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The map label for this gene is nuoG [H]

Identifier: 186476758

GI number: 186476758

Start: 2253132

End: 2255465

Strand: Reverse

Name: nuoG [H]

Synonym: Bphy_2003

Alternate gene names: 186476758

Gene position: 2255465-2253132 (Counterclockwise)

Preceding gene: 186476759

Following gene: 186476757

Centisome position: 64.83

GC content: 64.35

Gene sequence:

>2334_bases
ATGGTTGAACTTGAAATAGACGGCAAGAAAGTAGAGGTGGCCGAAGGCAGCATGATCATTCAGGCTGCGCATAAGGTCGA
TACCTATATCCCTCACTTCTGCTATCACAAGAAGCTGTCGATTGCGGCCAACTGCCGGATGTGTCTCGTCGATGTCGAGA
AGATGCCGAAGGCCGTGCCTGCGTGCGCGACGCCGGTGTCGGCGGGCATGATCGTGCGCACCCAGTCGGAAAAGGCGGTG
AAGGGCCAGCAGTCGGTGATGGAATTCCTGCTGATCAATCACCCGCTCGATTGCCCGATCTGCGACCAGGGCGGCGAATG
CCAACTGCAGGATCTGGCTGTTGGTTACGGCAAGTCGTCGTCGCGTTACAGTGAAGAGAAGCGTGTGGTGTTCCACAAGA
ACGTGGGCCCGTTGATCTCGATGGAAGAGATGTCGCGCTGCATTCACTGCACGCGCTGCGTGCGCTTCGGCGAAGAAATC
GCTGGCGTGATGGAACTCGGCATGCTCGGCCGCGGCGAACACTCGGAAATCACGTCGTTCGTCGGGAAGACGGTGGACTC
CGAACTGTCGGGCAATATGATCGACCTTTGCCCGGTCGGTGCGCTGACCAGCAAGCCGTTCCGTTACAGCGCCCGCACGT
GGGAGCTGTCGCGCCGCAAGTCGGTGAGCCCGCACGATTCCGTCGGCGCGAACCTGGTGGTGCAGGTGAAGAACAATCGC
GTGATGCGCGTTCTGCCGTTCGAAAACGAATCCATCAACGAATGCTGGATTTCGGACAAGGACCGCTTCTCGTACGAAGG
CCTCAACAGCCCGGAACGTTTGACGCGCCCGATGCTGAAGCAGGGCGGCCAGTGGATCGAGACGGATTGGCAGACGGCGC
TTGAATACGTCGTCAAGGGCCTGAAGGGCATCAAGGACGACCACGGCGCGAACGCAATCGCGGCGCTCGGCAGCGCGCAT
AGCACGGTCGAGGAACTGTTCCTGCTCAAGCAGATCGCTCAGGCTGTCGGCACGCCGAACGTCGACTTCCGTCTGCGTCA
GACCGATTTCTCGGCGGGTGCAAACGGTACGCCGTGGCTCGGCACGTCGATCGCCAATCTGTCGATGCTCGACAGTGCGC
TGGTGATCGGTTCGTCGCTGCGCCGCGACCATCCACTGTTTGCCGCGCGTCTGCGTCAGGCAGCGAAGGGCGGCGCGACG
ATCACACTGCTGCAGGCGACGCGCGACGACGCGCTGATCCCGCAAGCGGCGCGCATCGCCGCGGCGCCGTCGGCCTGGCT
CGACGAACTGGCTGGCATCGCGGCTGCCGTGTCGGAAGCGAAGGGCGTCGCATTGCCAGAAGCATTCGCAGGCGCAACGG
CCTCCGATGCCGCGAAGCAGACGGCGGCTGCGCTCGGGGCAGGCGAAACGCGTGTCGTGCTGCTGGGCAACGGCGCTGTC
CAGCATCCGGAATTCGGGCGCATTCACGCAGCGGCTCAGTGGATCGCACAAACGACGGGTGCGACGCTCGGCTTCCTGAC
GGAAGCGGCGAATACGGTCGGCGCGCATCTCGTCAACGCATTGCCGGGCGAGGGTGGTCTGAACGCTCGCGAAGTGTTCG
AACAGCCGCGCAAGGGTTATGTGCTGCTGAACCTCGAACCTGAATTCGATACGGCTAACCCGGCGCAGGCGTTGGCCGCG
CTGAACCAGGCGGAAATGGTCGTCGTGCTGTCGCCGTTCCAGACGGGCGCCGAGTATGCCGACGTCCTGCTGCCCATCGC
GCCGTACACTGAAACGGCCGGCACGTTCGTCAACGCGGAAGGCACGGTGCAGATGTTCAACGGCGTCGTGCGTCCGCTTG
GCGATACGCGCCCGGCGTGGAAGGTGCTGCGCGTGCTGGGCAACCTGCTCGGCGCGTCGGGCTTCGACTTCGATACGGCG
GAAGAGGTGCGCGCCGCGGCGCTGGGCGACAGCGACCTCACGCCGCGTCTGTCGAACAGCACGTCGGTCGCCGTTGCGCG
CAGCAGCGCCGCGAAGGCAGCGCAAGGTACGTTCGAGCGCATCGCCGATGTGCCGATCTACCACGCCGACCAGCTCGTAC
GCCGCGCCGAATCGCTGCACCTGACGGCAGCGGCGCGGGCTGCCCATTCGGTCGGTCTGCCGGCCGCATTGTTCGACCGG
CTGGGTTTGAAGGAGGGCGACGCGGTGCGCGTTCGTCAGGGCGATCGCTCGGTGCAGATTCCGGCCGTGCGTGATGCGAA
TCTTGCGGAGACGGTCGTCCGCGTGTCGGCGGCTACGCCTGCCGGTGCAGCGCTGGGCAGCCTGTTCGGTGAACTGGTGG
TGGAGAAGGCGTAA

Upstream 100 bases:

>100_bases
CATAAAGCTGAGGCAGACGCGGGCGCTGCTGCGTCGCGATGAGCGAAGCAGCGAGCGGGCGAACGATTGAGCGGTAACAG
GTTAAGGAAGATTGACCATC

Downstream 100 bases:

>100_bases
ATGACCTTGTTCGAATCGATCAACGCGGGCGGCACCCAGATTCTCGGCGTCGCATGGCCCACCGTGTGGGCCCTCGTGCG
CATTCTCGTAGTGGCCGTCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MVELEIDGKKVEVAEGSMIIQAAHKVDTYIPHFCYHKKLSIAANCRMCLVDVEKMPKAVPACATPVSAGMIVRTQSEKAV
KGQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSSSRYSEEKRVVFHKNVGPLISMEEMSRCIHCTRCVRFGEEI
AGVMELGMLGRGEHSEITSFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENESINECWISDKDRFSYEGLNSPERLTRPMLKQGGQWIETDWQTALEYVVKGLKGIKDDHGANAIAALGSAH
STVEELFLLKQIAQAVGTPNVDFRLRQTDFSAGANGTPWLGTSIANLSMLDSALVIGSSLRRDHPLFAARLRQAAKGGAT
ITLLQATRDDALIPQAARIAAAPSAWLDELAGIAAAVSEAKGVALPEAFAGATASDAAKQTAAALGAGETRVVLLGNGAV
QHPEFGRIHAAAQWIAQTTGATLGFLTEAANTVGAHLVNALPGEGGLNAREVFEQPRKGYVLLNLEPEFDTANPAQALAA
LNQAEMVVVLSPFQTGAEYADVLLPIAPYTETAGTFVNAEGTVQMFNGVVRPLGDTRPAWKVLRVLGNLLGASGFDFDTA
EEVRAAALGDSDLTPRLSNSTSVAVARSSAAKAAQGTFERIADVPIYHADQLVRRAESLHLTAAARAAHSVGLPAALFDR
LGLKEGDAVRVRQGDRSVQIPAVRDANLAETVVRVSAATPAGAALGSLFGELVVEKA

Sequences:

>Translated_777_residues
MVELEIDGKKVEVAEGSMIIQAAHKVDTYIPHFCYHKKLSIAANCRMCLVDVEKMPKAVPACATPVSAGMIVRTQSEKAV
KGQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSSSRYSEEKRVVFHKNVGPLISMEEMSRCIHCTRCVRFGEEI
AGVMELGMLGRGEHSEITSFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENESINECWISDKDRFSYEGLNSPERLTRPMLKQGGQWIETDWQTALEYVVKGLKGIKDDHGANAIAALGSAH
STVEELFLLKQIAQAVGTPNVDFRLRQTDFSAGANGTPWLGTSIANLSMLDSALVIGSSLRRDHPLFAARLRQAAKGGAT
ITLLQATRDDALIPQAARIAAAPSAWLDELAGIAAAVSEAKGVALPEAFAGATASDAAKQTAAALGAGETRVVLLGNGAV
QHPEFGRIHAAAQWIAQTTGATLGFLTEAANTVGAHLVNALPGEGGLNAREVFEQPRKGYVLLNLEPEFDTANPAQALAA
LNQAEMVVVLSPFQTGAEYADVLLPIAPYTETAGTFVNAEGTVQMFNGVVRPLGDTRPAWKVLRVLGNLLGASGFDFDTA
EEVRAAALGDSDLTPRLSNSTSVAVARSSAAKAAQGTFERIADVPIYHADQLVRRAESLHLTAAARAAHSVGLPAALFDR
LGLKEGDAVRVRQGDRSVQIPAVRDANLAETVVRVSAATPAGAALGSLFGELVVEKA
>Mature_777_residues
MVELEIDGKKVEVAEGSMIIQAAHKVDTYIPHFCYHKKLSIAANCRMCLVDVEKMPKAVPACATPVSAGMIVRTQSEKAV
KGQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSSSRYSEEKRVVFHKNVGPLISMEEMSRCIHCTRCVRFGEEI
AGVMELGMLGRGEHSEITSFVGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
VMRVLPFENESINECWISDKDRFSYEGLNSPERLTRPMLKQGGQWIETDWQTALEYVVKGLKGIKDDHGANAIAALGSAH
STVEELFLLKQIAQAVGTPNVDFRLRQTDFSAGANGTPWLGTSIANLSMLDSALVIGSSLRRDHPLFAARLRQAAKGGAT
ITLLQATRDDALIPQAARIAAAPSAWLDELAGIAAAVSEAKGVALPEAFAGATASDAAKQTAAALGAGETRVVLLGNGAV
QHPEFGRIHAAAQWIAQTTGATLGFLTEAANTVGAHLVNALPGEGGLNAREVFEQPRKGYVLLNLEPEFDTANPAQALAA
LNQAEMVVVLSPFQTGAEYADVLLPIAPYTETAGTFVNAEGTVQMFNGVVRPLGDTRPAWKVLRVLGNLLGASGFDFDTA
EEVRAAALGDSDLTPRLSNSTSVAVARSSAAKAAQGTFERIADVPIYHADQLVRRAESLHLTAAARAAHSVGLPAALFDR
LGLKEGDAVRVRQGDRSVQIPAVRDANLAETVVRVSAATPAGAALGSLFGELVVEKA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=662, Percent_Identity=37.4622356495468, Blast_Score=397, Evalue=1e-110,
Organism=Escherichia coli, GI145693161, Length=697, Percent_Identity=27.403156384505, Blast_Score=213, Evalue=5e-56,
Organism=Escherichia coli, GI3868721, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=653, Percent_Identity=36.4471669218989, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI32566231, Length=616, Percent_Identity=36.8506493506493, Blast_Score=334, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=51.1904761904762, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24640559, Length=401, Percent_Identity=44.3890274314214, Blast_Score=342, Evalue=6e-94,
Organism=Drosophila melanogaster, GI24640557, Length=401, Percent_Identity=44.3890274314214, Blast_Score=342, Evalue=6e-94,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 82769; Mature: 82769

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELEIDGKKVEVAEGSMIIQAAHKVDTYIPHFCYHKKLSIAANCRMCLVDVEKMPKAVP
CEEEEECCCEEEEECCCEEEHHHHHHHHHCCHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVSAGMIVRTQSEKAVKGQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSS
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCC
SRYSEEKRVVFHKNVGPLISMEEMSRCIHCTRCVRFGEEIAGVMELGMLGRGEHSEITSF
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCEECHHHCCCCCCCCCCCEEEEEEECCC
VMRVLPFENESINECWISDKDRFSYEGLNSPERLTRPMLKQGGQWIETDWQTALEYVVKG
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
LKGIKDDHGANAIAALGSAHSTVEELFLLKQIAQAVGTPNVDFRLRQTDFSAGANGTPWL
HHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
GTSIANLSMLDSALVIGSSLRRDHPLFAARLRQAAKGGATITLLQATRDDALIPQAARIA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
AAPSAWLDELAGIAAAVSEAKGVALPEAFAGATASDAAKQTAAALGAGETRVVLLGNGAV
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
QHPEFGRIHAAAQWIAQTTGATLGFLTEAANTVGAHLVNALPGEGGLNAREVFEQPRKGY
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
VLLNLEPEFDTANPAQALAALNQAEMVVVLSPFQTGAEYADVLLPIAPYTETAGTFVNAE
EEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHEECCCCCCCCCCEECCC
GTVQMFNGVVRPLGDTRPAWKVLRVLGNLLGASGFDFDTAEEVRAAALGDSDLTPRLSNS
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
TSVAVARSSAAKAAQGTFERIADVPIYHADQLVRRAESLHLTAAARAAHSVGLPAALFDR
CEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LGLKEGDAVRVRQGDRSVQIPAVRDANLAETVVRVSAATPAGAALGSLFGELVVEKA
CCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVELEIDGKKVEVAEGSMIIQAAHKVDTYIPHFCYHKKLSIAANCRMCLVDVEKMPKAVP
CEEEEECCCEEEEECCCEEEHHHHHHHHHCCHHHHHCCCEECCCCEEEEEEHHHCCCCCC
ACATPVSAGMIVRTQSEKAVKGQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSS
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCC
SRYSEEKRVVFHKNVGPLISMEEMSRCIHCTRCVRFGEEIAGVMELGMLGRGEHSEITSF
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VGKTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSVGANLVVQVKNNR
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCEECHHHCCCCCCCCCCCEEEEEEECCC
VMRVLPFENESINECWISDKDRFSYEGLNSPERLTRPMLKQGGQWIETDWQTALEYVVKG
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
LKGIKDDHGANAIAALGSAHSTVEELFLLKQIAQAVGTPNVDFRLRQTDFSAGANGTPWL
HHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
GTSIANLSMLDSALVIGSSLRRDHPLFAARLRQAAKGGATITLLQATRDDALIPQAARIA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
AAPSAWLDELAGIAAAVSEAKGVALPEAFAGATASDAAKQTAAALGAGETRVVLLGNGAV
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
QHPEFGRIHAAAQWIAQTTGATLGFLTEAANTVGAHLVNALPGEGGLNAREVFEQPRKGY
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCE
VLLNLEPEFDTANPAQALAALNQAEMVVVLSPFQTGAEYADVLLPIAPYTETAGTFVNAE
EEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHEECCCCCCCCCCEECCC
GTVQMFNGVVRPLGDTRPAWKVLRVLGNLLGASGFDFDTAEEVRAAALGDSDLTPRLSNS
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
TSVAVARSSAAKAAQGTFERIADVPIYHADQLVRRAESLHLTAAARAAHSVGLPAALFDR
CEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LGLKEGDAVRVRQGDRSVQIPAVRDANLAETVVRVSAATPAGAALGSLFGELVVEKA
CCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA