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The map label for this gene is mtnN [H]

Identifier: 186476347

GI number: 186476347

Start: 1801660

End: 1802448

Strand: Reverse

Name: mtnN [H]

Synonym: Bphy_1589

Alternate gene names: 186476347

Gene position: 1802448-1801660 (Counterclockwise)

Preceding gene: 186476348

Following gene: 186476344

Centisome position: 51.81

GC content: 66.16

Gene sequence:

>789_bases
ATGAGCGCGCTACCTTCGGAAGCGACGATTCCGCGCCGTCCGCTTGGCGTGATGGCGGCGCTGCAGCAGGAACTCGGTGA
TCTGCTGATCGCGATGCGCGCCGAGGGCGCCGTCGAAACCATCACGCACGGCAAGCGCGACTATCACATTGGCACGGTGC
ACGGCGCGCCTTGTGTGGTGACGCTGGCGCGCGTCGGCAAGGTCGCGGCGGCCGCGACGGTGAGCGCGCTGATCCATGCG
TTCGATGTGGAAGCCGTCGTGTTCACGGGCGTCGCGGGCGGCGTCGGGCCGGCGGTGCGGATCGGCGATGTCGTCGTGGC
GGAAACGCTCATGCAGCATGACATGGATGCGTCGCCGCTCTTTCCTCGGTTCGAAGTGCCGCTGCTCGGTGTGTCGCGTT
TTGCCGCCGATGCACCGTTGACTGTCGCGCTGGCGGCTGCCTGCGAGCGTTTCATCGACGAAGAGGGCGATGCGCTGTCG
CAGCGTTTTGTGACGGAAGCGCGTCCCGTCGTGCATCGCGGTCTGATTTTGAGCGGCGATCAGTTCGTCGCGAGCGCGAC
AGCCGTCGATCTGCTGCGCGCCGCATTCCCGGACGCGCTTGCCGTCGAGATGGAGGGCGCGGCGATCGCGCAGGTCTGTT
ACGAGTACAACGTGCCGTGCGCGATCGTGCGGACCGTTTCGGACACGGCGGACGCGCATGCGCCCGCATCGTTCGTCACG
TTTCTGACCGAGATCGCGGGCACGTATTCGAGTGGAATACTGAAGCGGTTTTTGTCGGCGCGCGGATGA

Upstream 100 bases:

>100_bases
CGCTCGAAGGCGGTGGCGCGGATGCGAAGGCACAGGTCAAGTTCAAGCGGCACGGCGAGAAATGGCTCGCGCTGGCCGTC
GCCAAACTGCAGGCGGTCGA

Downstream 100 bases:

>100_bases
GCCGAAATTAAGTACCCCGCGCCGCGTTGGCGGCGACGCTCAGCCGCCGCGTGTGCCGAAACCGAGTGCCACGGCGTCAC
GAATCTGCTGCAAAGCGGAT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSALPSEATIPRRPLGVMAALQQELGDLLIAMRAEGAVETITHGKRDYHIGTVHGAPCVVTLARVGKVAAAATVSALIHA
FDVEAVVFTGVAGGVGPAVRIGDVVVAETLMQHDMDASPLFPRFEVPLLGVSRFAADAPLTVALAAACERFIDEEGDALS
QRFVTEARPVVHRGLILSGDQFVASATAVDLLRAAFPDALAVEMEGAAIAQVCYEYNVPCAIVRTVSDTADAHAPASFVT
FLTEIAGTYSSGILKRFLSARG

Sequences:

>Translated_262_residues
MSALPSEATIPRRPLGVMAALQQELGDLLIAMRAEGAVETITHGKRDYHIGTVHGAPCVVTLARVGKVAAAATVSALIHA
FDVEAVVFTGVAGGVGPAVRIGDVVVAETLMQHDMDASPLFPRFEVPLLGVSRFAADAPLTVALAAACERFIDEEGDALS
QRFVTEARPVVHRGLILSGDQFVASATAVDLLRAAFPDALAVEMEGAAIAQVCYEYNVPCAIVRTVSDTADAHAPASFVT
FLTEIAGTYSSGILKRFLSARG
>Mature_261_residues
SALPSEATIPRRPLGVMAALQQELGDLLIAMRAEGAVETITHGKRDYHIGTVHGAPCVVTLARVGKVAAAATVSALIHAF
DVEAVVFTGVAGGVGPAVRIGDVVVAETLMQHDMDASPLFPRFEVPLLGVSRFAADAPLTVALAAACERFIDEEGDALSQ
RFVTEARPVVHRGLILSGDQFVASATAVDLLRAAFPDALAVEMEGAAIAQVCYEYNVPCAIVRTVSDTADAHAPASFVTF
LTEIAGTYSSGILKRFLSARG

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=30.8695652173913, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27368; Mature: 27237

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALPSEATIPRRPLGVMAALQQELGDLLIAMRAEGAVETITHGKRDYHIGTVHGAPCVV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCHHHH
TLARVGKVAAAATVSALIHAFDVEAVVFTGVAGGVGPAVRIGDVVVAETLMQHDMDASPL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
FPRFEVPLLGVSRFAADAPLTVALAAACERFIDEEGDALSQRFVTEARPVVHRGLILSGD
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEECCC
QFVASATAVDLLRAAFPDALAVEMEGAAIAQVCYEYNVPCAIVRTVSDTADAHAPASFVT
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHH
FLTEIAGTYSSGILKRFLSARG
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALPSEATIPRRPLGVMAALQQELGDLLIAMRAEGAVETITHGKRDYHIGTVHGAPCVV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCHHHH
TLARVGKVAAAATVSALIHAFDVEAVVFTGVAGGVGPAVRIGDVVVAETLMQHDMDASPL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
FPRFEVPLLGVSRFAADAPLTVALAAACERFIDEEGDALSQRFVTEARPVVHRGLILSGD
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEECCC
QFVASATAVDLLRAAFPDALAVEMEGAAIAQVCYEYNVPCAIVRTVSDTADAHAPASFVT
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHH
FLTEIAGTYSSGILKRFLSARG
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]