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The map label for this gene is proW [C]

Identifier: 186476907

GI number: 186476907

Start: 2416423

End: 2418177

Strand: Reverse

Name: proW [C]

Synonym: Bphy_2156

Alternate gene names: 186476907

Gene position: 2418177-2416423 (Counterclockwise)

Preceding gene: 186476910

Following gene: 186476906

Centisome position: 69.5

GC content: 63.99

Gene sequence:

>1755_bases
ATGGATCTGTTCAGCTTCACCCTGAACCGCACCGCCAACGCGTCCGCCTGGCGGGTGCTGCCCAATCGCTGGGACTTCAT
TGCGTTCCCGCTGATCATCTGTCTGATCGCGATGGCCGTCGTCGGCTTCCACGAAACGATGGCGCCCATCTCGACTTTGC
AGAACGCGCCGATCTCGCTCGATCCGGCCAATCTGCCCGAGTATGCGCTGCGCACCACGCTGCGCATGCTCGCTGCGATG
GTGGCGTCGCTGGTGTTCACGCTCGTCTACGGCACGCTGGCGGCCAAGAGCCGCCGCGCGGGCCAGGTGCTCGTGCCGAT
TCTCGACATCCTGCAATCGGTGCCCGTGCTCGGCTACATCTCGTTCACGGTGACGTTCTTCCTCGCGCTCTTTCCGTCTC
GCGTGCTGGGCGCCGAACTGGCCGCGATCTTCGCGATCTTCACCAGCCAGGCGTGGAACATGACCTTCAGCTTCTACCAG
TCGCTGCGCACGGTGCCGCGCGATCTGGACGAAGTGTCGAAGGGCTTCCATCTGACGTCGTGGCAGCGCTTCTGGAAGCT
CGAAGTGCCGTTCTCGATGCCCGGCCTCATCTGGAACATGATGATGTCGATGTCGGGCGGCTGGTTCTTCGTGGTGGCGT
CCGAAGCGATCACCGTCGGTAACCATACGATCACGCTGCCTGGCATGGGCTCGTATCTGGCGCAGGCCATCGCCGAAAAA
AACCTGCACGCAATCGGCTGGGTGATCCTGACAATGACGGTGGTGATTCTCGCGTACGACCAGTTCCTGTTCCGTCCGCT
CGTCGCGTGGACCGACAAGTTCCGCATGGAGAACACGAGTTCCGGCGACGCGCCCGAGTCGTGGCTGCTCGACCTGATCC
GCCGCACGCGCCTGATTCACCGGCTGCTCGTGCCGATCGGCTGGATGTTCGCGAAGGCGGCGCGTGTGCCTATCCGCTGG
CCGCGCGTCGGTCCGGTGCGCTTCGCGAAGCCGGTCGAGCACAAGCCGTCGAAGACGGGCGACATCGTCTGGTCCGTGAT
CGTCATGCTGGTGACGGCGTTCGTCGTGTACCGCGTGGTCGCGTATGTGCGTACGGGAGTCACGCTCGATGAAGTCGGCC
ATGTGTTCGTCCTCGGCCTGCTGACGCTGCTGCGCGTGACGTTGCTGATTGCGCTGGCTTCCGTGGTGTGGCTGCCCGTG
GGCGTACTGATCGGTCTGCGTCCGGCGCTCGCCGAGAAGGTCCAGCCGCTCGCGCAGTTTCTCGCCGCGTTCCCCGCAAA
CCTGCTGTTCCCGGCGTTCGTGCTCGTGATCGTGAGGTTCGATCTGAACCCGGACATCTGGCTTTCGCCGCTGATCGTGC
TCGGCACGCAGTGGTATATCCTGTTCAACGTGATTGCGGGCGCGAGCGCCTATCCGAACGACTACAAGGAAGCCGCGAAG
AACTTCCGCATCCGCGGCTGGCAATGGTGGCGTCAGGCGATGCTGCCGGGCGTGTTCCCGTACTACGTGACGGGAGCGAT
CACGGCCTCGGGCGGCGCGTGGAATGCGAGCATCGTCGCGGAGGCGGTGCAGTGGGGCGATACCAAGGTCGCTGCGCACG
GCCTCGGCGCGTATATCGCGCAGTACACGGCGGCGGGCGACTATCCGAAAATCATTCTGGGCATCGCGGTGATGTCCCTG
TTCGTGTCCCTCTTCAATCGCGTGTTGTGGCGCCCTCTGTACGCCTACGCCGAAAGCCGCCTGCGGCTCGATTGA

Upstream 100 bases:

