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The map label for this gene is abgR [H]

Identifier: 186476583

GI number: 186476583

Start: 2086266

End: 2087216

Strand: Direct

Name: abgR [H]

Synonym: Bphy_1826

Alternate gene names: 186476583

Gene position: 2086266-2087216 (Clockwise)

Preceding gene: 186476580

Following gene: 186476585

Centisome position: 59.96

GC content: 64.88

Gene sequence:

>951_bases
ATGAAACTGCACCAGCTCACCACGCTCGCCGCCATCGCGGAGACAGGCAGTATTCGCGCCGCCGCGCGGCAGTTGGGGCT
CTCGCCCGCTGCCGTCACCAAGTCCGTGCGCGAACTCGAAGCGGACCTGCGCACGCCGCTCGTGATACGCGGCACGACGG
GGGTGGCGTTCACCGAATATGGCCGCGCGCTCGTCGTGCACGCGCGGCTCGTGCTGGGACAACTCGCGCGCGCCGAGGCC
GAACTCGAAGCGATGCGCGGCGCAGCGGCGGGCAAATTGTCGGTGGGCGTGACGCCGTGGCTCGCGCTGACGTTTCTGCC
CGAGACGGTCAATCGCTTCAAGCAGAGAATGCCCGACGTACAACTCGAATTCTTCGAAGGCTTACTGGCAGTCGTGCAGC
CGAGACTGCGCGACGGCAGCCTGGATTTTTCGATCGGCCGTCCGCCGCCGGCATCGCCGCAGTCGGAGTTTCATAACGTA
CCGCTCTTTTCGACGCATTCGGCCGTCGTCGCGCGACGCGGACATCCGCTCGCCGAATGCCGCACGCTGCACGATCTGCA
GGATGCGCAATGGGTGTTGAACTGGGACCCGGCGAGCCGGGAGTCGATGGCCGACAAGCTGTTCCGCAAGCGCGGCATGA
GAGTGCCGCACACGATCCATCTCGCGCATTCGTTCGCGATCGTACTCGGCCTGCTTCAGCAGACGGATTTCCTCAGCATC
TTTCCGTGGCCGCTCGTCGAAGTGAACATCGCGAAGGAGAATCTGCGCGCGTTGCCGCTGCGCGAGGTGGTGGACGAGAC
GACGGTCAGCATCACGTCGCGGCGGGGCGTGCCCGTCAGCCCGGCGGGTGCATGCTTTATCGAATGTCTGCGTGAAGTGA
TCGACGAAGGCGCACGATCGCAGGACGCCGACCGCCGCCGTCTGTTTCATTCGATCGAACTGCTGTTTTAG

Upstream 100 bases:

>100_bases
AACCCAGCATAGCCAACCGTTTTTTTGACGGGCAGGCGGGAAACGGTTACGGTGGCAACCAGCAGTTGCCGCCCGCGATG
CCAGCCTTCATTTGTCAGAT

Downstream 100 bases:

>100_bases
GCCTTGTTTCATGGACTATTCCGCCTAACCGGCCACGCCTCGATCGCGAGACAATCTTCGAGACCGAACTCGCCGTACTC
GCGTCCGTTTCCCGATTGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKLHQLTTLAAIAETGSIRAAARQLGLSPAAVTKSVRELEADLRTPLVIRGTTGVAFTEYGRALVVHARLVLGQLARAEA
ELEAMRGAAAGKLSVGVTPWLALTFLPETVNRFKQRMPDVQLEFFEGLLAVVQPRLRDGSLDFSIGRPPPASPQSEFHNV
PLFSTHSAVVARRGHPLAECRTLHDLQDAQWVLNWDPASRESMADKLFRKRGMRVPHTIHLAHSFAIVLGLLQQTDFLSI
FPWPLVEVNIAKENLRALPLREVVDETTVSITSRRGVPVSPAGACFIECLREVIDEGARSQDADRRRLFHSIELLF

Sequences:

>Translated_316_residues
MKLHQLTTLAAIAETGSIRAAARQLGLSPAAVTKSVRELEADLRTPLVIRGTTGVAFTEYGRALVVHARLVLGQLARAEA
ELEAMRGAAAGKLSVGVTPWLALTFLPETVNRFKQRMPDVQLEFFEGLLAVVQPRLRDGSLDFSIGRPPPASPQSEFHNV
PLFSTHSAVVARRGHPLAECRTLHDLQDAQWVLNWDPASRESMADKLFRKRGMRVPHTIHLAHSFAIVLGLLQQTDFLSI
FPWPLVEVNIAKENLRALPLREVVDETTVSITSRRGVPVSPAGACFIECLREVIDEGARSQDADRRRLFHSIELLF
>Mature_316_residues
MKLHQLTTLAAIAETGSIRAAARQLGLSPAAVTKSVRELEADLRTPLVIRGTTGVAFTEYGRALVVHARLVLGQLARAEA
ELEAMRGAAAGKLSVGVTPWLALTFLPETVNRFKQRMPDVQLEFFEGLLAVVQPRLRDGSLDFSIGRPPPASPQSEFHNV
PLFSTHSAVVARRGHPLAECRTLHDLQDAQWVLNWDPASRESMADKLFRKRGMRVPHTIHLAHSFAIVLGLLQQTDFLSI
FPWPLVEVNIAKENLRALPLREVVDETTVSITSRRGVPVSPAGACFIECLREVIDEGARSQDADRRRLFHSIELLF

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=291, Percent_Identity=28.5223367697594, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789506, Length=306, Percent_Identity=24.8366013071895, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=27.5, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081904, Length=293, Percent_Identity=25.2559726962457, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=24.3243243243243, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=297, Percent_Identity=23.9057239057239, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786401, Length=208, Percent_Identity=26.4423076923077, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790262, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=217, Percent_Identity=24.8847926267281, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787949, Length=177, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789440, Length=147, Percent_Identity=29.9319727891156, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=153, Percent_Identity=27.4509803921569, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=144, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=27.3972602739726, Blast_Score=61, Evalue=1e-10,
Organism=Escherichia coli, GI1787806, Length=291, Percent_Identity=23.0240549828179, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34949; Mature: 34949

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHQLTTLAAIAETGSIRAAARQLGLSPAAVTKSVRELEADLRTPLVIRGTTGVAFTEY
CCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHH
GRALVVHARLVLGQLARAEAELEAMRGAAAGKLSVGVTPWLALTFLPETVNRFKQRMPDV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCC
QLEFFEGLLAVVQPRLRDGSLDFSIGRPPPASPQSEFHNVPLFSTHSAVVARRGHPLAEC
HHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHH
RTLHDLQDAQWVLNWDPASRESMADKLFRKRGMRVPHTIHLAHSFAIVLGLLQQTDFLSI
HHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
FPWPLVEVNIAKENLRALPLREVVDETTVSITSRRGVPVSPAGACFIECLREVIDEGARS
CCCCEEEEEECHHHHHCCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
QDADRRRLFHSIELLF
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLHQLTTLAAIAETGSIRAAARQLGLSPAAVTKSVRELEADLRTPLVIRGTTGVAFTEY
CCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHH
GRALVVHARLVLGQLARAEAELEAMRGAAAGKLSVGVTPWLALTFLPETVNRFKQRMPDV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCC
QLEFFEGLLAVVQPRLRDGSLDFSIGRPPPASPQSEFHNVPLFSTHSAVVARRGHPLAEC
HHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHH
RTLHDLQDAQWVLNWDPASRESMADKLFRKRGMRVPHTIHLAHSFAIVLGLLQQTDFLSI
HHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
FPWPLVEVNIAKENLRALPLREVVDETTVSITSRRGVPVSPAGACFIECLREVIDEGARS
CCCCEEEEEECHHHHHCCCHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
QDADRRRLFHSIELLF
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]