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The map label for this gene is ompR [H]

Identifier: 186476911

GI number: 186476911

Start: 2422400

End: 2423125

Strand: Reverse

Name: ompR [H]

Synonym: Bphy_2160

Alternate gene names: 186476911

Gene position: 2423125-2422400 (Counterclockwise)

Preceding gene: 186476913

Following gene: 186476910

Centisome position: 69.65

GC content: 65.7

Gene sequence:

>726_bases
ATGGCTACTCAAATTCTTGTCGTCGACGACGACGTCGAACTGCGCGACCTGCTGCGCGATTATCTGGCCCGCCAGGGCAT
CGAGGTATCGGTGCTGCACGACGCCAGTTCCCTGGAACGCCGTATCGAGCGCGAACGGCCCGATCTGATCGTGCTCGACC
TGATGATGCCGGGCGTCGACGGCCTCACGGCGCTGCGCAAGCTGCGTGCGTCGGGCGACGACATCCCGGTCATCATGCTC
ACCGCGCGCGCCGACGACGTGGACCGCATCGTCGGGCTGGAACTGGGTGCCGACGATTACCTCGGCAAGCCGTTCAATCC
GCGCGAACTGCTGGCGCGGGTGCAGGCGGTGTTGCGCCGCCGCAAGACGGTGCCGTCGGCCGCTGCGCCTGAGCAGCGCG
AGCCGTTCTCGTTCGGCCGCTTCACGCTGGACTTCCAGTCGCGCACGCTACATCAGGAAGGCAAGCCGCTCACACTGTCG
GGCAGCGAATTCGCGCTTCTGAAGATTTTCGTCAACCACCCGATGCGCACGCTCACCCGCGAGCGCCTGCTCGAACTGCT
GCACGGGCCGGAGTACGACGGTACGGACCGCGGCATCGACGTGCAGGTGTGGCGCCTGCGGCGCATTCTCGAAACCGATC
CGTCCGTGCCGCGCTTCATTCAGACAGTGCGCGGACGCGGATACGTGTTCGTCCCGGATGGCGAGCAACATGCGTCGTCC
AATTGA

Upstream 100 bases:

>100_bases
GTTACGCGACATTACGTGCGCCTTTCGCGGTAACACCCGGTAACCCTTTCGGGGCCGGACGGGTCCGAAACGCTTCGGGG
CGCGCGTTACACTTCGAACC

Downstream 100 bases:

>100_bases
TTCATTGTTCGGGCGGCTCGCGCTGCTTGTCGTGTGCGTGTTGCTGGTGTCGCATTTCGCATGGTACTTGCTGGTCCGTT
TTGAACGGAACCAGTCGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MATQILVVDDDVELRDLLRDYLARQGIEVSVLHDASSLERRIERERPDLIVLDLMMPGVDGLTALRKLRASGDDIPVIML
TARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRKTVPSAAAPEQREPFSFGRFTLDFQSRTLHQEGKPLTLS
GSEFALLKIFVNHPMRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSVPRFIQTVRGRGYVFVPDGEQHASS
N

Sequences:

>Translated_241_residues
MATQILVVDDDVELRDLLRDYLARQGIEVSVLHDASSLERRIERERPDLIVLDLMMPGVDGLTALRKLRASGDDIPVIML
TARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRKTVPSAAAPEQREPFSFGRFTLDFQSRTLHQEGKPLTLS
GSEFALLKIFVNHPMRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSVPRFIQTVRGRGYVFVPDGEQHASS
N
>Mature_240_residues
ATQILVVDDDVELRDLLRDYLARQGIEVSVLHDASSLERRIERERPDLIVLDLMMPGVDGLTALRKLRASGDDIPVIMLT
ARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRRKTVPSAAAPEQREPFSFGRFTLDFQSRTLHQEGKPLTLSG
SEFALLKIFVNHPMRTLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSVPRFIQTVRGRGYVFVPDGEQHASSN

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=51.0729613733906, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.0862068965517, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=38.6266094420601, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=34.7457627118644, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=40.6779661016949, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=37.3390557939914, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.042735042735, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=36.480686695279, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=36.2068965517241, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=34.8214285714286, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=36.1233480176211, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=31.8777292576419, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=29.9559471365639, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=32.618025751073, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=34.1880341880342, Blast_Score=71, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=34.3137254901961, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27346; Mature: 27215

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQILVVDDDVELRDLLRDYLARQGIEVSVLHDASSLERRIERERPDLIVLDLMMPGVD
CCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCEEEEEECCCCCH
GLTALRKLRASGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRR
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKTVPSAAAPEQREPFSFGRFTLDFQSRTLHQEGKPLTLSGSEFALLKIFVNHPMRTLTR
HHCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEECCCCEEEEHHHHHCCHHHHHH
ERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSVPRFIQTVRGRGYVFVPDGEQHASS
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHCCCC
N
C
>Mature Secondary Structure 
ATQILVVDDDVELRDLLRDYLARQGIEVSVLHDASSLERRIERERPDLIVLDLMMPGVD
CCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCEEEEEECCCCCH
GLTALRKLRASGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRR
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKTVPSAAAPEQREPFSFGRFTLDFQSRTLHQEGKPLTLSGSEFALLKIFVNHPMRTLTR
HHCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEECCCCEEEEHHHHHCCHHHHHH
ERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSVPRFIQTVRGRGYVFVPDGEQHASS
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]