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The map label for this gene is mdtA [H]

Identifier: 186476529

GI number: 186476529

Start: 2018795

End: 2020204

Strand: Direct

Name: mdtA [H]

Synonym: Bphy_1771

Alternate gene names: 186476529

Gene position: 2018795-2020204 (Clockwise)

Preceding gene: 186476527

Following gene: 186476530

Centisome position: 58.02

GC content: 65.39

Gene sequence:

>1410_bases
ATGGACGAACAAAAAAAGCAGCCTGAATCATCACGCCACACCGAACCCGCCAGCCCGTCTCCCGGGCGCGAACCGGGGCC
TGGTGCCGTCAAGCGCCATCGCGGACGTACGATCGCGTTGATCGTCGCCGTCATGCTGTTCGCGGGCTTCGTGCTGCTGC
GCTGGCATCCGTGGAACGCAAGCGCGGACGGCGCGAGCGCGGCGGCGGCGGGCGCAAGCGGCGTACAGGCGGGACGCGCC
GGACGACGTGGCAGCGGGCCCGGCGGCGGCATGAACCAGCCGCAACCCGTACACGTGGCGGCCGCGACGCAAGGCGAAAT
GCCCGTCGTGCTGAACGCGCTCGGAACCGTCACCCCGCTCGCCAACGTCACCGTACGCACGCAGTTGTCGGGCACGCTGC
AGACGGTCGCGTTTCAGGAAGGCCAGATGGTCAAGCGCGGCGATCTGCTTGCGCAGGTCGACCCACGTCCGTATCAGATC
AGTCTTGCGAATGCCGAAGGCACGCTCGCCAAGGACATCGCGCTGCTGCAAACTGCCCGTCTCGATCTGAAGCGCTATCA
GACGCTCCTCTCGCAAGACTCAATCGCGAGCCAGCAGGTCGATACGCAGGCGTCGCTCGTCAAGCAGTACGAAGGCCAGG
TCAAGGCTGACCAGGCGAATATCGACACCTTCAAACTCGATCTCACCTACGCGCGCATCACGGCGCCCGTATCGGGCCGC
GTCGGTCTGCGTCAGGTCGATGCCGGCAACTACGTGACGCCGAGCGATACGAACGGCGTCGTCGTGATCACGCAGTTGCA
ACCGATCAGCGTTATCTTCACCACTTCCGAAGACAACCTGCCCGCCATCCTCAAGCAGTTGCGCACGGGCCAGAAGATGT
CGGTGACGGCCTACGACCGCAGCAACACGACCTCGCTCGAAGCGGGCTATCTGGAAACGCTGGACAACCAGATCGACACG
ACGACGGGCACCGTAAAGCTACGCGCCACGTTTCAGAACAACAGCGGGCTGCTGTTCCCGAATCAGTTCGTCAATACGCG
CCTGCTCGTGAACGTGGTGAAGGACGCGGTGATCGTGCCGACCTCGTCGGTGCTGAACGGCTCGATGGGTGCGTTCGTGT
ACGTCGTGAAGCCTGACAACACGGTGACGGTGCGCAAGGTCAAGGTCGGCCCCGTCGACGGCGAGCGCACCAGCATCGCG
TCGGGTCTGCAGGTCGGTGAGCGCGTCGTGACCGACGGCTCGGACCGGCTGAAGGAAGGCGCAAAGATCACGATTCCCGC
CGACCGTCCGCGCGGCGCGTCGGGTGCCTCGGGTGCGCACGCGGCATCGGGTGCTCCTCCCGCGGCGAACGCTAACGGCG
CATCGGGCGCGCGGCGTCATCGACACGCGTCGCAGACGTCGGCGGAATAA

Upstream 100 bases:

>100_bases
ATCGCCCAGGCATGCGCTATCGACGGAACCGGCGTGCAGTACGCAGCCACGGCGCGCGCCGAACGTTTGCTTCATTTCAA
GCCAGCCACTGATCGAACCG

Downstream 100 bases:

>100_bases
GGCACGGCTGACCGCATGAATCCATCCCGCGCCTTTATTCTGCGCCCGGTCGGCACCGCCCTTCTGATGGCGGCGATCAT
GCTGGTCGGGCTCGTCGCGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MDEQKKQPESSRHTEPASPSPGREPGPGAVKRHRGRTIALIVAVMLFAGFVLLRWHPWNASADGASAAAAGASGVQAGRA
GRRGSGPGGGMNQPQPVHVAAATQGEMPVVLNALGTVTPLANVTVRTQLSGTLQTVAFQEGQMVKRGDLLAQVDPRPYQI
SLANAEGTLAKDIALLQTARLDLKRYQTLLSQDSIASQQVDTQASLVKQYEGQVKADQANIDTFKLDLTYARITAPVSGR
VGLRQVDAGNYVTPSDTNGVVVITQLQPISVIFTTSEDNLPAILKQLRTGQKMSVTAYDRSNTTSLEAGYLETLDNQIDT
TTGTVKLRATFQNNSGLLFPNQFVNTRLLVNVVKDAVIVPTSSVLNGSMGAFVYVVKPDNTVTVRKVKVGPVDGERTSIA
SGLQVGERVVTDGSDRLKEGAKITIPADRPRGASGASGAHAASGAPPAANANGASGARRHRHASQTSAE

Sequences:

>Translated_469_residues
MDEQKKQPESSRHTEPASPSPGREPGPGAVKRHRGRTIALIVAVMLFAGFVLLRWHPWNASADGASAAAAGASGVQAGRA
GRRGSGPGGGMNQPQPVHVAAATQGEMPVVLNALGTVTPLANVTVRTQLSGTLQTVAFQEGQMVKRGDLLAQVDPRPYQI
SLANAEGTLAKDIALLQTARLDLKRYQTLLSQDSIASQQVDTQASLVKQYEGQVKADQANIDTFKLDLTYARITAPVSGR
VGLRQVDAGNYVTPSDTNGVVVITQLQPISVIFTTSEDNLPAILKQLRTGQKMSVTAYDRSNTTSLEAGYLETLDNQIDT
TTGTVKLRATFQNNSGLLFPNQFVNTRLLVNVVKDAVIVPTSSVLNGSMGAFVYVVKPDNTVTVRKVKVGPVDGERTSIA
SGLQVGERVVTDGSDRLKEGAKITIPADRPRGASGASGAHAASGAPPAANANGASGARRHRHASQTSAE
>Mature_469_residues
MDEQKKQPESSRHTEPASPSPGREPGPGAVKRHRGRTIALIVAVMLFAGFVLLRWHPWNASADGASAAAAGASGVQAGRA
GRRGSGPGGGMNQPQPVHVAAATQGEMPVVLNALGTVTPLANVTVRTQLSGTLQTVAFQEGQMVKRGDLLAQVDPRPYQI
SLANAEGTLAKDIALLQTARLDLKRYQTLLSQDSIASQQVDTQASLVKQYEGQVKADQANIDTFKLDLTYARITAPVSGR
VGLRQVDAGNYVTPSDTNGVVVITQLQPISVIFTTSEDNLPAILKQLRTGQKMSVTAYDRSNTTSLEAGYLETLDNQIDT
TTGTVKLRATFQNNSGLLFPNQFVNTRLLVNVVKDAVIVPTSSVLNGSMGAFVYVVKPDNTVTVRKVKVGPVDGERTSIA
SGLQVGERVVTDGSDRLKEGAKITIPADRPRGASGASGAHAASGAPPAANANGASGARRHRHASQTSAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=374, Percent_Identity=45.1871657754011, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1789929, Length=333, Percent_Identity=29.1291291291291, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1786668, Length=389, Percent_Identity=29.5629820051414, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789665, Length=319, Percent_Identity=31.3479623824451, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081796, Length=349, Percent_Identity=26.3610315186246, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=30.2197802197802, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49320; Mature: 49320

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQKKQPESSRHTEPASPSPGREPGPGAVKRHRGRTIALIVAVMLFAGFVLLRWHPWNA
CCCHHCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCEEEEEEECCCC
SADGASAAAAGASGVQAGRAGRRGSGPGGGMNQPQPVHVAAATQGEMPVVLNALGTVTPL
CCCCCCHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCC
ANVTVRTQLSGTLQTVAFQEGQMVKRGDLLAQVDPRPYQISLANAEGTLAKDIALLQTAR
CCEEEEEECCCCEEEEEECCCCEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
LDLKRYQTLLSQDSIASQQVDTQASLVKQYEGQVKADQANIDTFKLDLTYARITAPVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEEEECCCCCC
VGLRQVDAGNYVTPSDTNGVVVITQLQPISVIFTTSEDNLPAILKQLRTGQKMSVTAYDR
CCEEEECCCCEECCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECC
SNTTSLEAGYLETLDNQIDTTTGTVKLRATFQNNSGLLFPNQFVNTRLLVNVVKDAVIVP
CCCCEECCHHHHHHCCCCCCCCCEEEEEEEEECCCCEECCHHHHHHHHHHHHHHCEEEEC
TSSVLNGSMGAFVYVVKPDNTVTVRKVKVGPVDGERTSIASGLQVGERVVTDGSDRLKEG
CHHHHCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCC
AKITIPADRPRGASGASGAHAASGAPPAANANGASGARRHRHASQTSAE
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MDEQKKQPESSRHTEPASPSPGREPGPGAVKRHRGRTIALIVAVMLFAGFVLLRWHPWNA
CCCHHCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCEEEEEEECCCC
SADGASAAAAGASGVQAGRAGRRGSGPGGGMNQPQPVHVAAATQGEMPVVLNALGTVTPL
CCCCCCHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCC
ANVTVRTQLSGTLQTVAFQEGQMVKRGDLLAQVDPRPYQISLANAEGTLAKDIALLQTAR
CCEEEEEECCCCEEEEEECCCCEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
LDLKRYQTLLSQDSIASQQVDTQASLVKQYEGQVKADQANIDTFKLDLTYARITAPVSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEEEEEEEECCCCCC
VGLRQVDAGNYVTPSDTNGVVVITQLQPISVIFTTSEDNLPAILKQLRTGQKMSVTAYDR
CCEEEECCCCEECCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECC
SNTTSLEAGYLETLDNQIDTTTGTVKLRATFQNNSGLLFPNQFVNTRLLVNVVKDAVIVP
CCCCEECCHHHHHHCCCCCCCCCEEEEEEEEECCCCEECCHHHHHHHHHHHHHHCEEEEC
TSSVLNGSMGAFVYVVKPDNTVTVRKVKVGPVDGERTSIASGLQVGERVVTDGSDRLKEG
CHHHHCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCC
AKITIPADRPRGASGASGAHAASGAPPAANANGASGARRHRHASQTSAE
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA