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The map label for this gene is eryC1 [H]

Identifier: 186477059

GI number: 186477059

Start: 2593562

End: 2594659

Strand: Reverse

Name: eryC1 [H]

Synonym: Bphy_2308

Alternate gene names: 186477059

Gene position: 2594659-2593562 (Counterclockwise)

Preceding gene: 186477060

Following gene: 186477058

Centisome position: 74.58

GC content: 58.29

Gene sequence:

>1098_bases
GTGAAAGTGCCATTCCTTGATGTCCGCAGCGCCTATATTGAACTGAAGTCCGAGATCGATGAGGCCGTTTCTCGAGCGCT
CGACTCCGGCTGGTATATCTTCGGGGAAGAGGTCGCACGATTTGAAAAGTCGTTTGCCGACTACACCGGTACCCGTTTCG
CGATCGGCGTAGGCAATGGTCTCGATGCCCTGCGTATCGCCCTGATGGCGATGGGGGTGTCCGAAGGGGACGAAGTCATC
GTTCCTTCCAACACCTATATCGCGACGTGGCTCGCGGTAACGCAGTGCGGCGCACGTCCGGTGCCTGTCGAGCCCGACGC
AGACACGCTCAACATCGATCCGCGGCGCATCGAGCAGGCCATGACCAGTAAAACCAAGGTTATTCTGCCCGTGCATCTGT
ATGGACTGCCAGCTGAAATGGGTCCGATCCTCGAACTGGCGCGTCGCAAAGGTGTGCGAGTCCTCGAAGACGGCGCGCAG
GCACACGGTGCTCGCTACCGTGGTGAACTCATTGGCGGCCACGGCGATGCCGTCACGTGGAGTTTCTATCCTGGCAAAAA
TCTCGGCGCATTCGGTGATGCGGGCGGTGTGACGACCAACGATGCAGAGCTCGCTGAGCGGATCCGGACCATTGCGAACT
ACGGCTCGAAGGTGAAATACGTCAATGAGGTGTGTGGGGTGAATAGCAGGCTCGATCCGCTTCACGCCGCAGCACTGAAC
GTCAAACTGCCGCATCTGGAGGAGTGGAACAGGCGTCGCGTGAAAATCGCGGAGTACTACCAGCGTCACCTGCAGAACAC
GAGTGTGCGGGTTCCCGTTTCGCCTCCGGATTGCATGTCGTCATGGCATCTGTTCCCCGTCTTTTCGCAGCGGCGCGATG
CGTTACAGTCGAGGCTGAAGGAGGCCGGAATCGAGACGCTGATTCACTACCCGATTCCACCGCATCTGCAACAGGCGTAC
CACTTCCTCGGGTACGAAAAGGGCGACTTTCCTGTTGCCGAAGCAATGGCCGAGACCGAGTTGAGTCTGCCCATCGGCCC
CCATATGACGCCTGAACAAGCAGCGTATGTTTGTGAAATTATCGCGGGTTTCGAGTAA

Upstream 100 bases:

>100_bases
GGTGCGTTCTCGTTGAATTATCTTGCGAGTGGAGTGAGCGATGTCTGTTGCCGTGACATTGCCGCCGGAGTAAGTTTATT
CGAGAGTAAGGATCACAATT

Downstream 100 bases:

>100_bases
TGCAAGACTTTGATCTCGATCGATTGCATGAATCGGTCGCGAAATGCATTTCCCTATCGCAATACGACGACGCGATGGTG
CGCATCAAATCGTTCGTTGA

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKVPFLDVRSAYIELKSEIDEAVSRALDSGWYIFGEEVARFEKSFADYTGTRFAIGVGNGLDALRIALMAMGVSEGDEVI
VPSNTYIATWLAVTQCGARPVPVEPDADTLNIDPRRIEQAMTSKTKVILPVHLYGLPAEMGPILELARRKGVRVLEDGAQ
AHGARYRGELIGGHGDAVTWSFYPGKNLGAFGDAGGVTTNDAELAERIRTIANYGSKVKYVNEVCGVNSRLDPLHAAALN
VKLPHLEEWNRRRVKIAEYYQRHLQNTSVRVPVSPPDCMSSWHLFPVFSQRRDALQSRLKEAGIETLIHYPIPPHLQQAY
HFLGYEKGDFPVAEAMAETELSLPIGPHMTPEQAAYVCEIIAGFE

Sequences:

>Translated_365_residues
MKVPFLDVRSAYIELKSEIDEAVSRALDSGWYIFGEEVARFEKSFADYTGTRFAIGVGNGLDALRIALMAMGVSEGDEVI
VPSNTYIATWLAVTQCGARPVPVEPDADTLNIDPRRIEQAMTSKTKVILPVHLYGLPAEMGPILELARRKGVRVLEDGAQ
AHGARYRGELIGGHGDAVTWSFYPGKNLGAFGDAGGVTTNDAELAERIRTIANYGSKVKYVNEVCGVNSRLDPLHAAALN
VKLPHLEEWNRRRVKIAEYYQRHLQNTSVRVPVSPPDCMSSWHLFPVFSQRRDALQSRLKEAGIETLIHYPIPPHLQQAY
HFLGYEKGDFPVAEAMAETELSLPIGPHMTPEQAAYVCEIIAGFE
>Mature_365_residues
MKVPFLDVRSAYIELKSEIDEAVSRALDSGWYIFGEEVARFEKSFADYTGTRFAIGVGNGLDALRIALMAMGVSEGDEVI
VPSNTYIATWLAVTQCGARPVPVEPDADTLNIDPRRIEQAMTSKTKVILPVHLYGLPAEMGPILELARRKGVRVLEDGAQ
AHGARYRGELIGGHGDAVTWSFYPGKNLGAFGDAGGVTTNDAELAERIRTIANYGSKVKYVNEVCGVNSRLDPLHAAALN
VKLPHLEEWNRRRVKIAEYYQRHLQNTSVRVPVSPPDCMSSWHLFPVFSQRRDALQSRLKEAGIETLIHYPIPPHLQQAY
HFLGYEKGDFPVAEAMAETELSLPIGPHMTPEQAAYVCEIIAGFE

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=361, Percent_Identity=35.7340720221607, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI2367285, Length=305, Percent_Identity=32.4590163934426, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 40376; Mature: 40376

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPFLDVRSAYIELKSEIDEAVSRALDSGWYIFGEEVARFEKSFADYTGTRFAIGVGNG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCC
LDALRIALMAMGVSEGDEVIVPSNTYIATWLAVTQCGARPVPVEPDADTLNIDPRRIEQA
HHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHH
MTSKTKVILPVHLYGLPAEMGPILELARRKGVRVLEDGAQAHGARYRGELIGGHGDAVTW
HHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCEEECCCHHHCCCCCCCEEECCCCCEEEE
SFYPGKNLGAFGDAGGVTTNDAELAERIRTIANYGSKVKYVNEVCGVNSRLDPLHAAALN
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHEEE
VKLPHLEEWNRRRVKIAEYYQRHLQNTSVRVPVSPPDCMSSWHLFPVFSQRRDALQSRLK
EECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCEEHHHHHHHHHHHHHHH
EAGIETLIHYPIPPHLQQAYHFLGYEKGDFPVAEAMAETELSLPIGPHMTPEQAAYVCEI
HCCHHEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IAGFE
HHCCC
>Mature Secondary Structure
MKVPFLDVRSAYIELKSEIDEAVSRALDSGWYIFGEEVARFEKSFADYTGTRFAIGVGNG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCC
LDALRIALMAMGVSEGDEVIVPSNTYIATWLAVTQCGARPVPVEPDADTLNIDPRRIEQA
HHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHH
MTSKTKVILPVHLYGLPAEMGPILELARRKGVRVLEDGAQAHGARYRGELIGGHGDAVTW
HHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCEEECCCHHHCCCCCCCEEECCCCCEEEE
SFYPGKNLGAFGDAGGVTTNDAELAERIRTIANYGSKVKYVNEVCGVNSRLDPLHAAALN
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHEEE
VKLPHLEEWNRRRVKIAEYYQRHLQNTSVRVPVSPPDCMSSWHLFPVFSQRRDALQSRLK
EECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCEEHHHHHHHHHHHHHHH
EAGIETLIHYPIPPHLQQAYHFLGYEKGDFPVAEAMAETELSLPIGPHMTPEQAAYVCEI
HCCHHEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IAGFE
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]