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The map label for this gene is yadA [H]

Identifier: 186476284

GI number: 186476284

Start: 1722943

End: 1725150

Strand: Reverse

Name: yadA [H]

Synonym: Bphy_1526

Alternate gene names: 186476284

Gene position: 1725150-1722943 (Counterclockwise)

Preceding gene: 186476285

Following gene: 186476281

Centisome position: 49.58

GC content: 65.62

Gene sequence:

>2208_bases
ATGAGCAATTTGCAGAGCGGACTGGCGGTCAAGCGTGGGCGGACGTTTTCGTCATATGGTCGCCGTGACGGGCGGCCAAT
GCATAATGGGTGCGTCGGCATGGCCGTCGCCGTCAGTCTTGGGGCAATAGCATGGTCGCCGGCCGCACTCGCGGCTTCCG
TCACCGACTACATTGCAGTGAGCACTAACGTCATGGCGGGTACGCCGACACAGGTTTCGAACGACCTCAACGCGATGGCC
ATCGGCCCGTCTGCGAACGCGTCGGGCAGCAATGCGCTCTCAGTCGGGGCGGGTGCTGCCGCGAGCCGCATGGGATCGAC
GGCGGTGGGCTCGCGTACCGCGGCATTGGGCATCAATTCGACGGTGATCGGTTACAGCGCGTCGACGGGTTTCAATGCGG
ACCGGGCGGTGTCGATTGGTTACATGGCGTCTGCTGACGGAGCGGATTCGCTCGCGTTCGGCTCGATGTCGATGGCGGGC
GGCCAACGTTCCCTCGCGATCGGGGTCAACGCATTCACGAGCACGGCCGGCGCGGACGGACTGGCGCTCGGGTCCGGCAG
CCAGGTGGTCGCGAATGGCGCCGTCGCATTGGGCGCGGGCGCGAAGGCTGACCGCGCGAACACGGTGTCGGTGGGCAATG
CGACGCAGCAGCGCCAGATCGTCAATGTTGCAGCGGGAACGGCCGATACGGACGCCGTCAACGTCAGCCAGTTGCGCGGT
GCCGTGTCTTCCGGGCTGGCGGACGCGGTGATGTACGACTCGTCGGCGCATGACAGCGTGACGCTGGGCGGTGCGACAGC
GGGCGCGGCTGTACACCTCGGCAACGTGGCCAATGGCGCCGTCGATGCTGCCAGCCACGACGCGATCAACGGCAGTCAAC
TGCATGGCCTCAGCACGAGCGTGGCTTCGGCGCTCGGTGGCGGTGCATCGGTCGCGGCGGACGGCACGGTCGTCGCACCG
AGCTATCGGGTGGGCGGCAGTGTGTTTCGCAATGTCGGCGACGCGCTCGGTAATCTCGACGGCCGGGTCGCGAGCAACAC
CAGCGCGATCAACGACCTGAACGTCGCGCTCGGCAATGTGATCAGCAACGGCATTGAGCCGCGCTTCTTCCGTGCCAATT
CAACGCTTGCCGATTCGCTTGCGACGGGCGCGGATTCCGTTGCGATCGGCGGCGGCGCGCAAGCTGCGTTTTCGAATTCG
GTCGCGCTCGGCGCCAACGCGGTGGCCGATCGGGCCAATGCAGTATCGGTCGGCTCGGCGGGGAGCGAGCGGCAGATCAC
GCATGTTGCCGCGGGCACGGCCGACACCGACGCCGTCAACGTTGCGCAGTTGAAGCAGTCTGGACTGATCGACGGCAATG
GTCAGGTAGCGAGCGCAGTGGTGTATGACAGCGCGAGCGGACAGGTTGATTACACGAGCGTGACGTTAGGACACGGCGTC
GCGGGCGGCACGGCGATCCACAATCTTGCTGATGGCGTACTGGCGAGCGACGCAGTCAACCTCGGGCAGTTGACGGATGC
GATCAATCAGGTCACTAACGCGCAGGTTCCGGGTGTGCCTACGCCATTCGTAAGCGCGAACGGGGACGCGACGGCGGAAG
CGGCGTCTGCAACGGGCACGCACGCGACCGCAGTTGGGCCGGCCGCGGTCGCACACGGCGATCAGGCGACGGCGCTCGGC
GGCGGTGCGCAGGCCAGCGCTACGGCAGCGACCGCCATCGGCTCGCTGGCTGCCGCGAACGGCGCCAACACGACGGCATT
AGGCGCGGGCAGCCAGGCGCTTGCCAATGGCGCAGTCGCATTAGGTGCAGGCTCGGTCGCAGACCGTGCGAATACAGTAT
CGGTCGGTCAGGCAGGCAGCGAGCGGCAGATCGTTAACGTTGCGCCGGGTACACATGGCACGGATGCCGTCAACCTGAAC
CAGTTGAACGCCGCCGTCGATCAGACCTATCAGTCGATTCATGATCTGGACAGAAGCACGCGCAAGGGCATCGCGTCCGC
TTCGGCTTTGCAGATCGTTACGCCCTATTTGCCGGGACGTACGACACTCAATGCCGGTGTCGCCGGTTACCGCGGGCAGG
CGGCATTCGGGTTGGGCGTATCGCGCTGGAATGAGAAGGGGACGATCAATCTCAATGCGGGCGTAGCGTCGTCTGGCAGC
AACAGCACGGTTGTGCGTGCAGGGATCGGTATCGTGCTTGGCAACTGA

Upstream 100 bases:

>100_bases
ATACCGCGTCCAATATGATTCGGTATACGAAGCAATGGCTCTCTAAGCCGGGCGGTGCCGCGTTTTGGGGAGAGCAGTGG
TTTTCGTATCAAGGTTTTCG

Downstream 100 bases:

>100_bases
TCACGGCTGGAAAGCTGGCGTGGTGTCTCGGGATAGCACGCCAGCGTTCGTAGGAAGACCGATCGGAAGCGCGTGTTAAT
TTCCGTGCATGCTCAAAACG

Product: YadA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MSNLQSGLAVKRGRTFSSYGRRDGRPMHNGCVGMAVAVSLGAIAWSPAALAASVTDYIAVSTNVMAGTPTQVSNDLNAMA
IGPSANASGSNALSVGAGAAASRMGSTAVGSRTAALGINSTVIGYSASTGFNADRAVSIGYMASADGADSLAFGSMSMAG
GQRSLAIGVNAFTSTAGADGLALGSGSQVVANGAVALGAGAKADRANTVSVGNATQQRQIVNVAAGTADTDAVNVSQLRG
AVSSGLADAVMYDSSAHDSVTLGGATAGAAVHLGNVANGAVDAASHDAINGSQLHGLSTSVASALGGGASVAADGTVVAP
SYRVGGSVFRNVGDALGNLDGRVASNTSAINDLNVALGNVISNGIEPRFFRANSTLADSLATGADSVAIGGGAQAAFSNS
VALGANAVADRANAVSVGSAGSERQITHVAAGTADTDAVNVAQLKQSGLIDGNGQVASAVVYDSASGQVDYTSVTLGHGV
AGGTAIHNLADGVLASDAVNLGQLTDAINQVTNAQVPGVPTPFVSANGDATAEAASATGTHATAVGPAAVAHGDQATALG
GGAQASATAATAIGSLAAANGANTTALGAGSQALANGAVALGAGSVADRANTVSVGQAGSERQIVNVAPGTHGTDAVNLN
QLNAAVDQTYQSIHDLDRSTRKGIASASALQIVTPYLPGRTTLNAGVAGYRGQAAFGLGVSRWNEKGTINLNAGVASSGS
NSTVVRAGIGIVLGN

Sequences:

>Translated_735_residues
MSNLQSGLAVKRGRTFSSYGRRDGRPMHNGCVGMAVAVSLGAIAWSPAALAASVTDYIAVSTNVMAGTPTQVSNDLNAMA
IGPSANASGSNALSVGAGAAASRMGSTAVGSRTAALGINSTVIGYSASTGFNADRAVSIGYMASADGADSLAFGSMSMAG
GQRSLAIGVNAFTSTAGADGLALGSGSQVVANGAVALGAGAKADRANTVSVGNATQQRQIVNVAAGTADTDAVNVSQLRG
AVSSGLADAVMYDSSAHDSVTLGGATAGAAVHLGNVANGAVDAASHDAINGSQLHGLSTSVASALGGGASVAADGTVVAP
SYRVGGSVFRNVGDALGNLDGRVASNTSAINDLNVALGNVISNGIEPRFFRANSTLADSLATGADSVAIGGGAQAAFSNS
VALGANAVADRANAVSVGSAGSERQITHVAAGTADTDAVNVAQLKQSGLIDGNGQVASAVVYDSASGQVDYTSVTLGHGV
AGGTAIHNLADGVLASDAVNLGQLTDAINQVTNAQVPGVPTPFVSANGDATAEAASATGTHATAVGPAAVAHGDQATALG
GGAQASATAATAIGSLAAANGANTTALGAGSQALANGAVALGAGSVADRANTVSVGQAGSERQIVNVAPGTHGTDAVNLN
QLNAAVDQTYQSIHDLDRSTRKGIASASALQIVTPYLPGRTTLNAGVAGYRGQAAFGLGVSRWNEKGTINLNAGVASSGS
NSTVVRAGIGIVLGN
>Mature_734_residues
SNLQSGLAVKRGRTFSSYGRRDGRPMHNGCVGMAVAVSLGAIAWSPAALAASVTDYIAVSTNVMAGTPTQVSNDLNAMAI
GPSANASGSNALSVGAGAAASRMGSTAVGSRTAALGINSTVIGYSASTGFNADRAVSIGYMASADGADSLAFGSMSMAGG
QRSLAIGVNAFTSTAGADGLALGSGSQVVANGAVALGAGAKADRANTVSVGNATQQRQIVNVAAGTADTDAVNVSQLRGA
VSSGLADAVMYDSSAHDSVTLGGATAGAAVHLGNVANGAVDAASHDAINGSQLHGLSTSVASALGGGASVAADGTVVAPS
YRVGGSVFRNVGDALGNLDGRVASNTSAINDLNVALGNVISNGIEPRFFRANSTLADSLATGADSVAIGGGAQAAFSNSV
ALGANAVADRANAVSVGSAGSERQITHVAAGTADTDAVNVAQLKQSGLIDGNGQVASAVVYDSASGQVDYTSVTLGHGVA
GGTAIHNLADGVLASDAVNLGQLTDAINQVTNAQVPGVPTPFVSANGDATAEAASATGTHATAVGPAAVAHGDQATALGG
GAQASATAATAIGSLAAANGANTTALGAGSQALANGAVALGAGSVADRANTVSVGQAGSERQIVNVAPGTHGTDAVNLNQ
LNAAVDQTYQSIHDLDRSTRKGIASASALQIVTPYLPGRTTLNAGVAGYRGQAAFGLGVSRWNEKGTINLNAGVASSGSN
STVVRAGIGIVLGN

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 70717; Mature: 70586

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLQSGLAVKRGRTFSSYGRRDGRPMHNGCVGMAVAVSLGAIAWSPAALAASVTDYIAV
CCCCHHCCEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEE
STNVMAGTPTQVSNDLNAMAIGPSANASGSNALSVGAGAAASRMGSTAVGSRTAALGINS
ECCEECCCCHHHCCCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCCCCCCCEEEEECCC
TVIGYSASTGFNADRAVSIGYMASADGADSLAFGSMSMAGGQRSLAIGVNAFTSTAGADG
EEEEEECCCCCCCCCEEEEEEEECCCCCCCEEECCEECCCCCEEEEEEEEHHCCCCCCCC
LALGSGSQVVANGAVALGAGAKADRANTVSVGNATQQRQIVNVAAGTADTDAVNVSQLRG
EEECCCCEEEECCCEEECCCCCCCCCCEEEECCCHHHHEEEEEECCCCCCCCCCHHHHHH
AVSSGLADAVMYDSSAHDSVTLGGATAGAAVHLGNVANGAVDAASHDAINGSQLHGLSTS
HHHHCCHHHHEECCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
VASALGGGASVAADGTVVAPSYRVGGSVFRNVGDALGNLDGRVASNTSAINDLNVALGNV
HHHHHCCCCEECCCCEEECCCHHCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHH
ISNGIEPRFFRANSTLADSLATGADSVAIGGGAQAAFSNSVALGANAVADRANAVSVGSA
HHCCCCCEEEECCCHHHHHHHCCCCCEEECCCCHHHHCCCEEECCHHHHCCCCEEEECCC
GSERQITHVAAGTADTDAVNVAQLKQSGLIDGNGQVASAVVYDSASGQVDYTSVTLGHGV
CCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEEEECCCC
AGGTAIHNLADGVLASDAVNLGQLTDAINQVTNAQVPGVPTPFVSANGDATAEAASATGT
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHCCCCC
HATAVGPAAVAHGDQATALGGGAQASATAATAIGSLAAANGANTTALGAGSQALANGAVA
CCCCCCCHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCEE
LGAGSVADRANTVSVGQAGSERQIVNVAPGTHGTDAVNLNQLNAAVDQTYQSIHDLDRST
ECCCCHHCCCCEEEECCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
RKGIASASALQIVTPYLPGRTTLNAGVAGYRGQAAFGLGVSRWNEKGTINLNAGVASSGS
HHCCCCCCEEEEEECCCCCCCEECCCCCCCCCCEEEECCHHHCCCCCEEEEECCCCCCCC
NSTVVRAGIGIVLGN
CCEEEEECEEEEECC
>Mature Secondary Structure 
SNLQSGLAVKRGRTFSSYGRRDGRPMHNGCVGMAVAVSLGAIAWSPAALAASVTDYIAV
CCCHHCCEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEE
STNVMAGTPTQVSNDLNAMAIGPSANASGSNALSVGAGAAASRMGSTAVGSRTAALGINS
ECCEECCCCHHHCCCCCEEEECCCCCCCCCCEEEECCCHHHHHCCCCCCCCCEEEEECCC
TVIGYSASTGFNADRAVSIGYMASADGADSLAFGSMSMAGGQRSLAIGVNAFTSTAGADG
EEEEEECCCCCCCCCEEEEEEEECCCCCCCEEECCEECCCCCEEEEEEEEHHCCCCCCCC
LALGSGSQVVANGAVALGAGAKADRANTVSVGNATQQRQIVNVAAGTADTDAVNVSQLRG
EEECCCCEEEECCCEEECCCCCCCCCCEEEECCCHHHHEEEEEECCCCCCCCCCHHHHHH
AVSSGLADAVMYDSSAHDSVTLGGATAGAAVHLGNVANGAVDAASHDAINGSQLHGLSTS
HHHHCCHHHHEECCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
VASALGGGASVAADGTVVAPSYRVGGSVFRNVGDALGNLDGRVASNTSAINDLNVALGNV
HHHHHCCCCEECCCCEEECCCHHCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHH
ISNGIEPRFFRANSTLADSLATGADSVAIGGGAQAAFSNSVALGANAVADRANAVSVGSA
HHCCCCCEEEECCCHHHHHHHCCCCCEEECCCCHHHHCCCEEECCHHHHCCCCEEEECCC
GSERQITHVAAGTADTDAVNVAQLKQSGLIDGNGQVASAVVYDSASGQVDYTSVTLGHGV
CCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEEEECCCC
AGGTAIHNLADGVLASDAVNLGQLTDAINQVTNAQVPGVPTPFVSANGDATAEAASATGT
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHCCCCC
HATAVGPAAVAHGDQATALGGGAQASATAATAIGSLAAANGANTTALGAGSQALANGAVA
CCCCCCCHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCEE
LGAGSVADRANTVSVGQAGSERQIVNVAPGTHGTDAVNLNQLNAAVDQTYQSIHDLDRST
ECCCCHHCCCCEEEECCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
RKGIASASALQIVTPYLPGRTTLNAGVAGYRGQAAFGLGVSRWNEKGTINLNAGVASSGS
HHCCCCCCEEEEEECCCCCCCEECCCCCCCCCCEEEECCHHHCCCCCEEEEECCCCCCCC
NSTVVRAGIGIVLGN
CCEEEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]