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The map label for this gene is cobP [H]

Identifier: 186476955

GI number: 186476955

Start: 2478824

End: 2479372

Strand: Direct

Name: cobP [H]

Synonym: Bphy_2204

Alternate gene names: 186476955

Gene position: 2478824-2479372 (Clockwise)

Preceding gene: 186476952

Following gene: 186476956

Centisome position: 71.25

GC content: 67.4

Gene sequence:

>549_bases
ATGATTTCCCGCGACCTCACCTTCGTCCTCGGCGGCGCGCGCTCGGGCAAGAGCCTGCATGCCGAACAACTCGCAAGCAC
GAGCGCATGGCCCGTGACCTATGTTGCGACCGCACGCATCGGCGACGACGAATTCGCCGCACGCGTCGCGCGTCATCGCG
AGCGGCGGCCCGCGAATTGGGCGCTGCTCGAAGCGCCGCTCGATCTGCCGCAAGCCACCGCATCGATCGACCGTTCGGAG
CACTGCATTCTGATCGACTGCCTGACGCTGTGGCTCGCGAACCTGCTCTGCCCTGCCGACGGCTCGCCGCCGCTTGCCGA
CTACCCCGACCGCCTCGCCGCGCTCGAAACGACGCTCGCGCAAGCGCGCTCGAAGATCATCGTCGTCAGCAACGAGATCG
GTCTCGGCGTGGTGCCGCTCGGTGCAGCGACGCGACTCTACGTCGATGAACTGGGACGCCTGAACCAGCGCATCGCGGCC
ATCAGCACGCAGACCACGATGATGGTCGCGGGCCTGCCGCTGCAACTCAAACCGGCGAGCCGCGCATGA

Upstream 100 bases:

>100_bases
ACGGTGGCCACGAGCGCAAGCGGAAAAAAGGGAAGCCCGCATTATCCCATCGCGCCTGCGTCCCGCGCTGCCACGGCAGC
ACAGTCGGTACAATCACGCG

Downstream 100 bases:

>100_bases
TGCTCCTGTCCCTGCCCTTCGTCGCGACACTCGCCACGGCAGCCGTCGCCGTGGACAGATGGCTCGGCGAGCCCGAGCGC
GGGCATCCCCTCGTCGCTTT

Product: adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MISRDLTFVLGGARSGKSLHAEQLASTSAWPVTYVATARIGDDEFAARVARHRERRPANWALLEAPLDLPQATASIDRSE
HCILIDCLTLWLANLLCPADGSPPLADYPDRLAALETTLAQARSKIIVVSNEIGLGVVPLGAATRLYVDELGRLNQRIAA
ISTQTTMMVAGLPLQLKPASRA

Sequences:

>Translated_182_residues
MISRDLTFVLGGARSGKSLHAEQLASTSAWPVTYVATARIGDDEFAARVARHRERRPANWALLEAPLDLPQATASIDRSE
HCILIDCLTLWLANLLCPADGSPPLADYPDRLAALETTLAQARSKIIVVSNEIGLGVVPLGAATRLYVDELGRLNQRIAA
ISTQTTMMVAGLPLQLKPASRA
>Mature_182_residues
MISRDLTFVLGGARSGKSLHAEQLASTSAWPVTYVATARIGDDEFAARVARHRERRPANWALLEAPLDLPQATASIDRSE
HCILIDCLTLWLANLLCPADGSPPLADYPDRLAALETTLAQARSKIIVVSNEIGLGVVPLGAATRLYVDELGRLNQRIAA
ISTQTTMMVAGLPLQLKPASRA

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=34.2541436464088, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19564; Mature: 19564

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRDLTFVLGGARSGKSLHAEQLASTSAWPVTYVATARIGDDEFAARVARHRERRPANW
CCCCCEEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCE
ALLEAPLDLPQATASIDRSEHCILIDCLTLWLANLLCPADGSPPLADYPDRLAALETTLA
EEEECCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
QARSKIIVVSNEIGLGVVPLGAATRLYVDELGRLNQRIAAISTQTTMMVAGLPLQLKPAS
HHCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCC
RA
CC
>Mature Secondary Structure
MISRDLTFVLGGARSGKSLHAEQLASTSAWPVTYVATARIGDDEFAARVARHRERRPANW
CCCCCEEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCE
ALLEAPLDLPQATASIDRSEHCILIDCLTLWLANLLCPADGSPPLADYPDRLAALETTLA
EEEECCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
QARSKIIVVSNEIGLGVVPLGAATRLYVDELGRLNQRIAAISTQTTMMVAGLPLQLKPAS
HHCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCC
RA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]