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The map label for this gene is alr [H]

Identifier: 186476117

GI number: 186476117

Start: 1526499

End: 1527590

Strand: Reverse

Name: alr [H]

Synonym: Bphy_1359

Alternate gene names: 186476117

Gene position: 1527590-1526499 (Counterclockwise)

Preceding gene: 186476120

Following gene: 186476116

Centisome position: 43.91

GC content: 64.19

Gene sequence:

>1092_bases
ATGTCTTTACGAAAATATCCCATGCCGCGCCCAGTCTCAGCCACGATTCACACTGCCGCTCTCGCCAATAATCTCGCTGT
CGCCCGTCGCTACGCGCCGAAGTCCAAGATCTGGGCTGTCGTCAAGGCCAATGCGTACGGTCACGGACTCGCGCGGGCAT
TCCCAGGCTTGCGCGCAACCGACGGCTTTGGTTTGCTCGACCTCGAAGAAGCGGTGAAGTTGCGTGAATTGGGGTGGGCG
GGGCCGATTTTGTTGCTGGAGGGCTTTTTCCGGCCCACCGATATCGACGTCATCGACCGTTATAGTCTGACCACGGCGCT
GCATTCGGACGAGCAGTTGCGCATGCTGGAAATGGCGCGCCTGTCCAAGCCCGTCAATATCCAGTTAAAGATGAACAGCG
GCATGAACCGCCTCGGCTATACGCCGGAGAAGTTCCGTGCAGCCTGGGAACGTGCGCGGGCCTGCCAGGGCGTCGGCCAG
ATCACGTTGATGACCCATTTCTCGGATGCCGACAGCGAGCGCGGCATCTCGCATCAGATGGAAGCATTCGAGCGTGGCGC
ACAGGGCATTGCGGGCGCGCGCAGCCTCGCCAATTCGGCCGCCACGCTGTGGTATCCGGAAGCGCATTTCGACTGGGTGC
GCCCGGGCGTGATGCTGTACGGCGCGTCGCCGTCGGGCGTAAGCTCGGCGATCAAGGACACGGGCCTGCAGCCGGCCATG
ACGCTTGCTTCGGAACTCATCGCCGTGCAGACGCTCGCGCAAGGGCAGACGATCGGCTATGGCTCGACCTTCACGGCGCG
CGAAGGCATGCGCATCGGCGTGGTCGCGTGCGGCTATGCGGACGGTTATCCGCGCGTCGCGCCGGAGGGTACGCCCATCA
TCGTCGACGGCATCCGTACGCGCATCGTCGGTCGTGTGTCGATGGACATGATCACCGTCGATCTCACGCCTTGCCCGCAG
GCGAACGTCGGCTCGCGTGTGGAGCTGTGGGGCGCCCAACTGCCCGTCGATGACGTCGCGCAGTCGTGCGGCACGATCGG
CTACGAGCTTGTGTGCGCCGTCGCGCCGCGCGTGCCCGTACGAGCCGAGTGA

Upstream 100 bases:

>100_bases
ATCATGAAAATAGTCGAATCCCGACTAGCAGAATCCTTGATCGCATTGTCGAGCTTGCCATCGGCGCGTTGCAAACACGC
TGTAAGCTACTGATTCGCCA

Downstream 100 bases:

>100_bases
CACGTGCCTCTATCGCACTTCGCGAGGCGCACCTCGCGCCGCACATAACGAACAACGACATGTAACGAAACAAGTTGGCT
AAACAGAAAACGTTGTACAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRATDGFGLLDLEEAVKLRELGWA
GPILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMARLSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQ
ITLMTHFSDADSERGISHQMEAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAM
TLASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRTRIVGRVSMDMITVDLTPCPQ
ANVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPVRAE

Sequences:

>Translated_363_residues
MSLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRATDGFGLLDLEEAVKLRELGWA
GPILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMARLSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQ
ITLMTHFSDADSERGISHQMEAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAM
TLASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRTRIVGRVSMDMITVDLTPCPQ
ANVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPVRAE
>Mature_362_residues
SLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRATDGFGLLDLEEAVKLRELGWAG
PILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMARLSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQI
TLMTHFSDADSERGISHQMEAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAMT
LASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRTRIVGRVSMDMITVDLTPCPQA
NVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPVRAE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=57.7903682719547, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=45.1704545454545, Blast_Score=300, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39219; Mature: 39087

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRAT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCC
DGFGLLDLEEAVKLRELGWAGPILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMAR
CCCCCEEHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQITLMTHFSDADSERGISHQM
CCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
EAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAM
HHHHHHHCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHH
TLASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRT
HHHHHHHHHHHHHCCCEECCCCCEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEECHHH
RIVGRVSMDMITVDLTPCPQANVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPV
HHHHEEEEEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHEECCCCCCC
RAE
CCC
>Mature Secondary Structure 
SLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRAT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCC
DGFGLLDLEEAVKLRELGWAGPILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMAR
CCCCCEEHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQITLMTHFSDADSERGISHQM
CCCCEEEEEEECCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
EAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAM
HHHHHHHCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHH
TLASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRT
HHHHHHHHHHHHHCCCEECCCCCEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEECHHH
RIVGRVSMDMITVDLTPCPQANVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPV
HHHHEEEEEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHHHEECCCCCCC
RAE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA