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The map label for this gene is ndh [H]

Identifier: 186476585

GI number: 186476585

Start: 2088429

End: 2089781

Strand: Direct

Name: ndh [H]

Synonym: Bphy_1828

Alternate gene names: 186476585

Gene position: 2088429-2089781 (Clockwise)

Preceding gene: 186476583

Following gene: 186476587

Centisome position: 60.03

GC content: 65.41

Gene sequence:

>1353_bases
ATGACCACGATCGATCGACACACCGCAAGCAGCACACGCACTGCGCCACACCGGATCGTCATCGTTGGCGGCGGCGTGGG
TGGACTGGGACTCGCGACGCGTCTTGGCGAATCGCTCGGCAAGAGCGGACATGCGCAAGTCGTGCTGGTGGACCGCTCGC
CGACACACTTCTGGAAGCCGCTGTTGCACGAAGCCGCCTCCGGCCAGATCGACCCCGCCACGCATCAGCTGCAATATGCG
GTGCAGGCACGTCGTCACGGCTTTGCGTTCGAACAGGGCGCGCTGCAATCGCTCGATCGCGCGCAGCATCGCATCACGAT
CAGCGCGACGCGCGACGAAGACGGCCGCGACGTATTGCCCGCGCGTCACATCGAGTTCGACACCCTCGTGCTCGCACTCG
GCAGCGTGACGAACTACTTCGGCGTGAAAGGTGCGGCGGACCATGCGCTGCCGCTCGAGTCCGTCACACATGCGGAATCG
TTCCGACGCAAGCTGCTCGATGCGTGCACGCGAGCAAACCACGTGCGGCGCGTGAGCGGCGCGCAGCAGGTGCAGCCGGT
GTCGATCAACATCATCGGTGCGGGCGCGACAGGCGTCGAGCTCGCGGCCGCTTTGCGCGACAGCATCCGTTTGATGCATC
GCTATAGCCTCTTTGCACTCGACCCGGAGCGCGATTTCTGCATTCGCCTGATCGAAGGCACGGATCGCGTGTTGCCCGCG
CTGTCGCAGCGCGTTTCCATGCGTGCGCGGCGGATGCTGAGCGGCCTCGGCGTCGACGTGCTGACGACTACGCGCGTGAC
AGAAGTGCGCGCCGACGCTGTCTGGACGCACGACGGTCAGCAACTGCCCAACGATATCGCGATCTGGACAGCAGGCATCG
CCGGGCCGCCTGTGTTGCGCGTGCTCGACGGCATCGAGGTGAACCGCAACGCACAAGTGCTCGTGAGCCGCACGCTGCAA
ACCACGACGGATGAAAACGTCTTCGCATTGGGCGATTGCGCAGCCTGCCCTTCGCACGCGGATGGCTTCCTCGCACCACG
CGCGCAGGTCGCGCATCAACAGGCGACGTTTCTCGCGCGTGCGTTGAAGTGCCGTGTCGGCGGCGAAGCGCTGCCCGAGT
TCACGTATCGCGACGCGGGCACGCTGGTCGGTTTCGGCGACGTCGGCACGATCGGCAGTCTGAGCGGCTTGCGTGAACGG
CCCGTGTTCGTCGATGGCTGGCTCGCCACCATCGTGTACCGGCTGATCTATCGCCGGCACATGATGACCGTCAGCGGTTT
TGCGCGCATGGCGCTTGATACGGCGAGTCATTGGCTGCGTCGCCGCGTGCATCCCGTGATCCGGCTGCACTGA

Upstream 100 bases:

>100_bases
ACATTAAATTGTGCTGCGGTTTCCCCCAATTCTATACTCGACCTTACTGATGATGTTCACGCATGAATCGCATTGAAAAA
CGTTCAGGAGAGTACGCATC

Downstream 100 bases:

>100_bases
TTCACCTGGCACGCCGTCAAACGCGTGGCGCCAGCCGTCAGTCGAGAAACTCGGCGGACCTTTGGCGCAGCGCGGCGCTG
AACTCGTCCAGCCAGCCAAT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTTIDRHTASSTRTAPHRIVIVGGGVGGLGLATRLGESLGKSGHAQVVLVDRSPTHFWKPLLHEAASGQIDPATHQLQYA
VQARRHGFAFEQGALQSLDRAQHRITISATRDEDGRDVLPARHIEFDTLVLALGSVTNYFGVKGAADHALPLESVTHAES
FRRKLLDACTRANHVRRVSGAQQVQPVSINIIGAGATGVELAAALRDSIRLMHRYSLFALDPERDFCIRLIEGTDRVLPA
LSQRVSMRARRMLSGLGVDVLTTTRVTEVRADAVWTHDGQQLPNDIAIWTAGIAGPPVLRVLDGIEVNRNAQVLVSRTLQ
TTTDENVFALGDCAACPSHADGFLAPRAQVAHQQATFLARALKCRVGGEALPEFTYRDAGTLVGFGDVGTIGSLSGLRER
PVFVDGWLATIVYRLIYRRHMMTVSGFARMALDTASHWLRRRVHPVIRLH

Sequences:

>Translated_450_residues
MTTIDRHTASSTRTAPHRIVIVGGGVGGLGLATRLGESLGKSGHAQVVLVDRSPTHFWKPLLHEAASGQIDPATHQLQYA
VQARRHGFAFEQGALQSLDRAQHRITISATRDEDGRDVLPARHIEFDTLVLALGSVTNYFGVKGAADHALPLESVTHAES
FRRKLLDACTRANHVRRVSGAQQVQPVSINIIGAGATGVELAAALRDSIRLMHRYSLFALDPERDFCIRLIEGTDRVLPA
LSQRVSMRARRMLSGLGVDVLTTTRVTEVRADAVWTHDGQQLPNDIAIWTAGIAGPPVLRVLDGIEVNRNAQVLVSRTLQ
TTTDENVFALGDCAACPSHADGFLAPRAQVAHQQATFLARALKCRVGGEALPEFTYRDAGTLVGFGDVGTIGSLSGLRER
PVFVDGWLATIVYRLIYRRHMMTVSGFARMALDTASHWLRRRVHPVIRLH
>Mature_449_residues
TTIDRHTASSTRTAPHRIVIVGGGVGGLGLATRLGESLGKSGHAQVVLVDRSPTHFWKPLLHEAASGQIDPATHQLQYAV
QARRHGFAFEQGALQSLDRAQHRITISATRDEDGRDVLPARHIEFDTLVLALGSVTNYFGVKGAADHALPLESVTHAESF
RRKLLDACTRANHVRRVSGAQQVQPVSINIIGAGATGVELAAALRDSIRLMHRYSLFALDPERDFCIRLIEGTDRVLPAL
SQRVSMRARRMLSGLGVDVLTTTRVTEVRADAVWTHDGQQLPNDIAIWTAGIAGPPVLRVLDGIEVNRNAQVLVSRTLQT
TTDENVFALGDCAACPSHADGFLAPRAQVAHQQATFLARALKCRVGGEALPEFTYRDAGTLVGFGDVGTIGSLSGLRERP
VFVDGWLATIVYRLIYRRHMMTVSGFARMALDTASHWLRRRVHPVIRLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=39.63133640553, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6323794, Length=354, Percent_Identity=24.8587570621469, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323515, Length=468, Percent_Identity=23.7179487179487, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320118, Length=379, Percent_Identity=26.1213720316623, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49089; Mature: 48958

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIDRHTASSTRTAPHRIVIVGGGVGGLGLATRLGESLGKSGHAQVVLVDRSPTHFWKP
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LLHEAASGQIDPATHQLQYAVQARRHGFAFEQGALQSLDRAQHRITISATRDEDGRDVLP
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
ARHIEFDTLVLALGSVTNYFGVKGAADHALPLESVTHAESFRRKLLDACTRANHVRRVSG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQQVQPVSINIIGAGATGVELAAALRDSIRLMHRYSLFALDPERDFCIRLIEGTDRVLPA
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCCCHHHHHH
LSQRVSMRARRMLSGLGVDVLTTTRVTEVRADAVWTHDGQQLPNDIAIWTAGIAGPPVLR
HHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCEEEECCCCCCCCCEEEEECCCCCCHHHH
VLDGIEVNRNAQVLVSRTLQTTTDENVFALGDCAACPSHADGFLAPRAQVAHQQATFLAR
HHCCCCCCCCCEEEEEEHHHCCCCCCEEEEECHHCCCCCCCCCCCCHHHHHHHHHHHHHH
ALKCRVGGEALPEFTYRDAGTLVGFGDVGTIGSLSGLRERPVFVDGWLATIVYRLIYRRH
HHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
MMTVSGFARMALDTASHWLRRRVHPVIRLH
HHHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
TTIDRHTASSTRTAPHRIVIVGGGVGGLGLATRLGESLGKSGHAQVVLVDRSPTHFWKP
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LLHEAASGQIDPATHQLQYAVQARRHGFAFEQGALQSLDRAQHRITISATRDEDGRDVLP
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
ARHIEFDTLVLALGSVTNYFGVKGAADHALPLESVTHAESFRRKLLDACTRANHVRRVSG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AQQVQPVSINIIGAGATGVELAAALRDSIRLMHRYSLFALDPERDFCIRLIEGTDRVLPA
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCCCHHHHHH
LSQRVSMRARRMLSGLGVDVLTTTRVTEVRADAVWTHDGQQLPNDIAIWTAGIAGPPVLR
HHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCEEEECCCCCCCCCEEEEECCCCCCHHHH
VLDGIEVNRNAQVLVSRTLQTTTDENVFALGDCAACPSHADGFLAPRAQVAHQQATFLAR
HHCCCCCCCCCEEEEEEHHHCCCCCCEEEEECHHCCCCCCCCCCCCHHHHHHHHHHHHHH
ALKCRVGGEALPEFTYRDAGTLVGFGDVGTIGSLSGLRERPVFVDGWLATIVYRLIYRRH
HHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
MMTVSGFARMALDTASHWLRRRVHPVIRLH
HHHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]