>100_bases
GAACCCCGGACCGTCGCGCCGCCGCGACCCATGACGGCGCGGGCGTAGCCGTCATGGCTTGCTGCATGGCCGCGTGTCGC
CGCAAACAGAGGGGCGTCTG

Downstream 100 bases:

>100_bases
GATTCATTGAAGGCATAACGCGATGCAACATCCAAAGACCGTAACGGCCGCCACGCCAGTCCAGACGCCGCCGATGCCAC
CGCGCCTCGGCGACGAAATC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease; ABC Transporter Membrane Protein; ABC Transporter Nitrate Permease; ABC Transporter; ABC Anion Transporter; ABC-Type Anion Transport System Permease Component; Anion Transporter Permease Protein; Nitrate ABC Transporter Permease; ABC Transporter Inner Membrane Subunit; ABC Transporter Transmembrane Permease Protein; ABC-Type Anion Transport System; ABC-Type Nitrate Transport Permease; ABC Transport System Permease Protein; Transmembrane ABC Transporter Protein; Nitrate Transport System Permease Protein; Nitrate ABC Transporter Permease Protein; Anion ABC Transporter Permease; Taurine ABC Transporter Permease Protein; Sugar ABC Transporter; Sugar ABC Transporter 1 Permease Protein; Sulfonate Transport Permease Protein; Nitrate Transport System Permease

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MDLFSFTLNRTANASAWRVLPNRWDFIAFPLIICLIAMAVVGFHETMAPISTLQNAPISLDPANLPEYALRTTLRMLAAM
VASLVFTLVYGTLAAKSRRAGQVLVPILDILQSVPVLGYISFTVTFFLALFPSRVLGAELAAIFAIFTSQAWNMTFSFYQ
SLRTVPRDLDEVSKGFHLTSWQRFWKLEVPFSMPGLIWNMMMSMSGGWFFVVASEAITVGNHTITLPGMGSYLAQAIAEK
NLHAIGWVILTMTVVILAYDQFLFRPLVAWTDKFRMENTSSGDAPESWLLDLIRRTRLIHRLLVPIGWMFAKAARVPIRW
PRVGPVRFAKPVEHKPSKTGDIVWSVIVMLVTAFVVYRVVAYVRTGVTLDEVGHVFVLGLLTLLRVTLLIALASVVWLPV
GVLIGLRPALAEKVQPLAQFLAAFPANLLFPAFVLVIVRFDLNPDIWLSPLIVLGTQWYILFNVIAGASAYPNDYKEAAK
NFRIRGWQWWRQAMLPGVFPYYVTGAITASGGAWNASIVAEAVQWGDTKVAAHGLGAYIAQYTAAGDYPKIILGIAVMSL
FVSLFNRVLWRPLYAYAESRLRLD

Sequences:

>Translated_584_residues
MDLFSFTLNRTANASAWRVLPNRWDFIAFPLIICLIAMAVVGFHETMAPISTLQNAPISLDPANLPEYALRTTLRMLAAM
VASLVFTLVYGTLAAKSRRAGQVLVPILDILQSVPVLGYISFTVTFFLALFPSRVLGAELAAIFAIFTSQAWNMTFSFYQ
SLRTVPRDLDEVSKGFHLTSWQRFWKLEVPFSMPGLIWNMMMSMSGGWFFVVASEAITVGNHTITLPGMGSYLAQAIAEK
NLHAIGWVILTMTVVILAYDQFLFRPLVAWTDKFRMENTSSGDAPESWLLDLIRRTRLIHRLLVPIGWMFAKAARVPIRW
PRVGPVRFAKPVEHKPSKTGDIVWSVIVMLVTAFVVYRVVAYVRTGVTLDEVGHVFVLGLLTLLRVTLLIALASVVWLPV
GVLIGLRPALAEKVQPLAQFLAAFPANLLFPAFVLVIVRFDLNPDIWLSPLIVLGTQWYILFNVIAGASAYPNDYKEAAK
NFRIRGWQWWRQAMLPGVFPYYVTGAITASGGAWNASIVAEAVQWGDTKVAAHGLGAYIAQYTAAGDYPKIILGIAVMSL
FVSLFNRVLWRPLYAYAESRLRLD
>Mature_584_residues
MDLFSFTLNRTANASAWRVLPNRWDFIAFPLIICLIAMAVVGFHETMAPISTLQNAPISLDPANLPEYALRTTLRMLAAM
VASLVFTLVYGTLAAKSRRAGQVLVPILDILQSVPVLGYISFTVTFFLALFPSRVLGAELAAIFAIFTSQAWNMTFSFYQ
SLRTVPRDLDEVSKGFHLTSWQRFWKLEVPFSMPGLIWNMMMSMSGGWFFVVASEAITVGNHTITLPGMGSYLAQAIAEK
NLHAIGWVILTMTVVILAYDQFLFRPLVAWTDKFRMENTSSGDAPESWLLDLIRRTRLIHRLLVPIGWMFAKAARVPIRW
PRVGPVRFAKPVEHKPSKTGDIVWSVIVMLVTAFVVYRVVAYVRTGVTLDEVGHVFVLGLLTLLRVTLLIALASVVWLPV
GVLIGLRPALAEKVQPLAQFLAAFPANLLFPAFVLVIVRFDLNPDIWLSPLIVLGTQWYILFNVIAGASAYPNDYKEAAK
NFRIRGWQWWRQAMLPGVFPYYVTGAITASGGAWNASIVAEAVQWGDTKVAAHGLGAYIAQYTAAGDYPKIILGIAVMSL
FVSLFNRVLWRPLYAYAESRLRLD

Specific function: Involved In A Multicomponent Binding-Protein-Dependent Transport System For Glycine Betaine/L-Proline. [C]

COG id: COG4986

COG function: function code P; ABC-type anion transport system, duplicated permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 65171; Mature: 65171

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFSFTLNRTANASAWRVLPNRWDFIAFPLIICLIAMAVVGFHETMAPISTLQNAPISL
CCCHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPANLPEYALRTTLRMLAAMVASLVFTLVYGTLAAKSRRAGQVLVPILDILQSVPVLGYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHH
SFTVTFFLALFPSRVLGAELAAIFAIFTSQAWNMTFSFYQSLRTVPRDLDEVSKGFHLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
WQRFWKLEVPFSMPGLIWNMMMSMSGGWFFVVASEAITVGNHTITLPGMGSYLAQAIAEK
HHHHEEEECCCCCHHHHHHHHHHCCCCEEEEEECCEEEECCEEEECCCCHHHHHHHHHHC
NLHAIGWVILTMTVVILAYDQFLFRPLVAWTDKFRMENTSSGDAPESWLLDLIRRTRLIH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RLLVPIGWMFAKAARVPIRWPRVGPVRFAKPVEHKPSKTGDIVWSVIVMLVTAFVVYRVV
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AYVRTGVTLDEVGHVFVLGLLTLLRVTLLIALASVVWLPVGVLIGLRPALAEKVQPLAQF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAAFPANLLFPAFVLVIVRFDLNPDIWLSPLIVLGTQWYILFNVIAGASAYPNDYKEAAK
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NFRIRGWQWWRQAMLPGVFPYYVTGAITASGGAWNASIVAEAVQWGDTKVAAHGLGAYIA
CCCCCHHHHHHHHHCCCCCHHHHHHEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
QYTAAGDYPKIILGIAVMSLFVSLFNRVLWRPLYAYAESRLRLD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLFSFTLNRTANASAWRVLPNRWDFIAFPLIICLIAMAVVGFHETMAPISTLQNAPISL
CCCHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPANLPEYALRTTLRMLAAMVASLVFTLVYGTLAAKSRRAGQVLVPILDILQSVPVLGYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHH
SFTVTFFLALFPSRVLGAELAAIFAIFTSQAWNMTFSFYQSLRTVPRDLDEVSKGFHLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
WQRFWKLEVPFSMPGLIWNMMMSMSGGWFFVVASEAITVGNHTITLPGMGSYLAQAIAEK
HHHHEEEECCCCCHHHHHHHHHHCCCCEEEEEECCEEEECCEEEECCCCHHHHHHHHHHC
NLHAIGWVILTMTVVILAYDQFLFRPLVAWTDKFRMENTSSGDAPESWLLDLIRRTRLIH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RLLVPIGWMFAKAARVPIRWPRVGPVRFAKPVEHKPSKTGDIVWSVIVMLVTAFVVYRVV
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AYVRTGVTLDEVGHVFVLGLLTLLRVTLLIALASVVWLPVGVLIGLRPALAEKVQPLAQF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAAFPANLLFPAFVLVIVRFDLNPDIWLSPLIVLGTQWYILFNVIAGASAYPNDYKEAAK
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NFRIRGWQWWRQAMLPGVFPYYVTGAITASGGAWNASIVAEAVQWGDTKVAAHGLGAYIA
CCCCCHHHHHHHHHCCCCCHHHHHHEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
QYTAAGDYPKIILGIAVMSLFVSLFNRVLWRPLYAYAESRLRLD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA