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The map label for this gene is mdmB [H]

Identifier: 186477051

GI number: 186477051

Start: 2583062

End: 2584180

Strand: Reverse

Name: mdmB [H]

Synonym: Bphy_2300

Alternate gene names: 186477051

Gene position: 2584180-2583062 (Counterclockwise)

Preceding gene: 186477052

Following gene: 186477043

Centisome position: 74.28

GC content: 48.08

Gene sequence:

>1119_bases
ATGAAACTTGATAGTCTGACGGCACTTCGGTTTTTTGCGGCAGCTTCGATTGTTATTGAACATAGCAAGAACGCTTTTCG
TTCGATGGACTGGATTCCGCATTTTCACTATGACTTCGGTGTCAGTTTCTTCTTCGTGCTTTCGGGGTTCATCCTTACTT
ATACCTATCGCAACTTCGATAGTGCCGAAAGTGTGCGCCGCTTTTATGTCGCTCGCGTAGCCCGCGTATGGCCGTTGCAT
ATATTCATGCTCGGTACATTCCTCGTAGTGATTCCGCATCAAGGTTGGTTTTTTGGTGGAACGGATGCCCATCATGTAGT
AATCTTCCTGGCGAATTTTTTTCTGGTTCATGCCTGGCTCCCGATTATTGCGTTCTTCTTCAGTTTTAATGCGGTTTCGT
GGAGCATCTCTACTGAGGCATTTTTCTATCTGGTATTTCCAGTGTTACGTCATCGCTGGGAAAGTACATGGCATTGGAAG
TCCGGAATAGTTGCCCTTATCGCGTTTGGTGTGTTGGCTGTTGTAAACCCATACCGTATTTCGTTGGCTAATCCGCAAAC
GCCTCTAACGATATCCGCCGAAGGAATCGGCTACATTTCTCCGTTTGTGCGGGTAATAGAGTTTTTGCTTGGAATGTTGA
CGGCAACGGCTTTTGACGCAATCAGAAAGTGGCCACTGCCCAAAGGAGTGGCCTTCTGGACAGTGCTGGAAGTGTCCGCT
ATCGGCTTAATCGTTTTTATCGAAAGGCTCGCAGGCTACACTGCCACTTCGCCGTGGACCGTATTTACGGTTGAATGTAC
CGACGCACCCGCTTTCCCGCTGATGATTCTGGTATTTGCGTTCGGTAATGGGCTAATCTCAAAGCTCGTCTCTGTTCGCC
CCCTGGTCATTTTAGGAGAGGCGAGTTTTGCCCTATATTTATCTCATCTACTGTTGTTCAATGTGTTTGACAGCTATCGA
GGTAGCTTAGCGTTCTCCGATTTGACTCTCTGCATCGGATATTGGATAGCTGCAATAGCGATTTCACTTTTGCTGTGGAG
CTTCATCGAAAAGCCGGCGCGTACGCAAATCAGGAGGCTTGGTTCCAAAGAGAAGCCAGTCGCGGCCGGCACCATTTAG

Upstream 100 bases:

>100_bases
GTGGCGCAAATGCCAGGTGCGATTCGGTTACTCACCATTACCATATCTTGCAAGGTGGCGTACGGCATGCGTGTCTCAGG
CGCATGGGAGCTGAGTATGT

Downstream 100 bases:

>100_bases
CAGAGGCTCGTAAGGCGGTAGCTGACCAATGCATGAAATGCGGGCGCAGCCGGCCGCCGGACATCTGCCGGGTGGAGGTA
CTGGCCCGTGCTGCCTACGT

Product: acyltransferase 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKLDSLTALRFFAAASIVIEHSKNAFRSMDWIPHFHYDFGVSFFFVLSGFILTYTYRNFDSAESVRRFYVARVARVWPLH
IFMLGTFLVVIPHQGWFFGGTDAHHVVIFLANFFLVHAWLPIIAFFFSFNAVSWSISTEAFFYLVFPVLRHRWESTWHWK
SGIVALIAFGVLAVVNPYRISLANPQTPLTISAEGIGYISPFVRVIEFLLGMLTATAFDAIRKWPLPKGVAFWTVLEVSA
IGLIVFIERLAGYTATSPWTVFTVECTDAPAFPLMILVFAFGNGLISKLVSVRPLVILGEASFALYLSHLLLFNVFDSYR
GSLAFSDLTLCIGYWIAAIAISLLLWSFIEKPARTQIRRLGSKEKPVAAGTI

Sequences:

>Translated_372_residues
MKLDSLTALRFFAAASIVIEHSKNAFRSMDWIPHFHYDFGVSFFFVLSGFILTYTYRNFDSAESVRRFYVARVARVWPLH
IFMLGTFLVVIPHQGWFFGGTDAHHVVIFLANFFLVHAWLPIIAFFFSFNAVSWSISTEAFFYLVFPVLRHRWESTWHWK
SGIVALIAFGVLAVVNPYRISLANPQTPLTISAEGIGYISPFVRVIEFLLGMLTATAFDAIRKWPLPKGVAFWTVLEVSA
IGLIVFIERLAGYTATSPWTVFTVECTDAPAFPLMILVFAFGNGLISKLVSVRPLVILGEASFALYLSHLLLFNVFDSYR
GSLAFSDLTLCIGYWIAAIAISLLLWSFIEKPARTQIRRLGSKEKPVAAGTI
>Mature_372_residues
MKLDSLTALRFFAAASIVIEHSKNAFRSMDWIPHFHYDFGVSFFFVLSGFILTYTYRNFDSAESVRRFYVARVARVWPLH
IFMLGTFLVVIPHQGWFFGGTDAHHVVIFLANFFLVHAWLPIIAFFFSFNAVSWSISTEAFFYLVFPVLRHRWESTWHWK
SGIVALIAFGVLAVVNPYRISLANPQTPLTISAEGIGYISPFVRVIEFLLGMLTATAFDAIRKWPLPKGVAFWTVLEVSA
IGLIVFIERLAGYTATSPWTVFTVECTDAPAFPLMILVFAFGNGLISKLVSVRPLVILGEASFALYLSHLLLFNVFDSYR
GSLAFSDLTLCIGYWIAAIAISLLLWSFIEKPARTQIRRLGSKEKPVAAGTI

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 41969; Mature: 41969

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDSLTALRFFAAASIVIEHSKNAFRSMDWIPHFHYDFGVSFFFVLSGFILTYTYRNFD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SAESVRRFYVARVARVWPLHIFMLGTFLVVIPHQGWFFGGTDAHHVVIFLANFFLVHAWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCCCHHHHHHHHHHHHHHHHHH
PIIAFFFSFNAVSWSISTEAFFYLVFPVLRHRWESTWHWKSGIVALIAFGVLAVVNPYRI
HHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEE
SLANPQTPLTISAEGIGYISPFVRVIEFLLGMLTATAFDAIRKWPLPKGVAFWTVLEVSA
EECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IGLIVFIERLAGYTATSPWTVFTVECTDAPAFPLMILVFAFGNGLISKLVSVRPLVILGE
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCEEEECC
ASFALYLSHLLLFNVFDSYRGSLAFSDLTLCIGYWIAAIAISLLLWSFIEKPARTQIRRL
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GSKEKPVAAGTI
CCCCCCCCCCCC
>Mature Secondary Structure
MKLDSLTALRFFAAASIVIEHSKNAFRSMDWIPHFHYDFGVSFFFVLSGFILTYTYRNFD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SAESVRRFYVARVARVWPLHIFMLGTFLVVIPHQGWFFGGTDAHHVVIFLANFFLVHAWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCCCHHHHHHHHHHHHHHHHHH
PIIAFFFSFNAVSWSISTEAFFYLVFPVLRHRWESTWHWKSGIVALIAFGVLAVVNPYRI
HHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEE
SLANPQTPLTISAEGIGYISPFVRVIEFLLGMLTATAFDAIRKWPLPKGVAFWTVLEVSA
EECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IGLIVFIERLAGYTATSPWTVFTVECTDAPAFPLMILVFAFGNGLISKLVSVRPLVILGE
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCEEEECC
ASFALYLSHLLLFNVFDSYRGSLAFSDLTLCIGYWIAAIAISLLLWSFIEKPARTQIRRL
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GSKEKPVAAGTI
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]