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The map label for this gene is argD [H]

Identifier: 186476545

GI number: 186476545

Start: 2042581

End: 2043810

Strand: Reverse

Name: argD [H]

Synonym: Bphy_1787

Alternate gene names: 186476545

Gene position: 2043810-2042581 (Counterclockwise)

Preceding gene: 186476546

Following gene: 186476544

Centisome position: 58.74

GC content: 63.41

Gene sequence:

>1230_bases
ATGAACGACCAGAATGTGACCCGCCAGACTTTCGACGAAGTCATGGTCCCTGTTTTCTCGCCGGCGTCCTTCGTCCCCGA
TCGGGGGCAAGGCTCTCGTGTATGGGACACGCAAGGCAAGGATTACGTCGACTTCGCGGGCGGCATCGCCGTCACGGCCC
TCGGTCACGGCCATCCCGAACTGATGAAGGTTCTGCACGAGCAGGGCGCCAAACTCTGGCACATCGGTAATGGTTACACC
AATGAACCCGTGCTGCGTCTCGCGAAGCGCCTCGAGGAACTCACCTTCGCCGAGCGCGCGTTCTTCGCGAATTCGGGCGC
CGAAGCCAACGAAGCGGCGCTCAAGCTTGCGCGCCGCGTCGCCTTCGACCGTCATGGTGCCGACAAGTACGAAATCATCT
CGTTCACGCAGTCGTTTCACGGCCGCACCTTCTTCACGGTGAGCGTCGGCGGCCAGCCGAAGTACTCGGAAGGCTTCGGA
CCCGTGCCCGCAGGCATCAGGCATCTGCCGTACAACGACATCGCAGCCGCACGCGCCGCCATCGGTCCGAAGACCTGCGC
CGTCATCGTCGAGCCGGTGCAGGGCGAAGGCGGCGTGATTCCCGCCGATCCCGCCTTCCTCAAGGCGTTGCGTGAAGCCT
GCGACCAGCACGGCGCACTGCTGATTTTCGACGAGGTGCAAACGGGCGTCGGCCGCACGGGCTTCTTCTACGCATACCAG
GACACGGGCGTGACGCCCGACATCCTGACGACGGCCAAGGCACTCGGCAACGGCTTCCCGATCGGCGCAATGCTGACCAC
GAACGAACTCGCCGCGCATTTCAAGGTCGGCGTGCACGGCACGACGTATGGCGGCAATCCCCTCGCAACCGCGATCGCGC
TGAAGGTGGTCGATCTCGTCAGCGACCCGAAGCTGCTCGAAGGCGTGCGCACGCGCAGCGAACAGCTGAAAGCGAAGCTC
GCGAAGATCAACGAACGCTTCGGCATCTTCAGTGACGTGCGCGGCAAAGGCCTGCTGATCGGCGCCGAACTTACGGATGC
CTATAAGGGCCGCGCGAAAGACTTCGTGACGGCGGCTGGCAAGCATGGCGTGATCATGCTGATGGCGGGTCCGGACGTGC
TGCGTTTCGCGCCGTCGCTGATCATTCCCGTCGACGACATGAACGACGGCCTTGCGCGCTTCGAAAAAGCTGTCGAGGAA
GTCGTCGGCGCCGTCGCAATCGCCAAGTAA

Upstream 100 bases:

>100_bases
GCAGACATAAAAAAAGAACCCGTCGCTTCCACGCAAGAACATCCCCCCACTGTCACCTAAACTACGGATCATTACTCTGA
ACGAGCCTCGAGGATCCACC

Downstream 100 bases:

>100_bases
CTCGCCCCTCTCCACACACGAGACCACGATGCTCTTCGTCCGCCCAGGCCGTCTGGCCGATCTCGACGCGTTGCAACAGA
TGGCGCGCAACGCGCAGCCC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNDQNVTRQTFDEVMVPVFSPASFVPDRGQGSRVWDTQGKDYVDFAGGIAVTALGHGHPELMKVLHEQGAKLWHIGNGYT
NEPVLRLAKRLEELTFAERAFFANSGAEANEAALKLARRVAFDRHGADKYEIISFTQSFHGRTFFTVSVGGQPKYSEGFG
PVPAGIRHLPYNDIAAARAAIGPKTCAVIVEPVQGEGGVIPADPAFLKALREACDQHGALLIFDEVQTGVGRTGFFYAYQ
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLATAIALKVVDLVSDPKLLEGVRTRSEQLKAKL
AKINERFGIFSDVRGKGLLIGAELTDAYKGRAKDFVTAAGKHGVIMLMAGPDVLRFAPSLIIPVDDMNDGLARFEKAVEE
VVGAVAIAK

Sequences:

>Translated_409_residues
MNDQNVTRQTFDEVMVPVFSPASFVPDRGQGSRVWDTQGKDYVDFAGGIAVTALGHGHPELMKVLHEQGAKLWHIGNGYT
NEPVLRLAKRLEELTFAERAFFANSGAEANEAALKLARRVAFDRHGADKYEIISFTQSFHGRTFFTVSVGGQPKYSEGFG
PVPAGIRHLPYNDIAAARAAIGPKTCAVIVEPVQGEGGVIPADPAFLKALREACDQHGALLIFDEVQTGVGRTGFFYAYQ
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLATAIALKVVDLVSDPKLLEGVRTRSEQLKAKL
AKINERFGIFSDVRGKGLLIGAELTDAYKGRAKDFVTAAGKHGVIMLMAGPDVLRFAPSLIIPVDDMNDGLARFEKAVEE
VVGAVAIAK
>Mature_409_residues
MNDQNVTRQTFDEVMVPVFSPASFVPDRGQGSRVWDTQGKDYVDFAGGIAVTALGHGHPELMKVLHEQGAKLWHIGNGYT
NEPVLRLAKRLEELTFAERAFFANSGAEANEAALKLARRVAFDRHGADKYEIISFTQSFHGRTFFTVSVGGQPKYSEGFG
PVPAGIRHLPYNDIAAARAAIGPKTCAVIVEPVQGEGGVIPADPAFLKALREACDQHGALLIFDEVQTGVGRTGFFYAYQ
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLATAIALKVVDLVSDPKLLEGVRTRSEQLKAKL
AKINERFGIFSDVRGKGLLIGAELTDAYKGRAKDFVTAAGKHGVIMLMAGPDVLRFAPSLIIPVDDMNDGLARFEKAVEE
VVGAVAIAK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=32.8125, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.4515050167224, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=424, Percent_Identity=30.6603773584906, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=28.7081339712919, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24119277, Length=407, Percent_Identity=27.027027027027, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=28.8265306122449, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=28.2296650717703, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=23.855421686747, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=23.855421686747, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=23.855421686747, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=61.5, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=60.4010025062657, Blast_Score=512, Evalue=1e-146,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=35.4368932038835, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=33.8422391857506, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1787560, Length=413, Percent_Identity=31.9612590799031, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1786349, Length=340, Percent_Identity=33.5294117647059, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=29.7101449275362, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=368, Percent_Identity=35.054347826087, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=30.5882352941176, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=258, Percent_Identity=35.6589147286822, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=27.3170731707317, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=162, Percent_Identity=32.0987654320988, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=412, Percent_Identity=25.2427184466019, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=38.1313131313131, Blast_Score=269, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=34.2364532019704, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=358, Percent_Identity=27.0949720670391, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=377, Percent_Identity=25.7294429708223, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=31.7708333333333, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=30.4038004750594, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=30.0469483568075, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=29.3556085918854, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281366494, Length=437, Percent_Identity=25.4004576659039, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24667139, Length=437, Percent_Identity=25.4004576659039, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24667143, Length=437, Percent_Identity=25.4004576659039, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43821; Mature: 43821

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQNVTRQTFDEVMVPVFSPASFVPDRGQGSRVWDTQGKDYVDFAGGIAVTALGHGHPE
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCHH
LMKVLHEQGAKLWHIGNGYTNEPVLRLAKRLEELTFAERAFFANSGAEANEAALKLARRV
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFDRHGADKYEIISFTQSFHGRTFFTVSVGGQPKYSEGFGPVPAGIRHLPYNDIAAARAA
HHHCCCCCCEEEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IGPKTCAVIVEPVQGEGGVIPADPAFLKALREACDQHGALLIFDEVQTGVGRTGFFYAYQ
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCEEEEEEE
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLATAIALKVVDLV
CCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHEEEEEECCEECCCCCHHHHHHHHHHHHHH
SDPKLLEGVRTRSEQLKAKLAKINERFGIFSDVRGKGLLIGAELTDAYKGRAKDFVTAAG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEECCHHHHHCCCHHHHHHCCC
KHGVIMLMAGPDVLRFAPSLIIPVDDMNDGLARFEKAVEEVVGAVAIAK
CCCEEEEEECCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDQNVTRQTFDEVMVPVFSPASFVPDRGQGSRVWDTQGKDYVDFAGGIAVTALGHGHPE
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCHH
LMKVLHEQGAKLWHIGNGYTNEPVLRLAKRLEELTFAERAFFANSGAEANEAALKLARRV
HHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFDRHGADKYEIISFTQSFHGRTFFTVSVGGQPKYSEGFGPVPAGIRHLPYNDIAAARAA
HHHCCCCCCEEEEEHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
IGPKTCAVIVEPVQGEGGVIPADPAFLKALREACDQHGALLIFDEVQTGVGRTGFFYAYQ
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCEEEEEEE
DTGVTPDILTTAKALGNGFPIGAMLTTNELAAHFKVGVHGTTYGGNPLATAIALKVVDLV
CCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHEEEEEECCEECCCCCHHHHHHHHHHHHHH
SDPKLLEGVRTRSEQLKAKLAKINERFGIFSDVRGKGLLIGAELTDAYKGRAKDFVTAAG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEECCHHHHHCCCHHHHHHCCC
KHGVIMLMAGPDVLRFAPSLIIPVDDMNDGLARFEKAVEEVVGAVAIAK
CCCEEEEEECCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]