Click here to switch to the map view.

The map label for this gene is iscR [H]

Identifier: 186476217

GI number: 186476217

Start: 1641125

End: 1641649

Strand: Reverse

Name: iscR [H]

Synonym: Bphy_1459

Alternate gene names: 186476217

Gene position: 1641649-1641125 (Counterclockwise)

Preceding gene: 186476218

Following gene: 186476216

Centisome position: 47.18

GC content: 65.9

Gene sequence:

>525_bases
ATGAGACTCACCACGAAAGGCCGTTTCGCCGTCACGGCGATGATCGACCTGGCACTGCGCCAGGAGCAGGGCCCGGTGAC
GCTTGCGGGTATCAGCCAGCGCCAACACATCTCCTTGTCCTACCTCGAGCAGCTGTTCGGCAAGCTGCGCCGGCACGAGA
TCGTCGAATCCGTGCGCGGGCCGGGCGGCGGCTACAACCTCGCGCGCCGCGCGGAGGACGTGACCGTGGCGGACATCATC
ATCGCTGTCGACGAACCGCTCGATGCCACCCAGTGCGGCGGCAAGGGTTCGTGCGAAGGCACGAAGCATCACGACGGCCA
CTGCATGACGCATGAGCTTTGGTCGACGCTGAACCAGAAGATGGTCGAATATCTCGACTCCGTTTCCCTGAAAGACCTGG
TCGACCAGCAGCGCTCGCGCGAAGGCGCGACGGCCGTGCTGCGCGACCGGCGCACCGAAGCGCCCGCCGTCGAGCCGCGC
GCGGTGCCGAAAGGGCCGAATTCCGTTTTCAACATGGCCGGCTGA

Upstream 100 bases:

>100_bases
CGTTAAGTAAATGACCCAAATCGAGATAGGGATACTTGACTAAATCCGTCATGTATTTATACTTGACCAAACTTGTCGAG
AATTGCGGTTCCCACCACAT

Downstream 100 bases:

>100_bases
AAGAGCGCGCAAGAGACGCGAACGCCAGAACCGAGAAGCCATTAGCACTGATGTCCCCCGGAGCGATTGATGAATAACGA
CATTCCCCACCTGCCCATTT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQHISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAEDVTVADII
IAVDEPLDATQCGGKGSCEGTKHHDGHCMTHELWSTLNQKMVEYLDSVSLKDLVDQQRSREGATAVLRDRRTEAPAVEPR
AVPKGPNSVFNMAG

Sequences:

>Translated_174_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQHISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAEDVTVADII
IAVDEPLDATQCGGKGSCEGTKHHDGHCMTHELWSTLNQKMVEYLDSVSLKDLVDQQRSREGATAVLRDRRTEAPAVEPR
AVPKGPNSVFNMAG
>Mature_174_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQHISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAEDVTVADII
IAVDEPLDATQCGGKGSCEGTKHHDGHCMTHELWSTLNQKMVEYLDSVSLKDLVDQQRSREGATAVLRDRRTEAPAVEPR
AVPKGPNSVFNMAG

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=137, Percent_Identity=51.0948905109489, Blast_Score=140, Evalue=4e-35,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19106; Mature: 19106

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQHISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAEDVTVADIIIAVDEPLDATQCGGKGSCEGTKHHDGHCMTHELWSTLNQK
CCCCCHHHHHCCCCEEEHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
MVEYLDSVSLKDLVDQQRSREGATAVLRDRRTEAPAVEPRAVPKGPNSVFNMAG
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQHISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAEDVTVADIIIAVDEPLDATQCGGKGSCEGTKHHDGHCMTHELWSTLNQK
CCCCCHHHHHCCCCEEEHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
MVEYLDSVSLKDLVDQQRSREGATAVLRDRRTEAPAVEPRAVPKGPNSVFNMAG
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]