Click here to switch to the map view.

The map label for this gene is atzB [H]

Identifier: 186476052

GI number: 186476052

Start: 1451620

End: 1453029

Strand: Reverse

Name: atzB [H]

Synonym: Bphy_1293

Alternate gene names: 186476052

Gene position: 1453029-1451620 (Counterclockwise)

Preceding gene: 186476055

Following gene: 186476050

Centisome position: 41.76

GC content: 65.04

Gene sequence:

>1410_bases
ATGACGTTGCAAACCAATGCAACCGGTGTGACGGGAACGGACGGGCCGCGCGGCCGGACGATGCTGGTCCGACACGCGGA
CGTGCTCGTCACGATGGACGGCGAACGTCGCGAGCTGCGCGACGGCGGTCTCTATATCGAAGACAACCGGATCGTCGCCG
TCGGTCCAACGCACACACTGCCGGGTACTGCGGACGCGATCCTCGACATGACGGGGCATCTCGTCATTCCTGGCCTCGTC
AACACGCACCATCACATGTATCAGAGCCTGACGCGCGCGATTCCCGCTGCACAGGACGCCGAGCTGTTCGGCTGGCTGAC
GAACCTCTATAAGGTGTGGGCGCACCTCACGCCGGAAATGATCGAAGTGTCGACGCTGACGGCGATGGCCGAACTGCTGC
TGTCCGGCTGCACTACGTCGAGCGACCACCTGTACATCTATCCGAACGGCAGCCGGCTCGATGACAGCATCGCGGCCGCA
CGGCGCATCGGCATGCGCTTTCATGCAAGCCGCGGGAGCATGAGCGTCGGACAGAAAGACGGCGGCCTGCCGCCCGATTG
CGTCGTCGAGCGGGAAGCGGACATTCTGAAGGACACCCAGCGCCTGATCGACGCGTATCACGACGCTGGCCGATACGCGA
TGCTGCGCGTCGTCGTTGCGCCGTGCTCGCCGTTTTCGGTGAGCCGCGATCTGATGCGCGAGTCGGCCGCACTGGCGCGC
CAATACGGCGTATCGCTGCACACGCATCTCGCGGAGAACGCGAACGATATTGCATACAGCCGCGAAAAGTTCGGCATGAC
GCCCGCAGAATATGCCGAGGAACTTGGCTGGATCGGTCCCGATGTATGGCACGCGCACTGCGTTCAACTCGATGACGCCG
GCATCCGGCTGTTCGCGCGCACGGGGACGGGCGTCGCGCATTGCCCGTGTTCCAACATGCGCCTTGCGTCGGGCATCGCG
CCCGTGAAGAAGATGCGGCTGGCGGGCGTCCCCGTCGGATTGGGGGTCGACGGATCGGCGTCGAATGACGGCGCGCAGAT
GGTCGCCGAGGTGCGACAGGCGATGCTGCTGCAGCGCGTCGGCTTCGGCCCGGACGCGATGACGGCACGCGAGGCGCTCG
AGATCGCGACGCTCGGCGGGGCGAAGGTGCTGAACCGCGACGATATCGGCGCGCTGGCGCCCGGCATGGCGGCGGACTTT
GTGTCGTTCGATCTGCGCCAGCCGCTGTTTGCGGGCGCGCTGCACGATCCCGTTGCGGCATTGGTGTTCTGCGCGCCCTC
GCAGGTGTCGACGAGTGTGATCGGCGGAAAGCAGGTGGTGAAAGACGGCGTGCTGACGACTGTCGATCTTGGCCCGGTAA
TCGAACGGCACAATCATCTCGCGAAGACGCTGTACCAAAGTGCAGCTTGA

Upstream 100 bases:

>100_bases
CGATGCAGCTTCGAGCGGCCACATGCAGTGGGCGCGGACAGGTGGCAGCATCGTGCATCGGCCTCATCGGCGGCGATAGA
GGGCAGCACTGGAGAAACGA

Downstream 100 bases:

>100_bases
GCAAAGCACTAAAACGCAAAGCGGCGGTTCGAGACCGCCGCCTGCACAGTAGTGCCTGTGCGTTACCTGTCGATCAACGT
CTTGGTCGCTTCGGCGACGA

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTLQTNATGVTGTDGPRGRTMLVRHADVLVTMDGERRELRDGGLYIEDNRIVAVGPTHTLPGTADAILDMTGHLVIPGLV
NTHHHMYQSLTRAIPAAQDAELFGWLTNLYKVWAHLTPEMIEVSTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAA
RRIGMRFHASRGSMSVGQKDGGLPPDCVVEREADILKDTQRLIDAYHDAGRYAMLRVVVAPCSPFSVSRDLMRESAALAR
QYGVSLHTHLAENANDIAYSREKFGMTPAEYAEELGWIGPDVWHAHCVQLDDAGIRLFARTGTGVAHCPCSNMRLASGIA
PVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQAMLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADF
VSFDLRQPLFAGALHDPVAALVFCAPSQVSTSVIGGKQVVKDGVLTTVDLGPVIERHNHLAKTLYQSAA

Sequences:

>Translated_469_residues
MTLQTNATGVTGTDGPRGRTMLVRHADVLVTMDGERRELRDGGLYIEDNRIVAVGPTHTLPGTADAILDMTGHLVIPGLV
NTHHHMYQSLTRAIPAAQDAELFGWLTNLYKVWAHLTPEMIEVSTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAA
RRIGMRFHASRGSMSVGQKDGGLPPDCVVEREADILKDTQRLIDAYHDAGRYAMLRVVVAPCSPFSVSRDLMRESAALAR
QYGVSLHTHLAENANDIAYSREKFGMTPAEYAEELGWIGPDVWHAHCVQLDDAGIRLFARTGTGVAHCPCSNMRLASGIA
PVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQAMLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADF
VSFDLRQPLFAGALHDPVAALVFCAPSQVSTSVIGGKQVVKDGVLTTVDLGPVIERHNHLAKTLYQSAA
>Mature_468_residues
TLQTNATGVTGTDGPRGRTMLVRHADVLVTMDGERRELRDGGLYIEDNRIVAVGPTHTLPGTADAILDMTGHLVIPGLVN
THHHMYQSLTRAIPAAQDAELFGWLTNLYKVWAHLTPEMIEVSTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAAR
RIGMRFHASRGSMSVGQKDGGLPPDCVVEREADILKDTQRLIDAYHDAGRYAMLRVVVAPCSPFSVSRDLMRESAALARQ
YGVSLHTHLAENANDIAYSREKFGMTPAEYAEELGWIGPDVWHAHCVQLDDAGIRLFARTGTGVAHCPCSNMRLASGIAP
VKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQAMLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFV
SFDLRQPLFAGALHDPVAALVFCAPSQVSTSVIGGKQVVKDGVLTTVDLGPVIERHNHLAKTLYQSAA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=397, Percent_Identity=24.6851385390428, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789249, Length=381, Percent_Identity=29.1338582677165, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082177, Length=381, Percent_Identity=25.4593175853018, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540282, Length=445, Percent_Identity=23.1460674157303, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=344, Percent_Identity=25.2906976744186, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643849, Length=443, Percent_Identity=23.4762979683973, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50247; Mature: 50116

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQTNATGVTGTDGPRGRTMLVRHADVLVTMDGERRELRDGGLYIEDNRIVAVGPTHTL
CEECCCCCCCCCCCCCCCCEEEEEECEEEEEECCCHHHHHCCCEEEECCEEEEECCCCCC
PGTADAILDMTGHLVIPGLVNTHHHMYQSLTRAIPAAQDAELFGWLTNLYKVWAHLTPEM
CCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHH
IEVSTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIGMRFHASRGSMSVGQKD
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GGLPPDCVVEREADILKDTQRLIDAYHDAGRYAMLRVVVAPCSPFSVSRDLMRESAALAR
CCCCCHHEECCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
QYGVSLHTHLAENANDIAYSREKFGMTPAEYAEELGWIGPDVWHAHCVQLDDAGIRLFAR
HHCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHEEEECCCCEEEEEE
TGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQAMLLQRV
CCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFDLRQPLFAGALHDPVAA
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
LVFCAPSQVSTSVIGGKQVVKDGVLTTVDLGPVIERHNHLAKTLYQSAA
HHEECCCHHHHHHHCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLQTNATGVTGTDGPRGRTMLVRHADVLVTMDGERRELRDGGLYIEDNRIVAVGPTHTL
EECCCCCCCCCCCCCCCCEEEEEECEEEEEECCCHHHHHCCCEEEECCEEEEECCCCCC
PGTADAILDMTGHLVIPGLVNTHHHMYQSLTRAIPAAQDAELFGWLTNLYKVWAHLTPEM
CCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHH
IEVSTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIGMRFHASRGSMSVGQKD
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GGLPPDCVVEREADILKDTQRLIDAYHDAGRYAMLRVVVAPCSPFSVSRDLMRESAALAR
CCCCCHHEECCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
QYGVSLHTHLAENANDIAYSREKFGMTPAEYAEELGWIGPDVWHAHCVQLDDAGIRLFAR
HHCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHEEEECCCCEEEEEE
TGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQAMLLQRV
CCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFDLRQPLFAGALHDPVAA
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
LVFCAPSQVSTSVIGGKQVVKDGVLTTVDLGPVIERHNHLAKTLYQSAA
HHEECCCHHHHHHHCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]