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The map label for this gene is nuoA

Identifier: 186476764

GI number: 186476764

Start: 2259968

End: 2260339

Strand: Reverse

Name: nuoA

Synonym: Bphy_2009

Alternate gene names: 186476764

Gene position: 2260339-2259968 (Counterclockwise)

Preceding gene: 186476765

Following gene: 186476763

Centisome position: 64.97

GC content: 53.76

Gene sequence:

>372_bases
TTGAGGATAGCTTTGAACCTCGCAGCCTATTTCCCCGTATTGATGTTCCTCCTCGTGGGCACCGGTTTAGGCGTAGCACT
GGTCAGTATCGGCAAGATCCTCGGTCCGAATCGACCGGACACCGAAAAGAACGCACCGTATGAGTGCGGCTTCGAAGCTT
TCGAAGATGCGCGCATGAAGTTTGACGTGCGCTACTACCTGGTCGCCATTCTCTTCATCATCTTCGACCTTGAAACGGCA
TTCCTGTTCCCGTGGGGCGTGGCTCTGCGCGATATCGGCTGGCCCGGCTTCATCTCGATGATGATTTTTCTGCTCGAATT
CCTGTTGGGCTTCGCCTATATCTGGAAGAAAGGTGGCCTTGACTGGGAATGA

Upstream 100 bases:

>100_bases
TGTTTGCTGTGGGCTTTCAACCTCAAGCATCCCGAAGTGTTTCGCGTCAGGGGTTGTTCAAGGTAGTTCGCGTCTCCTGA
CGTTACTCAGAACCAACCGA

Downstream 100 bases:

>100_bases
CGGGTTAATCGCCGGTGTGTATGGGTGGCGACGGCTCGCCGCCCGTCTGGAGTGGAAAACAAATGAGTATCGAAGGGGTC
TTGAAGGAAGGGTTTGTCAC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MRIALNLAAYFPVLMFLLVGTGLGVALVSIGKILGPNRPDTEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETA
FLFPWGVALRDIGWPGFISMMIFLLEFLLGFAYIWKKGGLDWE

Sequences:

>Translated_123_residues
MRIALNLAAYFPVLMFLLVGTGLGVALVSIGKILGPNRPDTEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETA
FLFPWGVALRDIGWPGFISMMIFLLEFLLGFAYIWKKGGLDWE
>Mature_123_residues
MRIALNLAAYFPVLMFLLVGTGLGVALVSIGKILGPNRPDTEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETA
FLFPWGVALRDIGWPGFISMMIFLLEFLLGFAYIWKKGGLDWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=116, Percent_Identity=36.2068965517241, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_BURP8 (B2JDM8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858234.1
- GeneID:   6243498
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2009
- HOGENOM:   HBG605540
- OMA:   IGFAYEW
- ProtClustDB:   PRK06602
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13999; Mature: 13999

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1eea8f64)-; HASH(0x1e6b2828)-; HASH(0x1f3ca988)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALNLAAYFPVLMFLLVGTGLGVALVSIGKILGPNRPDTEKNAPYECGFEAFEDARMK
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
FDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFISMMIFLLEFLLGFAYIWKKGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DWE
CCH
>Mature Secondary Structure
MRIALNLAAYFPVLMFLLVGTGLGVALVSIGKILGPNRPDTEKNAPYECGFEAFEDARMK
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
FDVRYYLVAILFIIFDLETAFLFPWGVALRDIGWPGFISMMIFLLEFLLGFAYIWKKGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DWE
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA