Click here to switch to the map view.

The map label for this gene is cysC [H]

Identifier: 186477083

GI number: 186477083

Start: 2615093

End: 2615752

Strand: Direct

Name: cysC [H]

Synonym: Bphy_2332

Alternate gene names: 186477083

Gene position: 2615093-2615752 (Clockwise)

Preceding gene: 186477082

Following gene: 186477086

Centisome position: 75.16

GC content: 61.52

Gene sequence:

>660_bases
GTGCCCAACAGTCGCCAGGCTCGCGATGAGCCGGAAAACCGCGCGCCCGTCGAACGCATACGGCCTCATGTCCAACGCTT
CAATGGCGCGATCACAGACCGCGACCGCGCGGCGCTGCTCGGCCACATGCCCGTCACCGTGTGGCTCACGGGTTTGTCGG
GCGCGGGGAAGTCAACCATCGCGTTTCATCTGGAGCGCGAACTGATGTCGATGGGGCACGCGTGTTATGTGCTCGATGGC
GACAACATCCGTCACGGTTTGACGAGCGACCTCGGCTTTTCGAAGGAAGATCGCCGGGAGAACATTCGCCGCGTCGCGCA
CGTCGCGCGACTGATGAACGACGCCGGGCTGATCGTGATTGCCGCGCTGATTTCGCCGATGCGCGAAGACCGGGAGATGG
CGTGCGCCATCATCGGCAATGACAGCTTTGTCGAGACTTATGTAGCCGCTTCAGCAAACGATTGCGCGAAACGCGACCCC
AAAGGGCTCTATGCGAAGGCGCAAGCAGGCATCATCGAATCGTTCACGGGTGTGACCGCGCCGTACGAACCACCGGAGAA
TCCCGAACTGCTCGTCGATACGGCGACGCTGACAGAAGCAGCCAGCGTATCGTGTGTGCTCGAATATTTGCGGGAACGCT
TTCTGGTGCTGCGACGCTGA

Upstream 100 bases:

>100_bases
TTTCTACGGCGGAAACAAACGGATAACCGAATTGGAACACCTCCGCCCCAGCGCTGCTGCTGGCGCTCCCGATGCGCGTG
CACGCTGCGTTCAAAGCAGC

Downstream 100 bases:

>100_bases
AGCCGTCGTGCACTAGCTCAATCGCTTGCTACAACCAGAGCACCAAAAGAAAAACCCGCATCGCTGCGGGTTTTTCTTTT
TTTGGCACGGGAAGCACGCT

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPNSRQARDEPENRAPVERIRPHVQRFNGAITDRDRAALLGHMPVTVWLTGLSGAGKSTIAFHLERELMSMGHACYVLDG
DNIRHGLTSDLGFSKEDRRENIRRVAHVARLMNDAGLIVIAALISPMREDREMACAIIGNDSFVETYVAASANDCAKRDP
KGLYAKAQAGIIESFTGVTAPYEPPENPELLVDTATLTEAASVSCVLEYLRERFLVLRR

Sequences:

>Translated_219_residues
MPNSRQARDEPENRAPVERIRPHVQRFNGAITDRDRAALLGHMPVTVWLTGLSGAGKSTIAFHLERELMSMGHACYVLDG
DNIRHGLTSDLGFSKEDRRENIRRVAHVARLMNDAGLIVIAALISPMREDREMACAIIGNDSFVETYVAASANDCAKRDP
KGLYAKAQAGIIESFTGVTAPYEPPENPELLVDTATLTEAASVSCVLEYLRERFLVLRR
>Mature_218_residues
PNSRQARDEPENRAPVERIRPHVQRFNGAITDRDRAALLGHMPVTVWLTGLSGAGKSTIAFHLERELMSMGHACYVLDGD
NIRHGLTSDLGFSKEDRRENIRRVAHVARLMNDAGLIVIAALISPMREDREMACAIIGNDSFVETYVAASANDCAKRDPK
GLYAKAQAGIIESFTGVTAPYEPPENPELLVDTATLTEAASVSCVLEYLRERFLVLRR

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI62912492, Length=178, Percent_Identity=51.685393258427, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI34447231, Length=178, Percent_Identity=51.685393258427, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI46094058, Length=178, Percent_Identity=51.123595505618, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1789107, Length=186, Percent_Identity=47.3118279569892, Blast_Score=173, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17542422, Length=192, Percent_Identity=51.0416666666667, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6322852, Length=182, Percent_Identity=46.1538461538462, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667032, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24667028, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24667036, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI116007838, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24667044, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24667040, Length=180, Percent_Identity=47.7777777777778, Blast_Score=164, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 24217; Mature: 24086

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSRQARDEPENRAPVERIRPHVQRFNGAITDRDRAALLGHMPVTVWLTGLSGAGKSTI
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHH
AFHLERELMSMGHACYVLDGDNIRHGLTSDLGFSKEDRRENIRRVAHVARLMNDAGLIVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
AALISPMREDREMACAIIGNDSFVETYVAASANDCAKRDPKGLYAKAQAGIIESFTGVTA
HHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCC
PYEPPENPELLVDTATLTEAASVSCVLEYLRERFLVLRR
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNSRQARDEPENRAPVERIRPHVQRFNGAITDRDRAALLGHMPVTVWLTGLSGAGKSTI
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHH
AFHLERELMSMGHACYVLDGDNIRHGLTSDLGFSKEDRRENIRRVAHVARLMNDAGLIVI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
AALISPMREDREMACAIIGNDSFVETYVAASANDCAKRDPKGLYAKAQAGIIESFTGVTA
HHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCC
PYEPPENPELLVDTATLTEAASVSCVLEYLRERFLVLRR
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA