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The map label for this gene is qorA [H]

Identifier: 186476767

GI number: 186476767

Start: 2262112

End: 2263128

Strand: Reverse

Name: qorA [H]

Synonym: Bphy_2012

Alternate gene names: 186476767

Gene position: 2263128-2262112 (Counterclockwise)

Preceding gene: 186476768

Following gene: 186476766

Centisome position: 65.05

GC content: 62.24

Gene sequence:

>1017_bases
ATGAACGCAATCGAAATCACCGAATTCGGTGCGCCGGAAGTCTTGAAACTCGCCGAACGGCCGATGCCGGAGCCGAAGGC
AGGCGAAGTGCTGATCAAGGTGGCCGCATCGGGCGTGAATCGCCCGGACGTGTTCCAGCGCAAGGGCGGCTATGCACCAC
CGCCGGGCGCGTCGGACCTGCCGGGGCTCGAAGTGGCGGGAGAAATCGTCGGCGGAAACATCGACGAAAAGCGCAATCCG
TTCGGTCTGAAGATCGGCGACCGCGTGTGTGCGCTGATGGCGGGCGGCGGCTATGCCGAGTACGCAACGGTGCCGCTGCT
GCAATGTCTGCCTGTGCCGAAAGGCTTTTCCGATATCGAAGCGGCGGCATTGCCCGAAACGTTCTTCACGGTCTGGAGCA
ATGTTTTTGACCGTGCAATGCTCGGCAAAGGCGAGGGCGGCGAGAACGAGACGTTCCTCGTGCAGGGAGGTTCGAGTGGC
ATCGGCGTGACGGCGATCCAGATTGCGCATGCACTGGGTTTTCGCGTGTTCGCCACGGCCGGCACGGACGAAAAGTGCCG
GGCGTGCGAAGCGATCGGCGCCGAGCGCGCCATCAACTATAAGACGGAAGACTTCGTCGAGGTGATCAAGTCGCTCACGA
ACGATCGCGGCGTCGACGTGATTCTCGATATGGTCGCCGGCAGTTATGTGCCACGTGAACTGAAGGCGCTGGCCGATGGA
GGTCGTCTGGTAGTGATCGCGCTGCTGGGTGGCGCGAAGTCGGAAGTGAACCTGAACGAGATTCTGCGGCGCCGCCTCAC
GGTCACGGGTTCGACGCTGCGCCCGCGGCCTGTCGAGTTCAAGGCGAAGATCGCTGCGCAACTGAAAGAGCATGTTTGGC
CGCATCTCGAAGACGGCACGATCAAGCCGGTGATCTACAAGGTGTTCCCCGCGGCTGACGCCGCGAAGGCGCACGAACTG
ATGGAAAGCAGCACGCACGTCGGCAAGATTGTGCTGAATTGGGGCGCGGGCGCTTGA

Upstream 100 bases:

>100_bases
CAAAAGCGCGCCGGCCGTTTTTCATGTAGGGTGGATTGCAGTGCGAACCGGTTTTTGTCTGACCGGTTTGCAGCGCTATC
CAGACCTGGGAGAGACGACG

Downstream 100 bases:

>100_bases
CAGCGCTCGTTTAATTGAGTTTGACCGGGTCTGTCAGCACACAGTAAAATCGCACGTTTTGCGCGTTCTGCATGGTTTTT
GCATGCGGACCGGGTACCGG

Product: PIG3 family NAD(P)H quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNAIEITEFGAPEVLKLAERPMPEPKAGEVLIKVAASGVNRPDVFQRKGGYAPPPGASDLPGLEVAGEIVGGNIDEKRNP
FGLKIGDRVCALMAGGGYAEYATVPLLQCLPVPKGFSDIEAAALPETFFTVWSNVFDRAMLGKGEGGENETFLVQGGSSG
IGVTAIQIAHALGFRVFATAGTDEKCRACEAIGAERAINYKTEDFVEVIKSLTNDRGVDVILDMVAGSYVPRELKALADG
GRLVVIALLGGAKSEVNLNEILRRRLTVTGSTLRPRPVEFKAKIAAQLKEHVWPHLEDGTIKPVIYKVFPAADAAKAHEL
MESSTHVGKIVLNWGAGA

Sequences:

>Translated_338_residues
MNAIEITEFGAPEVLKLAERPMPEPKAGEVLIKVAASGVNRPDVFQRKGGYAPPPGASDLPGLEVAGEIVGGNIDEKRNP
FGLKIGDRVCALMAGGGYAEYATVPLLQCLPVPKGFSDIEAAALPETFFTVWSNVFDRAMLGKGEGGENETFLVQGGSSG
IGVTAIQIAHALGFRVFATAGTDEKCRACEAIGAERAINYKTEDFVEVIKSLTNDRGVDVILDMVAGSYVPRELKALADG
GRLVVIALLGGAKSEVNLNEILRRRLTVTGSTLRPRPVEFKAKIAAQLKEHVWPHLEDGTIKPVIYKVFPAADAAKAHEL
MESSTHVGKIVLNWGAGA
>Mature_338_residues
MNAIEITEFGAPEVLKLAERPMPEPKAGEVLIKVAASGVNRPDVFQRKGGYAPPPGASDLPGLEVAGEIVGGNIDEKRNP
FGLKIGDRVCALMAGGGYAEYATVPLLQCLPVPKGFSDIEAAALPETFFTVWSNVFDRAMLGKGEGGENETFLVQGGSSG
IGVTAIQIAHALGFRVFATAGTDEKCRACEAIGAERAINYKTEDFVEVIKSLTNDRGVDVILDMVAGSYVPRELKALADG
GRLVVIALLGGAKSEVNLNEILRRRLTVTGSTLRPRPVEFKAKIAAQLKEHVWPHLEDGTIKPVIYKVFPAADAAKAHEL
MESSTHVGKIVLNWGAGA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=338, Percent_Identity=36.3905325443787, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI22538444, Length=338, Percent_Identity=36.3905325443787, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=33.8278931750742, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=33.8278931750742, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI194239676, Length=337, Percent_Identity=30.8605341246291, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI18379349, Length=355, Percent_Identity=28.169014084507, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI24308257, Length=354, Percent_Identity=26.5536723163842, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=32.0652173913043, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI28557745, Length=285, Percent_Identity=29.4736842105263, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=25.9375, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI47519420, Length=363, Percent_Identity=26.4462809917355, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=339, Percent_Identity=31.5634218289086, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787863, Length=354, Percent_Identity=25.9887005649718, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=346, Percent_Identity=28.6127167630058, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=327, Percent_Identity=25.9938837920489, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=27.3255813953488, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=350, Percent_Identity=24.2857142857143, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24581345, Length=251, Percent_Identity=24.3027888446215, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920632, Length=280, Percent_Identity=23.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330659, Length=280, Percent_Identity=23.5714285714286, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35900; Mature: 35900

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIEITEFGAPEVLKLAERPMPEPKAGEVLIKVAASGVNRPDVFQRKGGYAPPPGASDL
CCCEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGNIDEKRNPFGLKIGDRVCALMAGGGYAEYATVPLLQCLPVPKGFSDIE
CCHHHHHHHHCCCCCCCCCCCCEEHHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRAMLGKGEGGENETFLVQGGSSGIGVTAIQIAHALGFRVFATA
HHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEC
GTDEKCRACEAIGAERAINYKTEDFVEVIKSLTNDRGVDVILDMVAGSYVPRELKALADG
CCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCC
GRLVVIALLGGAKSEVNLNEILRRRLTVTGSTLRPRPVEFKAKIAAQLKEHVWPHLEDGT
CCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IKPVIYKVFPAADAAKAHELMESSTHVGKIVLNWGAGA
CCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNAIEITEFGAPEVLKLAERPMPEPKAGEVLIKVAASGVNRPDVFQRKGGYAPPPGASDL
CCCEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGNIDEKRNPFGLKIGDRVCALMAGGGYAEYATVPLLQCLPVPKGFSDIE
CCHHHHHHHHCCCCCCCCCCCCEEHHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRAMLGKGEGGENETFLVQGGSSGIGVTAIQIAHALGFRVFATA
HHHCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEC
GTDEKCRACEAIGAERAINYKTEDFVEVIKSLTNDRGVDVILDMVAGSYVPRELKALADG
CCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCC
GRLVVIALLGGAKSEVNLNEILRRRLTVTGSTLRPRPVEFKAKIAAQLKEHVWPHLEDGT
CCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IKPVIYKVFPAADAAKAHELMESSTHVGKIVLNWGAGA
CCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]