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The map label for this gene is acdA [H]

Identifier: 186476747

GI number: 186476747

Start: 2242439

End: 2243635

Strand: Reverse

Name: acdA [H]

Synonym: Bphy_1992

Alternate gene names: 186476747

Gene position: 2243635-2242439 (Counterclockwise)

Preceding gene: 186476748

Following gene: 186476746

Centisome position: 64.49

GC content: 61.49

Gene sequence:

>1197_bases
ATGGATCTGAATTATTCCCCCGCCGACGACGCATTCCGCGCCGACATTCGCGCATGGCTCGAGGCTAATCTGCCTGACGC
GCTCCGCGACAAAGTCCTCAATCACAAACGTCTGAACCGCGACGATTACGCGAGCTGGCATGCGCTGCTCGGCAAGCGTG
GCTGGTCGGCCCCTGCATGGCCGGCCGAATACGGCGGACCGAACTGGAACGTGACGCAGCGTCATATTTGGGACGAGGAG
TGTGCCCGCCTCGGCGCGCCAACCGTGTTGCCGTTCGGTGTGTCGATGGTCGCGCCCGTGCTGATGAAATACGGCAGCGA
AGCGCAGAAGCGCCGCTATCTGCCGCGCATTCTCGACGGCAGCGACTGGTGGTGCCAGGGCTATTCGGAGCCCGGCTCGG
GTTCGGATCTCGCATCGTTGCGCACGCGTGCTCAACGTGTAGGCGATCACTATGTCGTGAATGGGCAGAAGACCTGGACG
ACGCTCGGCCAGCACGCCGACATGATGTTTTGTCTCGTGCGCACCGACAGCGGCGCGAAAAAGCAGGAAGGCATTTCGTT
CCTGCTGATCGACATGAAAACGCCGGGTATCACGGTGCGGCCCATCGTCACGCTCGACGAGGATCACGAAGTCAACGAAG
TGTTCTTCGAAGACGTGAAGGTCCCTGTCGAGAACCTGGTCGGCGATGAGAACCGCGGCTGGACTTACGCGAAATATCTG
CTTGGGCACGAGCGGACGGGTATCGCTCGCGTCGGCCAGTCGAAGCGCGAGCTGGCGTTTCTGAAGCAACTCGCGCTGAA
TCGGAAGAAGAACGGCAAGCCATTGCTGCACGATCCGCTCTTCGGCGCGAAGGTCGCGAGTCTCGAAATCGAACTGATGG
CGCTTGAAATAACGGTGCAGCGCGTCGTCGCGAATGAGGCGGGCGGACGCGGGCCGGGACCGGAGGCGTCGATGCTGAAG
ATCAAGGGTACGGAAGTGCAGCAAGGCCTGACTGAACTGATGTACGAAGCGGTCGGCCCGCTCGCGGCGCCGTTCGATGT
GCCGTTCCTGGAAGGCGAACGGGCGCACAGCATCGCGGGCGACGACGATGCCGCGCCGCTCGCCGCGTACTACTTCAACT
ACCGCAAGACGTCGATCTACGGCGGCTCGAACGAAATTCAAAAGAACATCATCGCGCAGATGATTCTCGGACTGTGA

Upstream 100 bases:

>100_bases
ATGCCGCTGCCTGTGCCCGCCGCACTGAAAGAGCCGCTGCAATAAGCGAACGCTTGCAGTGCTCCTGGCGGCGCAAGGCC
GCGGCCAGGAGACTCTGCGC

Downstream 100 bases:

>100_bases
GGCGCGGCGCATGAACTTCAATTTCACCGATGAACAGCAACAATTCGCCGACGCGCTGCGCCGTTATCTAGACAGGCACT
ACGCATTCGAAGCGCGCCAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDLNYSPADDAFRADIRAWLEANLPDALRDKVLNHKRLNRDDYASWHALLGKRGWSAPAWPAEYGGPNWNVTQRHIWDEE
CARLGAPTVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAQRVGDHYVVNGQKTWT
TLGQHADMMFCLVRTDSGAKKQEGISFLLIDMKTPGITVRPIVTLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGQSKRELAFLKQLALNRKKNGKPLLHDPLFGAKVASLEIELMALEITVQRVVANEAGGRGPGPEASMLK
IKGTEVQQGLTELMYEAVGPLAAPFDVPFLEGERAHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Sequences:

>Translated_398_residues
MDLNYSPADDAFRADIRAWLEANLPDALRDKVLNHKRLNRDDYASWHALLGKRGWSAPAWPAEYGGPNWNVTQRHIWDEE
CARLGAPTVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAQRVGDHYVVNGQKTWT
TLGQHADMMFCLVRTDSGAKKQEGISFLLIDMKTPGITVRPIVTLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGQSKRELAFLKQLALNRKKNGKPLLHDPLFGAKVASLEIELMALEITVQRVVANEAGGRGPGPEASMLK
IKGTEVQQGLTELMYEAVGPLAAPFDVPFLEGERAHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
>Mature_398_residues
MDLNYSPADDAFRADIRAWLEANLPDALRDKVLNHKRLNRDDYASWHALLGKRGWSAPAWPAEYGGPNWNVTQRHIWDEE
CARLGAPTVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDGSDWWCQGYSEPGSGSDLASLRTRAQRVGDHYVVNGQKTWT
TLGQHADMMFCLVRTDSGAKKQEGISFLLIDMKTPGITVRPIVTLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
LGHERTGIARVGQSKRELAFLKQLALNRKKNGKPLLHDPLFGAKVASLEIELMALEITVQRVVANEAGGRGPGPEASMLK
IKGTEVQQGLTELMYEAVGPLAAPFDVPFLEGERAHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=401, Percent_Identity=25.6857855361596, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4557233, Length=357, Percent_Identity=27.4509803921569, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226958414, Length=262, Percent_Identity=29.7709923664122, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI226958412, Length=262, Percent_Identity=29.7709923664122, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI48976061, Length=351, Percent_Identity=27.3504273504274, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI211971008, Length=351, Percent_Identity=27.3504273504274, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4501859, Length=340, Percent_Identity=27.6470588235294, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4557231, Length=301, Percent_Identity=27.2425249169435, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI187960098, Length=301, Percent_Identity=27.2425249169435, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI21361497, Length=307, Percent_Identity=29.6416938110749, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7656849, Length=210, Percent_Identity=29.0476190476191, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI76496475, Length=320, Percent_Identity=29.375, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4557235, Length=320, Percent_Identity=29.375, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI38505218, Length=310, Percent_Identity=25.8064516129032, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4503943, Length=297, Percent_Identity=27.6094276094276, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7669494, Length=220, Percent_Identity=30.9090909090909, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=400, Percent_Identity=22.5, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=405, Percent_Identity=22.7160493827161, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=26.7379679144385, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=255, Percent_Identity=29.8039215686275, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=419, Percent_Identity=24.8210023866348, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=357, Percent_Identity=27.4509803921569, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=251, Percent_Identity=29.8804780876494, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=351, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=210, Percent_Identity=29.5238095238095, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=201, Percent_Identity=31.8407960199005, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=28.8793103448276, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=209, Percent_Identity=27.7511961722488, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=255, Percent_Identity=27.843137254902, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=25.3623188405797, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=350, Percent_Identity=24.2857142857143, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=215, Percent_Identity=27.4418604651163, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=27.8551532033426, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355753, Length=282, Percent_Identity=31.2056737588652, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281363737, Length=321, Percent_Identity=29.2834890965732, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24666513, Length=348, Percent_Identity=26.4367816091954, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24660351, Length=345, Percent_Identity=27.536231884058, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646207, Length=359, Percent_Identity=27.2980501392758, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920834, Length=293, Percent_Identity=25.938566552901, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44281; Mature: 44281

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNYSPADDAFRADIRAWLEANLPDALRDKVLNHKRLNRDDYASWHALLGKRGWSAPAW
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCC
PAEYGGPNWNVTQRHIWDEECARLGAPTVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDG
CHHCCCCCCCCCHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHCCHHHHHHCCCHHCCC
SDWWCQGYSEPGSGSDLASLRTRAQRVGDHYVVNGQKTWTTLGQHADMMFCLVRTDSGAK
CCCEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCC
KQEGISFLLIDMKTPGITVRPIVTLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGHERTGIARVGQSKRELAFLKQLALNRKKNGKPLLHDPLFGAKVASLEIELMALEITVQ
HCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHH
RVVANEAGGRGPGPEASMLKIKGTEVQQGLTELMYEAVGPLAAPFDVPFLEGERAHSIAG
HHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLNYSPADDAFRADIRAWLEANLPDALRDKVLNHKRLNRDDYASWHALLGKRGWSAPAW
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCC
PAEYGGPNWNVTQRHIWDEECARLGAPTVLPFGVSMVAPVLMKYGSEAQKRRYLPRILDG
CHHCCCCCCCCCHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHCCHHHHHHCCCHHCCC
SDWWCQGYSEPGSGSDLASLRTRAQRVGDHYVVNGQKTWTTLGQHADMMFCLVRTDSGAK
CCCEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCC
KQEGISFLLIDMKTPGITVRPIVTLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYL
HHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGHERTGIARVGQSKRELAFLKQLALNRKKNGKPLLHDPLFGAKVASLEIELMALEITVQ
HCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHH
RVVANEAGGRGPGPEASMLKIKGTEVQQGLTELMYEAVGPLAAPFDVPFLEGERAHSIAG
HHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
DDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL
CCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]