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The map label for this gene is boxC [H]

Identifier: 186476298

GI number: 186476298

Start: 1740250

End: 1741932

Strand: Reverse

Name: boxC [H]

Synonym: Bphy_1540

Alternate gene names: 186476298

Gene position: 1741932-1740250 (Counterclockwise)

Preceding gene: 186476299

Following gene: 186476297

Centisome position: 50.07

GC content: 63.4

Gene sequence:

>1683_bases
ATGTCCGCAGTCATGTCCCCGGCACACGCCGCCGCCGCGCGCGTCGACTACCGCACGGATCCCGCGCACTACAAGCACTG
GAAGCTCTCGTTCGACGGCGCCGTTGCGACGCTCGGCATCGATATCGCCGAAGACGGCGGCATCCGTGACGGCTACAAGC
TGAAGCTCAATTCATACGACCTCGGCGTCGACATCGAACTTCACGATGCACTTCAGCGCATCCGCTTCGAGCATCCCGAA
GTGCGCACGGTCGTCGTCACGAGTCTGAAGGATCGTGTGTTCTGCTCGGGTGCAAACATCTTCATGCTGGGTCTGTCGTC
GCATGCATGGAAGGTCAACTTCTGCAAATTCACGAACGAGACTCGCAACGGCATCGAGGACTCGTCGCTTCACTCGGGCC
TGAAGTTTCTTGCAGCCGTAAATGGTTCATGTGCAGGCGGCGGATATGAACTGGCGCTCGCCTGCGACGAAATCTATCTG
GTCGACGACCGCTCGTCGTCGGTGGCGCTGCCGGAAGTGCCGCTACTCGGTGTGCTGCCTGGCACGGGCGGCCTCACGCG
CGTCACGGACAAGCGCAAGGTGCGGCACGATCGCGCCGACATATTCTGCACGGTGGTCGAAGGCATTCGCGGCACGCGTG
CGAAAGAATGGCGTCTTGTCGATGAAGTCGTAAAGCCGAACGGGTTCGAACAGGCGATCGCTGCGCGCGCGCTGGAACTC
GCTGCGCTAAGCGACCGACCGGCGAATGCACGAGGCGTGACGCTGACGCGCATTGAACGCATGGATCGCGAAGACGGCAT
CACGTATGCGACGCTCGACGTGACGATCGACCGCGCGAAGCGCACGGCCACGTTCACGGCCAAAGCGCCGTCGACGGCGC
AACCTTTGGATATCGATGCCGTCGTCGCGATGGGCGCGAGCTGGTGGCCGCTGCAATTTGCGCGCGAACTCGACGACGCG
ATCCTGTCGATGCGCACCAACGAACTCGATGTCGGCACGTGGATTCTAAAGACGCAAGGCGACGCGCGTGGCGTGCTCGC
CGCCGACGCCACGCTGCTGCAGCACAAGGACCACTGGTTCGTGCGCGAAACGATCGGTCTGCTGCGCCGCACGCTCGCGC
GCATCGACGTCTCGTCGCGTTCGCTGTTTGCCCTGATCGAGCCGGGCTCGTGTTTCGCGGGTACGCTCGCCGAGTTCGCG
TTTGCCGCCGACCGCACTTACATGGCCGCGCTGCCCGCGAACGAAGATGAAGAGCCCGCGATCACGCTGTCGGAGGTCAA
TTTCGGTCTCTATCCGATGGTCACGCATCAGTCGCGGCTTGCGCGGCGCTTCTACGAAGAGACGGAGCCACTCGACGCCG
CGCGCGCGAAAACCGGCCAGCCAGTGAAAGCGGCGGAAGCGGAGCGGCTCGGCCTCGTGACGGCGTCGCTGGACGATATC
GATTGGGCCGATGAGATTCGCATCGCCCTCGAGGAACGCGCGGCGATGTCGCCGGATGCGCTGACGGGCATGGAAGCGAA
TTTGCGTTTCAATGGCCGCGAGACGATGGAGACGCGTATCTTCGGGCGGCTGACGGCCTGGCAGAACTGGATTTTCAACC
GGCCGAATGCGGTGGGCGAGAAGGGCGCGCTCAAGGTGTACGGCAAGGGCAGCAAGGCGCAATTCGACGTCTCGCGTGTC
TGA

Upstream 100 bases:

>100_bases
ATAGGGGATAACCCCGCAACATGAAGTAAAGTGCTTTACATGGGTGGATGGATGCATTATTGTTCGCTAAAACAAACTGC
ATCGTTCCAGGAGACGCCTC

Downstream 100 bases:

>100_bases
CCCACGCACGCGCATCTACATCGTGAACCTGCATCGCGCTCAAGGAACCGACATGTCCACCATCGACTACAGCGACAAGA
TTCCGAACAACGTCAACCTC

Product: benzoyl-CoA-dihydrodiol lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSAVMSPAHAAAARVDYRTDPAHYKHWKLSFDGAVATLGIDIAEDGGIRDGYKLKLNSYDLGVDIELHDALQRIRFEHPE
VRTVVVTSLKDRVFCSGANIFMLGLSSHAWKVNFCKFTNETRNGIEDSSLHSGLKFLAAVNGSCAGGGYELALACDEIYL
VDDRSSSVALPEVPLLGVLPGTGGLTRVTDKRKVRHDRADIFCTVVEGIRGTRAKEWRLVDEVVKPNGFEQAIAARALEL
AALSDRPANARGVTLTRIERMDREDGITYATLDVTIDRAKRTATFTAKAPSTAQPLDIDAVVAMGASWWPLQFARELDDA
ILSMRTNELDVGTWILKTQGDARGVLAADATLLQHKDHWFVRETIGLLRRTLARIDVSSRSLFALIEPGSCFAGTLAEFA
FAADRTYMAALPANEDEEPAITLSEVNFGLYPMVTHQSRLARRFYEETEPLDAARAKTGQPVKAAEAERLGLVTASLDDI
DWADEIRIALEERAAMSPDALTGMEANLRFNGRETMETRIFGRLTAWQNWIFNRPNAVGEKGALKVYGKGSKAQFDVSRV

Sequences:

>Translated_560_residues
MSAVMSPAHAAAARVDYRTDPAHYKHWKLSFDGAVATLGIDIAEDGGIRDGYKLKLNSYDLGVDIELHDALQRIRFEHPE
VRTVVVTSLKDRVFCSGANIFMLGLSSHAWKVNFCKFTNETRNGIEDSSLHSGLKFLAAVNGSCAGGGYELALACDEIYL
VDDRSSSVALPEVPLLGVLPGTGGLTRVTDKRKVRHDRADIFCTVVEGIRGTRAKEWRLVDEVVKPNGFEQAIAARALEL
AALSDRPANARGVTLTRIERMDREDGITYATLDVTIDRAKRTATFTAKAPSTAQPLDIDAVVAMGASWWPLQFARELDDA
ILSMRTNELDVGTWILKTQGDARGVLAADATLLQHKDHWFVRETIGLLRRTLARIDVSSRSLFALIEPGSCFAGTLAEFA
FAADRTYMAALPANEDEEPAITLSEVNFGLYPMVTHQSRLARRFYEETEPLDAARAKTGQPVKAAEAERLGLVTASLDDI
DWADEIRIALEERAAMSPDALTGMEANLRFNGRETMETRIFGRLTAWQNWIFNRPNAVGEKGALKVYGKGSKAQFDVSRV
>Mature_559_residues
SAVMSPAHAAAARVDYRTDPAHYKHWKLSFDGAVATLGIDIAEDGGIRDGYKLKLNSYDLGVDIELHDALQRIRFEHPEV
RTVVVTSLKDRVFCSGANIFMLGLSSHAWKVNFCKFTNETRNGIEDSSLHSGLKFLAAVNGSCAGGGYELALACDEIYLV
DDRSSSVALPEVPLLGVLPGTGGLTRVTDKRKVRHDRADIFCTVVEGIRGTRAKEWRLVDEVVKPNGFEQAIAARALELA
ALSDRPANARGVTLTRIERMDREDGITYATLDVTIDRAKRTATFTAKAPSTAQPLDIDAVVAMGASWWPLQFARELDDAI
LSMRTNELDVGTWILKTQGDARGVLAADATLLQHKDHWFVRETIGLLRRTLARIDVSSRSLFALIEPGSCFAGTLAEFAF
AADRTYMAALPANEDEEPAITLSEVNFGLYPMVTHQSRLARRFYEETEPLDAARAKTGQPVKAAEAERLGLVTASLDDID
WADEIRIALEERAAMSPDALTGMEANLRFNGRETMETRIFGRLTAWQNWIFNRPNAVGEKGALKVYGKGSKAQFDVSRV

Specific function: Catalyzes the ring opening of 2,3-dihydro-2,3- dihydroxybenzoyl-CoA to form 3,4-dehydroadipyl-CoA semialdehyde [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the benzoyl-CoA oxygenase component C family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=33.7016574585635, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=32.3383084577114, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653139, Length=242, Percent_Identity=29.7520661157025, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017633
- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.2.44 [H]

Molecular weight: Translated: 61607; Mature: 61475

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVMSPAHAAAARVDYRTDPAHYKHWKLSFDGAVATLGIDIAEDGGIRDGYKLKLNSYD
CCCCCCCHHHHHHEECCCCCCCCCEEEEEEECCEEEEEEEEEECCCCCCCCEEEEEECEE
LGVDIELHDALQRIRFEHPEVRTVVVTSLKDRVFCSGANIFMLGLSSHAWKVNFCKFTNE
CEEEEEHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEEEEECCCCCEEEEEEEECCH
TRNGIEDSSLHSGLKFLAAVNGSCAGGGYELALACDEIYLVDDRSSSVALPEVPLLGVLP
HHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCEECCCCCEEEEEC
GTGGLTRVTDKRKVRHDRADIFCTVVEGIRGTRAKEWRLVDEVVKPNGFEQAIAARALEL
CCCCCEECCHHHHHHHHHHHEEEEEHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
AALSDRPANARGVTLTRIERMDREDGITYATLDVTIDRAKRTATFTAKAPSTAQPLDIDA
HHCCCCCCCCCCEEEHHHHHCCHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCHH
VVAMGASWWPLQFARELDDAILSMRTNELDVGTWILKTQGDARGVLAADATLLQHKDHWF
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECHHHHHCCCCCH
VRETIGLLRRTLARIDVSSRSLFALIEPGSCFAGTLAEFAFAADRTYMAALPANEDEEPA
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCE
ITLSEVNFGLYPMVTHQSRLARRFYEETEPLDAARAKTGQPVKAAEAERLGLVTASLDDI
EEEEECCCCCEEEEECHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHEEEEEECCCCC
DWADEIRIALEERAAMSPDALTGMEANLRFNGRETMETRIFGRLTAWQNWIFNRPNAVGE
CCHHHHHHHHHHHCCCCCCHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGALKVYGKGSKAQFDVSRV
CCCEEEEECCCCCEEEECCC
>Mature Secondary Structure 
SAVMSPAHAAAARVDYRTDPAHYKHWKLSFDGAVATLGIDIAEDGGIRDGYKLKLNSYD
CCCCCCHHHHHHEECCCCCCCCCEEEEEEECCEEEEEEEEEECCCCCCCCEEEEEECEE
LGVDIELHDALQRIRFEHPEVRTVVVTSLKDRVFCSGANIFMLGLSSHAWKVNFCKFTNE
CEEEEEHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEEEEECCCCCEEEEEEEECCH
TRNGIEDSSLHSGLKFLAAVNGSCAGGGYELALACDEIYLVDDRSSSVALPEVPLLGVLP
HHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEEECCCCCEECCCCCEEEEEC
GTGGLTRVTDKRKVRHDRADIFCTVVEGIRGTRAKEWRLVDEVVKPNGFEQAIAARALEL
CCCCCEECCHHHHHHHHHHHEEEEEHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
AALSDRPANARGVTLTRIERMDREDGITYATLDVTIDRAKRTATFTAKAPSTAQPLDIDA
HHCCCCCCCCCCEEEHHHHHCCHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCHH
VVAMGASWWPLQFARELDDAILSMRTNELDVGTWILKTQGDARGVLAADATLLQHKDHWF
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECHHHHHCCCCCH
VRETIGLLRRTLARIDVSSRSLFALIEPGSCFAGTLAEFAFAADRTYMAALPANEDEEPA
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCE
ITLSEVNFGLYPMVTHQSRLARRFYEETEPLDAARAKTGQPVKAAEAERLGLVTASLDDI
EEEEECCCCCEEEEECHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHEEEEEECCCCC
DWADEIRIALEERAAMSPDALTGMEANLRFNGRETMETRIFGRLTAWQNWIFNRPNAVGE
CCHHHHHHHHHHHCCCCCCHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
KGALKVYGKGSKAQFDVSRV
CCCEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12399500 [H]