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The map label for this gene is qorA [H]

Identifier: 186477110

GI number: 186477110

Start: 2648440

End: 2649495

Strand: Reverse

Name: qorA [H]

Synonym: Bphy_2359

Alternate gene names: 186477110

Gene position: 2649495-2648440 (Counterclockwise)

Preceding gene: 186477113

Following gene: 186477108

Centisome position: 76.15

GC content: 60.51

Gene sequence:

>1056_bases
ATGAGGCACACGCGTATTATCGTGACTCGCTACGGTGGACCCGACGCACTCGCGGTCATTGAGGAGGAGTGCCCAGAGCC
GAAGGATGGCGAGGTGCGGGTCAAAGTCCTGACTGCAGGGGTCAGCTTGCCCGACCTCATGATGCGCGAGGGTATTCATC
CCGAAACGCCGCGCCTTCCTTTCACACCGGGCTGGGACCTGGTTGGCGTGGTGGATAGGCTCGGCAGCGGCGTCTCCGGA
ATAGAGTCCGGCCAGATAATTGCCGCGCTGCCGATCAGTGGTGCGTACGCGCAGTACGTGTGTCTGCATGAGCGCGAACT
GATTCCCGTGCCAGCGGGGTTGGATGCTGCCGAAGCTGTCAGCCTCGTGCTGAACTATGTCACGGCTTACCAGATGCTGC
ATCGTTCTGCGAAGGTCAGGCCTGGCCAGCGTGTATTGATCCACGGCGCGTCGGGCGGGGTCGGGTCGGCCCTTCTGCAA
CTTGGACGTCTCGCCGGACTGGAGATGTACGGTACCTGCTCATCGCGTGGAGCGTCCGCCGTGTCCGATCTGGGCGGTAT
CCCAATTGACTATCGACAGTCCGATTTTGTCGATGAAATTCATCGCCTCACAAAAGACGGCGTAGACGTCGTCTTTGACG
GGCTTGGCGGTTACCACATCTGGCGTTCCCGCAAGGCACTTCGTCCTGGCGGGACGGTCGTGGCATTTGGGCTAACTGCA
TCCCTGCGCGGAGGGCGATTGGCTTCAGGTCGTCCGGGCGGCCGTCATCGCTTTCGTGCGATCGCCGTTTTCGGGTTGTT
CATCGCTGGCGGCTGGCTTCTGCCGGGCAGAAAACGCGTGGTTCCCTACAGCATCCAGTGGCTCAAACGGCTGAAACCGG
CACAATTTCGACAGGATCTGATTGCACTGCTTGGACTTCTGCAACAGAGGAAGGTCAAGCCACTCATCGCACAACGCATT
CCCCTTGCTGAGGCGCGGCGCGCGCACGAACTGTTGGGAGATGGCGGCGTGTCAGGCAAAATCGTGCTCGTGTGCGATGA
ATCCCGTTCAGCATAA

Upstream 100 bases:

>100_bases
CCAGATGTGCAGCTGAGCTGCCAGGGGAGGTCACGTTAGTGCACTCACTGACGACAAGGTCGGGAGGTCGTGGGGTGACT
GTCGTGCGAGGATGGGGCTT

Downstream 100 bases:

>100_bases
GTAGCGCAATGCGAAGGGTACGTAGCAAAGGACAGCACGTGAGTCTTTGCTGATGCTGAGCCGGGCACGCGCATCTCAAG
AAAGGTTTCGACGACAGAAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRHTRIIVTRYGGPDALAVIEEECPEPKDGEVRVKVLTAGVSLPDLMMREGIHPETPRLPFTPGWDLVGVVDRLGSGVSG
IESGQIIAALPISGAYAQYVCLHERELIPVPAGLDAAEAVSLVLNYVTAYQMLHRSAKVRPGQRVLIHGASGGVGSALLQ
LGRLAGLEMYGTCSSRGASAVSDLGGIPIDYRQSDFVDEIHRLTKDGVDVVFDGLGGYHIWRSRKALRPGGTVVAFGLTA
SLRGGRLASGRPGGRHRFRAIAVFGLFIAGGWLLPGRKRVVPYSIQWLKRLKPAQFRQDLIALLGLLQQRKVKPLIAQRI
PLAEARRAHELLGDGGVSGKIVLVCDESRSA

Sequences:

>Translated_351_residues
MRHTRIIVTRYGGPDALAVIEEECPEPKDGEVRVKVLTAGVSLPDLMMREGIHPETPRLPFTPGWDLVGVVDRLGSGVSG
IESGQIIAALPISGAYAQYVCLHERELIPVPAGLDAAEAVSLVLNYVTAYQMLHRSAKVRPGQRVLIHGASGGVGSALLQ
LGRLAGLEMYGTCSSRGASAVSDLGGIPIDYRQSDFVDEIHRLTKDGVDVVFDGLGGYHIWRSRKALRPGGTVVAFGLTA
SLRGGRLASGRPGGRHRFRAIAVFGLFIAGGWLLPGRKRVVPYSIQWLKRLKPAQFRQDLIALLGLLQQRKVKPLIAQRI
PLAEARRAHELLGDGGVSGKIVLVCDESRSA
>Mature_351_residues
MRHTRIIVTRYGGPDALAVIEEECPEPKDGEVRVKVLTAGVSLPDLMMREGIHPETPRLPFTPGWDLVGVVDRLGSGVSG
IESGQIIAALPISGAYAQYVCLHERELIPVPAGLDAAEAVSLVLNYVTAYQMLHRSAKVRPGQRVLIHGASGGVGSALLQ
LGRLAGLEMYGTCSSRGASAVSDLGGIPIDYRQSDFVDEIHRLTKDGVDVVFDGLGGYHIWRSRKALRPGGTVVAFGLTA
SLRGGRLASGRPGGRHRFRAIAVFGLFIAGGWLLPGRKRVVPYSIQWLKRLKPAQFRQDLIALLGLLQQRKVKPLIAQRI
PLAEARRAHELLGDGGVSGKIVLVCDESRSA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=30.0578034682081, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI18379349, Length=317, Percent_Identity=31.5457413249211, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI194239674, Length=351, Percent_Identity=28.7749287749288, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI13236495, Length=351, Percent_Identity=28.7749287749288, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI194239676, Length=204, Percent_Identity=34.8039215686275, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=29.1666666666667, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=29.1666666666667, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI28557745, Length=242, Percent_Identity=28.9256198347107, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI67078404, Length=323, Percent_Identity=25.077399380805, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI67078406, Length=317, Percent_Identity=24.9211356466877, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI47519420, Length=210, Percent_Identity=29.0476190476191, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=347, Percent_Identity=27.6657060518732, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17507255, Length=345, Percent_Identity=27.536231884058, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71987554, Length=374, Percent_Identity=25.4010695187166, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536829, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=249, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=276, Percent_Identity=25.3623188405797, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550423, Length=242, Percent_Identity=29.7520661157025, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37760; Mature: 37760

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHTRIIVTRYGGPDALAVIEEECPEPKDGEVRVKVLTAGVSLPDLMMREGIHPETPRLP
CCCEEEEEEECCCCCCEEHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCC
FTPGWDLVGVVDRLGSGVSGIESGQIIAALPISGAYAQYVCLHERELIPVPAGLDAAEAV
CCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHEEEECCCCEEECCCCCCHHHHH
SLVLNYVTAYQMLHRSAKVRPGQRVLIHGASGGVGSALLQLGRLAGLEMYGTCSSRGASA
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHH
VSDLGGIPIDYRQSDFVDEIHRLTKDGVDVVFDGLGGYHIWRSRKALRPGGTVVAFGLTA
HHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEHHHCCCCCCCCCCEEEEEEEE
SLRGGRLASGRPGGRHRFRAIAVFGLFIAGGWLLPGRKRVVPYSIQWLKRLKPAQFRQDL
ECCCCEECCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHCCHHHHHHHH
IALLGLLQQRKVKPLIAQRIPLAEARRAHELLGDGGVSGKIVLVCDESRSA
HHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRHTRIIVTRYGGPDALAVIEEECPEPKDGEVRVKVLTAGVSLPDLMMREGIHPETPRLP
CCCEEEEEEECCCCCCEEHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCC
FTPGWDLVGVVDRLGSGVSGIESGQIIAALPISGAYAQYVCLHERELIPVPAGLDAAEAV
CCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHEEEECCCCEEECCCCCCHHHHH
SLVLNYVTAYQMLHRSAKVRPGQRVLIHGASGGVGSALLQLGRLAGLEMYGTCSSRGASA
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCHH
VSDLGGIPIDYRQSDFVDEIHRLTKDGVDVVFDGLGGYHIWRSRKALRPGGTVVAFGLTA
HHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEHHHCCCCCCCCCCEEEEEEEE
SLRGGRLASGRPGGRHRFRAIAVFGLFIAGGWLLPGRKRVVPYSIQWLKRLKPAQFRQDL
ECCCCEECCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHCCHHHHHHHH
IALLGLLQQRKVKPLIAQRIPLAEARRAHELLGDGGVSGKIVLVCDESRSA
HHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]