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The map label for this gene is lgrC [H]

Identifier: 186476431

GI number: 186476431

Start: 1896470

End: 1898800

Strand: Direct

Name: lgrC [H]

Synonym: Bphy_1673

Alternate gene names: 186476431

Gene position: 1896470-1898800 (Clockwise)

Preceding gene: 186476430

Following gene: 186476432

Centisome position: 54.51

GC content: 65.21

Gene sequence:

>2331_bases
ATGAACGGGATCACCTTGAATCTCGTGCCCGACTACGAGATCGATGCCGGCTACGCGCTGTTCCCTGCGACCGCCTGCCA
GACACGGTTCTGGCATGAGCAGAAGGCGTCGCCGAAAGCTTCCGCGCTCAACAGCGCGTTCCGGCTGCAATTGTCGGGGC
CGCTGAAAGCCGCGAGCATCGAACAGGTGCTGTGCGAACTGGTCGCGCGACACGAGATATTGCGTACCGGCTTCCAGATG
ACGGGTGCGGGGCTGCGCCAGCAGGTCGCGAGCCGCGTCCCCTTCAAGCTCGACGTGGTCGACCTGACGGGCTTCGAGGA
AAAGGCCGCCCTTGCGGAGGCCGAGCGGGTCGGCCGGCTACAGGCCAGCACGCCGTTCGACTTGTCGTCCCCCTCCTTCT
TCCGGGCCGTGTGGCTGCCCAGGTCGCCCACGCAGGGTGAACTGCAGCTGACTTTCCATTCGCTTGTCATCGATGGCTGG
TCGTTCGCGATCCTCGTGTGCGAACTCGTGGAAGGGCTTGCCGCGTTGCATGCCGGCCATGATCCCCAATTCGCCGATGT
CGAGCTTCACCATGGTGACTACGCGCTCTGGAAGGAAGAGTTCGTTGCCAGCGGCGCGCTCGACCGCGCTCGCGCCCATT
GGCGCCAGGAACTTCGCGATTTCCGCCGCTTCGAGGTTCCGGGCGATCGCCCCCGGCCGCAGCAGCGGCGCTTCCAGGGC
GTGATTCGTTCCATCCTGTTGCCCGGCGCGCTCGGCGACCGCCTCAGCGCGGCGGCCAAGGCCCAGGGCGTCACGCTGTT
CAGCGTAGCGGCGGCTGGCCTCGCGATGGCGCTGCAAACGGCGACCGGCCAGAGCCGGGTTGCCATGGGCACCCAGATGT
CGGTGCGGGATCAGCAGGAGCTCGAGGGCGTGATCGGACCGCTCATCAACACGGTGATCCTGCGCCTCGACGTGCCTCAC
GGCAGCACCCTCGCCGCCGTTACCGCACAGTGTGGCGCCAAGCTCAGCGACGCCATCGAACACCTTCACCTGTCATTCGA
AGAAATGATAGAGCTGGCCGGCGAGGTTGCCGATCCGGATCGTCCGCCGCTATGCCCCGTCAATTTCGCCCTGCAGCAAA
GCTTCGTCGGCGTAGGCGATGAGGTTCGCCGTCAGGATTTCTCTGCGACGACCTCGCCCTCCTACAACGCGGGCGCGCTC
TACGATCTCAACTTCTTCATGGTTCGGCGTCCTGAAGGCTGGCGCATCTCCTGCGAAGGCGACACGGACCTCTACGACGT
CGAGACGATCGACGGGCATCTGGCAAAGTGGCGCGAGATGCTGGAAACCGTGGATAGCGAGGCGCAACGGCCGCTGGCGC
TCCCTGCCGGGGGCGAGGCGGCGAAATTCGTCACGGGTGTCGGCGCGAGCGGTTTCATGAGTCAGGCCGAGCTGGCGGCG
AAAGCGCGCAATATCGTGCGATACAACGAGAATGCGCCGGGCACGCCCGTCATCGCGCTCAACAATACGGGCGTGCTGTT
CGGACTGGCTCAGCAGATCGGCTCGGACCGGCCGCTGATCGACATCCCGATGGTGCCCGAAGGCCCGCCGCGCGAGTTCC
CGCCGCGCGCGTTCGAGGATATCGCCGCAGACGCGGTGCGGCTGATCAGGCTGGCCCAGCCCAAAGGTCCCTATATTCTC
ATGGGCCTGTGCGTGCTCGGCGCGCTGTCACTGGAGGCGGCCCATCAGCTTCGGCGCGAAGGCGAAAGCGTGGAACTCGT
TATCCTCAACGATTCCTGGTGCCCCGGCTATCGCGAGATGATGCCCTGGTACGATCGGGAGTTGCGCAAGATGCAAGTGC
GTGCGGACAACATTCCGCGCGACTTCCGCAAGGCCGTGCGGGGCGAGACTTCCATGGTCTCGTTCCTCAAGCAGTACCGG
ATCGTGCGCCGGCTCGGGATTGCAGACCTTGCGCTCAAGCTCGGGCTGATCAAGGACAAGGCTGCAGATCACACGATTGC
AGAGAACCGCTGGTACATGGAATATCTGCTGGCCCAGCAGGCCCGGTACCGTCCGGCGCCCTACGACGGCAACGTGCAGA
TTTTCCGCAGCGATCAGGTGCTGAAGGGACGCCTGTTCGCGTGGGATCTGGGATGGCAGCGCGTGCTGACGGGCAAACAG
GTCGTCACGCCGGTTCCGGGCATGCACGATCAGATGTTCCGCGCCGCCGGCGCTGCCGTGATCGGCAAGCAGGTGCGCGA
GCACCTCGCCGAAATCGAGGCTGACAGCAACAAGGCCAGCGCCGGCGAGCAGCACGCGCCGTTAGACTGCGCAAGCCGTG
CCGAAGCTTAG

Upstream 100 bases:

>100_bases
CCTCGACGGCACGCAGGAGAACGAGGTGAAGCAGGCGCCTGCCGTGTTGCGTCCCTCGATCCACAACTTCAAACGCAGAC
ATGCGGAGGGAGTCTGAGCG

Downstream 100 bases:

>100_bases
ATCGTTGGGCGAACTGCTTATGTCCCGTTTGCGTCGAGTCGTACTGGCCGTGTTTTGCGGCGCACTGACGGTAGCCGGCC
TCGTCTTTATCAAACTGGGC

Product: condensation domain-containing protein

Products: NA

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MNGITLNLVPDYEIDAGYALFPATACQTRFWHEQKASPKASALNSAFRLQLSGPLKAASIEQVLCELVARHEILRTGFQM
TGAGLRQQVASRVPFKLDVVDLTGFEEKAALAEAERVGRLQASTPFDLSSPSFFRAVWLPRSPTQGELQLTFHSLVIDGW
SFAILVCELVEGLAALHAGHDPQFADVELHHGDYALWKEEFVASGALDRARAHWRQELRDFRRFEVPGDRPRPQQRRFQG
VIRSILLPGALGDRLSAAAKAQGVTLFSVAAAGLAMALQTATGQSRVAMGTQMSVRDQQELEGVIGPLINTVILRLDVPH
GSTLAAVTAQCGAKLSDAIEHLHLSFEEMIELAGEVADPDRPPLCPVNFALQQSFVGVGDEVRRQDFSATTSPSYNAGAL
YDLNFFMVRRPEGWRISCEGDTDLYDVETIDGHLAKWREMLETVDSEAQRPLALPAGGEAAKFVTGVGASGFMSQAELAA
KARNIVRYNENAPGTPVIALNNTGVLFGLAQQIGSDRPLIDIPMVPEGPPREFPPRAFEDIAADAVRLIRLAQPKGPYIL
MGLCVLGALSLEAAHQLRREGESVELVILNDSWCPGYREMMPWYDRELRKMQVRADNIPRDFRKAVRGETSMVSFLKQYR
IVRRLGIADLALKLGLIKDKAADHTIAENRWYMEYLLAQQARYRPAPYDGNVQIFRSDQVLKGRLFAWDLGWQRVLTGKQ
VVTPVPGMHDQMFRAAGAAVIGKQVREHLAEIEADSNKASAGEQHAPLDCASRAEA

Sequences:

>Translated_776_residues
MNGITLNLVPDYEIDAGYALFPATACQTRFWHEQKASPKASALNSAFRLQLSGPLKAASIEQVLCELVARHEILRTGFQM
TGAGLRQQVASRVPFKLDVVDLTGFEEKAALAEAERVGRLQASTPFDLSSPSFFRAVWLPRSPTQGELQLTFHSLVIDGW
SFAILVCELVEGLAALHAGHDPQFADVELHHGDYALWKEEFVASGALDRARAHWRQELRDFRRFEVPGDRPRPQQRRFQG
VIRSILLPGALGDRLSAAAKAQGVTLFSVAAAGLAMALQTATGQSRVAMGTQMSVRDQQELEGVIGPLINTVILRLDVPH
GSTLAAVTAQCGAKLSDAIEHLHLSFEEMIELAGEVADPDRPPLCPVNFALQQSFVGVGDEVRRQDFSATTSPSYNAGAL
YDLNFFMVRRPEGWRISCEGDTDLYDVETIDGHLAKWREMLETVDSEAQRPLALPAGGEAAKFVTGVGASGFMSQAELAA
KARNIVRYNENAPGTPVIALNNTGVLFGLAQQIGSDRPLIDIPMVPEGPPREFPPRAFEDIAADAVRLIRLAQPKGPYIL
MGLCVLGALSLEAAHQLRREGESVELVILNDSWCPGYREMMPWYDRELRKMQVRADNIPRDFRKAVRGETSMVSFLKQYR
IVRRLGIADLALKLGLIKDKAADHTIAENRWYMEYLLAQQARYRPAPYDGNVQIFRSDQVLKGRLFAWDLGWQRVLTGKQ
VVTPVPGMHDQMFRAAGAAVIGKQVREHLAEIEADSNKASAGEQHAPLDCASRAEA
>Mature_776_residues
MNGITLNLVPDYEIDAGYALFPATACQTRFWHEQKASPKASALNSAFRLQLSGPLKAASIEQVLCELVARHEILRTGFQM
TGAGLRQQVASRVPFKLDVVDLTGFEEKAALAEAERVGRLQASTPFDLSSPSFFRAVWLPRSPTQGELQLTFHSLVIDGW
SFAILVCELVEGLAALHAGHDPQFADVELHHGDYALWKEEFVASGALDRARAHWRQELRDFRRFEVPGDRPRPQQRRFQG
VIRSILLPGALGDRLSAAAKAQGVTLFSVAAAGLAMALQTATGQSRVAMGTQMSVRDQQELEGVIGPLINTVILRLDVPH
GSTLAAVTAQCGAKLSDAIEHLHLSFEEMIELAGEVADPDRPPLCPVNFALQQSFVGVGDEVRRQDFSATTSPSYNAGAL
YDLNFFMVRRPEGWRISCEGDTDLYDVETIDGHLAKWREMLETVDSEAQRPLALPAGGEAAKFVTGVGASGFMSQAELAA
KARNIVRYNENAPGTPVIALNNTGVLFGLAQQIGSDRPLIDIPMVPEGPPREFPPRAFEDIAADAVRLIRLAQPKGPYIL
MGLCVLGALSLEAAHQLRREGESVELVILNDSWCPGYREMMPWYDRELRKMQVRADNIPRDFRKAVRGETSMVSFLKQYR
IVRRLGIADLALKLGLIKDKAADHTIAENRWYMEYLLAQQARYRPAPYDGNVQIFRSDQVLKGRLFAWDLGWQRVLTGKQ
VVTPVPGMHDQMFRAAGAAVIGKQVREHLAEIEADSNKASAGEQHAPLDCASRAEA

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 85499; Mature: 85499

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGITLNLVPDYEIDAGYALFPATACQTRFWHEQKASPKASALNSAFRLQLSGPLKAASI
CCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCHHHH
EQVLCELVARHEILRTGFQMTGAGLRQQVASRVPFKLDVVDLTGFEEKAALAEAERVGRL
HHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCC
QASTPFDLSSPSFFRAVWLPRSPTQGELQLTFHSLVIDGWSFAILVCELVEGLAALHAGH
CCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHCCC
DPQFADVELHHGDYALWKEEFVASGALDRARAHWRQELRDFRRFEVPGDRPRPQQRRFQG
CCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VIRSILLPGALGDRLSAAAKAQGVTLFSVAAAGLAMALQTATGQSRVAMGTQMSVRDQQE
HHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHH
LEGVIGPLINTVILRLDVPHGSTLAAVTAQCGAKLSDAIEHLHLSFEEMIELAGEVADPD
HHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCC
RPPLCPVNFALQQSFVGVGDEVRRQDFSATTSPSYNAGALYDLNFFMVRRPEGWRISCEG
CCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEECC
DTDLYDVETIDGHLAKWREMLETVDSEAQRPLALPAGGEAAKFVTGVGASGFMSQAELAA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHH
KARNIVRYNENAPGTPVIALNNTGVLFGLAQQIGSDRPLIDIPMVPEGPPREFPPRAFED
HHHHHEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHH
IAADAVRLIRLAQPKGPYILMGLCVLGALSLEAAHQLRREGESVELVILNDSWCPGYREM
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
MPWYDRELRKMQVRADNIPRDFRKAVRGETSMVSFLKQYRIVRRLGIADLALKLGLIKDK
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
AADHTIAENRWYMEYLLAQQARYRPAPYDGNVQIFRSDQVLKGRLFAWDLGWQRVLTGKQ
CCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCC
VVTPVPGMHDQMFRAAGAAVIGKQVREHLAEIEADSNKASAGEQHAPLDCASRAEA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNGITLNLVPDYEIDAGYALFPATACQTRFWHEQKASPKASALNSAFRLQLSGPLKAASI
CCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCHHHH
EQVLCELVARHEILRTGFQMTGAGLRQQVASRVPFKLDVVDLTGFEEKAALAEAERVGRL
HHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCC
QASTPFDLSSPSFFRAVWLPRSPTQGELQLTFHSLVIDGWSFAILVCELVEGLAALHAGH
CCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHCCC
DPQFADVELHHGDYALWKEEFVASGALDRARAHWRQELRDFRRFEVPGDRPRPQQRRFQG
CCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VIRSILLPGALGDRLSAAAKAQGVTLFSVAAAGLAMALQTATGQSRVAMGTQMSVRDQQE
HHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHH
LEGVIGPLINTVILRLDVPHGSTLAAVTAQCGAKLSDAIEHLHLSFEEMIELAGEVADPD
HHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCC
RPPLCPVNFALQQSFVGVGDEVRRQDFSATTSPSYNAGALYDLNFFMVRRPEGWRISCEG
CCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEECC
DTDLYDVETIDGHLAKWREMLETVDSEAQRPLALPAGGEAAKFVTGVGASGFMSQAELAA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHH
KARNIVRYNENAPGTPVIALNNTGVLFGLAQQIGSDRPLIDIPMVPEGPPREFPPRAFED
HHHHHEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHH
IAADAVRLIRLAQPKGPYILMGLCVLGALSLEAAHQLRREGESVELVILNDSWCPGYREM
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHH
MPWYDRELRKMQVRADNIPRDFRKAVRGETSMVSFLKQYRIVRRLGIADLALKLGLIKDK
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
AADHTIAENRWYMEYLLAQQARYRPAPYDGNVQIFRSDQVLKGRLFAWDLGWQRVLTGKQ
CCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCC
VVTPVPGMHDQMFRAAGAAVIGKQVREHLAEIEADSNKASAGEQHAPLDCASRAEA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA