTPLIEKPPFYVSVLVVAYVLAGFLYFGWRFTTINWQLPLFSIALYVAELFGFVTGLLYALMTYRLAVRVPEQPLSNAS
VDVFVPTYNESVELVRRTLLAARNIEYPHKTWLLDDGNRIEMRELAAELGCDYLARGENAHAKAGNLNHALKHSSGEFIA
IFDADHAARKDFLTKVIGFFADPRVGFVQTPQDFYNVDSFSHRQIGRRVWHEQSLFFKVIQRGKDSWNAAFFCGSCAVLR
RSALERIGGFATETVTEDIHTSILLHKAGYKSVYYPESLAFGLAPHSLDTYLQQRIRWGVGGMQVLRRERVLWSSGLTLA
QRLNYMASMLIYFEGWQKFVFFVTPPIVFFFGLLPIVAPMGQFLGWFFLYYLLSMAMYLELARGYGALLLSEQYGMSRFF
AFMSTTTGLFRKRTKFSVTSKELSLAGKAWLWLSPSLMVAAVTLLSIPVGIYRIWDGSLPVGAGIANAVWALTTIATATV
VAWFSHRRARNRRAEYRFPVHVPITLKLGHSECLGFTEDLSAAGALYKGAVLHDISQQSSVDVVVHLPNLVVPVPATVTF
IWREGMKPGDQPALGLRFNWPNAQASAPLERFLFGSSLQFDLGQMTDQRPTFLARLSGQAAYADNTRGGDPRWSAARIDA
GNPGQAVPVVIADDAHNGGILIISNCSLMESTESVELQTLDGAGIDRRQVHLSPDGTLETPTGPMYLYNATAAANA
>Mature_716_residues
MKTPLIEKPPFYVSVLVVAYVLAGFLYFGWRFTTINWQLPLFSIALYVAELFGFVTGLLYALMTYRLAVRVPEQPLSNAS
VDVFVPTYNESVELVRRTLLAARNIEYPHKTWLLDDGNRIEMRELAAELGCDYLARGENAHAKAGNLNHALKHSSGEFIA
IFDADHAARKDFLTKVIGFFADPRVGFVQTPQDFYNVDSFSHRQIGRRVWHEQSLFFKVIQRGKDSWNAAFFCGSCAVLR
RSALERIGGFATETVTEDIHTSILLHKAGYKSVYYPESLAFGLAPHSLDTYLQQRIRWGVGGMQVLRRERVLWSSGLTLA
QRLNYMASMLIYFEGWQKFVFFVTPPIVFFFGLLPIVAPMGQFLGWFFLYYLLSMAMYLELARGYGALLLSEQYGMSRFF
AFMSTTTGLFRKRTKFSVTSKELSLAGKAWLWLSPSLMVAAVTLLSIPVGIYRIWDGSLPVGAGIANAVWALTTIATATV
VAWFSHRRARNRRAEYRFPVHVPITLKLGHSECLGFTEDLSAAGALYKGAVLHDISQQSSVDVVVHLPNLVVPVPATVTF
IWREGMKPGDQPALGLRFNWPNAQASAPLERFLFGSSLQFDLGQMTDQRPTFLARLSGQAAYADNTRGGDPRWSAARIDA
GNPGQAVPVVIADDAHNGGILIISNCSLMESTESVELQTLDGAGIDRRQVHLSPDGTLETPTGPMYLYNATAAANA

Specific function: Bifunctional protein comprised of a catalytic subunit and a regulatory subunit. The catalytic subunit of cellulose synthase polymerizes uridine 5'-diphosphate glucose to cellulose in a processive way. The thick cellulosic mats generated by this enzyme pro

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=515, Percent_Identity=34.1747572815534, Blast_Score=273, Evalue=4e-74,
Organism=Escherichia coli, GI1787259, Length=248, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR003920
- InterPro:   IPR018513
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03170 BcsB; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 79767; Mature: 79767

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPLIEKPPFYVSVLVVAYVLAGFLYFGWRFTTINWQLPLFSIALYVAELFGFVTGLLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ALMTYRLAVRVPEQPLSNASVDVFVPTYNESVELVRRTLLAARNIEYPHKTWLLDDGNRI
HHHHHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEE
EMRELAAELGCDYLARGENAHAKAGNLNHALKHSSGEFIAIFDADHAARKDFLTKVIGFF
HHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
ADPRVGFVQTPQDFYNVDSFSHRQIGRRVWHEQSLFFKVIQRGKDSWNAAFFCGSCAVLR
CCCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
RSALERIGGFATETVTEDIHTSILLHKAGYKSVYYPESLAFGLAPHSLDTYLQQRIRWGV
HHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCEECCCHHHHCCCCHHHHHHHHHHHHHCC
GGMQVLRRERVLWSSGLTLAQRLNYMASMLIYFEGWQKFVFFVTPPIVFFFGLLPIVAPM
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
GQFLGWFFLYYLLSMAMYLELARGYGALLLSEQYGMSRFFAFMSTTTGLFRKRTKFSVTS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEECH
KELSLAGKAWLWLSPSLMVAAVTLLSIPVGIYRIWDGSLPVGAGIANAVWALTTIATATV
HHHHHCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
VAWFSHRRARNRRAEYRFPVHVPITLKLGHSECLGFTEDLSAAGALYKGAVLHDISQQSS
HHHHHHHHHHCCCCCEECEEEEEEEEEECCHHHCCCHHHHHHHHHHHHCHHHHHCCCCCC
VDVVVHLPNLVVPVPATVTFIWREGMKPGDQPALGLRFNWPNAQASAPLERFLFGSSLQF
CEEEEECCCEEEECCHHEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCC
DLGQMTDQRPTFLARLSGQAAYADNTRGGDPRWSAARIDAGNPGQAVPVVIADDAHNGGI
CHHHCCCCCCHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCE
LIISNCSLMESTESVELQTLDGAGIDRRQVHLSPDGTLETPTGPMYLYNATAAANA
EEEECCCHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MKTPLIEKPPFYVSVLVVAYVLAGFLYFGWRFTTINWQLPLFSIALYVAELFGFVTGLLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ALMTYRLAVRVPEQPLSNASVDVFVPTYNESVELVRRTLLAARNIEYPHKTWLLDDGNRI
HHHHHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEE
EMRELAAELGCDYLARGENAHAKAGNLNHALKHSSGEFIAIFDADHAARKDFLTKVIGFF
HHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
ADPRVGFVQTPQDFYNVDSFSHRQIGRRVWHEQSLFFKVIQRGKDSWNAAFFCGSCAVLR
CCCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
RSALERIGGFATETVTEDIHTSILLHKAGYKSVYYPESLAFGLAPHSLDTYLQQRIRWGV
HHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCEECCCHHHHCCCCHHHHHHHHHHHHHCC
GGMQVLRRERVLWSSGLTLAQRLNYMASMLIYFEGWQKFVFFVTPPIVFFFGLLPIVAPM
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
GQFLGWFFLYYLLSMAMYLELARGYGALLLSEQYGMSRFFAFMSTTTGLFRKRTKFSVTS
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEECH
KELSLAGKAWLWLSPSLMVAAVTLLSIPVGIYRIWDGSLPVGAGIANAVWALTTIATATV
HHHHHCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
VAWFSHRRARNRRAEYRFPVHVPITLKLGHSECLGFTEDLSAAGALYKGAVLHDISQQSS
HHHHHHHHHHCCCCCEECEEEEEEEEEECCHHHCCCHHHHHHHHHHHHCHHHHHCCCCCC
VDVVVHLPNLVVPVPATVTFIWREGMKPGDQPALGLRFNWPNAQASAPLERFLFGSSLQF
CEEEEECCCEEEECCHHEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCC
DLGQMTDQRPTFLARLSGQAAYADNTRGGDPRWSAARIDAGNPGQAVPVVIADDAHNGGI
CHHHCCCCCCHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCE
LIISNCSLMESTESVELQTLDGAGIDRRQVHLSPDGTLETPTGPMYLYNATAAANA
EEEECCCHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2151718; 1830823; 8083166; 8300521; 2138620; 11430986; 7883697 [H]