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The map label for this gene is mdtP [H]

Identifier: 186476482

GI number: 186476482

Start: 1965222

End: 1966769

Strand: Direct

Name: mdtP [H]

Synonym: Bphy_1724

Alternate gene names: 186476482

Gene position: 1965222-1966769 (Clockwise)

Preceding gene: 186476481

Following gene: 186476483

Centisome position: 56.49

GC content: 65.83

Gene sequence:

>1548_bases
ATGTCATTACACGCAAAGAGTCGAGCGATGAACTTCCTTCCTTGGCCCGCGCCTGCCTCGTCACACCGGGCGGCCGTCGC
TGCAGCCGTGGCGGCGTTCGCCCTCGCCGGCTGCGCGAACTACTTCGATCTCAAGGACGACAGGCAGATCGCGTCGACCT
CGCAGTTCGAGGCGTCACAGAGCCTGCCCGCGCAAGGCGGCCAATGGCCGGCGCTCGACTGGGCGAACCAGTTCGGCGAT
CCGCAACTGCCGAAGCTGATCGCGGAAGCGCTCGAAGGCAATCCGTCAATCGCGCAGGCGCAGGCGCGCATCGCGAAGGC
GTCGTCCTATATCGAAACCTCGAAGTCGGCGCTCTATCCGAAGGTCGAGGGCAGCTATTCGTGGACCCGCGAGCTGTACT
CTGCCAATGCGCTGTTTCCGCCGCCGTACGGCGGCACGTGGTACAGCGAGAACAATGTGCTCGCCAGCGCGTCGTGGGAT
CTCGACTTGTGGGGTAAGAACCGGGAACGGCTCGGCCAGGCTGTGTCGCAGGAAAAAGCTGCCGAAGCCGACATGCAGCA
GGCCCGCGTGACCCTCGCCGCGTCGGTCGCGCGTACCTACAACTCGCTCGCGCAGCTGTACGCGCTGCGCGACATCGCCG
AGCGCGAAATCAAGAACCGCCAGACGATCGGCGCGATCACGAACGACCGCGTGCGGGCCGGCCTCGACACGAACGTCGAG
CGTCAGACGGCCAATGGCAACATCGCGACCAGTCAGTCGAACCTGACGGAGCTGGACGGCCAGATCACGAGCACGCGCTA
CGAACTCGGCACGCTGCTCGGCAAAGGGCCTGACCGCGGCCTGCAGATCGCCATGCCGGTGTTCGATCCCGGCAGCGCCG
TTTCGCTGCCCGACAACGTGCCCGCCGACCTCGTGTCGCGCCGGCCGGACATCGTCGCCGCGCGCTGGCAGGTCGAAGCC
GCGATGCACAACGTGAAGGAAGCCAAGGCCGAGTTTTTTCCTGACGTGAATCTCGCGGCCGCGTTCGGCTTCGACGCGTT
CGGCTGGAGCAAATTTCTGACGTCGTCGAGCCGTCAGATCCAGTTCGGGCCGGCCATCCATCTGCCGATTTTCGATGCCG
GCGCGCTGCGCTCGCAGCTCAAGGGCCGCTTCGCCGATTTCGACCTCGACGTCGCGAACTACAACCAGACGCTGATCGGC
GCGCTCTCCGACGTCGCCACGCAGATTTCGTCGATCCGTTCCATCGACAGGCAGGCGGGCGACGCACAGCGCGCGCTCGA
TGCATCGACGAAAGCGTACGAACTCGCCGTGATCCGCTACAAGGCCGGTTTGTCGCCGCAGTTGCAGGTACTGACGGCCG
ACCAGAACCGCCTCGCTGCCGAGCAGACGGTGACGAACCTCAAGATGCGCCGGCGCGATCTGCAATTCGCGCTGATCAAG
GCGCTCGGCGGCGGTTTCGACGCGACGCAGACGGGCCTCGTCGTGCCGACGGATACGCCTCCTGCATCGTCGGCAGCTGC
GGCGCCGGCAACGCACGCGGCGAACTAG

Upstream 100 bases:

>100_bases
TGGCCAATAGCTGCGAAGCGTATGGCGAAACCCGTGACTCGGCAAGCAATACCGATAGCAAATCGTAAGAAATTAATTGC
ATCGTCCATTAAAGAACTAC

Downstream 100 bases:

>100_bases
CGCGACAGTGACAAGACCACACGCACACCCGATTGCGATCCGAATAAACGATACAGACTGACAGAATCCGGAGCATATTC
ATGAGCACGCCCCAACAACC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MSLHAKSRAMNFLPWPAPASSHRAAVAAAVAAFALAGCANYFDLKDDRQIASTSQFEASQSLPAQGGQWPALDWANQFGD
PQLPKLIAEALEGNPSIAQAQARIAKASSYIETSKSALYPKVEGSYSWTRELYSANALFPPPYGGTWYSENNVLASASWD
LDLWGKNRERLGQAVSQEKAAEADMQQARVTLAASVARTYNSLAQLYALRDIAEREIKNRQTIGAITNDRVRAGLDTNVE
RQTANGNIATSQSNLTELDGQITSTRYELGTLLGKGPDRGLQIAMPVFDPGSAVSLPDNVPADLVSRRPDIVAARWQVEA
AMHNVKEAKAEFFPDVNLAAAFGFDAFGWSKFLTSSSRQIQFGPAIHLPIFDAGALRSQLKGRFADFDLDVANYNQTLIG
ALSDVATQISSIRSIDRQAGDAQRALDASTKAYELAVIRYKAGLSPQLQVLTADQNRLAAEQTVTNLKMRRRDLQFALIK
ALGGGFDATQTGLVVPTDTPPASSAAAAPATHAAN

Sequences:

>Translated_515_residues
MSLHAKSRAMNFLPWPAPASSHRAAVAAAVAAFALAGCANYFDLKDDRQIASTSQFEASQSLPAQGGQWPALDWANQFGD
PQLPKLIAEALEGNPSIAQAQARIAKASSYIETSKSALYPKVEGSYSWTRELYSANALFPPPYGGTWYSENNVLASASWD
LDLWGKNRERLGQAVSQEKAAEADMQQARVTLAASVARTYNSLAQLYALRDIAEREIKNRQTIGAITNDRVRAGLDTNVE
RQTANGNIATSQSNLTELDGQITSTRYELGTLLGKGPDRGLQIAMPVFDPGSAVSLPDNVPADLVSRRPDIVAARWQVEA
AMHNVKEAKAEFFPDVNLAAAFGFDAFGWSKFLTSSSRQIQFGPAIHLPIFDAGALRSQLKGRFADFDLDVANYNQTLIG
ALSDVATQISSIRSIDRQAGDAQRALDASTKAYELAVIRYKAGLSPQLQVLTADQNRLAAEQTVTNLKMRRRDLQFALIK
ALGGGFDATQTGLVVPTDTPPASSAAAAPATHAAN
>Mature_514_residues
SLHAKSRAMNFLPWPAPASSHRAAVAAAVAAFALAGCANYFDLKDDRQIASTSQFEASQSLPAQGGQWPALDWANQFGDP
QLPKLIAEALEGNPSIAQAQARIAKASSYIETSKSALYPKVEGSYSWTRELYSANALFPPPYGGTWYSENNVLASASWDL
DLWGKNRERLGQAVSQEKAAEADMQQARVTLAASVARTYNSLAQLYALRDIAEREIKNRQTIGAITNDRVRAGLDTNVER
QTANGNIATSQSNLTELDGQITSTRYELGTLLGKGPDRGLQIAMPVFDPGSAVSLPDNVPADLVSRRPDIVAARWQVEAA
MHNVKEAKAEFFPDVNLAAAFGFDAFGWSKFLTSSSRQIQFGPAIHLPIFDAGALRSQLKGRFADFDLDVANYNQTLIGA
LSDVATQISSIRSIDRQAGDAQRALDASTKAYELAVIRYKAGLSPQLQVLTADQNRLAAEQTVTNLKMRRRDLQFALIKA
LGGGFDATQTGLVVPTDTPPASSAAAAPATHAAN

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=464, Percent_Identity=30.3879310344828, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1786785, Length=468, Percent_Identity=28.4188034188034, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 55417; Mature: 55286

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHAKSRAMNFLPWPAPASSHRAAVAAAVAAFALAGCANYFDLKDDRQIASTSQFEASQ
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
SLPAQGGQWPALDWANQFGDPQLPKLIAEALEGNPSIAQAQARIAKASSYIETSKSALYP
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KVEGSYSWTRELYSANALFPPPYGGTWYSENNVLASASWDLDLWGKNRERLGQAVSQEKA
CCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEEECCCCEEECCCCHHHHHHHHHHHHH
AEADMQQARVTLAASVARTYNSLAQLYALRDIAEREIKNRQTIGAITNDRVRAGLDTNVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHCCCCCCCC
RQTANGNIATSQSNLTELDGQITSTRYELGTLLGKGPDRGLQIAMPVFDPGSAVSLPDNV
CCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCC
PADLVSRRPDIVAARWQVEAAMHNVKEAKAEFFPDVNLAAAFGFDAFGWSKFLTSSSRQI
CHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCCEE
QFGPAIHLPIFDAGALRSQLKGRFADFDLDVANYNQTLIGALSDVATQISSIRSIDRQAG
EECCEEEECCCCHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DAQRALDASTKAYELAVIRYKAGLSPQLQVLTADQNRLAAEQTVTNLKMRRRDLQFALIK
HHHHHHHCCCCEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGGGFDATQTGLVVPTDTPPASSAAAAPATHAAN
HHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLHAKSRAMNFLPWPAPASSHRAAVAAAVAAFALAGCANYFDLKDDRQIASTSQFEASQ
CCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
SLPAQGGQWPALDWANQFGDPQLPKLIAEALEGNPSIAQAQARIAKASSYIETSKSALYP
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KVEGSYSWTRELYSANALFPPPYGGTWYSENNVLASASWDLDLWGKNRERLGQAVSQEKA
CCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEEECCCCEEECCCCHHHHHHHHHHHHH
AEADMQQARVTLAASVARTYNSLAQLYALRDIAEREIKNRQTIGAITNDRVRAGLDTNVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHCCCCCCCC
RQTANGNIATSQSNLTELDGQITSTRYELGTLLGKGPDRGLQIAMPVFDPGSAVSLPDNV
CCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCC
PADLVSRRPDIVAARWQVEAAMHNVKEAKAEFFPDVNLAAAFGFDAFGWSKFLTSSSRQI
CHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCCEE
QFGPAIHLPIFDAGALRSQLKGRFADFDLDVANYNQTLIGALSDVATQISSIRSIDRQAG
EECCEEEECCCCHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DAQRALDASTKAYELAVIRYKAGLSPQLQVLTADQNRLAAEQTVTNLKMRRRDLQFALIK
HHHHHHHCCCCEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALGGGFDATQTGLVVPTDTPPASSAAAAPATHAAN
HHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]