Click here to switch to the map view.

The map label for this gene is frr

Identifier: 186476093

GI number: 186476093

Start: 1494986

End: 1495546

Strand: Reverse

Name: frr

Synonym: Bphy_1335

Alternate gene names: 186476093

Gene position: 1495546-1494986 (Counterclockwise)

Preceding gene: 186476094

Following gene: 186476092

Centisome position: 42.99

GC content: 62.03

Gene sequence:

>561_bases
ATGTCTGTGGCTGACATCAAGAAAGGCGCTGAGCAGAAGATGCAGCGCTCGCTCGACGCGTTCAAGAACGATCTGTCGAA
GATCCGCACGGGCCGTGCCCACACGGGTCTGCTCGATCACATCCAGGTCGATTACTACGGCTCGCCTGTGCCGATCTCGC
AGGTCGCGAATCTGACGCTCGTCGACGCCCGCACGATCGGCGTGCAGCCGTGGGAAAAGAAGATGGTCGCCGTCGTCGAA
AAGGCGATCCGCGAATCGGATCTGGGCCTGAACCCGGCTTCGCACGGCGACGTGATCCGCGTGCCGATGCCGCCGCTCAC
GGAGGAGCGCCGCAAGGAACTCACCAAGGTCGTCAAGAGCGAAGGTGAAACGGCCAAGGTGGCCGTGCGCAACCTGCGCC
GCGACGCGAACGAGCAGCTCAAGAAGCTCGTGAAGGACAAGGAAATCTCGGAAGACGACGAGCGCCGCGCTGGCGACGAC
GTCCAGAAGCTGACGGACAAGTTCGTGGCCGAGATCGACAAGCTCGTGCAGACCAAGGAAGGCGAGATCATGACGGTTTG
A

Upstream 100 bases:

>100_bases
ACGTGTAAACTCTCTAGCATTCTGTGGGCTTGAACGCGGGCTCAGGCTGCGCCTCGCGCGCTGGCGGCTCGCATCGTTTT
GAAGGTTCGGAGGTTTAATC

Downstream 100 bases:

>100_bases
CGGTCTGGCGCAAACCAGACATGCAGACTTTCACTGATCATTGTTCCTTTCTCTAGCTTTACCCGACGGCCATGACCTAT
ACAAGCTCAACCGTTCGCGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADIKKGAEQKMQRSLDAFKNDLSKIRTGRAHTGLLDHIQVDYYGSPVPISQVANLTLVDARTIGVQPWEKKMVAVVE
KAIRESDLGLNPASHGDVIRVPMPPLTEERRKELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDD
VQKLTDKFVAEIDKLVQTKEGEIMTV

Sequences:

>Translated_186_residues
MSVADIKKGAEQKMQRSLDAFKNDLSKIRTGRAHTGLLDHIQVDYYGSPVPISQVANLTLVDARTIGVQPWEKKMVAVVE
KAIRESDLGLNPASHGDVIRVPMPPLTEERRKELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDD
VQKLTDKFVAEIDKLVQTKEGEIMTV
>Mature_185_residues
SVADIKKGAEQKMQRSLDAFKNDLSKIRTGRAHTGLLDHIQVDYYGSPVPISQVANLTLVDARTIGVQPWEKKMVAVVEK
AIRESDLGLNPASHGDVIRVPMPPLTEERRKELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDV
QKLTDKFVAEIDKLVQTKEGEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=31.6091954022989, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=57.1428571428571, Blast_Score=216, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=29.3785310734463, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_BURP8 (B2JIC3)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857563.1
- ProteinModelPortal:   B2JIC3
- SMR:   B2JIC3
- GeneID:   6242826
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1335
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20841; Mature: 20710

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADIKKGAEQKMQRSLDAFKNDLSKIRTGRAHTGLLDHIQVDYYGSPVPISQVANLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCHHHHCCCCE
VDARTIGVQPWEKKMVAVVEKAIRESDLGLNPASHGDVIRVPMPPLTEERRKELTKVVKS
ECHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
EGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDVQKLTDKFVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GEIMTV
CCEEEC
>Mature Secondary Structure 
SVADIKKGAEQKMQRSLDAFKNDLSKIRTGRAHTGLLDHIQVDYYGSPVPISQVANLTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCHHHHCCCCE
VDARTIGVQPWEKKMVAVVEKAIRESDLGLNPASHGDVIRVPMPPLTEERRKELTKVVKS
ECHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
EGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDVQKLTDKFVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GEIMTV
CCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA